IL123398A0 - Cloning methods for high strength spider silk proteins - Google Patents

Cloning methods for high strength spider silk proteins

Info

Publication number
IL123398A0
IL123398A0 IL12339896A IL12339896A IL123398A0 IL 123398 A0 IL123398 A0 IL 123398A0 IL 12339896 A IL12339896 A IL 12339896A IL 12339896 A IL12339896 A IL 12339896A IL 123398 A0 IL123398 A0 IL 123398A0
Authority
IL
Israel
Prior art keywords
high strength
spider silk
cloning methods
silk proteins
proteins
Prior art date
Application number
IL12339896A
Other languages
English (en)
Inventor
Richard M Basel
Glenn R Elion
Original Assignee
Agricola Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agricola Tech Inc filed Critical Agricola Tech Inc
Publication of IL123398A0 publication Critical patent/IL123398A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Woven Fabrics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Artificial Filaments (AREA)
IL12339896A 1995-08-22 1996-08-22 Cloning methods for high strength spider silk proteins IL123398A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51769495A 1995-08-22 1995-08-22
PCT/US1996/013767 WO1997008315A1 (fr) 1995-08-22 1996-08-22 Procedes de clonage servant a obtenir des proteines de soie d'araignee extremement resistantes

Publications (1)

Publication Number Publication Date
IL123398A0 true IL123398A0 (en) 1998-09-24

Family

ID=24060849

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12339896A IL123398A0 (en) 1995-08-22 1996-08-22 Cloning methods for high strength spider silk proteins

Country Status (7)

Country Link
EP (1) EP0848754A1 (fr)
JP (1) JPH11511325A (fr)
CN (1) CN1200145A (fr)
AU (1) AU7152996A (fr)
BR (1) BR9612625A (fr)
IL (1) IL123398A0 (fr)
WO (1) WO1997008315A1 (fr)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2774588B1 (fr) 1998-02-11 2000-05-05 Oreal Composition cosmetique ou dermatologique contenant au moins une proteine de soie d'arachnides naturelle, recombinante ou un analogue
US7157615B2 (en) 1998-03-17 2007-01-02 Nexia Biotechnologies, Inc. Production of biofilaments in transgenic animals
WO2001056626A1 (fr) * 2000-02-03 2001-08-09 Nexia Biotechnologies, Inc. Fil de suture chirurgical a base de soie d'araignee
US6608242B1 (en) * 2000-05-25 2003-08-19 E. I. Du Pont De Nemours And Company Production of silk-like proteins in plants
AR030426A1 (es) * 2000-06-09 2003-08-20 Ipk Inst Fuer Pflanzengenetik Proteinas sinteticas de tela de arana y su expresion en plantas transgenicas
CA2351274C (fr) * 2000-06-29 2011-04-26 Fiona F. Hunter Proteine isolee de soie de cocon de simulium vittatum et acides nucleiques encodant une telle proteine
US20110009960A1 (en) 2001-11-16 2011-01-13 Allergan, Inc. Prosthetic fabric structure
AU2003202330A1 (en) * 2002-01-11 2003-07-24 Nexia Biotechnologies, Inc. Recovery of biofilament proteins from biological fluids
AU2003249366A1 (en) 2002-06-24 2004-01-06 Tufts University Silk biomaterials and methods of use thereof
EP1601826B1 (fr) 2003-03-11 2011-06-29 Allergan, Inc. Implant en tissu de soie biocompatible
EP1613796B1 (fr) 2003-04-10 2017-03-22 Tufts University Solution aqueuse concentree de fibroine et utilisation
JP5748392B2 (ja) * 2005-10-05 2015-07-15 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション 絹タンパク質
DK1976868T3 (da) 2005-12-30 2015-04-20 Spiber Technologies Ab Edderkoppesilke-proteiner og fremgangsmåde til fremstilling af edderkoppesilke-proteiner
US20100028451A1 (en) 2006-09-26 2010-02-04 Trustees Of Tufts College Silk microspheres for encapsulation and controlled release
US9102916B2 (en) 2007-02-27 2015-08-11 Trustees Of Tufts College Tissue-engineered silk organs
WO2009023615A1 (fr) 2007-08-10 2009-02-19 Trustees Of Tufts College Compositions de soie tubulaires et procédés d'utilisation de celles-ci
WO2009100280A2 (fr) * 2008-02-07 2009-08-13 Trustees Of Tufts College Compositions d'hydroxyapatite et de soie en trois dimensions
JP5896743B2 (ja) 2008-10-09 2016-03-30 タフツ ユニバーシティー／トラスティーズ オブ タフツ カレッジ グリセロールを含有する改変された絹フィルム
WO2010057142A2 (fr) 2008-11-17 2010-05-20 Trustees Of Tufts College Modification de surface de matrices de fibroïne de soie avec du poly(éthylène glycol) utilisable comme barrière anti-adhérence et matériau anti-thrombose
US9308070B2 (en) 2008-12-15 2016-04-12 Allergan, Inc. Pliable silk medical device
US20130245757A1 (en) 2011-11-04 2013-09-19 Allergan, Inc. Method and device for improved soft tissue surgery
WO2011005381A2 (fr) 2009-06-01 2011-01-13 Trustees Of Tufts College Gélification de la fibroïne par traitement au vortex servant dans des applications d’encapsulation et d’administration
WO2011046652A2 (fr) 2009-07-20 2011-04-21 Trustees Of Tufts College Réflecteurs implantables et résorbables tout en protéines
US20110184227A1 (en) 2009-09-11 2011-07-28 Allergan, Inc. Prosthetic device and method of manufacturing the same
WO2011109691A2 (fr) 2010-03-05 2011-09-09 Trustees Of Tufts College Compositions ionomères à base de soie
CN103181025A (zh) 2010-04-12 2013-06-26 塔夫茨大学 丝电子部件
SG10201607262PA (en) 2010-08-30 2016-10-28 Harvard College A High Strength Chitin Composite Material and Method of Making
WO2012031282A2 (fr) 2010-09-03 2012-03-08 Tufts University/Trustees Of Tufts College Matériaux à base de soie dopés aux nanoparticules plasmoniques
JP5691052B2 (ja) * 2010-09-10 2015-04-01 岡本株式会社 組換え生物及び組換え生物により作られるタンパク質
JP2014502416A (ja) 2010-09-27 2014-01-30 タフツ ユニバーシティー／トラスティーズ オブ タフツ カレッジ 絹ベースの圧電性材料
EP3495015B1 (fr) 2010-10-19 2022-12-07 Trustees Of Tufts College Micro-aiguilles à base de fibroïne de soie et leurs procédés de fabrication
WO2012145652A1 (fr) 2011-04-20 2012-10-26 Trustees Of Tufts College Revêtements de soie dynamiques pour dispositifs implantables
BR112013027057A2 (pt) 2011-04-21 2020-08-11 Trustees Of Tufts College composições e métodos para a estabilização de agentes ativos
US20140370094A1 (en) 2011-11-08 2014-12-18 Tufts University Silk-based scaffold platform for engineering tissue constructs
AU2012335122B2 (en) 2011-11-09 2016-09-22 Trustees Of Tufts College Injectable silk fibroin foams and uses thereof
JP6362540B2 (ja) 2011-11-09 2018-07-25 トラスティーズ・オブ・タフツ・カレッジＴｒｕｓｔｅｅｓ Ｏｆ Ｔｕｆｔｓ Ｃｏｌｌｅｇｅ 注射可能なシルクフィブロイン粒子およびその使用
US10126467B2 (en) 2011-12-05 2018-11-13 Tufts University Signal enhancement by silk photonic crystals
HK1201761A1 (en) 2011-12-29 2015-09-11 Trustees Of Tufts College Functionalization of biomaterials to control regeneration and inflammation responses
EP3884931A3 (fr) 2012-02-06 2021-12-01 Children's Medical Center, Corp. Biomatériau multicouche pour la régénération tissulaire et la cicatrisation de plaies
NL1039495C2 (nl) * 2012-03-27 2013-09-30 Jalila Essaidi Werkwijze ter vervaardiging van een huidsubstituut op basis van spinnenzijde alsmede draagstructuur vervaardigd onder toepassing van deze werkwijze en draagstructuur met doorgroeiende levende huid.
JP2015512944A (ja) 2012-04-13 2015-04-30 トラスティーズ・オブ・タフツ・カレッジＴｒｕｓｔｅｅｓ Ｏｆ Ｔｕｆｔｓ Ｃｏｌｌｅｇｅ 絹マイクロスフェアを調製するための方法および組成物
HK1207977A1 (en) 2012-04-25 2016-02-19 Trustees Of Tufts College Silk microspheres and methods for surface lubrication
WO2014012101A1 (fr) 2012-07-13 2014-01-16 Trustees Of Tufts College Compactage de poudre de soie pour fabrication de constructions à résistance mécanique et rigidité élevées
WO2014035798A1 (fr) 2012-08-30 2014-03-06 Sanofi Lyogels de soie pour la libération prolongée de produits thérapeutiques protéiques et procédés de fabrication et d'utilisation associés
EP2925822A4 (fr) 2012-11-27 2016-10-12 Univ Tufts Encres à base de biopolymères et leur utilisation
AU2014233480B2 (en) 2013-03-15 2018-08-09 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
WO2014152097A1 (fr) 2013-03-15 2014-09-25 Banner Pharmacaps Inc. Capsules à base de soie
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
US10464361B2 (en) 2013-03-15 2019-11-05 Tufts University Silk water lithography
US11009792B2 (en) 2013-03-15 2021-05-18 Tufts University All water-based nanopatterning
CN103194068B (zh) * 2013-04-08 2015-12-23 浙江大学 一种稳定丝素蛋白溶液的方法
WO2014176458A2 (fr) 2013-04-24 2014-10-30 Trustees Of Tufts College Dispositifs pour anastomose en biopolymère biorésorbable
WO2015048527A1 (fr) 2013-09-27 2015-04-02 Tufts University Hydrogels de soie optiquement transparents
US10925999B2 (en) 2013-10-08 2021-02-23 Trustees Of Tufts College Tunable covalently crosslinked hydrogels and methods of making the same
WO2015070108A1 (fr) 2013-11-08 2015-05-14 Tufts University Matériaux de nanofibrilles à base de peptides
WO2015134865A1 (fr) 2014-03-07 2015-09-11 Tufts University Conservation de produits périssables au moyen de biopolymères
WO2015178466A1 (fr) * 2014-05-21 2015-11-26 味の素株式会社 Procédé de production de protéines de type fibroïne
WO2016028797A1 (fr) 2014-08-18 2016-02-25 Allergan, Inc. Dispositif médical en soie pliable
PE20171791A1 (es) 2014-12-02 2017-12-28 Silk Therapeutics Inc Prendas de vestir de seda y productos de alto rendimiento y metodos para elaborarla
US10758645B2 (en) 2014-12-17 2020-09-01 Tufts University Injectable, flexible hydroxyapatite-silk foams for osteochondral and dental repair
US10874742B2 (en) 2015-03-12 2020-12-29 Tufts University Shape memory silk materials
CN108601675A (zh) 2015-07-20 2018-09-28 塔夫茨大学 生物可降解的丝质耳管
JP2018527978A (ja) 2015-07-28 2018-09-27 トラスティーズ オブ タフツ カレッジ ポリペプチドモノリス
CN105231565B (zh) * 2015-10-20 2018-01-16 杭州华水布艺有限公司 一种含冰凉材料的防刺防护面料
WO2017123383A2 (fr) 2015-12-17 2017-07-20 Trustees Of Tufts College Hydrogels de fibroïne de soie, procédés de formation et leurs utilisations
WO2017106631A1 (fr) 2015-12-18 2017-06-22 Tufts University Système de purification de solutions de soie, système de concentration et procédés associés
US11643444B2 (en) 2016-05-04 2023-05-09 Trustees Of Tufts College Silk nanofibrils and uses thereof
WO2018006037A1 (fr) 2016-07-01 2018-01-04 Trustees Of Tufts College Peau artificielle innervée
US11248313B2 (en) 2016-08-01 2022-02-15 Trustees Of Tufts College Biomimetic mechanical tension driven fabrication of nanofibrillar architecture
US20190275136A1 (en) 2016-09-19 2019-09-12 Vaxess Technologies, Inc. Vaccine formulations with increased stability
WO2018081159A1 (fr) 2016-10-24 2018-05-03 Trustees Of Tufts College Compositions multicouches biomimétiques
US10857262B2 (en) 2016-10-31 2020-12-08 Sofregen Medical, Inc. Compositions comprising low molecular weight silk fibroin fragments and plasticizers
WO2018136754A1 (fr) 2017-01-20 2018-07-26 Massachusetts Institute Of Technology Micro-dépôts polymères injectables pour administration locale contrôlée de médicament
WO2019067737A1 (fr) * 2017-09-27 2019-04-04 Silk, Inc. Matériaux comprenant de la soie recombinante et leurs procédés de préparation
WO2019089567A1 (fr) 2017-10-30 2019-05-09 Massachusetts Institute Of Technology Nanoparticules couche par couche pour une thérapie par cytokines dans le traitement du cancer
US20210085598A1 (en) 2018-04-03 2021-03-25 Vaxess Technologies, Inc. Microneedle comprising silk fibroin applied to a dissolvable base
WO2020023906A2 (fr) 2018-07-27 2020-01-30 Vaxess Technologies, Inc. Dispositifs de prélèvement d'échantillons biologiques à base de polymère et leurs utilisations
JP7737142B2 (ja) * 2018-11-28 2025-09-10 ボルト スレッズ インコーポレイテッド クモ糸タンパク質のアルカリ精製法
CN110106571A (zh) * 2019-04-09 2019-08-09 商文辉 一种蛛网纺织面料及其制备方法
WO2021002984A1 (fr) 2019-05-30 2021-01-07 Massachusetts Institute Of Technology Micro-aiguilles d'hydrogel fonctionnalisées par de l'acide nucléique peptidique pour l'échantillonnage et la détection d'acides nucléiques fluides interstitiels
KR20220083662A (ko) * 2019-09-16 2022-06-20 볼트 쓰레즈, 인크. 고전단 가용화를 통한 거미 실크 단백질의 단리 방법
US11738174B2 (en) 2019-10-15 2023-08-29 Sofregen Medical, Inc. Delivery devices for delivering and methods of delivering compositions
CN115397339B (zh) 2019-12-06 2025-04-08 塔夫茨大学理事会 组织再生多药物混合剂及其递送器械
US20240104583A1 (en) 2022-09-26 2024-03-28 Massachusetts Institute Of Technology Integrating Biopolymer Design with Physical Unclonable Functions for Anticounterfeiting and Product Traceability

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7691191A (en) * 1990-04-19 1991-11-11 United States Of America, As Represented By The Secretary Of The Army, The Recombinant spider silk proteins through genetic engineering
EP0452925B1 (fr) * 1990-04-20 2000-02-09 The University Of Wyoming ADN codante pour la protéine de la soie d'araignée, vecteur et cellule transformée la contenant, et produits

Also Published As

Publication number Publication date
JPH11511325A (ja) 1999-10-05
EP0848754A1 (fr) 1998-06-24
BR9612625A (pt) 1999-06-01
AU7152996A (en) 1997-03-19
CN1200145A (zh) 1998-11-25
WO1997008315A1 (fr) 1997-03-06

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