IT1298614B1 - Chelati complessi di manganese ad alta relassivita' in siero - Google Patents

Chelati complessi di manganese ad alta relassivita' in siero

Info

Publication number
IT1298614B1
IT1298614B1 ITMI980477A IT1298614B1 IT 1298614 B1 IT1298614 B1 IT 1298614B1 IT MI980477 A ITMI980477 A IT MI980477A IT 1298614 B1 IT1298614 B1 IT 1298614B1
Authority
IT
Italy
Prior art keywords
serum
manganese complex
high relaxation
complex chelates
chelates
Prior art date
Application number
Other languages
English (en)
Inventor
Fulvio Uggeri
Franco Fedeli
Marino Brocchetta
Luisella Calabi
Lino Paleari
Giuseppe Manfredi
Original Assignee
Bracco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Spa filed Critical Bracco Spa
Priority to ITMI980477 priority Critical patent/IT1298614B1/it
Priority to PCT/EP1999/001500 priority patent/WO1999045968A1/en
Priority to DE69903717T priority patent/DE69903717T2/de
Priority to EP99910336A priority patent/EP1061957B1/en
Priority to JP2000535381A priority patent/JP2002506050A/ja
Publication of ITMI980477A1 publication Critical patent/ITMI980477A1/it
Application granted granted Critical
Publication of IT1298614B1 publication Critical patent/IT1298614B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ITMI980477 1998-03-10 1998-03-10 Chelati complessi di manganese ad alta relassivita' in siero IT1298614B1 (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
ITMI980477 IT1298614B1 (it) 1998-03-10 1998-03-10 Chelati complessi di manganese ad alta relassivita' in siero
PCT/EP1999/001500 WO1999045968A1 (en) 1998-03-10 1999-03-09 Manganese chelates with high relaxivity in serum
DE69903717T DE69903717T2 (de) 1998-03-10 1999-03-09 Mangan (ii) chelate mit hoher in-serum relaxivität
EP99910336A EP1061957B1 (en) 1998-03-10 1999-03-09 Manganese (ii) chelates with high relaxivity in serum
JP2000535381A JP2002506050A (ja) 1998-03-10 1999-03-09 血清中で高い緩和性を有するマンガンキレート

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI980477 IT1298614B1 (it) 1998-03-10 1998-03-10 Chelati complessi di manganese ad alta relassivita' in siero

Publications (2)

Publication Number Publication Date
ITMI980477A1 ITMI980477A1 (it) 1999-09-10
IT1298614B1 true IT1298614B1 (it) 2000-01-12

Family

ID=11379243

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI980477 IT1298614B1 (it) 1998-03-10 1998-03-10 Chelati complessi di manganese ad alta relassivita' in siero

Country Status (5)

Country Link
EP (1) EP1061957B1 (it)
JP (1) JP2002506050A (it)
DE (1) DE69903717T2 (it)
IT (1) IT1298614B1 (it)
WO (1) WO1999045968A1 (it)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980148A (en) * 1985-02-06 1990-12-25 Mallinckrodt, Inc. Methods for enhancing magnetic resonance imaging
IT1213029B (it) * 1986-01-30 1989-12-07 Bracco Ind Chimica Spa Chelati di ioni metallici paramagnetici.
US5057302A (en) * 1987-02-13 1991-10-15 Abbott Laboratories Bifunctional chelating agents
IT1290417B1 (it) * 1996-08-02 1998-12-03 Bracco Spa Composti chelanti derivati di acidi poliamminopolicarbossilici, loro chelati con ioni metallici paramagnetici, loro preparazione ed
IT1283650B1 (it) * 1996-08-02 1998-04-23 Bracco Spa Chelati paramagnetici ad alta relassivita' in siero

Also Published As

Publication number Publication date
EP1061957B1 (en) 2002-10-30
JP2002506050A (ja) 2002-02-26
EP1061957A1 (en) 2000-12-27
WO1999045968A1 (en) 1999-09-16
DE69903717T2 (de) 2003-03-20
ITMI980477A1 (it) 1999-09-10
DE69903717D1 (de) 2002-12-05

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Legal Events

Date Code Title Description
0001 Granted