IL116486A0 - Novel piperidine derivatives processes for their preparation and pharmaceutical compositions containing them - Google Patents
Novel piperidine derivatives processes for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL116486A0 IL116486A0 IL11648695A IL11648695A IL116486A0 IL 116486 A0 IL116486 A0 IL 116486A0 IL 11648695 A IL11648695 A IL 11648695A IL 11648695 A IL11648695 A IL 11648695A IL 116486 A0 IL116486 A0 IL 116486A0
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- piperidine derivatives
- novel piperidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9426029.6A GB9426029D0 (en) | 1994-12-22 | 1994-12-22 | Novel compounds |
| GBGB9512920.1A GB9512920D0 (en) | 1995-06-24 | 1995-06-24 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL116486A0 true IL116486A0 (en) | 1997-08-14 |
Family
ID=26306239
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL11648695A IL116486A0 (en) | 1994-12-22 | 1995-12-21 | Novel piperidine derivatives processes for their preparation and pharmaceutical compositions containing them |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5972951A (de) |
| EP (1) | EP0799226B1 (de) |
| JP (1) | JPH10510821A (de) |
| CN (1) | CN1175256A (de) |
| AP (1) | AP757A (de) |
| AR (1) | AR002011A1 (de) |
| AT (1) | ATE199085T1 (de) |
| AU (1) | AU697361B2 (de) |
| BG (1) | BG61977B1 (de) |
| BR (1) | BR9510419A (de) |
| CA (1) | CA2208244A1 (de) |
| CZ (1) | CZ192397A3 (de) |
| DE (1) | DE69520075T2 (de) |
| DZ (1) | DZ1957A1 (de) |
| ES (1) | ES2153907T3 (de) |
| FI (1) | FI972583A7 (de) |
| HU (1) | HUT77650A (de) |
| IL (1) | IL116486A0 (de) |
| MA (1) | MA23753A1 (de) |
| MX (1) | MX9704777A (de) |
| NO (1) | NO972910L (de) |
| NZ (1) | NZ298036A (de) |
| OA (1) | OA10610A (de) |
| PL (1) | PL321048A1 (de) |
| SK (1) | SK80297A3 (de) |
| TR (1) | TR199501597A2 (de) |
| WO (1) | WO1996019477A1 (de) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9519033D0 (en) * | 1995-09-18 | 1995-11-15 | Smithkline Beecham Plc | Treatment |
| GB9522845D0 (en) * | 1995-11-08 | 1996-01-10 | Smithkline Beecham Plc | Novel compounds |
| EP0861257A1 (de) * | 1995-11-08 | 1998-09-02 | Smithkline Beecham Plc | Spiro-piperdin derivate als 5ht-receptor antagonisten |
| EP0862565A1 (de) * | 1995-11-22 | 1998-09-09 | Smithkline Beecham Plc | Tricyclische spiroverbindungen als 5ht1d-rezeptorantagonisten |
| GB9605883D0 (en) * | 1996-03-20 | 1996-05-22 | Smithkline Beecham Plc | Novel compounds |
| GB9606396D0 (en) * | 1996-03-27 | 1996-06-05 | Smithkline Beecham Plc | Novel compounds |
| US6156783A (en) * | 1996-04-30 | 2000-12-05 | Smithkline Beecham P.L.C. | Spiroazabicyclic compounds, processes for their preparation, and their pharmaceutical use |
| FR2761069A1 (fr) * | 1997-03-20 | 1998-09-25 | Pf Medicament | Spiroamines derivees de dihydrobenzofuranes, leur preparation et leur application comme medicaments |
| AU6123699A (en) * | 1998-10-16 | 2000-05-08 | Takeda Chemical Industries Ltd. | Nitrogenous fused heterocycle compounds, process for the preparation thereof andagents containing the same |
| DE10051981A1 (de) | 2000-10-20 | 2002-05-02 | Bayer Ag | Substituierte Phenyluracile |
| US7144911B2 (en) | 2002-12-31 | 2006-12-05 | Deciphera Pharmaceuticals Llc | Anti-inflammatory medicaments |
| US7202257B2 (en) | 2003-12-24 | 2007-04-10 | Deciphera Pharmaceuticals, Llc | Anti-inflammatory medicaments |
| US7279576B2 (en) | 2002-12-31 | 2007-10-09 | Deciphera Pharmaceuticals, Llc | Anti-cancer medicaments |
| JP5043428B2 (ja) * | 2003-06-03 | 2012-10-10 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | ビアリール複素環式化合物ならびにその製造および使用方法 |
| US20050165025A1 (en) * | 2004-01-22 | 2005-07-28 | Recordati Ireland Ltd. | Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists |
| JP5304981B2 (ja) | 2005-12-26 | 2013-10-02 | 日産化学工業株式会社 | １，３−ビス（置換フェニル）−３−ヒドロキシプロパン−１−オンおよび２−プロペン−１−オン化合物およびその塩 |
| KR20100014811A (ko) | 2007-04-20 | 2010-02-11 | 데시페라 파마슈티칼스, 엘엘씨. | 골수증식성 질환 및 기타 증식성 질환의 치료에 유용한 키나제 억제제 |
| EP2520561B1 (de) | 2007-06-08 | 2016-02-10 | MannKind Corporation | IRE-1a-Inhibitoren |
| JP5349303B2 (ja) | 2007-06-27 | 2013-11-20 | 日産化学工業株式会社 | ３−ヒドロキシプロパン−１−オン化合物、２−プロペン−１−オン化合物およびイソキサゾリン化合物の製造方法 |
| CN105218565A (zh) | 2008-10-17 | 2016-01-06 | 泽农医药公司 | 螺羟吲哚化合物及其作为治疗剂的用途 |
| AR077252A1 (es) | 2009-06-29 | 2011-08-10 | Xenon Pharmaceuticals Inc | Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos |
| MX2012004373A (es) | 2009-10-14 | 2012-06-28 | Xenon Pharmaceuticals Inc | Metodos sinteticos para compuestos espiro-oxoindol. |
| CA2788440A1 (en) | 2010-02-26 | 2011-09-01 | Xenon Pharmaceuticals Inc. | Pharmaceutical compositions of spiro-oxindole compound for topical administration and their use as therapeutic agents |
| US8461179B1 (en) | 2012-06-07 | 2013-06-11 | Deciphera Pharmaceuticals, Llc | Dihydronaphthyridines and related compounds useful as kinase inhibitors for the treatment of proliferative diseases |
| TW201636017A (zh) | 2015-02-05 | 2016-10-16 | 梯瓦製藥國際有限責任公司 | 以螺吲哚酮化合物之局部調配物治療帶狀疱疹後遺神經痛之方法 |
| US11498903B2 (en) | 2017-08-17 | 2022-11-15 | Bristol-Myers Squibb Company | 2-(1,1′-biphenyl)-1H-benzodimidazole derivatives and related compounds as apelin and APJ agonists for treating cardiovascular diseases |
| IL276398B2 (en) | 2018-01-31 | 2026-03-01 | Deciphera Pharmaceuticals Llc | Combination therapy for mastocytosis |
| KR102708177B1 (ko) | 2018-01-31 | 2024-09-23 | 데시페라 파마슈티칼스, 엘엘씨. | 위장관 기질 종양의 치료를 위한 병용 요법 |
| EP3938363A1 (de) | 2019-03-11 | 2022-01-19 | Teva Pharmaceuticals International GmbH | Festkörperformen von ripretinib |
| WO2020183011A1 (en) | 2019-03-14 | 2020-09-17 | Institut Curie | Htr1d inhibitors and uses thereof in the treatment of cancer |
| PT4013412T (pt) | 2019-08-12 | 2026-03-18 | Deciphera Pharmaceuticals Llc | Ripretinib para o tratamento de tumores estromais gastrointestinais |
| LT4013412T (lt) | 2019-08-12 | 2026-03-25 | Deciphera Pharmaceuticals, Llc | Ripretinibas, skirtas virškinamojo trakto stromos navikų gydymui |
| CN115243681B (zh) | 2019-12-30 | 2024-08-16 | 德西费拉制药有限责任公司 | 1-(4-溴-5-(1-乙基-7-(甲氨基)-2-侧氧基-1,2-二氢-1,6-萘啶-3-基)-2-氟苯基)-3-苯基脲的组合物 |
| HRP20231699T1 (hr) | 2019-12-30 | 2024-05-10 | Deciphera Pharmaceuticals, Llc | Formulacije inhibitora amorfne kinaze i postupci njihove primjene |
| US12577211B2 (en) | 2020-06-29 | 2026-03-17 | Bacainn Biotherapeutics, Ltd. | Probenecid compounds for the treatment of inflammasome-mediated lung disease |
| US11779572B1 (en) | 2022-09-02 | 2023-10-10 | Deciphera Pharmaceuticals, Llc | Methods of treating gastrointestinal stromal tumors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9119932D0 (en) * | 1991-09-18 | 1991-10-30 | Glaxo Group Ltd | Chemical compounds |
| PT533268E (pt) | 1991-09-18 | 2002-02-28 | Glaxo Group Ltd | Derivados de benzanilida como antagonistas de 5-ht1d |
-
1995
- 1995-12-06 PL PL95321048A patent/PL321048A1/xx unknown
- 1995-12-06 DE DE69520075T patent/DE69520075T2/de not_active Expired - Fee Related
- 1995-12-06 US US08/849,932 patent/US5972951A/en not_active Expired - Fee Related
- 1995-12-06 WO PCT/EP1995/004889 patent/WO1996019477A1/en not_active Ceased
- 1995-12-06 NZ NZ298036A patent/NZ298036A/en unknown
- 1995-12-06 SK SK802-97A patent/SK80297A3/sk unknown
- 1995-12-06 EP EP95942116A patent/EP0799226B1/de not_active Expired - Lifetime
- 1995-12-06 MX MX9704777A patent/MX9704777A/es unknown
- 1995-12-06 FI FI972583A patent/FI972583A7/fi unknown
- 1995-12-06 CZ CZ971923A patent/CZ192397A3/cs unknown
- 1995-12-06 AU AU43433/96A patent/AU697361B2/en not_active Ceased
- 1995-12-06 CA CA002208244A patent/CA2208244A1/en not_active Abandoned
- 1995-12-06 HU HU9800158A patent/HUT77650A/hu unknown
- 1995-12-06 CN CN95197616A patent/CN1175256A/zh active Pending
- 1995-12-06 AT AT95942116T patent/ATE199085T1/de active
- 1995-12-06 JP JP8519477A patent/JPH10510821A/ja active Pending
- 1995-12-06 AP APAP/P/1997/001006A patent/AP757A/en active
- 1995-12-06 BR BR9510419A patent/BR9510419A/pt not_active Application Discontinuation
- 1995-12-06 ES ES95942116T patent/ES2153907T3/es not_active Expired - Lifetime
- 1995-12-19 TR TR95/01597A patent/TR199501597A2/xx unknown
- 1995-12-19 AR ARP950100629A patent/AR002011A1/es unknown
- 1995-12-20 DZ DZ950140A patent/DZ1957A1/fr active
- 1995-12-20 MA MA24106A patent/MA23753A1/fr unknown
- 1995-12-21 IL IL11648695A patent/IL116486A0/xx unknown
-
1997
- 1997-06-20 NO NO972910A patent/NO972910L/no unknown
- 1997-06-20 OA OA70033A patent/OA10610A/en unknown
- 1997-07-01 BG BG101715A patent/BG61977B1/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE199085T1 (de) | 2001-02-15 |
| AR002011A1 (es) | 1998-01-07 |
| OA10610A (en) | 2002-09-06 |
| NO972910L (no) | 1997-08-14 |
| MA23753A1 (fr) | 1996-07-01 |
| AP757A (en) | 1999-09-06 |
| EP0799226A1 (de) | 1997-10-08 |
| FI972583L (fi) | 1997-08-19 |
| MX9704777A (es) | 1997-10-31 |
| DZ1957A1 (fr) | 2002-02-17 |
| DE69520075T2 (de) | 2001-08-02 |
| TR199501597A2 (tr) | 1996-07-21 |
| DE69520075D1 (de) | 2001-03-15 |
| ES2153907T3 (es) | 2001-03-16 |
| HUT77650A (hu) | 1998-07-28 |
| NO972910D0 (no) | 1997-06-20 |
| EP0799226B1 (de) | 2001-02-07 |
| BG101715A (bg) | 1998-02-27 |
| CZ192397A3 (en) | 1997-09-17 |
| AU697361B2 (en) | 1998-10-01 |
| PL321048A1 (en) | 1997-11-24 |
| CA2208244A1 (en) | 1996-06-27 |
| SK80297A3 (en) | 1998-12-02 |
| BG61977B1 (bg) | 1998-11-30 |
| BR9510419A (pt) | 1998-05-19 |
| NZ298036A (en) | 1998-11-25 |
| CN1175256A (zh) | 1998-03-04 |
| AU4343396A (en) | 1996-07-10 |
| US5972951A (en) | 1999-10-26 |
| WO1996019477A1 (en) | 1996-06-27 |
| FI972583A0 (fi) | 1997-06-17 |
| JPH10510821A (ja) | 1998-10-20 |
| FI972583A7 (fi) | 1997-08-19 |
| AP9701006A0 (en) | 1997-07-31 |
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