IL149669A0 - NEW THERAPEUTIC COMBINATIONS OF (S) -2-(BENZYLAMINO-METHYL)-2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-e] INDOL-8-ONE AND NEUROLEPTICS FOR THE TREATMENT OR PREVENTION OF PSYCHOTIC DISORDERS - Google Patents

NEW THERAPEUTIC COMBINATIONS OF (S) -2-(BENZYLAMINO-METHYL)-2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-e] INDOL-8-ONE AND NEUROLEPTICS FOR THE TREATMENT OR PREVENTION OF PSYCHOTIC DISORDERS

Info

Publication number: IL149669A0
Authority: IL; Israel
Prior art keywords: dioxino; neuroleptics; benzylamino; indol; tetrahydro
Prior art date: 1999-12-10

Application number

IL14966900A

Other languages

English (en)

Original Assignee

Wyeth Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-10

Filing date

2000-12-07

Publication date

2002-11-10

2000-12-07 Application filed by Wyeth Corp filed Critical Wyeth Corp

2002-11-10 Publication of IL149669A0 publication Critical patent/IL149669A0/xx

Links

DYJIKHYBKVODAC-ZDUSSCGKSA-N (2s)-2-[(benzylamino)methyl]-2,3,7,9-tetrahydro-[1,4]dioxino[2,3-e]indol-8-one Chemical compound C([C@H]1COC=2C=CC3=C(C=2O1)CC(N3)=O)NCC1=CC=CC=C1 DYJIKHYBKVODAC-ZDUSSCGKSA-N 0.000 title 1
208000028017 Psychotic disease Diseases 0.000 title 1
230000002265 prevention Effects 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

IL14966900A 1999-12-10 2000-12-07 NEW THERAPEUTIC COMBINATIONS OF (S) -2-(BENZYLAMINO-METHYL)-2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-e] INDOL-8-ONE AND NEUROLEPTICS FOR THE TREATMENT OR PREVENTION OF PSYCHOTIC DISORDERS IL149669A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US45860799A	1999-12-10	1999-12-10
PCT/US2000/033060 WO2001041750A2 (en)	1999-12-10	2000-12-07	Combinations of (s)-2-(benzylamino-methyl)-2,3,8,9,-tetrahydro-7h-1,4-dioxino(2,3)-e indol-8-one and neuroleptics

Publications (1)

Publication Number	Publication Date
IL149669A0 true IL149669A0 (en)	2002-11-10

Family

ID=23821437

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
IL14966900A IL149669A0 (en)	1999-12-10	2000-12-07	NEW THERAPEUTIC COMBINATIONS OF (S) -2-(BENZYLAMINO-METHYL)-2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-e] INDOL-8-ONE AND NEUROLEPTICS FOR THE TREATMENT OR PREVENTION OF PSYCHOTIC DISORDERS
IL149669A IL149669A (en)	1999-12-10	2002-05-15	Combinations of (S) - 2) Benzylamino – methyl) 2,9,8,3,2 –– Tetrahydro-H7–1, 4 – Dioxino] E – 3,2 [Indole-8 – on and neuroleptic for the treatment or prevention of Psychotic arrangements

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
IL149669A IL149669A (en)	1999-12-10	2002-05-15	Combinations of (S) - 2) Benzylamino – methyl) 2,9,8,3,2 –– Tetrahydro-H7–1, 4 – Dioxino] E – 3,2 [Indole-8 – on and neuroleptic for the treatment or prevention of Psychotic arrangements

Country Status (20)

Country	Link
EP (1)	EP1235570A2 (pl)
JP (1)	JP5557409B2 (pl)
KR (1)	KR100772854B1 (pl)
CN (1)	CN1230164C (pl)
AR (1)	AR026756A1 (pl)
AU (1)	AU784211B2 (pl)
BR (1)	BR0016168A (pl)
CA (1)	CA2396351C (pl)
CZ (1)	CZ20021880A3 (pl)
EA (1)	EA005002B1 (pl)
HK (1)	HK1045942A1 (pl)
HU (1)	HUP0203309A3 (pl)
IL (2)	IL149669A0 (pl)
MX (1)	MXPA02005649A (pl)
NO (1)	NO20022739D0 (pl)
NZ (1)	NZ519381A (pl)
PL (1)	PL355292A1 (pl)
TW (1)	TWI222864B (pl)
WO (1)	WO2001041750A2 (pl)
ZA (1)	ZA200205484B (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW200517106A (en)	2003-10-29	2005-06-01	Wyeth Corp	Sustained release pharmaceutical compositions
EP1856126A2 (en)	2005-02-17	2007-11-21	Wyeth a Corporation of the State of Delaware	Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
JP2011511845A (ja) *	2008-02-13	2011-04-14	ターガセプト，インコーポレイテッド	アルファ７（α７）ニコチン作動薬と抗精神病薬との組合せ物
HRP20220739T1 (hr) *	2020-05-04	2022-08-19	Bioprojet Pharma	Upotreba dopaminskih d3 djelomičnih agonista za liječenje poremećaja središnjeg živčanog sustava
GB202014184D0 (en)	2020-09-09	2020-10-21	Johnson Matthey Plc	Modifed catalyst supports and catalysts supported thereon

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2987484B2 (ja) *	1995-03-16	1999-12-06	大塚製薬株式会社	カルボスチリル誘導体の製造方法
US5756532A (en) *	1995-11-06	1998-05-26	American Home Products Corporation	Aminomethyl-2 3 8 9-tetrahydro-7H-1 4-dioxino 2 3-E!-indol-8-ones and derivatives
GB9627005D0 (en) *	1996-12-27	1997-02-12	Knoll Ag	Therapeutic agents

2000
- 2000-12-07 CZ CZ20021880A patent/CZ20021880A3/cs unknown
- 2000-12-07 EP EP00982461A patent/EP1235570A2/en not_active Withdrawn
- 2000-12-07 HU HU0203309A patent/HUP0203309A3/hu unknown
- 2000-12-07 PL PL00355292A patent/PL355292A1/pl not_active Application Discontinuation
- 2000-12-07 NZ NZ519381A patent/NZ519381A/en unknown
- 2000-12-07 WO PCT/US2000/033060 patent/WO2001041750A2/en not_active Ceased
- 2000-12-07 BR BR0016168-3A patent/BR0016168A/pt not_active Application Discontinuation
- 2000-12-07 AU AU19490/01A patent/AU784211B2/en not_active Ceased
- 2000-12-07 JP JP2001543095A patent/JP5557409B2/ja not_active Expired - Lifetime
- 2000-12-07 HK HK02107378.5A patent/HK1045942A1/zh unknown
- 2000-12-07 CA CA002396351A patent/CA2396351C/en not_active Expired - Lifetime
- 2000-12-07 CN CNB008169527A patent/CN1230164C/zh not_active Expired - Lifetime
- 2000-12-07 IL IL14966900A patent/IL149669A0/xx active IP Right Grant
- 2000-12-07 AR ARP000106504A patent/AR026756A1/es unknown
- 2000-12-07 KR KR1020027007286A patent/KR100772854B1/ko not_active Expired - Fee Related
- 2000-12-07 MX MXPA02005649A patent/MXPA02005649A/es active IP Right Grant
- 2000-12-07 EA EA200200656A patent/EA005002B1/ru not_active IP Right Cessation
- 2000-12-08 TW TW089126071A patent/TWI222864B/zh not_active IP Right Cessation
2002
- 2002-05-15 IL IL149669A patent/IL149669A/en not_active IP Right Cessation
- 2002-06-07 NO NO20022739A patent/NO20022739D0/no not_active Application Discontinuation
- 2002-07-09 ZA ZA200205484A patent/ZA200205484B/xx unknown

Also Published As

Publication number	Publication date
CN1230164C (zh)	2005-12-07
AU784211B2 (en)	2006-02-23
CA2396351C (en)	2009-11-10
MXPA02005649A (es)	2004-09-10
EA005002B1 (ru)	2004-10-28
JP5557409B2 (ja)	2014-07-23
CA2396351A1 (en)	2001-06-14
WO2001041750A2 (en)	2001-06-14
EA200200656A1 (ru)	2002-12-26
NZ519381A (en)	2004-04-30
JP2003516350A (ja)	2003-05-13
CZ20021880A3 (cs)	2002-08-14
KR20030016207A (ko)	2003-02-26
EP1235570A2 (en)	2002-09-04
NO20022739L (no)	2002-06-07
TWI222864B (en)	2004-11-01
AR026756A1 (es)	2003-02-26
NO20022739D0 (no)	2002-06-07
HUP0203309A3 (en)	2004-12-28
KR100772854B1 (ko)	2007-11-02
WO2001041750A3 (en)	2002-02-14
BR0016168A (pt)	2002-08-20
ZA200205484B (en)	2003-12-31
HK1045942A1 (zh)	2002-12-20
PL355292A1 (pl)	2004-04-05
CN1409633A (zh)	2003-04-09
HUP0203309A2 (hu)	2003-01-28
AU1949001A (en)	2001-06-18
IL149669A (en)	2006-06-11

Legal Events

Date	Code	Title
2006-12-07	FF	Patent granted
2006-12-27	KB	Patent renewed
2007-02-12	KB	Patent renewed

Publication	Publication Date	Title
AU2604301A (en)	2001-07-16	Tnf inhibitors for the treatment of neurological, retinal and muscular disorders
AU6530600A (en)	2001-03-05	Use of neurotoxin for treating cardiac muscle disorders
HUP9700603A3 (en)	2001-08-28	Pharmaceutical preparation for the treatment of blood coagulation disorders
AU3112899A (en)	1999-10-18	Rf diathermy and faradic muscle stimulation treatment
HUP0100069A3 (en)	2002-04-29	4(3)substituted-4(3)-aminomethyl-pyran, or -thiopyran-piperidine derivatives, their preparation and their use in the treatment of neurological disorders
HUP0103839A3 (en)	2004-06-28	Use of certain drugs for treating nerve root injury
PL344304A1 (en)	2001-10-22	Combination therapy for treatment of bipolar disorders
EP1063990A4 (en)	2003-01-02	THERAPY FOR ESTROGEN RELATED DISORDERS
AU6910600A (en)	2001-03-19	Methods for the treatment of mental disorders
AU2001256855A1 (en)	2001-11-20	Preparation for the prevention and treatment of ocular disorders
AU5908300A (en)	2001-01-22	Prevention and treatment of amyloid-associated disorders
AU6330999A (en)	2000-04-17	Rhodanine derivatives for the treatment and prevention of metabolic bone disorders
AU5298699A (en)	2000-03-06	Dnazymes and methods for treating hpv-related disorders
AU7601400A (en)	2001-04-24	Treatment and prevention of hepatic disorders
AU1546101A (en)	2001-05-30	Pharmaceutical compositions comprising acetylcholinesterase antisense deoxynucleotides for the treatment of muscular and neuromuscular disorders
HUP0102436A3 (en)	2002-01-28	Use of reboxetin for preparation of medicament for nervous disorders
AU7106300A (en)	2001-04-10	Treatment of skin disorders
IL149669A0 (en)	2002-11-10	NEW THERAPEUTIC COMBINATIONS OF (S) -2-(BENZYLAMINO-METHYL)-2,3,8,9-TETRAHYDRO-7H-1,4-DIOXINO[2,3-e] INDOL-8-ONE AND NEUROLEPTICS FOR THE TREATMENT OR PREVENTION OF PSYCHOTIC DISORDERS
AU3338699A (en)	1999-10-18	Medical devices treated to discourage blood coagulation
CA2260863A1 (en)	1998-02-12	Treatment of psychotic disorders
GB0031654D0 (en)	2001-02-07	Apparatus for the diagnosis and therapy of neuro-muscular and other tissue disorders
PL347976A1 (en)	2002-05-06	Isonipecotamides for the treatment of integrin−mediated disorders
AU1399100A (en)	2000-06-19	Therapeutic treatment with immunogenic drugs
AU2002348324A1 (en)	2003-05-12	Methods and compositions for the treatment and diagnosis of pain disorders using 46566
GC0000176A (en)	2006-03-29	Pharmaceutical combination preparations for the treatment of cardiac disorders