IL88377A - Cloning and expression of a protein which modulates cellular response to type I interferon - Google Patents

Cloning and expression of a protein which modulates cellular response to type I interferon

Info

Publication number
IL88377A
IL88377A IL8837788A IL8837788A IL88377A IL 88377 A IL88377 A IL 88377A IL 8837788 A IL8837788 A IL 8837788A IL 8837788 A IL8837788 A IL 8837788A IL 88377 A IL88377 A IL 88377A
Authority
IL
Israel
Prior art keywords
protein
dna
cells
ifn
interferon
Prior art date
Application number
IL8837788A
Other languages
English (en)
Other versions
IL88377A0 (en
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL8837788A priority Critical patent/IL88377A/en
Publication of IL88377A0 publication Critical patent/IL88377A0/xx
Priority to AT89403131T priority patent/ATE122393T1/de
Priority to AU46661/89A priority patent/AU628895B2/en
Priority to CA002002862A priority patent/CA2002862C/en
Priority to ZA898680A priority patent/ZA898680B/xx
Priority to EP89403131A priority patent/EP0369877B1/en
Priority to ES89403131T priority patent/ES2071675T3/es
Priority to PCT/US1989/005197 priority patent/WO1990005737A1/en
Priority to JP50126490A priority patent/JP3156724B2/ja
Priority to DE68922582T priority patent/DE68922582T2/de
Priority to NO19903118A priority patent/NO311181B1/no
Priority to DK169890A priority patent/DK169890A/da
Priority to FI903577A priority patent/FI104495B/fi
Priority to US08/120,030 priority patent/US5358867A/en
Publication of IL88377A publication Critical patent/IL88377A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL8837788A 1988-11-14 1988-11-14 Cloning and expression of a protein which modulates cellular response to type I interferon IL88377A (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
IL8837788A IL88377A (en) 1988-11-14 1988-11-14 Cloning and expression of a protein which modulates cellular response to type I interferon
DE68922582T DE68922582T2 (de) 1988-11-14 1989-11-14 Klonierung und Expression eines Proteins, das die zellulare Reaktion auf Interferon vom Typ I moduliert.
ES89403131T ES2071675T3 (es) 1988-11-14 1989-11-14 Clonacion y expresion de una proteina que modula la respuesta celular al interferon de tipo i.
JP50126490A JP3156724B2 (ja) 1988-11-14 1989-11-14 タイプ１インターフェロンへの細胞応答を変えるタンパク質のクローニングおよび発現
CA002002862A CA2002862C (en) 1988-11-14 1989-11-14 Cloning and expression of a protein which modulates cellular response to type i interferon
ZA898680A ZA898680B (en) 1988-11-14 1989-11-14 Cloning and expression of a protein which modulates cellular response to type i interferon
EP89403131A EP0369877B1 (en) 1988-11-14 1989-11-14 Cloning and expression of a protein which modulates the cellular response to type I interferon
AT89403131T ATE122393T1 (de) 1988-11-14 1989-11-14 Klonierung und expression eines proteins, das die zellulare reaktion auf interferon vom typ i moduliert.
PCT/US1989/005197 WO1990005737A1 (en) 1988-11-14 1989-11-14 Cloning and expression of a protein which modulates cellular response to type i interferon
AU46661/89A AU628895B2 (en) 1988-11-14 1989-11-14 Cloning and expression of a protein which modulates cellular response to type i interferon
NO19903118A NO311181B1 (no) 1988-11-14 1990-07-12 Rekombinant DNA-molekyl som koder for et protein som modulerer cellul¶r respons overfor type I inter feron,fremgangsmåte til fremstilling av proteinet samt celler forproduksjon av proteinet
DK169890A DK169890A (da) 1988-11-14 1990-07-13 Kloning og ekspression af et protein, som modulerer det cellulaere respons paa type i interferon
FI903577A FI104495B (fi) 1988-11-14 1990-07-13 Soluvastetta tyypin I interferonille mukauttavan proteiinin kloonaus ja ilmeneminen
US08/120,030 US5358867A (en) 1988-11-14 1993-09-13 DNA cloning and expression of an L7 protein which modulates the 2'-5' oligosynthetase and H2-K*K response to type-I interferon

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL8837788A IL88377A (en) 1988-11-14 1988-11-14 Cloning and expression of a protein which modulates cellular response to type I interferon

Publications (2)

Publication Number Publication Date
IL88377A0 IL88377A0 (en) 1989-06-30
IL88377A true IL88377A (en) 1996-09-12

Family

ID=11059417

Family Applications (1)

Application Number Title Priority Date Filing Date
IL8837788A IL88377A (en) 1988-11-14 1988-11-14 Cloning and expression of a protein which modulates cellular response to type I interferon

Country Status (14)

Country Link
US (1) US5358867A (da)
EP (1) EP0369877B1 (da)
JP (1) JP3156724B2 (da)
AT (1) ATE122393T1 (da)
AU (1) AU628895B2 (da)
CA (1) CA2002862C (da)
DE (1) DE68922582T2 (da)
DK (1) DK169890A (da)
ES (1) ES2071675T3 (da)
FI (1) FI104495B (da)
IL (1) IL88377A (da)
NO (1) NO311181B1 (da)
WO (1) WO1990005737A1 (da)
ZA (1) ZA898680B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06510061A (ja) * 1991-08-30 1994-11-10 ジェネンテク，インコーポレイテッド Ｉｄｄｍの治療法
EP0563487A1 (en) * 1992-03-31 1993-10-06 Laboratoire Europeen De Biotechnologie S.A. Monoclonal antibodies against the interferon receptor, with neutralizing activity against type I interferon
US5821078A (en) 1992-09-03 1998-10-13 Yeda Research And Development Co. Ltd. Nucleic acid encoding interferon-α/β binding protein
IL106591A (en) * 1992-09-03 2008-03-20 Yeda Res & Dev Interferon alpha/beta binding protein, its preparation and pharmaceutical compositions containing it
CA2171955A1 (en) * 1993-09-17 1995-03-23 Michael G. Tovey Pharmaceutical composition comprising monoclonal antibodies against the interferon receptor, with neutralizing activity against type i interferon
US6740519B1 (en) 1997-11-03 2004-05-25 Mount Sinai School Of Medicine Immortalized, homozygous stat1-deficient mammalian cell lines and their uses
CN101318019B (zh) 2003-04-23 2012-08-29 梅达雷克斯公司 含1型干扰素拮抗剂的组合物及其在制备治疗炎症性肠病的药物中的用途
HUE035082T2 (en) 2004-06-21 2018-05-02 Squibb & Sons Llc Interferon alpha receptor 1 antibodies and their use
JP7308034B2 (ja) 2016-07-01 2023-07-13 リゾルブ セラピューティクス， エルエルシー 最適化二重ヌクレアーゼ融合物および方法
BR112020003670A2 (pt) 2017-08-22 2020-09-01 Sanabio, Llc receptores de interferon solúveis e usos dos mesmos

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808523A (en) * 1984-11-07 1989-02-28 Yeda Research And Development Co., Ltd. Constitutive production of human IFN-β1 by mammalian cells transformed by the IFN-β1 gene fused to an SV40 early promoter

Also Published As

Publication number Publication date
CA2002862A1 (en) 1990-05-14
JP3156724B2 (ja) 2001-04-16
ZA898680B (en) 1991-04-24
DE68922582D1 (de) 1995-06-14
AU4666189A (en) 1990-06-12
DK169890A (da) 1990-09-14
IL88377A0 (en) 1989-06-30
US5358867A (en) 1994-10-25
NO311181B1 (no) 2001-10-22
JPH03503366A (ja) 1991-08-01
NO903118D0 (no) 1990-07-12
AU628895B2 (en) 1992-09-24
FI104495B (fi) 2000-02-15
ATE122393T1 (de) 1995-05-15
CA2002862C (en) 1999-01-26
EP0369877B1 (en) 1995-05-10
FI903577A0 (fi) 1990-07-13
WO1990005737A1 (en) 1990-05-31
DE68922582T2 (de) 1995-09-07
DK169890D0 (da) 1990-07-13
ES2071675T3 (es) 1995-07-01
NO903118L (no) 1990-08-27
EP0369877A1 (en) 1990-05-23

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Legal Events

Date Code Title Description
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KB Patent renewed
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees