JPH0721564U - Vial closure - Google Patents

Abstract

(57) [Summary] [Purpose] The top surface of the rubber stopper can be completely aseptically protected, there is no risk of foreign matter as seen in aluminum winding, easy separation and disposal, and opening (EN) Provided is a hermetic closure device for vials, which is easy to check and can be confirmed as unopened. [Structure] The hermetically sealed closure of the present invention comprises a lid 12 on a top surface 13.
And a rubber stopper 2 having a flange 22 that is pressed against the tip of the mouth of the vial V by this cap 5.
With the female coupling means (female screw 16 and locking portion 17) provided on the inner wall of the skirt portion 11, the male coupling means (male screw 31 and annular protrusion 32) provided on the outer wall of the mouth portion of the vial V is formed. It is designed to be permanently attached.

Description

[Detailed description of the device]

[0001]

[Industrial applications]

 The present invention relates to a stopper that closes the mouth of a vial, and more specifically, it completely aseptically protects the top surface of a rubber stopper as compared with the case of a conventional stopper that requires aluminum winding. The present invention relates to a sealing and closing device for a vial, which does not generate a foreign substance as seen when aluminum is wound.

[0002]

[Prior art]

 Conventionally, as shown in FIG. 4, the sealing of the vial mouth is generally performed by an aluminum winding member 103 in which a lid made of synthetic resin which is easily peeled off is attached on a rubber stopper 102 plugged in the mouth 101. Then, the skirt portion 104 of the aluminum winding member 103 is wrapped around the locking flange 105 of the vial opening portion 101. However, the method of tightening with aluminum does not guarantee the sterility of the top surface of the rubber stopper, it is troublesome to remove the aluminum tightening member, and it is troublesome to separate and discard it. There are problems such as easy occurrence.

On the other hand, in order to protect the inside of the bottle from bacteria and other contaminants, as a cap member for hermetically closing the mouth of the bottle, a hermetically sealed stopper and a screw at the mouth of the bottle so as to cover the stopper. There has been proposed a bottle sealing and closing device including a cap to be fitted (Japanese Patent Publication No. 63-40751). However, when using this cap member for a vial, it is necessary to rotate the cap to remove it when exposing the top surface of the rubber stopper, and it is troublesome to attach the cap again after removing the cap. Therefore, it has a drawback that it cannot be confirmed that it has not been opened.

[0004]

[Problems to be solved by the device]

 The present invention has been made in view of the above circumstances, and the top surface of the rubber stopper can be completely aseptically protected, and there is no possibility of generation of foreign matter as seen when aluminum is tightened. It is an object of the present invention to provide a vial hermetically closing and closing tool that is easy to open, easy to open, and can be confirmed to be unopened.

[0005]

[Means for Solving the Problems]

 In order to solve the above problems, the present invention has a female coupling means on the inner wall of the skirt, a through hole is formed on the top surface, and the outside of the through hole is formed on the rubber plug pressing portion. The cap comprises a cap that is non-detachably coupled to the mouth of the vial by the coupling means, and a rubber stopper having a flange that is pressed against the tip of the mouth of the vial by the rubber stopper pressing portion of the cap on the outside of the top surface. A vial sealing and closing tool is used, in which a lid part that can be easily peeled off is attached to the rubber plug pressing part to close the through hole airtightly.

[0006]

[Action]

 According to the above configuration, in the vial as shown in FIG. 2, the sealing closure C and the vial V are irremovably coupled by the engagement of the locking portion 17 and the annular protrusion 32. Then, for example, when the lid 12 is pushed upward with a thumb, the lid 12 is broken from the fragile portion 15 of the top surface 13 and the top surface 23 of the rubber plug 2 is exposed.

[0007]

【Example】

 Next, an embodiment of the present invention will be described with reference to the drawings. 1 is a longitudinal sectional view showing an embodiment of the hermetically closing device of the present invention, FIG. 2 is a view showing a state in which the hermetically closing device shown in FIG. 1 is attached to a vial, and FIG. 3 is another embodiment. FIG. FIG. 4 is a view showing a conventional hermetically-sealing device using an aluminum winding member. As shown in FIGS. 1 and 2, the hermetic closure device of the present invention includes a cap 1 on which a lid 12 is attached to a top surface 13 so that the lid 12 can be easily peeled off, and the cap 5 presses the mouth end of a vial V 1. It is made of a rubber stopper 2 having a flange 22 and is provided on the outer wall of the mouth portion of the vial V by female coupling means (female screw 16 and locking portion 17) provided on the inner wall of the skirt portion 11 of the cap 1. It is adapted to be non-detachably coupled with the provided male coupling means (male screw 31 and annular projection 32).

The cap 1 is usually made of a synthetic resin such as polyethylene, polypropylene, polyester, polyvinyl chloride, ABS resin, or polycarbonate, and includes a skirt portion 11, a top surface 13 and a lid portion 12. The skirt portion 11 is a portion corresponding to the side wall of the cap 1, on the inner wall of which a female screw 16 is provided on the inner side and a locking portion 17 is provided on the lower end as female coupling means, and the male portion of the mouth of the vial V is formed. It is adapted to be coupled with the male screw 31 and the annular protrusion 32 which are coupling means. The locking portion 17 is an annular protrusion or a plurality of protrusions arranged in an annular shape. The top surface 13 side is preferably step-shaped, and the bottom side is step-shaped. Once the cap 1 is attached by engaging with the protrusion 32, it cannot be removed unless it is broken. A through hole 14 is bored in the top surface 13 of the cap 1, and an edge of the outside of the through hole 14 and on the side of the through hole 14 is annularly projected to form an annular projection 18. The top surface 13 outside the through hole 13 including the annular projection 18 constitutes a rubber plug pressing portion 19. The annular protrusion 18 can press the annular groove 21 of the rubber plug 2 to prevent the rubber plug 2 from falling off, and to reliably seal between the top surface 23 of the rubber plug 2 and the cap 1.

The through hole 14 of the cap 1 is airtightly closed by a lid portion 12 which is attached to the rubber plug pressing portion 19 so as to be easily detachable. The lid portion 12 is usually integrally formed of the same material as the skirt portion 11 and the rubber plug pressing portion 19, but is bonded by a method such as heat welding using a material that can be bonded to the material forming the rubber plug pressing portion 19. You may. The lid 12 may be a disc-shaped one as shown in FIG. 1 or a synthetic resin film 120 as shown in FIG. When the lid 12 is attached to the rubber plug pressing portion 19, in the case of the disc-shaped one shown in FIG. 1, the rubber plug pressing portion 19 should be integrally formed at the edge of the through hole 13 of the rubber plug pressing portion 19 via the fragile portion 15. It is preferable to heat-weld to the rubber plug pressing portion 19 in the case of the film 120 as shown in FIG. It is preferable that the lid 12 has an outer diameter larger than that of the skirt 11 so that the lid 12 can be easily broken at the time of use. Further, the outer peripheral surface of the lid 12 is provided with a slip preventing means such as a vertical streak. Good. Reference numeral 121 is a tab for peeling off the film 120, and peeling off of the lid portion 12 is achieved by pushing up the lid portion 12 with, for example, a thumb.

The rubber stopper 2 has a flange 22 that is pressed against the end of the mouth of the vial V by the rubber stopper pressing portion 19 of the cap 1, and is usually made of natural rubber or synthetic rubber such as butyl rubber or isoprene rubber. It is formed. In the case of a freeze-dried preparation, as shown in FIG. 1, it has two legs 24 to be inserted into the mouth of a vial V, and in the case of filling a drug solution, one without legs is used. The top surface 23 of the rubber stopper 2 is formed with a recessed portion 25 that indicates the puncture site of the injection needle in the center, and an annular groove 21 is formed adjacent to the flange 22. The annular protrusion 18 of the rubber plug pressing portion 19 is fitted in, and the flange 22 is fitted in the recess between the annular protrusion 18 of the rubber plug pressing portion 19 and the skirt portion 11.

As shown in FIG. 2, the hermetically closing device C having the above-described structure is attached to a vial V having a male coupling means at its mouth. The male screw 31 and the annular protrusion 32 of the male coupling means are coupled to the female screw 16 and the locking portion 17 of the cap 1, respectively, and cannot be removed unless the cap 1 is broken. In use, if the vial V is held in the hand and the lid 12 of the sealing and closing tool C is pushed upward with, for example, the thumb, the lid 12 is ruptured from the fragile portion 15 of the rubber stopper pressing portion 19 and peeled off from the cap 1. Be done. After removing the lid 12, an injection needle (not shown) is punctured in the recess 25 of the top surface 23 of the rubber stopper 2 and the drug solution (not shown) in the vial V is put in the syringe. You can inhale.

[0012]

【The invention's effect】

 As is clear from what has been described above, by adopting the sealing and closing device of the present invention, the top surface of the rubber stopper does not come into contact with the outside air immediately before use, so that the top surface of the rubber stopper is kept aseptic. The advantages are that the cap can be easily removed, the metal aluminum winding member is not used, so it can be easily separated and discarded, and that no foreign matter such as metal powder generated during aluminum winding is generated. You can

[Brief description of drawings]

FIG. 1 is a vertical cross-sectional view showing an embodiment of the hermetic closure device of the present invention.

FIG. 2 is a view showing a state in which the hermetic closure device shown in FIG. 1 is attached to a vial.

FIG. 3 is a vertical cross-sectional view showing another embodiment of the present invention.

FIG. 4 is a view showing a conventional hermetically closing member using an aluminum winding member.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Cap 11 Skirt part 12 Lid part 15 Fragile part 16 Female screw 17 Locking part 18 Annular protrusion 19 Rubber stopper pressing part 2 Rubber stopper 21 Annular groove 22 Flange C Sealing closure V Vial bottle

Claims (3)

[Scope of utility model registration request] 1. A mouth of a vial by the coupling means, wherein a female coupling means is provided on an inner wall of the skirt portion, a through hole is formed on a top surface, and a rubber stopper pressing portion is formed on the outside of the through hole. A cap that is permanently attached to the cap and a rubber stopper having a flange that is pressed against the tip of the mouth of the vial by the rubber stopper pressing portion of the cap on the outer side of the top surface. A sealed closure for a vial, characterized in that a possible lid is attached to close the through hole airtightly. 2. The hermetic closure device for a vial according to claim 1, wherein the lid is a disk-shaped member attached to the edge portion of the rubber stopper pressing portion on the side of the through hole via the fragile portion. 3. The hermetic closure device for a vial according to claim 1, wherein the lid is a thermoplastic synthetic resin film heat-welded to the rubber stopper pressing portion.