IL33940A0 - Preparation of pyrazinamides and novel intermediates - Google Patents
Preparation of pyrazinamides and novel intermediatesInfo
- Publication number
- IL33940A0 IL33940A0 IL33940A IL3394070A IL33940A0 IL 33940 A0 IL33940 A0 IL 33940A0 IL 33940 A IL33940 A IL 33940A IL 3394070 A IL3394070 A IL 3394070A IL 33940 A0 IL33940 A0 IL 33940A0
- Authority
- IL
- Israel
- Prior art keywords
- pyrazinamides
- preparation
- novel intermediates
- intermediates
- novel
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title 1
- IPEHBUMCGVEMRF-UHFFFAOYSA-N pyrazinecarboxamide Chemical class NC(=O)C1=CN=CC=N1 IPEHBUMCGVEMRF-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80466369A | 1969-03-05 | 1969-03-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL33940A0 true IL33940A0 (en) | 1970-04-20 |
Family
ID=25189519
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL33940A IL33940A0 (en) | 1969-03-05 | 1970-02-23 | Preparation of pyrazinamides and novel intermediates |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US3573306A (fr) |
| BE (1) | BE746816A (fr) |
| IL (1) | IL33940A0 (fr) |
| NL (1) | NL7001141A (fr) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4196292A (en) * | 1977-06-29 | 1980-04-01 | Merck & Co., Inc. | 6-Substituted amiloride derivatives |
| FI820266L (fi) * | 1981-02-02 | 1982-08-03 | Ici Plc | Alkanolaminderivater |
| US6858615B2 (en) * | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
| US6858614B2 (en) * | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenolic guanidine sodium channel blockers |
| US6903105B2 (en) * | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
| US7375107B2 (en) * | 2003-08-18 | 2008-05-20 | Parion Sciences, Inc. | Alaphatic pyrazinoylguanidine sodium channel blockers |
| US20090253714A1 (en) * | 2003-08-20 | 2009-10-08 | Johnson Michael R | Methods of reducing risk of infection from pathogens |
| US7745442B2 (en) * | 2003-08-20 | 2010-06-29 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens |
| EP1715867A4 (fr) * | 2004-02-12 | 2009-04-15 | Merck & Co Inc | Amides bipyridyles en tant que modulateurs du r cepteur-5 metabotropique du glutamate |
| US20100105702A1 (en) * | 2005-05-03 | 2010-04-29 | Darren Mansfield | Heterocyclylethylamide derivatives |
| US20070021439A1 (en) * | 2005-07-25 | 2007-01-25 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers |
| MX2010006421A (es) * | 2007-12-10 | 2010-06-25 | Novartis Ag | Compuestos organicos. |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| US9056867B2 (en) | 2011-09-16 | 2015-06-16 | Novartis Ag | N-substituted heterocyclyl carboxamides |
| CN108658876A (zh) | 2012-12-17 | 2018-10-16 | 帕里昂科学公司 | 3,5-二氨基-6-氯-n-(n-(4-苯基丁基)甲脒基)吡嗪-2-甲酰胺化合物 |
| CA2895512C (fr) | 2012-12-17 | 2021-10-19 | Parion Sciences, Inc. | Derives de chloro-pyrazine carboxamide utiles dans le traitement de maladies favorisees par une hydratation insuffisante des muqueuses |
| US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
| UY36034A (es) | 2014-03-18 | 2015-09-30 | Astrazeneca Ab | Derivados de 3,5-diamino-6-cloro-pirazina-2-carboxamida y sales farmaceuticamente aceptables de estos |
| AR126669A1 (es) * | 2021-08-02 | 2023-11-01 | Eurofarma Laboratorios S A | COMPUESTOS N-ACILIDRAZÓNICOS INHIBIDORES DE Nav 1.7 Y/O Nav 1.8, SUS PROCESOS DE OBTENCIÓN, COMPOSICIONES, USOS, MÉTODOS DE TRATAMIENTO DE ESTOS Y KITS |
-
1969
- 1969-03-05 US US804663A patent/US3573306A/en not_active Expired - Lifetime
-
1970
- 1970-01-27 NL NL7001141A patent/NL7001141A/xx unknown
- 1970-02-23 IL IL33940A patent/IL33940A0/xx unknown
- 1970-03-04 BE BE746816D patent/BE746816A/fr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BE746816A (fr) | 1970-09-04 |
| US3573306A (en) | 1971-03-30 |
| NL7001141A (fr) | 1970-09-08 |
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