HUT64765A - Method for producing oxa-bicyclo[2.2.1] heptane-2,3-dimethanol-derivatives - Google Patents

Method for producing oxa-bicyclo[2.2.1] heptane-2,3-dimethanol-derivatives

Info

Publication number
HUT64765A
HUT64765A HU913991A HU399191A HUT64765A HU T64765 A HUT64765 A HU T64765A HU 913991 A HU913991 A HU 913991A HU 399191 A HU399191 A HU 399191A HU T64765 A HUT64765 A HU T64765A
Authority
HU
Hungary
Prior art keywords
dimethanol
bicyclo
heptane
derivatives
oxa
Prior art date
Application number
HU913991A
Other languages
English (en)
Other versions
HU913991D0 (en
HU210391B (en
Inventor
David Kronenthal
John K Thottathil
Ramesh N Patel
Laszlo J Szarka
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/629,762 external-priority patent/US5084581A/en
Priority claimed from US07/629,780 external-priority patent/US5084387A/en
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of HU913991D0 publication Critical patent/HU913991D0/hu
Publication of HUT64765A publication Critical patent/HUT64765A/hu
Publication of HU210391B publication Critical patent/HU210391B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/004Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU913991A 1990-12-18 1991-12-17 Method for preparing 7-oxabicyclo[2.2.1]heptane-2,3-dimethanol derivatives HU210391B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/629,762 US5084581A (en) 1990-12-18 1990-12-18 Process for preparing (3R-(3aα,4β,7ββ,7aα))-octahydro-4,7 epoxyisobenzofuranol from associated aldehydes
US07/629,780 US5084387A (en) 1990-12-18 1990-12-18 Microbiological hydrolysis for the preparation of (exo,exo)-7-oxabicyclo(2.2.1) heptane-2,3, monoacyl ester dimethanol

Publications (3)

Publication Number Publication Date
HU913991D0 HU913991D0 (en) 1992-03-30
HUT64765A true HUT64765A (en) 1994-02-28
HU210391B HU210391B (en) 1995-04-28

Family

ID=27091012

Family Applications (1)

Application Number Title Priority Date Filing Date
HU913991A HU210391B (en) 1990-12-18 1991-12-17 Method for preparing 7-oxabicyclo[2.2.1]heptane-2,3-dimethanol derivatives

Country Status (8)

Country Link
EP (1) EP0491548A3 (hu)
JP (1) JPH04295481A (hu)
AU (1) AU654310B2 (hu)
CA (1) CA2055572A1 (hu)
HU (1) HU210391B (hu)
IE (1) IE914159A1 (hu)
NZ (1) NZ240629A (hu)
PT (1) PT99836A (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2560613C (en) * 2004-03-22 2015-11-24 Solvay Pharmaceuticals Gmbh Oral pharmaceutical compositions of lipase-containing products, in particular of pancreatin, containing surfactants
JP4766856B2 (ja) * 2004-08-31 2011-09-07 ダイセル化学工業株式会社 酸素原子含有多環式化合物、重合性組成物及びその硬化物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1254577A (en) * 1983-05-13 1989-05-23 Peter W. Sprague 7-oxabicycloheptane prostaglandin intermediates and method for preparing same
US4663336A (en) * 1985-07-01 1987-05-05 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted diamide and its congener prostaglandin analogs useful in the treatment of thrombotic disease
NZ233600A (en) * 1989-06-12 1992-10-28 Squibb & Sons Inc 7-oxabicyclo(2.2.1)heptane imidazole prostaglandin analogs and pharmaceutical compositions
JP2891740B2 (ja) * 1990-03-30 1999-05-17 塩野義製薬株式会社 光学活性ノルボルナン系アミン誘導体の製造方法
IE920039A1 (en) * 1991-02-01 1992-08-12 Squibb & Sons Inc Heterocyclic amido prostaglandin analogs

Also Published As

Publication number Publication date
AU8968591A (en) 1992-06-25
HU913991D0 (en) 1992-03-30
PT99836A (pt) 1992-12-31
NZ240629A (en) 1994-10-26
CA2055572A1 (en) 1992-06-19
IE914159A1 (en) 1992-07-01
EP0491548A2 (en) 1992-06-24
AU654310B2 (en) 1994-11-03
JPH04295481A (ja) 1992-10-20
HU210391B (en) 1995-04-28
EP0491548A3 (en) 1992-09-09

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee