IT9022340A0 - Processo per la preparazione del (+)-cis-3-(acetossi)-5-(2-(dimetilammino)etil)-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin-4-(5h)-one cloridrato. - Google Patents

Processo per la preparazione del (+)-cis-3-(acetossi)-5-(2-(dimetilammino)etil)-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin-4-(5h)-one cloridrato.

Info

Publication number
IT9022340A0
IT9022340A0 IT9022340A IT2234090A IT9022340A0 IT 9022340 A0 IT9022340 A0 IT 9022340A0 IT 9022340 A IT9022340 A IT 9022340A IT 2234090 A IT2234090 A IT 2234090A IT 9022340 A0 IT9022340 A0 IT 9022340A0
Authority
IT
Italy
Prior art keywords
benzotiazepin
acetoxy
methoxyphenyl
dihydro
dimethylamino
Prior art date
Application number
IT9022340A
Other languages
English (en)
Other versions
IT9022340A1 (it
IT1244878B (it
Inventor
Elso Manghisi
Bruno Perego
Original Assignee
Lusochimica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lusochimica filed Critical Lusochimica
Publication of IT9022340A0 publication Critical patent/IT9022340A0/it
Priority to IT02234090A priority Critical patent/IT1244878B/it
Priority to ES92900248T priority patent/ES2070622T3/es
Priority to DE69108410T priority patent/DE69108410T2/de
Priority to EP92900248A priority patent/EP0561861B1/en
Priority to AT92900248T priority patent/ATE120192T1/de
Priority to CA002098114A priority patent/CA2098114C/en
Priority to AU90366/91A priority patent/AU9036691A/en
Priority to PCT/EP1991/002353 priority patent/WO1992010485A1/en
Priority to JP50037292A priority patent/JP3152658B2/ja
Priority to US08/074,841 priority patent/US5382663A/en
Publication of IT9022340A1 publication Critical patent/IT9022340A1/it
Application granted granted Critical
Publication of IT1244878B publication Critical patent/IT1244878B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
IT02234090A 1990-12-11 1990-12-11 Processo per la preparazione del (+)-cis-3-(acetossi)-5-!2-( dimetilammino)etil!-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin- 4-(5h)-one cloridrato IT1244878B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
IT02234090A IT1244878B (it) 1990-12-11 1990-12-11 Processo per la preparazione del (+)-cis-3-(acetossi)-5-!2-( dimetilammino)etil!-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin- 4-(5h)-one cloridrato
AT92900248T ATE120192T1 (de) 1990-12-11 1991-12-09 Verfahren zur herstellung von diltiazem.
DE69108410T DE69108410T2 (de) 1990-12-11 1991-12-09 Verfahren zur herstellung von diltiazem.
EP92900248A EP0561861B1 (en) 1990-12-11 1991-12-09 A process for the preparation of diltiazem
ES92900248T ES2070622T3 (es) 1990-12-11 1991-12-09 Un procedimiento para la preparacion de diltiazem.
CA002098114A CA2098114C (en) 1990-12-11 1991-12-09 A process for the preparation of diltiazem
AU90366/91A AU9036691A (en) 1990-12-11 1991-12-09 A process for the preparation of diltiazem
PCT/EP1991/002353 WO1992010485A1 (en) 1990-12-11 1991-12-09 A process for the preparation of diltiazem
JP50037292A JP3152658B2 (ja) 1990-12-11 1991-12-09 ジルチアゼムの製造方法
US08/074,841 US5382663A (en) 1990-12-11 1991-12-09 Process for the preparation of diltiazem

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02234090A IT1244878B (it) 1990-12-11 1990-12-11 Processo per la preparazione del (+)-cis-3-(acetossi)-5-!2-( dimetilammino)etil!-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin- 4-(5h)-one cloridrato

Publications (3)

Publication Number Publication Date
IT9022340A0 true IT9022340A0 (it) 1990-12-11
IT9022340A1 IT9022340A1 (it) 1992-06-11
IT1244878B IT1244878B (it) 1994-09-12

Family

ID=11194922

Family Applications (1)

Application Number Title Priority Date Filing Date
IT02234090A IT1244878B (it) 1990-12-11 1990-12-11 Processo per la preparazione del (+)-cis-3-(acetossi)-5-!2-( dimetilammino)etil!-2,3-diidro-2-(4-metossifenil)-1,5-benzotiazepin- 4-(5h)-one cloridrato

Country Status (10)

Country Link
US (1) US5382663A (it)
EP (1) EP0561861B1 (it)
JP (1) JP3152658B2 (it)
AT (1) ATE120192T1 (it)
AU (1) AU9036691A (it)
CA (1) CA2098114C (it)
DE (1) DE69108410T2 (it)
ES (1) ES2070622T3 (it)
IT (1) IT1244878B (it)
WO (1) WO1992010485A1 (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6938825B1 (en) 1989-04-24 2005-09-06 Ultracard, Inc. Data system
IT1255545B (it) * 1992-10-23 1995-11-09 Procedimento per la preparazione di diltiazem
ES2118292T3 (es) * 1994-09-16 1998-09-16 Orion Corp Fermion Metodo para la preparacion de 3-hidroxi-5-(2-dimetilamino)-etil)-2,3-dihidro-4-(metoxifenil)-1,5-benzotiazepin-4(5h)-ona y uso del producto para elaborar compuestos farmaceuticamente activos.
FI97725C (fi) * 1995-02-17 1997-02-10 Orion Yhtymae Oy Menetelmä diltiatseemin valmistamiseksi
WO1996038429A1 (en) * 1995-06-01 1996-12-05 Acic (Canada) Inc. Method for the manufacture of benzothiazepine derivatives
US6871787B1 (en) 1998-07-10 2005-03-29 Ultracard, Inc. Data storage card having a glass substrate and data surface region and method for using same
US7487908B1 (en) 1999-10-23 2009-02-10 Ultracard, Inc. Article having an embedded accessible storage member, apparatus and method for using same
US8397998B1 (en) 1999-10-23 2013-03-19 Ultracard, Inc. Data storage device, apparatus and method for using same
US7036739B1 (en) 1999-10-23 2006-05-02 Ultracard, Inc. Data storage device apparatus and method for using same
US6969006B1 (en) 2000-09-15 2005-11-29 Ultracard, Inc. Rotable portable card having a data storage device, apparatus and method for using same
FR3033701B1 (fr) 2015-03-19 2021-01-15 Univ Claude Bernard Lyon Nouvelles compositions antivirales pour le traitement de la grippe
US12594280B2 (en) 2015-03-19 2026-04-07 Universite Claude Bernard Lyon 1 Antiviral compositions for treating the flu
CN116143723A (zh) * 2022-12-07 2023-05-23 海南锦瑞制药有限公司 一种盐酸地尔硫卓的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3562257A (en) 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
IL71538A (en) * 1984-04-13 1987-07-31 Abic Ltd Process for the preparation of benzothiazepine derivatives
US4902684A (en) * 1988-06-20 1990-02-20 E. R. Squibb & Sons, Inc. Benzazepine and benzothiazepine derivatives
IT1226301B (it) * 1988-07-26 1990-12-27 Zambon Spa Processo per la preparazione di intermedi per la sintesi del diltiazem.

Also Published As

Publication number Publication date
IT9022340A1 (it) 1992-06-11
US5382663A (en) 1995-01-17
DE69108410D1 (de) 1995-04-27
CA2098114A1 (en) 1992-06-11
ATE120192T1 (de) 1995-04-15
EP0561861A1 (en) 1993-09-29
EP0561861B1 (en) 1995-03-22
ES2070622T3 (es) 1995-06-01
JPH06503317A (ja) 1994-04-14
AU9036691A (en) 1992-07-08
JP3152658B2 (ja) 2001-04-03
DE69108410T2 (de) 1995-08-10
CA2098114C (en) 2002-06-25
WO1992010485A1 (en) 1992-06-25
IT1244878B (it) 1994-09-12

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19951227