JP2017506627A5 - - Google Patents
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- Publication number
- JP2017506627A5 JP2017506627A5 JP2016550664A JP2016550664A JP2017506627A5 JP 2017506627 A5 JP2017506627 A5 JP 2017506627A5 JP 2016550664 A JP2016550664 A JP 2016550664A JP 2016550664 A JP2016550664 A JP 2016550664A JP 2017506627 A5 JP2017506627 A5 JP 2017506627A5
- Authority
- JP
- Japan
- Prior art keywords
- medicament
- salt
- medicament according
- agent
- carbamimidoamidobenzoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 2
- 229940122632 Enteropeptidase inhibitor Drugs 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 claims 1
- 229960005261 aspartic acid Drugs 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 206010012601 diabetes mellitus Diseases 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014025832 | 2014-02-13 | ||
| JP2014025832 | 2014-02-13 | ||
| PCT/JP2015/000639 WO2015122187A1 (en) | 2014-02-13 | 2015-02-12 | Fused heterocyclic compound |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018146459A Division JP6529649B2 (ja) | 2014-02-13 | 2018-08-03 | 縮合複素環化合物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017506627A JP2017506627A (ja) | 2017-03-09 |
| JP2017506627A5 true JP2017506627A5 (2) | 2018-03-08 |
| JP6383427B2 JP6383427B2 (ja) | 2018-08-29 |
Family
ID=52589729
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016550664A Active JP6383427B2 (ja) | 2014-02-13 | 2015-02-12 | 縮合複素環化合物 |
| JP2018146459A Active JP6529649B2 (ja) | 2014-02-13 | 2018-08-03 | 縮合複素環化合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018146459A Active JP6529649B2 (ja) | 2014-02-13 | 2018-08-03 | 縮合複素環化合物 |
Country Status (41)
| Country | Link |
|---|---|
| US (2) | US9346776B2 (2) |
| EP (1) | EP3105213B1 (2) |
| JP (2) | JP6383427B2 (2) |
| KR (1) | KR102378454B1 (2) |
| CN (1) | CN105980370B (2) |
| AR (1) | AR099400A1 (2) |
| AU (1) | AU2015216438B2 (2) |
| BR (1) | BR112016018455B1 (2) |
| CA (1) | CA2938191C (2) |
| CL (1) | CL2016001911A1 (2) |
| CR (1) | CR20160367A (2) |
| CY (1) | CY1121534T1 (2) |
| DK (1) | DK3105213T3 (2) |
| DO (1) | DOP2016000206A (2) |
| EA (1) | EA032201B1 (2) |
| EC (1) | ECSP16067137A (2) |
| ES (1) | ES2717113T3 (2) |
| GE (1) | GEP20176808B (2) |
| HR (1) | HRP20190369T1 (2) |
| HU (1) | HUE042709T2 (2) |
| IL (1) | IL246838B (2) |
| JO (1) | JO3472B1 (2) |
| LT (1) | LT3105213T (2) |
| MA (1) | MA39246A1 (2) |
| ME (1) | ME03422B (2) |
| MX (1) | MX368392B (2) |
| MY (1) | MY173607A (2) |
| NZ (1) | NZ722035A (2) |
| PE (1) | PE20161243A1 (2) |
| PH (1) | PH12016501582B1 (2) |
| PL (1) | PL3105213T3 (2) |
| PT (1) | PT3105213T (2) |
| RS (1) | RS58498B1 (2) |
| SG (1) | SG11201605654QA (2) |
| SI (1) | SI3105213T1 (2) |
| SM (1) | SMT201900175T1 (2) |
| TR (1) | TR201903892T4 (2) |
| TW (1) | TWI669297B (2) |
| UA (1) | UA118280C2 (2) |
| UY (1) | UY35994A (2) |
| WO (1) | WO2015122187A1 (2) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014230583B2 (en) * | 2013-03-13 | 2017-09-28 | Takeda Pharmaceutical Company Limited | Guanidinobenzoic acid ester compound |
| SI3105218T1 (sl) | 2014-02-13 | 2019-11-29 | Incyte Corp | Ciklopropilamini kot inhibitorji LSD1 |
| US9346776B2 (en) | 2014-02-13 | 2016-05-24 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound |
| US9527835B2 (en) | 2014-02-13 | 2016-12-27 | Incyte Corporation | Cyclopropylamines as LSD1 inhibitors |
| MX373103B (es) | 2014-02-13 | 2020-04-17 | Incyte Holdings Corp | Ciclopropilaminas como inhibidores de desmetilasa específica de lisina 1 (lsd1). |
| US9428470B2 (en) | 2014-02-13 | 2016-08-30 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| TWI687419B (zh) | 2014-07-10 | 2020-03-11 | 美商英塞特公司 | 作為ｌｓｄ１抑制劑之咪唑并吡啶及咪唑并吡嗪 |
| WO2016007722A1 (en) | 2014-07-10 | 2016-01-14 | Incyte Corporation | Triazolopyridines and triazolopyrazines as lsd1 inhibitors |
| TW201613925A (en) | 2014-07-10 | 2016-04-16 | Incyte Corp | Imidazopyrazines as LSD1 inhibitors |
| JP2018080109A (ja) * | 2015-03-16 | 2018-05-24 | 武田薬品工業株式会社 | 治療剤 |
| EP3275874B1 (en) * | 2015-03-27 | 2019-10-30 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound |
| EP3277689B1 (en) | 2015-04-03 | 2019-09-04 | Incyte Corporation | Heterocyclic compounds as lsd1 inhibitors |
| LT3334709T (lt) | 2015-08-12 | 2025-03-10 | Incyte Holdings Corporation | Lsd1 inhibitoriaus druskos |
| CN111542511A (zh) * | 2017-11-02 | 2020-08-14 | 宇部兴产株式会社 | 蛋白分解酶的双头型抑制剂 |
| JP7199774B2 (ja) * | 2018-05-09 | 2023-01-06 | エルジー・ケム・リミテッド | エンテロペプチダーゼ阻害活性を示す新規化合物 |
| EP3650440A4 (en) * | 2018-08-27 | 2020-11-25 | Scohia Pharma, Inc. | BENZOIC ESTER COMPOUND |
| WO2020047198A1 (en) | 2018-08-31 | 2020-03-05 | Incyte Corporation | Salts of an lsd1 inhibitor and processes for preparing the same |
| US20220281866A1 (en) | 2019-07-19 | 2022-09-08 | Janssen Pharmaceutica Nv | 5,8-disubstituted-[1,2,4]triazolo[1,5-a]pyridinyl and 5,8-disubstituted-imidazo[1,2-a]pyridine derivatives useful as inhibitors of enteropeptidase |
| JP7327788B2 (ja) * | 2019-08-06 | 2023-08-16 | 学校法人福岡大学 | 糖化産物生成抑制剤及び医薬組成物 |
| WO2021166899A1 (ja) * | 2020-02-17 | 2021-08-26 | 宇部興産株式会社 | インクレチン様物質と組み合わせて使用するための消化管プロテアーゼ阻害剤を含む薬剤 |
| CN111544599B (zh) * | 2020-07-10 | 2020-12-01 | 有术肌肤管理(深圳)有限公司 | 一种用于治疗痤疮的化合物及其用于制备药物或化妆品的用途 |
| CN111803652B (zh) * | 2020-08-04 | 2021-09-14 | 南通康是美生物科技有限公司 | 治疗痤疮的化合物在制备治疗痤疮的药物组合物或化妆品组合物中的用途 |
| US12029718B2 (en) | 2021-11-09 | 2024-07-09 | Cct Sciences, Llc | Process for production of essentially pure delta-9-tetrahydrocannabinol |
| TW202532060A (zh) * | 2023-12-01 | 2025-08-16 | 日商Ｅａ製藥股份有限公司 | 醫藥組成物 |
| WO2025115989A1 (ja) * | 2023-12-01 | 2025-06-05 | Ｅａファーマ株式会社 | 医薬組成物 |
| WO2025211248A1 (ja) * | 2024-04-04 | 2025-10-09 | Ｅａファーマ株式会社 | 医薬組成物 |
| WO2026063442A1 (ja) * | 2024-09-18 | 2026-03-26 | Ｅａファーマ株式会社 | 医薬組成物 |
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| AU2014230583B2 (en) * | 2013-03-13 | 2017-09-28 | Takeda Pharmaceutical Company Limited | Guanidinobenzoic acid ester compound |
| SMT202000071T1 (it) | 2013-06-21 | 2020-03-13 | Myokardia Inc | Composti di pirimidinadione contro le condizioni cardiache |
| US9428470B2 (en) | 2014-02-13 | 2016-08-30 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| MX373103B (es) | 2014-02-13 | 2020-04-17 | Incyte Holdings Corp | Ciclopropilaminas como inhibidores de desmetilasa específica de lisina 1 (lsd1). |
| SI3105218T1 (sl) | 2014-02-13 | 2019-11-29 | Incyte Corp | Ciklopropilamini kot inhibitorji LSD1 |
| US9346776B2 (en) | 2014-02-13 | 2016-05-24 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound |
-
2015
- 2015-02-11 US US14/619,489 patent/US9346776B2/en active Active
- 2015-02-12 SM SM20190175T patent/SMT201900175T1/it unknown
- 2015-02-12 TR TR2019/03892T patent/TR201903892T4/tr unknown
- 2015-02-12 PT PT15706546T patent/PT3105213T/pt unknown
- 2015-02-12 AU AU2015216438A patent/AU2015216438B2/en active Active
- 2015-02-12 JO JOP/2015/0028A patent/JO3472B1/ar active
- 2015-02-12 WO PCT/JP2015/000639 patent/WO2015122187A1/en not_active Ceased
- 2015-02-12 ME MEP-2019-89A patent/ME03422B/me unknown
- 2015-02-12 HR HRP20190369TT patent/HRP20190369T1/hr unknown
- 2015-02-12 EA EA201691619A patent/EA032201B1/ru not_active IP Right Cessation
- 2015-02-12 RS RS20190324A patent/RS58498B1/sr unknown
- 2015-02-12 DK DK15706546.7T patent/DK3105213T3/en active
- 2015-02-12 NZ NZ722035A patent/NZ722035A/en unknown
- 2015-02-12 BR BR112016018455-6A patent/BR112016018455B1/pt active IP Right Grant
- 2015-02-12 SI SI201530626T patent/SI3105213T1/sl unknown
- 2015-02-12 MY MYPI2016702925A patent/MY173607A/en unknown
- 2015-02-12 MA MA39246A patent/MA39246A1/fr unknown
- 2015-02-12 JP JP2016550664A patent/JP6383427B2/ja active Active
- 2015-02-12 SG SG11201605654QA patent/SG11201605654QA/en unknown
- 2015-02-12 CA CA2938191A patent/CA2938191C/en active Active
- 2015-02-12 ES ES15706546T patent/ES2717113T3/es active Active
- 2015-02-12 UY UY0001035994A patent/UY35994A/es not_active Application Discontinuation
- 2015-02-12 KR KR1020167025277A patent/KR102378454B1/ko active Active
- 2015-02-12 PL PL15706546T patent/PL3105213T3/pl unknown
- 2015-02-12 CR CR20160367A patent/CR20160367A/es unknown
- 2015-02-12 PE PE2016001239A patent/PE20161243A1/es unknown
- 2015-02-12 HU HUE15706546A patent/HUE042709T2/hu unknown
- 2015-02-12 CN CN201580007800.9A patent/CN105980370B/zh active Active
- 2015-02-12 AR ARP150100411A patent/AR099400A1/es active IP Right Grant
- 2015-02-12 MX MX2016010559A patent/MX368392B/es active IP Right Grant
- 2015-02-12 EP EP15706546.7A patent/EP3105213B1/en active Active
- 2015-02-12 LT LTEP15706546.7T patent/LT3105213T/lt unknown
- 2015-02-12 GE GEAP201714261A patent/GEP20176808B/en unknown
- 2015-02-12 TW TW104104693A patent/TWI669297B/zh active
- 2015-02-12 US US15/117,538 patent/US9969705B2/en active Active
- 2015-12-02 UA UAA201609351A patent/UA118280C2/uk unknown
-
2016
- 2016-07-19 IL IL246838A patent/IL246838B/en active IP Right Grant
- 2016-07-28 CL CL2016001911A patent/CL2016001911A1/es unknown
- 2016-08-10 PH PH12016501582A patent/PH12016501582B1/en unknown
- 2016-08-11 DO DO2016000206A patent/DOP2016000206A/es unknown
- 2016-08-11 EC ECIEPI201667137A patent/ECSP16067137A/es unknown
-
2018
- 2018-08-03 JP JP2018146459A patent/JP6529649B2/ja active Active
-
2019
- 2019-03-27 CY CY20191100356T patent/CY1121534T1/el unknown
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