IL101535A - Isolation and purification of lantibiotics from fermentation broths - Google Patents

Isolation and purification of lantibiotics from fermentation broths

Info

Publication number
IL101535A
IL101535A IL10154592A IL10154592A IL101535A IL 101535 A IL101535 A IL 101535A IL 10154592 A IL10154592 A IL 10154592A IL 10154592 A IL10154592 A IL 10154592A IL 101535 A IL101535 A IL 101535A
Authority
IL
Israel
Prior art keywords
sepharose
methanol
volume
elution
subjecting
Prior art date
Application number
IL10154592A
Other languages
English (en)
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of IL101535A publication Critical patent/IL101535A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cosmetics (AREA)
  • Selective Calling Equipment (AREA)
  • Blow-Moulding Or Thermoforming Of Plastics Or The Like (AREA)
  • Air Bags (AREA)
  • Coin-Freed Apparatuses For Hiring Articles (AREA)
  • Telephone Function (AREA)
  • Saccharide Compounds (AREA)
  • Data Exchanges In Wide-Area Networks (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
IL10154592A 1991-04-11 1992-04-09 Isolation and purification of lantibiotics from fermentation broths IL101535A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB9107717A GB2254852B (en) 1991-04-11 1991-04-11 Lantibiotic isolation and purification by plural chromatography processes

Publications (1)

Publication Number Publication Date
IL101535A true IL101535A (en) 1996-07-23

Family

ID=10693100

Family Applications (2)

Application Number Title Priority Date Filing Date
IL101535A IL101535A0 (en) 1991-04-11 1992-04-09 Isolation and purification of lantibiotics
IL10154592A IL101535A (en) 1991-04-11 1992-04-09 Isolation and purification of lantibiotics from fermentation broths

Family Applications Before (1)

Application Number Title Priority Date Filing Date
IL101535A IL101535A0 (en) 1991-04-11 1992-04-09 Isolation and purification of lantibiotics

Country Status (19)

Country Link
EP (1) EP0508371B1 (es)
JP (1) JPH05252975A (es)
KR (1) KR100241040B1 (es)
AT (1) ATE163185T1 (es)
AU (1) AU653394B2 (es)
CA (1) CA2065748A1 (es)
DE (1) DE69224402T2 (es)
DK (1) DK0508371T3 (es)
ES (1) ES2112872T3 (es)
FI (1) FI921568L (es)
GB (1) GB2254852B (es)
GR (1) GR3026377T3 (es)
HU (1) HU213881B (es)
IL (2) IL101535A0 (es)
MX (1) MX9201677A (es)
NO (1) NO300639B1 (es)
NZ (1) NZ242298A (es)
TW (1) TW227567B (es)
ZA (1) ZA922616B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794181B2 (en) * 2002-10-09 2004-09-21 Immucell Corporation Method of purifying lantibiotics
JP2004248592A (ja) * 2003-02-20 2004-09-09 Sanpo Kk チロシナーゼ阻害剤及びその製造方法
JP5374260B2 (ja) * 2009-07-10 2013-12-25 静岡商工会議所 農業用資材

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8811760D0 (en) * 1988-05-18 1988-06-22 Thomae Gmbh Dr K Antibiotic
GB8811761D0 (en) * 1988-05-18 1988-06-22 Thomae Gmbh Dr K Biosynthetic process for preparation of chemical compounds
ATE95187T1 (de) * 1988-07-15 1993-10-15 Thomae Gmbh Dr K Verfahren zur gewinnung, isolierung und reinigung von epidermin.

Also Published As

Publication number Publication date
IL101535A0 (en) 1992-12-30
GB2254852A (en) 1992-10-21
TW227567B (es) 1994-08-01
KR100241040B1 (ko) 2000-02-01
FI921568A7 (fi) 1992-10-12
CA2065748A1 (en) 1992-10-12
FI921568A0 (fi) 1992-04-09
NZ242298A (en) 1993-11-25
ZA922616B (en) 1993-10-11
HU9201248D0 (en) 1992-06-29
ES2112872T3 (es) 1998-04-16
NO921446D0 (no) 1992-04-10
DK0508371T3 (da) 1998-09-23
EP0508371A1 (en) 1992-10-14
JPH05252975A (ja) 1993-10-05
AU653394B2 (en) 1994-09-29
KR920019945A (ko) 1992-11-20
MX9201677A (es) 1992-10-01
FI921568L (fi) 1992-10-12
GB9107717D0 (en) 1991-05-29
NO921446L (no) 1992-10-12
ATE163185T1 (de) 1998-02-15
GB2254852B (en) 1995-04-05
GR3026377T3 (en) 1998-06-30
AU1481392A (en) 1992-10-15
DE69224402D1 (de) 1998-03-19
HUT62943A (en) 1993-06-28
EP0508371B1 (en) 1998-02-11
HU213881B (en) 1997-11-28
DE69224402T2 (de) 1998-07-09
NO300639B1 (no) 1997-06-30

Similar Documents

Publication Publication Date Title
Hjertén Hydrophobic interaction chromatography
Kellner et al. Gallidermin: a new lanthionine‐containing polypeptide antibiotic
Tomita et al. Molecular biology of the pore-forming cytolysins from Staphylococcus aureus, α-and γ-hemolysins and leukocidin
EP0460882B1 (en) Lipopeptide deacylase
Ikigai et al. Mechanism of membrane damage by El Tor hemolysin of Vibrio cholerae O1
EP0342486B1 (en) Antibiotic
US4994555A (en) Process for recovery of glycopeptidic antibiotics
Sahl Staphylococcin 1580 is identical to the lantibiotic epidermin: implications for the nature of bacteriocins from gram-positive bacteria
CA1338002C (en) Glycopeptide recovery process
EP0508371B1 (en) Isolation and purification of lantibiotics
Folena-Wasserman et al. Affinity chromatography of glycopeptide antibiotics
US6218362B1 (en) Lantibiotic from Streptococcus mutans and uses thereof
US3184394A (en) Process for the preparation of enzymes, toxins and toxoids
Allgaier et al. Strategy for the purification of lantibiotics
Sztaricskai et al. High performance liquid chromatography (HPLC) of antibiotics of vancomycin type comparative studies
NAGARAJAN et al. The structural relationships of A82846B and its hydrolysis products with chloroorienticins A, B and C
Strickler et al. Rapid purification of staphylococcal enterotoxin B by high-pressure liquid chromatography
EP0339982A1 (en) Antibiotic compounds
Sitrin et al. Separation methodology
Fiedler et al. Purification of the hydrophilic antibiotics epidermin, gallidermin and nikkomycin Z by preparative reversed-phase HPLC
JPH01242598A (ja) 抗生物質a42867誘導体
Zanol et al. Isolation and structure determination of minor components of teicoplanin
DK175198B1 (da) Antibioticum, betegnet gallidermin, og syreadditionssalte deraf, farmaceutiske og kosmetiske præparater indeholdende forbindelserne og fremgangsmåde til forbindelsernes fremstilling samt deres anvendelse til fremstilling af et farmaceutisk præparat
Frey¹ et al. coagulase-negative staphylococci: re-isolation of epidermin
WO1989007612A1 (en) Novel antibiotic compounds

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees