IL134577A0 - Rtd receptor - Google Patents

Rtd receptor

Info

Publication number
IL134577A0
IL134577A0 IL13457798A IL13457798A IL134577A0 IL 134577 A0 IL134577 A0 IL 134577A0 IL 13457798 A IL13457798 A IL 13457798A IL 13457798 A IL13457798 A IL 13457798A IL 134577 A0 IL134577 A0 IL 134577A0
Authority
IL
Israel
Prior art keywords
rtd
receptor
chimeras
ligand
antibodies
Prior art date
Application number
IL13457798A
Other languages
English (en)
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of IL134577A0 publication Critical patent/IL134577A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL13457798A 1997-08-26 1998-07-14 Rtd receptor IL134577A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91887497A 1997-08-26 1997-08-26
PCT/US1998/014552 WO1999010484A1 (fr) 1997-08-26 1998-07-14 Recepteur rtd

Publications (1)

Publication Number Publication Date
IL134577A0 true IL134577A0 (en) 2001-04-30

Family

ID=25441109

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13457798A IL134577A0 (en) 1997-08-26 1998-07-14 Rtd receptor

Country Status (12)

Country Link
US (1) US20050287635A1 (fr)
EP (1) EP1009817B1 (fr)
JP (1) JP2001513994A (fr)
AT (1) ATE443761T1 (fr)
AU (1) AU8485098A (fr)
CA (1) CA2301847A1 (fr)
DE (1) DE69841176D1 (fr)
DK (1) DK1009817T3 (fr)
ES (1) ES2331900T3 (fr)
IL (1) IL134577A0 (fr)
PT (1) PT1009817E (fr)
WO (1) WO1999010484A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506569B1 (en) 1997-05-30 2003-01-14 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor TR10
CA2292790A1 (fr) 1997-05-30 1998-12-03 Human Genome Sciences, Inc. Recepteur tr10 du facteur de necrose tumorale humain
EP0998561A4 (fr) * 1997-07-15 2004-08-18 Immunex Corp Recepteur de proteine trail
EP1187842B1 (fr) * 1999-05-28 2006-04-26 Human Genome Sciences, Inc. Protéine de fusion entre Fc et TR10, RECEPTEUR DE FACTEUR DE NECROSE TUMORALE HUMAIN
CN101633692A (zh) 1999-06-28 2010-01-27 杰南技术公司 利用二价金属离子制备Apo-2配体的方法
AU6928200A (en) * 1999-08-25 2001-03-19 Genome Therapeutics Corporation A transmembrane trap for isolating membrane bound proteins
MXPA03010747A (es) 2001-05-25 2004-03-02 Human Genome Sciences Inc Anticuerpos que se unen inmunoespecificamente a receptores de ligando inductor de apoptosis relacionado con factor de necrosis tumoral.
IL161051A0 (en) 2001-10-02 2004-08-31 Genentech Inc Apo-2 ligand variants and uses thereof
ES2351786T3 (es) 2001-11-13 2011-02-10 Genentech, Inc. Formulaciones con ligando apo2/trail y usos de las mismas.
CA2489348A1 (fr) 2002-06-24 2003-12-31 Genentech, Inc. Variants du ligand apo-2/trail et utilisations de ceux-ci
JP4940136B2 (ja) * 2004-06-28 2012-05-30 イエダ リサーチ アンド ディベロップメント カンパニー リミテッド キメラタンパク質およびその使用
PL1774037T3 (pl) 2004-08-06 2011-09-30 Genentech Inc Oznaczenia i sposoby wykorzystujące biomarkery
JP5186372B2 (ja) 2005-08-16 2013-04-17 ジェネンテック， インコーポレイテッド 細胞／組織においてｇａｌｎａｃ−ｔ１４発現を試験することによるａｐｏ２ｌ／ｔｒａｉｌに対するアポトーシス感受性

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3691016A (en) * 1970-04-17 1972-09-12 Monsanto Co Process for the preparation of insoluble enzymes
CA1023287A (fr) * 1972-12-08 1977-12-27 Boehringer Mannheim G.M.B.H. Procede de fixation d'une proteine sur un substrat
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US4195128A (en) * 1976-05-03 1980-03-25 Bayer Aktiengesellschaft Polymeric carrier bound ligands
US4330440A (en) * 1977-02-08 1982-05-18 Development Finance Corporation Of New Zealand Activated matrix and method of activation
CA1093991A (fr) * 1977-02-17 1981-01-20 Hideo Hirohara Traduction non-disponible
US4229537A (en) * 1978-02-09 1980-10-21 New York University Preparation of trichloro-s-triazine activated supports for coupling ligands
JPS6023084B2 (ja) * 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4342566A (en) * 1980-02-22 1982-08-03 Scripps Clinic & Research Foundation Solid phase anti-C3 assay for detection of immune complexes
US4399216A (en) * 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4419446A (en) * 1980-12-31 1983-12-06 The United States Of America As Represented By The Department Of Health And Human Services Recombinant DNA process utilizing a papilloma virus DNA as a vector
US4640835A (en) * 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
US4870009A (en) * 1982-11-22 1989-09-26 The Salk Institute For Biological Studies Method of obtaining gene product through the generation of transgenic animals
US4601978A (en) * 1982-11-24 1986-07-22 The Regents Of The University Of California Mammalian metallothionein promoter system
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4496689A (en) * 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
US4736866B1 (en) * 1984-06-22 1988-04-12 Transgenic non-human mammals
DE3675588D1 (de) * 1985-06-19 1990-12-20 Ajinomoto Kk Haemoglobin, das an ein poly(alkenylenoxid) gebunden ist.
US4676980A (en) * 1985-09-23 1987-06-30 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Target specific cross-linked heteroantibodies
US5010182A (en) * 1987-07-28 1991-04-23 Chiron Corporation DNA constructs containing a Kluyveromyces alpha factor leader sequence for directing secretion of heterologous polypeptides
US4971192A (en) * 1989-10-12 1990-11-20 Donnell Robert T Coin holding device
US5206161A (en) * 1991-02-01 1993-04-27 Genentech, Inc. Human plasma carboxypeptidase B
US5447851B1 (en) * 1992-04-02 1999-07-06 Univ Texas System Board Of Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells
FR2707882B1 (fr) * 1993-07-23 1997-08-01 Immunotech Sa Nouveaux kits thérapeutiques anti-médiateurs protéiques, procédé de préparation et compositions pharmaceutiques les renfermant.
US6506569B1 (en) * 1997-05-30 2003-01-14 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor TR10
CA2292790A1 (fr) * 1997-05-30 1998-12-03 Human Genome Sciences, Inc. Recepteur tr10 du facteur de necrose tumorale humain

Also Published As

Publication number Publication date
DE69841176D1 (en) 2009-11-05
ES2331900T3 (es) 2010-01-19
US20050287635A1 (en) 2005-12-29
EP1009817A1 (fr) 2000-06-21
WO1999010484A1 (fr) 1999-03-04
EP1009817B1 (fr) 2009-09-23
ATE443761T1 (de) 2009-10-15
JP2001513994A (ja) 2001-09-11
DK1009817T3 (da) 2010-01-18
AU8485098A (en) 1999-03-16
PT1009817E (pt) 2009-12-30
CA2301847A1 (fr) 1999-03-04

Similar Documents

Publication Publication Date Title
IL132067A0 (en) Apo-2 receptor
WO1999011791A3 (fr) Recepteurs et ligands de la famille du facteur de necrose tumorale, acides nucleiques codants et agents de liaison associes
IL193919A0 (en) DcR3 POLYPEPTIDE A TNFR HOMOLOG
IL196509A0 (en) Antibodies directed aganist polypeptides capable of binding to ldcam, and pharmaceutical compositions comprising the same
IL193886A0 (en) Antibodies that bind to ldcam sequences
IL187847A0 (en) Tie receptor tyrosine kinase ligand homologues
YU19903A (sh) Novi receptor nukleinskih kiselina i polipeptida
DE69841176D1 (en) Rtd receptor
AU4981101A (en) Subtilisin variants
NO2011003I2 (fr)
EP1005540A4 (fr) Proteines ikk-beta, acides nucleiques et procedes
CA2200423A1 (fr) Nouveaux recepteurs d'oestrogene
IL132496A0 (en) Mammalian cytokine-like factor 7
WO1996015144A3 (fr) Marqueur du gene du chromosome 21, compositions et procedes associes
MXPA00003885A (es) Quimiocinas con modificiaciones de la terminacion amino.
WO2004043403A3 (fr) Polypeptides synthetiques a domaine unique imitant l'apolipoproteine e et methodes d'utilisation
WO2001019861A3 (fr) Anticorps du recepteur d'apo-2
EP1005539A4 (fr) PROTEINES IKK-$g(a), ACIDES NUCLEIQUES ET PROCEDES
WO1998057983A3 (fr) Proteine de mammifere de type facteur de croissance nerveuse
WO1994026891A3 (fr) Ligands purifies de flt3 de mammiferes et leurs agonistes/antagonistes
ATE305037T1 (de) Peptide, die fähig sind die sh3-domäne des gap- proteins zu binden, ihre kodierende dns, ihre zubereitung und verwendung
ZA978503B (en) Vertebrate smoothened proteins
WO2000024771A3 (fr) Acides nucleiques codant pour des proteines semblables a l'osteoprotegerine et methodes d'utilisation associees
BG103627A (en) New ifn receptor 1-binding proteins, dna encoding them, and methods for the modulation of a cellular response for interferons
WO2000037634A3 (fr) Nouveaux polypeptides et acides nucleiques codant pour ceux-ci