JP2000201648A - Nutritional composition and liquid diet - Google Patents

Nutritional composition and liquid diet

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Publication number
JP2000201648A
JP2000201648A JP11317369A JP31736999A JP2000201648A JP 2000201648 A JP2000201648 A JP 2000201648A JP 11317369 A JP11317369 A JP 11317369A JP 31736999 A JP31736999 A JP 31736999A JP 2000201648 A JP2000201648 A JP 2000201648A
Authority
JP
Japan
Prior art keywords
zinc
liquid food
yeast
nutritional composition
containing yeast
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP11317369A
Other languages
Japanese (ja)
Other versions
JP3720655B2 (en
Inventor
Takeshi Matsubara
猛 松原
Tadayuki Mineharu
忠行 峰晴
Hiroshi Kamogawa
弘 鴨川
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Factory Inc
Original Assignee
Otsuka Pharmaceutical Factory Inc
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Publication date
Application filed by Otsuka Pharmaceutical Factory Inc filed Critical Otsuka Pharmaceutical Factory Inc
Priority to JP31736999A priority Critical patent/JP3720655B2/en
Publication of JP2000201648A publication Critical patent/JP2000201648A/en
Application granted granted Critical
Publication of JP3720655B2 publication Critical patent/JP3720655B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Abstract

PROBLEM TO BE SOLVED: To provide a nutritious composition and a liquid food capable of supplying a necessary amount of zinc to the aged, etc., and having safety without damaging properties or feeling. SOLUTION: This nutritious composition is used for enterally supplying nutrition containing zinc-containing yeast and as a concrete example, 0-100 g/L of protein, 0-500 g/L of carbohydrate, 0-120 g/L of lipid, 0-50 g/L of dietary fiber and 0.05-50 g/L of zinc-containing yeast and a liquid food containing >=90 kcal/100 mL of energy.

Description

【発明の詳細な説明】DETAILED DESCRIPTION OF THE INVENTION

【0001】[0001]

【発明の属する技術分野】本発明は、経腸的栄養補給法
により亜鉛を補給するのに好適な栄養組成物および流動
食に関し、より詳しくは寝たきりの虚弱高齢者等に必要
量の亜鉛を含む各種栄養を経腸的に補給するのに好適な
栄養組成物および流動食に関する。
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a nutritional composition and a liquid diet suitable for supplementing zinc by an enteral nutritional supplementation method, and more particularly to a nutritional supplement containing a necessary amount of zinc for bedridden and weak elderly people. The present invention relates to a nutritional composition and a liquid diet suitable for enterally supplying various nutrients.

【0002】[0002]

【従来の技術】経腸的栄養補給法は、経口栄養組成物や
経管栄養組成物を用いる栄養補給法であって、代表的な
栄養組成物には流動食が挙げられる。流動食は、食物の
嚥下が困難な患者に投与されるほか、近時は寝たきり老
人等の高齢者等に対しても必要な栄養を補給する手段と
して広く使用されている。特に高齢者では、その30〜
40%がPEM(タンパク・エネルギー低栄養状態)に
あるといわれているだけに、流動食による栄養補給は重
要である。
2. Description of the Related Art Enteral nutrition is a nutritional supplementation method using an oral nutritional composition or a tube nutritional composition. A typical nutritional composition is a liquid diet. BACKGROUND ART Liquid foods are administered to patients who have difficulty swallowing foods, and recently, are widely used as a means for supplying necessary nutrition to elderly people such as bedridden elderly people. Especially for elderly people,
Nutrition by a liquid diet is important, as only 40% are said to be in PEM (protein and energy undernutrition).

【0003】しかし、流動食は人工的に調製されるもの
であるために、無害で消化管から吸収できる必須微量元
素が不足しがちである。微量元素のうち、特に亜鉛は、
生体における200種類以上の酵素の中心活性元素とし
て重要な役割を担っており、細胞の機能維持に重要な微
量金属である。
However, since liquid foods are prepared artificially, there is a tendency that there is a shortage of essential trace elements that are harmless and can be absorbed from the digestive tract. Of the trace elements, especially zinc,
It plays an important role as a central active element of more than 200 kinds of enzymes in living organisms, and is a trace metal important for maintaining the function of cells.

【0004】具体的には、亜鉛は創傷回復に重要な役割
を果たし、寝たきりの高齢者に多い褥瘡の回復を早める
働きがある。また、その他の亜鉛欠乏症としては、皮
疹、口内炎、舌炎、脱毛、爪変化、下痢等の腸性肢端皮
膚炎症、味覚異常、小人症のほか、免疫力低下などの症
例が知られている。ちなみに、亜鉛の推奨量は成人男子
で1日15mg、成人女子で1日12mgとされている
[第5次改定日本人の栄養所要量(第1出版社発
行)]。そのため、亜鉛を配合した流動食が種々提案さ
れているが、硫酸亜鉛等の無機塩が現状では法律上使用
できないため、亜鉛含有量の高い天然食品素材を添加し
なければならない。
[0004] Specifically, zinc plays an important role in wound healing, and has a function of accelerating the recovery of pressure sores, which are often found in bedridden elderly people. In addition, other zinc deficiencies are known, such as skin eruption, stomatitis, glossitis, hair loss, nail changes, intestinal extremity skin inflammation such as diarrhea, abnormal taste, dwarfism, and decreased immunity. I have. Incidentally, the recommended amount of zinc is 15 mg per day for adult boys and 12 mg per day for adult girls [fifth revised Japanese nutritional requirement (published by Daiichi Publisher)]. Therefore, various liquid foods containing zinc have been proposed. However, at present, inorganic salts such as zinc sulfate cannot be legally used, and natural food materials having a high zinc content must be added.

【0005】[0005]

【発明が解決しようとする課題】天然食品素材のうち亜
鉛含量の高いものはごくわずかである。しかも、流動食
は通常、濃厚な液状であるため、凝集沈殿などを起して
はならない。また、食品であるため風味も重要な要素と
なる。亜鉛含量の高い食品素材としては、牡蠣肉エキ
ス、ひまわりオリゴティン等が一般に知られており、特
開平9−132531号公報には、亜鉛を高濃度で含有
した牡蠣肉の抽出物を流動食に添加することが提案され
ている。しかし、これらの食品素材を濃厚な流動食に添
加した場合、該流動食が凝集したり、風味が劣化する等
の問題が生じる。
[0006] Very few natural food materials have a high zinc content. In addition, liquid foods are usually thick liquids, and must not cause coagulation and sedimentation. In addition, flavor is also an important factor because it is a food. As a food material having a high zinc content, oyster meat extract, sunflower oligotin and the like are generally known. Japanese Patent Application Laid-Open No. 9-132531 discloses an oyster meat extract containing a high concentration of zinc as a liquid food. It has been proposed to add. However, when these food materials are added to a thick liquid food, problems such as aggregation of the liquid food and deterioration of flavor arise.

【0006】また、ヒバマタ属に属する海草であるソル
ティアは亜鉛含量の高い食品素材として知られている
が、ソルティアは粒子径が大きいため、濃厚流動食への
分散性が悪く、製造直後より容器内に沈殿を生じるとい
う問題がある。そこで、結晶セルロース等の沈殿抑制物
質を添加して、ソルティアを濃厚流動食に分散させた場
合、濃厚流動食の粘度が上昇し、食感が悪くなる。ま
た、ソルティアを予め微粉砕しておくと、濃厚流動食へ
の分散性は向上するが、色調が悪くなるという問題があ
る。本発明の目的は、亜鉛欠乏症を予防するのに充分な
量の亜鉛を高齢者等に供給することができ、しかも安全
で性状や風味を損なうことがない栄養組成物および流動
食を提供することである。
[0006] Saltia, which is a seaweed belonging to the genus Hibamata, is known as a food material having a high zinc content. However, Saltia has a large particle size and is poorly dispersible in a thick liquid food. There is a problem that precipitation occurs. Therefore, when a precipitation inhibitor such as crystalline cellulose is added to disperse the saltia in the thick liquid food, the viscosity of the thick liquid food increases, and the texture deteriorates. Further, if Saltia is finely pulverized in advance, the dispersibility in a thick liquid food is improved, but there is a problem that the color tone is deteriorated. An object of the present invention is to provide a nutritional composition and a liquid food that can supply zinc to an elderly person or the like in an amount sufficient to prevent zinc deficiency, and that are safe and do not impair the properties or flavor. It is.

【0007】[0007]

【課題を解決するための手段】本発明者らは、流動食に
添加可能な亜鉛源として各種食品素材を鋭意検討した結
果、亜鉛含有酵母は、菌体内に亜鉛が取り込まれて強固
に結合しているため、亜鉛による風味の低下がなく、し
かも安全性が高く、濃厚な流動食への分散性にも優れて
いるという知見を得た。本発明の栄養組成物はかかる知
見に基づいて完成されたものであって、亜鉛含有酵母を
経腸的栄養補給用の栄養組成物に含有させたことを特徴
とする。上記亜鉛含有酵母を含有した本発明の栄養組成
物は、流動食、特に高栄養・高エネルギーの濃厚流動食
として好適に使用することができる。
Means for Solving the Problems The present inventors have intensively studied various food materials as a zinc source that can be added to a liquid food, and as a result, zinc containing yeast is taken up in the cells and strongly binds. Therefore, it was found that there was no decrease in flavor due to zinc, and that it was highly safe and excellent in dispersibility in a thick liquid food. The nutritional composition of the present invention has been completed on the basis of such findings, and is characterized in that zinc-containing yeast is contained in a nutritional composition for enteral nutrition. The nutritional composition of the present invention containing the above-mentioned zinc-containing yeast can be suitably used as a liquid food, particularly a highly nutrient and high energy concentrated liquid food.

【0008】また、本発明の栄養組成物は、亜鉛に加え
て、カルシウムとマグネシウムとを重量比で2:1〜
1:1の割合で含有しているのが好ましい。これによ
り、高齢者に多い虚血性心疾患の予防を図ることができ
る。本発明の流動食は、タンパク質0〜100g/L、
糖質0〜500g/L、脂質0〜120g/L、食物繊
維0〜50g/Lおよび亜鉛含有酵母0.05〜50g
/Lを含有し、エネルギーが100mL当たり90kc
al以上であることを特徴とする。これにより、寝たき
りの虚弱高齢者等に多いPEMや亜鉛欠乏症を確実に回
避し、必要な栄養やエネルギーを経腸的栄養補給法によ
り簡単に補給できるようになる。
The nutritional composition of the present invention comprises calcium and magnesium in a weight ratio of 2: 1 to 1 in addition to zinc.
It is preferable to contain it at a ratio of 1: 1. As a result, it is possible to prevent ischemic heart disease, which is common in the elderly. The liquid food of the present invention has a protein of 0 to 100 g / L,
Carbohydrate 0-500 g / L, lipid 0-120 g / L, dietary fiber 0-50 g / L and zinc-containing yeast 0.05-50 g
/ L, energy is 90kc per 100mL
a1 or more. As a result, PEM and zinc deficiency, which are often present in bedridden frail elderly people, can be reliably avoided, and necessary nutrition and energy can be easily supplied by enteral nutrition.

【0009】[0009]

【発明の実施の形態】本発明の栄養組成物は、亜鉛源と
して亜鉛含有酵母を含有したものである。亜鉛を含有す
る酵母としては、特に制限はなく、食用酵母を含め種々
の酵母が使用可能である。例えばSaccharomyces 属、To
rulopsis属、Mycotorula属、Torulaspora 属、Candida
属、Rhodotorula 属、Pichia属などに属する酵母が挙げ
られる。
BEST MODE FOR CARRYING OUT THE INVENTION The nutritional composition of the present invention contains a zinc-containing yeast as a zinc source. The yeast containing zinc is not particularly limited, and various yeasts including edible yeast can be used. For example, genus Saccharomyces, To
genus rulopsis, genus Mycotorula, genus Torulaspora, Candida
Yeasts belonging to the genera, Rhodotorula, Pichia and the like.

【0010】具体的には、Saccharomyces cerevisiae,
Saccharomyces uvarum, Saccharomyces rouxii IFO 043
9; Torulopsis utilis, Torulopsis candida IFO 0856;
Mycotorula japonica, Mycotorula lipolytica; Torul
aaspora delbrueckii; Candida sake, Candida tropic
alis; Hansenula anomala IFO 0140, Hansenula suaveo
lens; Saccharomycopsis fibligera IFO 1665, Sacchar
omycopsis lipolyticaATCC 20182; Rhodotorula rubra
IFO 0870; Pichia farinosa IFO 0607等が挙げられる。
[0010] Specifically, Saccharomyces cerevisiae,
Saccharomyces uvarum, Saccharomyces rouxii IFO 043
9; Torulopsis utilis, Torulopsis candida IFO 0856;
Mycotorula japonica, Mycotorula lipolytica; Torul
aaspora delbrueckii; Candida sake, Candida tropic
alis; Hansenula anomala IFO 0140, Hansenula suaveo
lens; Saccharomycopsis fibligera IFO 1665, Sacchar
omycopsis lipolyticaATCC 20182; Rhodotorula rubra
IFO 0870; Pichia farinosa IFO 0607 and the like.

【0011】特に好ましくは、食用酵母として使用され
ているもの、例えばSaccharomycescerevisiae, Sacchar
omyces uvarum, Saccharomyces rouxii, Saccharomycop
sisfibligera等に属するパン酵母、ビール酵母、ぶどう
酒酵母、清酒酵母、アルコール酵母、甘酒酵母、味噌醤
油酵母、飼料酵母、餌料酵母等が挙げられる。これらの
酵母に亜鉛を取り込ませるには、硫酸亜鉛、塩化亜鉛、
クエン酸亜鉛、酢酸亜鉛、酒石酸亜鉛、乳酸亜鉛等の亜
鉛塩を水に溶解させて得た亜鉛溶液中に酵母を懸濁さ
せ、必要に応じて加温しながら、攪拌または振とうさせ
ればよい。処理後、菌体を洗浄し、凍結乾燥して目的の
亜鉛含有酵母を得る。
Particularly preferably, those used as edible yeasts, for example, Saccharomycescerevisiae, Sacchar
omyces uvarum, Saccharomyces rouxii, Saccharomycop
Bread yeast, beer yeast, wine yeast, sake yeast, alcohol yeast, amazake yeast, miso soy sauce yeast, feed yeast, feed yeast, etc. belonging to sisfibligera and the like. To incorporate zinc into these yeasts, zinc sulfate, zinc chloride,
Suspending the yeast in a zinc solution obtained by dissolving zinc salts such as zinc citrate, zinc acetate, zinc tartrate, and zinc lactate in water, stirring or shaking while heating as necessary. Good. After the treatment, the cells are washed and freeze-dried to obtain the desired zinc-containing yeast.

【0012】このようにして得られた亜鉛含有酵母の亜
鉛含有量は、処理条件によって変化するが、通常、酵母
100gに対して亜鉛を約200〜6000mg含有し
ている。菌体内に取り込まれた亜鉛は容易に菌体外に流
出してくることがないため、亜鉛特有の金属味がなく、
安全性にも優れている。また、亜鉛含有酵母は平均粒径
が1〜4μmと微細である。そのため、流動食への分散
性に優れ、容易に凝集・沈降することがない。
[0012] The zinc content of the zinc-containing yeast thus obtained varies depending on the treatment conditions, but usually contains about 200 to 6000 mg of zinc per 100 g of yeast. Since the zinc taken into the cells does not easily flow out of the cells, there is no metallic taste unique to zinc,
Excellent safety. The zinc-containing yeast has a fine average particle size of 1 to 4 μm. Therefore, it is excellent in dispersibility in a liquid food, and does not easily aggregate and settle.

【0013】本発明の栄養組成物は経口栄養組成物およ
び経管栄養組成物のいずれをも含み、好ましい具体例と
しては流動食が挙げられる。栄養組成物中の亜鉛含有酵
母の含有量は亜鉛として0.1〜10mg/100m
L、好ましくは0.3〜5mg/100mLであるのが
よい。亜鉛含有量は1日当たりの亜鉛の所要量、さらに
分散安定性や風味等を考慮して決定される。
The nutritional composition of the present invention includes both an oral nutritional composition and a tube nutritional composition, and a preferred embodiment is a liquid diet. The content of the zinc-containing yeast in the nutritional composition is 0.1 to 10 mg / 100 m 2 as zinc.
L, preferably 0.3 to 5 mg / 100 mL. The zinc content is determined in consideration of the required amount of zinc per day, dispersion stability, flavor and the like.

【0014】流動食として利用する場合、このものはタ
ンパク質0〜100g/L、糖質0〜500g/L、脂
質0〜120g/L、食物繊維0〜50g/Lおよび亜
鉛含有酵母0.05〜50g/Lを含有する。ただし、
タンパク質、糖質および脂質は同時に0であってはなら
ず、流動食全体でエネルギーが100mL当たり90k
cal以上、好ましくは100kcal以上となるよう
にそれぞれの配合量を調整する。また、エネルギーは2
30kcal/100mL以下であるのが望ましい。
[0014] When used as a liquid food, it is 0-100 g / L of protein, 0-500 g / L of carbohydrate, 0-120 g / L of fat, 0-50 g / L of dietary fiber and 0.05-0.5 g of zinc-containing yeast. Contains 50 g / L. However,
Proteins, carbohydrates and lipids must not be zero at the same time, and the energy in the whole liquid meal is 90k / 100mL
The amount of each is adjusted so as to be at least cal, preferably at least 100 kcal. The energy is 2
It is desirably 30 kcal / 100 mL or less.

【0015】前記タンパク質としては、例えばカゼイン
またはカゼインナトリウム、カゼインカルシウム等のカ
ゼイン塩、鶏卵タンパク質、乳タンパク質、肉タンパク
質などの動物性タンパク質;大豆タンパク質などの植物
性タンパク質、大豆ペプチドなどのペプチド;ゼラチン
などが挙げられる。また、これらのタンパク質の分解物
やアミノ酸を使用してもよい。タンパク質は1種のみを
用いてもよく、2種以上を組み合わせて用いてもよい。
タンパク質は、流動食の全エネルギーの0〜30%、好
ましくは10〜25%を供給するのがよく、具体的には
含有量が0〜100g/L、好ましくは30〜65g/
Lである。
The protein includes, for example, casein or casein salts such as sodium caseinate and calcium caseinate; animal proteins such as chicken egg protein, milk protein and meat protein; vegetable proteins such as soy protein; peptides such as soy peptide; gelatin; And the like. In addition, degradation products or amino acids of these proteins may be used. One type of protein may be used alone, or two or more types may be used in combination.
The protein should supply 0-30%, preferably 10-25% of the total energy of the liquid food, and specifically has a content of 0-100 g / L, preferably 30-65 g / L.
L.

【0016】前記糖質としては、例えばマルトデキスト
リン、デキストリン、粉飴、さらにブドウ糖、果糖等の
単糖類、マルトース、乳糖等の二糖類、グラニュー糖、
オリゴ糖などがあげられる。糖質は1種のみを用いても
よく、2種以上を組み合わせて用いてもよい。糖質は流
動食の全エネルギーの0〜70%、好ましくは50〜7
0%を供給するのがよく、具体的には含有量が0〜50
0g/L、好ましくは100〜200g/Lである。
Examples of the saccharides include maltodextrin, dextrin, powdered candy, monosaccharides such as glucose and fructose, disaccharides such as maltose and lactose, granulated sugar,
Oligosaccharides and the like. One type of saccharide may be used alone, or two or more types may be used in combination. The sugar is 0 to 70% of the total energy of the liquid food, preferably 50 to 7
0% is preferably supplied. Specifically, the content is 0 to 50%.
0 g / L, preferably 100 to 200 g / L.

【0017】前記脂質としては、例えば米糠油、大豆
油、綿実油、サフラワー油、コーン油、菜種油、パーム
油、シソ油、エゴマ油、ヤシ油などの植物油;牛脂など
の動物油;魚油;MCT;さらに中鎖脂肪酸トリグリセ
リドその他の合成トリグリセリドなどが挙げられ、これ
らは1種のみを用いてもよく2種以上を組み合わせて用
いてもよい。脂質は流動食の全エネルギーの0〜50
%、好ましくは15〜30%を供給するのがよく、具体
的には含有量が0〜120g/L、好ましくは15〜3
5g/Lである。
The lipids include, for example, vegetable oils such as rice bran oil, soybean oil, cottonseed oil, safflower oil, corn oil, rapeseed oil, palm oil, perilla oil, perilla oil, coconut oil, etc .; animal oils such as beef tallow; fish oils; Furthermore, medium-chain fatty acid triglycerides and other synthetic triglycerides may be mentioned, and these may be used alone or in combination of two or more. Lipids are 0-50 of the total energy of the liquid diet
%, Preferably 15 to 30%, specifically, the content is 0 to 120 g / L, preferably 15 to 3 g / L.
It is 5 g / L.

【0018】前記食物繊維としては、例えばセルロー
ス、リグニン、レジスタントスターチ、ポリデキストロ
ース、オリゴ糖、グアガム酵素分解物などの難消化性の
多糖類等が挙げられる。食物繊維の含有量は、0〜50
g/L、好ましくは0.5〜45g/Lである。本発明
では、上記の各成分以外に従来より種々の流動食に添加
されているビタミン類、ミネラル類、乳化剤等を必要に
応じて添加することができる。
Examples of the dietary fiber include indigestible polysaccharides such as cellulose, lignin, resistant starch, polydextrose, oligosaccharide, and guar gum enzymatic decomposition product. Dietary fiber content is 0-50
g / L, preferably 0.5 to 45 g / L. In the present invention, in addition to the above components, vitamins, minerals, emulsifiers and the like conventionally added to various liquid foods can be added as necessary.

【0019】ビタミン類としては、例えばビタミンA、
ビタミンB1 、ビタミンB2 、ビタミンB6 、ビタミン
12、ビタミンC、ビタミンD、ビタミンE、ビタミン
K、ナイアシン、葉酸、パントテン酸などの脂溶性また
は水溶性のビタミン類が挙げられ、これらは1種のみを
用いてもよく、2種以上を組み合わせて用いてもよい。
上記した各ビタミンの配合量は、例えば第5次改定日本
人の栄養所要量(第1出版社発行)に記載の80歳男子
生活活動強度Iに記載の摂取量(目標摂取量)に従って
決定することができる。
As vitamins, for example, vitamin A,
Vitamin B 1, vitamin B 2, vitamin B 6, vitamin B 12, vitamin C, vitamin D, vitamin E, vitamin K, niacin, folic acid, fat-soluble or water-soluble vitamins such as pantothenic acid and the like, which One type may be used alone, or two or more types may be used in combination.
The amount of each of the above-mentioned vitamins is determined, for example, according to the intake amount (target intake amount) described in the 80-year-old male life activity intensity I described in the 5th revised Japanese nutritional requirement (published by the 1st publisher). be able to.

【0020】ミネラル類としては、例えばカルシウム、
鉄、ナトリウム、カリウム、リン、マグネシウム等が挙
げられ、これらは1種のみを用いてもよく、2種以上を
組み合わせて用いてもよい。これらのミネラル類の配合
量は、前記と同様に第5次改定日本人の栄養所要量に記
載の80歳男子生活活動強度Iに記載の摂取量(目標摂
取量)に従って決定することができる。
As minerals, for example, calcium,
Examples thereof include iron, sodium, potassium, phosphorus, and magnesium. These may be used alone or in combination of two or more. The amount of these minerals can be determined according to the intake (target intake) described in the 80-year-old male activity activity intensity I described in the Fifth Revised Nutritional Requirements for Japanese as described above.

【0021】その際、特にカルシウムとマグネシウムと
を重量比でCa:Mg=2:1〜1:1の割合となるよ
うに配合するのが心筋梗塞や虚血性心疾患等の疾患を予
防するうえで好ましい。マグネシウムの割合が上記範囲
より少ないと、虚血性心疾患等の種々の疾患の誘因とな
るおそれがある。
At this time, calcium and magnesium are particularly preferably blended in a weight ratio of Ca: Mg = 2: 1 to 1: 1 in order to prevent diseases such as myocardial infarction and ischemic heart disease. Is preferred. If the proportion of magnesium is lower than the above range, it may cause various diseases such as ischemic heart disease.

【0022】すなわち、マグネシウムは細胞内でエネル
ギー源となる酵素ATPアーゼを活性化する働きを有す
る。一方、細胞内に存在するカルシウムポンプはATP
アーゼにより活性化され、細胞内のカルシウム濃度を低
く保つ働きをしている。従って、血管平滑筋においても
適量のマグネシウムが存在すると、細胞内のカルシウム
濃度が低く保たれるため、血管平滑筋のれん縮が起こる
のが阻止され、虚血性心疾患が起こるのを予防できる。
また、マグネシウムの欠乏は神経疾患、精神疾患、不整
脈などの誘因ともなりうる。なお、カルシウムは骨粗鬆
症の予防に必要とされるものであり、配合量は通常約5
00〜1000mg/Lの範囲であるのが適当である。
That is, magnesium has the function of activating the enzyme ATPase which is an energy source in cells. On the other hand, the intracellular calcium pump is ATP
It is activated by ase and works to keep the intracellular calcium concentration low. Therefore, if an appropriate amount of magnesium is also present in vascular smooth muscle, intracellular calcium concentration is kept low, so that spasm of vascular smooth muscle is prevented, and ischemic heart disease can be prevented.
Also, magnesium deficiency can be a trigger for neurological disorders, psychiatric disorders, arrhythmias and the like. Calcium is required for the prevention of osteoporosis, and its amount is usually about 5%.
Suitably, it is in the range of 00 to 1000 mg / L.

【0023】上記乳化剤としては、例えばグリセリン脂
肪酸エステル、しょ糖脂肪酸エステル、ソルビタン脂肪
酸エステル、プロピレングリコール脂肪酸エステル、リ
ン脂質、アラビアガム、キサンタンガム、トラガントガ
ム、グアガム、ローカストビーンガムなどが挙げられ
る。また、上記した成分以外にも、例えば塩化ナトリウ
ム、グルタミン酸ナトリウム、クエン酸、クエン酸ナト
リウム、果汁などの呈味成分、コーヒー風味、抹茶風
味、ミルク風味などのフレーバーなどを適宜配合するこ
とができる。
Examples of the emulsifier include glycerin fatty acid ester, sucrose fatty acid ester, sorbitan fatty acid ester, propylene glycol fatty acid ester, phospholipid, gum arabic, xanthan gum, tragacanth gum, guar gum, locust bean gum and the like. In addition to the above components, for example, flavoring components such as sodium chloride, sodium glutamate, citric acid, sodium citrate, fruit juice, and flavors such as coffee flavor, matcha flavor, and milk flavor can be appropriately blended.

【0024】本発明の栄養組成物は、主として流動食の
形態で提供されるが、上記した各成分を混合し乾燥した
粉末状、固形状、ペースト状等の種々の形態であっても
よく、これらは直接または摂取時に水または湯に溶解な
いし分散させて摂取する。流動食の調製は常法に従って
行うことができる。すなわち、各成分を秤量し、水に投
入して充分に混合した後、乳化させ、レトルト・パウチ
内に充填密封し、殺菌処理を行うことによって流動食を
製造することができる。
The nutritional composition of the present invention is provided mainly in the form of a liquid food, but may be in various forms such as a powder, a solid, a paste or the like obtained by mixing and drying the above-mentioned components. These are taken directly or when dissolved or dispersed in water or hot water. Preparation of the liquid food can be performed according to a conventional method. That is, a liquid food can be produced by weighing each component, putting it in water, mixing well, emulsifying, filling and sealing in a retort pouch, and performing a sterilization treatment.

【0025】このようにして得られる流動食は、虚弱高
齢者等に必要な栄養・エネルギーを補給するだけでな
く、菌体内に亜鉛を保持し分散性に優れた亜鉛含有酵母
を含有しているため、従来の流動食では困難であった必
要量の亜鉛を安全にかつ風味を害することなく供給する
ことができる。
The liquid food thus obtained not only provides nutrition and energy necessary for the frail elderly, etc., but also contains zinc-containing yeast which retains zinc in the cells and has excellent dispersibility. Therefore, a required amount of zinc, which was difficult with a conventional liquid food, can be supplied safely and without impairing the flavor.

【0026】[0026]

【実施例】以下、実施例を挙げて本発明の栄養組成物を
説明するが、本発明は以下の実施例のみに限定されるも
のではない。
EXAMPLES Hereinafter, the nutritional composition of the present invention will be described with reference to examples, but the present invention is not limited to the following examples.

【0027】実施例1 表1に示す処方に従って各成分の秤量を行い、約65℃
の純水に表1に示す量のカゼインナトリウム、カゼイン
カルシウム、マルトデキストリン、ミネラル分散液、ポ
リグリセリン脂肪酸エステル、オリゴ糖、米糠油、菜種
油およびMCT(予めビタミンADオイルを分散させて
おく)を投入し混合した。上記ミネラル分散液には、亜
鉛源として亜鉛含有酵母(オリエンタル酵母工業(株)
製の商品名「ミネラル酵母−Zn」)を投入した。この
亜鉛含有酵母は、パン酵母Sacchromyces cerevisiae を
使用した亜鉛含量が約2重量%、平均粒子径約3.2μ
mの酵母粉末である。
Example 1 Each component was weighed according to the recipe shown in Table 1 and was weighed at about 65 ° C.
The amount of sodium caseinate, calcium caseinate, maltodextrin, mineral dispersion, polyglycerin fatty acid ester, oligosaccharide, rice bran oil, rapeseed oil, and MCT (vitamin AD oil are dispersed in advance) are added to pure water of Table 1. And mixed. In the above mineral dispersion, a zinc-containing yeast (Oriental Yeast Co., Ltd.) is used as a zinc source.
Trade name "mineral yeast-Zn"). This zinc-containing yeast has a zinc content of about 2% by weight using a baker's yeast Sacchromyces cerevisiae and an average particle size of about 3.2 μm.
m yeast powder.

【0028】各成分を混合後、混合液をキモミキサーに
投入し、約8000rpmで20分間粗乳化を行った。
ついで、60℃に加温し10分間静置した後、高圧乳化
機にて精乳化(500kgf/cm2 、2パス)を行った。得
られた乳化液を約20℃に冷却し、ビタミン類および香
料を添加後、メスアップを行った。充填タンクを約7℃
に冷却し、200rpmで攪拌しながら、得られた乳化
液を投入した。ついで、充填タンクからパウチへ本液2
25gを充填後、窒素置換を行いながらパウチを密封
し、121℃で14分間殺菌を行って濃厚流動食を得
た。
After mixing the components, the mixture was charged into a Kimo mixer and roughly emulsified at about 8000 rpm for 20 minutes.
Then, the mixture was heated to 60 ° C. and allowed to stand for 10 minutes, and then subjected to fine emulsification (500 kgf / cm 2 , 2 passes) using a high-pressure emulsifier. The obtained emulsion was cooled to about 20 ° C., vitamins and fragrance were added, and then a measuring procedure was performed. Filling tank at approx. 7 ℃
And the obtained emulsion was charged while stirring at 200 rpm. Then, from the filling tank to the pouch 2
After filling 25 g, the pouch was sealed while purging with nitrogen, and sterilized at 121 ° C. for 14 minutes to obtain a thick liquid food.

【0029】得られた濃厚流動食は100mL当たり1
00kcalのエネルギーを有する。また、この濃厚流
動食を分析した結果、亜鉛含量は1.67mg/100
mL、平均粒子径2.01μm、pH6.6、浸透圧4
50mOsmであり、性状は茶白色の乳濁液で、わずか
に甘い風味があった。この濃厚流動食は亜鉛含量、乳濁
液の安定性、風味などにおいて良好であった。
[0029] The obtained thick liquid food is 1 per 100 mL.
It has an energy of 00 kcal. As a result of analyzing the concentrated liquid food, the zinc content was 1.67 mg / 100.
mL, average particle size 2.01 μm, pH 6.6, osmotic pressure 4
It was 50 mOsm and had a brownish white emulsion with a slightly sweet flavor. This concentrated liquid food had good zinc content, emulsion stability, flavor and the like.

【0030】実施例2 表1に示す処方に従って各成分の秤量を行い、約65℃
の純水に表1に示す量の蛋白質、糖質、脂質、ミネラル
および乳化剤を投入し混合した後、混合液をホモミキサ
ーに投入し、約12000rpmで30分間粗乳化を行
った。ついで、高圧乳化機にて精乳化(500kgf/c
m2 、2パス)を行った。得られた乳化液を約20℃に
冷却し、ビタミン類および香料を添加後、メスアップを
行った。メスアップを行った液を充填タンクに移し、パ
ウチへ226g充填後、窒素置換を行いながらのパウチ
を密封し、123℃で14分間殺菌を行って、濃厚流動
食を得た。なお、ミネラル中の亜鉛源としては、実施例
1と同じ亜鉛含有酵母(オリエンタル酵母工業(株)製
の商品名「ミネラル酵母−Zn」)を使用した。得られ
た濃厚流動食は100mL当たり150kcalのエネ
ルギーを有する。また、この濃厚流動食を分析した結
果、亜鉛含量は1.7mg/100mL、pH6.62
であり、性状は茶白色の乳濁液で、わずかに甘い風味が
あった。この濃厚流動食は実施例1と同様に亜鉛含量、
乳濁液の安定性、風味などにおいて良好であった。
Example 2 Each component was weighed according to the formulation shown in Table 1 and was weighed at about 65 ° C.
The amounts of proteins, carbohydrates, lipids, minerals and emulsifiers shown in Table 1 were added to pure water and mixed, and then the mixture was poured into a homomixer, and roughly emulsified at about 12,000 rpm for 30 minutes. Then, fine emulsification (500kgf / c
m 2 , 2 passes). The obtained emulsion was cooled to about 20 ° C., vitamins and fragrance were added, and then a measuring procedure was performed. The messed-up liquid was transferred to a filling tank, and after filling 226 g of the pouch, the pouch was sealed while purging with nitrogen and sterilized at 123 ° C. for 14 minutes to obtain a thick liquid food. As the zinc source in the mineral, the same zinc-containing yeast as in Example 1 (trade name “mineral yeast-Zn” manufactured by Oriental Yeast Co., Ltd.) was used. The resulting concentrated liquid food has an energy of 150 kcal per 100 mL. Further, as a result of analyzing the concentrated liquid food, the zinc content was 1.7 mg / 100 mL, pH 6.62.
And a brown white emulsion with a slightly sweet flavor. This concentrated liquid food has a zinc content as in Example 1,
The emulsion had good stability and flavor.

【0031】実施例3 表1に示す量の蛋白質、糖質、脂質、ミネラルおよび乳
化剤と共に、同表に示す量の食物繊維(グアガム酵素分
解物)を投入し混合した以外は、実施例2と同様にして
濃厚流動食を得た。得られた濃厚流動食は100mL当
たり100kcalのエネルギーを有する。また、この
濃厚流動食を分析した結果、亜鉛含量は1.1mg/1
00mL、pH6.85であり、性状は茶白色の乳濁液
で、わずかに甘い風味があった。この濃厚流動食は実施
例1と同様に亜鉛含量、乳濁液の安定性、風味などにお
いて良好であった
Example 3 The same procedures as in Example 2 were carried out except that the amounts of dietary fiber (guar gum enzymatically decomposed product) shown in Table 1 were added and mixed together with the amounts of protein, carbohydrate, lipid, mineral and emulsifier shown in Table 1. Similarly, a thick liquid food was obtained. The resulting thick liquid food has an energy of 100 kcal per 100 mL. Further, as a result of analyzing the concentrated liquid food, the zinc content was 1.1 mg / 1.
It was 00 mL, pH 6.85 and had a brownish white emulsion with a slightly sweet flavor. This concentrated liquid food was excellent in zinc content, emulsion stability, flavor and the like as in Example 1.

【0032】[0032]

【表1】 [Table 1]

【0033】[0033]

【発明の効果】本発明によれば、亜鉛含有酵母を経腸的
栄養補給用の栄養組成物に含有させているので、安全
で、性状や風味を劣化させることがなく、そのため亜鉛
欠乏症の予防に充分な量の亜鉛を補給することができる
という効果がある。また、本発明では、亜鉛に加えて、
カルシウムとマグネシウムとを重量比で2:1〜1:1
の割合で含有させることにより、高齢者に多い虚血性心
疾患の予防を図ることができる。
According to the present invention, since the zinc-containing yeast is contained in the nutritional composition for enteral nutrition, it is safe and does not deteriorate its properties and flavor, thereby preventing zinc deficiency. Has the effect that a sufficient amount of zinc can be replenished. In the present invention, in addition to zinc,
Calcium and magnesium in a weight ratio of 2: 1 to 1: 1
, It is possible to prevent ischemic heart disease, which is common in the elderly.

【0034】上記亜鉛含有酵母を含有した本発明の流動
食は、寝たきりの虚弱高齢者等に亜鉛等の1日に必要な
栄養やエネルギーを経腸的栄養補給法により簡単に供給
できるという効果がある。
The liquid food of the present invention containing the above zinc-containing yeast has the effect of easily supplying nutrients and energy necessary for daily use such as zinc to bedridden elderly people by enteral nutrition. is there.

Claims (6)

【特許請求の範囲】[Claims] 【請求項1】亜鉛含有酵母を含有していることを特徴と
する経腸的栄養補給用の栄養組成物。
(1) A nutritional composition for enteral nutrition, comprising a zinc-containing yeast.
【請求項2】前記亜鉛含有酵母の含有量が、亜鉛換算で
0.1〜10mg/100mLである請求項1記載の組
成物。
2. The composition according to claim 1, wherein the content of the zinc-containing yeast is 0.1 to 10 mg / 100 mL in terms of zinc.
【請求項3】前記亜鉛含有酵母は平均粒径が1〜4μm
である請求項1または2記載の組成物。
3. The zinc-containing yeast has an average particle size of 1 to 4 μm.
The composition according to claim 1, wherein the composition is:
【請求項4】カルシウムとマグネシウムとを重量比で
2:1〜1:1の割合で含有した請求項1ないし3のい
ずれかに記載の組成物。
4. The composition according to claim 1, wherein calcium and magnesium are contained in a weight ratio of 2: 1 to 1: 1.
【請求項5】流動食の形態を有する請求項1〜4のいず
れかに記載の組成物。
5. The composition according to claim 1, which has a liquid food form.
【請求項6】タンパク質0〜100g/L、糖質0〜5
00g/L、脂質0〜120g/L、食物繊維0〜50
g/Lおよび亜鉛含有酵母0.05〜50g/Lを含有
し、エネルギーが100mL当たり90kcal以上で
あることを特徴とする流動食。
6. A protein of 0 to 100 g / L and a saccharide of 0 to 5
00 g / L, fat 0-120 g / L, dietary fiber 0-50
A liquid food containing g / L and 0.05 to 50 g / L of zinc-containing yeast, and having an energy of 90 kcal or more per 100 mL.
JP31736999A 1998-11-12 1999-11-08 Liquid food Expired - Lifetime JP3720655B2 (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006020600A (en) * 2004-07-09 2006-01-26 Q P Corp Food and drink
JP2006045217A (en) * 2004-07-08 2006-02-16 Taisho Pharmaceut Co Ltd Zinc-containing composition for oral administration
JP2010115151A (en) * 2008-11-13 2010-05-27 Morinaga Milk Ind Co Ltd Method for producing modified milk powder
JP5384333B2 (en) * 2007-04-27 2014-01-08 株式会社明治 Liquid nutritional composition containing whey protein at high concentration and method for producing the same

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006045217A (en) * 2004-07-08 2006-02-16 Taisho Pharmaceut Co Ltd Zinc-containing composition for oral administration
JP2006020600A (en) * 2004-07-09 2006-01-26 Q P Corp Food and drink
JP5384333B2 (en) * 2007-04-27 2014-01-08 株式会社明治 Liquid nutritional composition containing whey protein at high concentration and method for producing the same
JP2010115151A (en) * 2008-11-13 2010-05-27 Morinaga Milk Ind Co Ltd Method for producing modified milk powder

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