JPS5564797A - Preparation of hypotensive substance - Google Patents

Preparation of hypotensive substance

Info

Publication number
JPS5564797A
JPS5564797A JP13730778A JP13730778A JPS5564797A JP S5564797 A JPS5564797 A JP S5564797A JP 13730778 A JP13730778 A JP 13730778A JP 13730778 A JP13730778 A JP 13730778A JP S5564797 A JPS5564797 A JP S5564797A
Authority
JP
Japan
Prior art keywords
molecular weight
weight fraction
sanitanin
mycelia
liquid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP13730778A
Other languages
Japanese (ja)
Other versions
JPS5717518B2 (en
Inventor
Mitsuharu Sakakida
Tetsuo Ikegawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to JP13730778A priority Critical patent/JPS5564797A/en
Publication of JPS5564797A publication Critical patent/JPS5564797A/en
Publication of JPS5717518B2 publication Critical patent/JPS5717518B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

PURPOSE: To prepare hypotensive substances sanitanin AWD, by culturing mycelia of Themella fuciformis Berk or Volvariella volvacea (Fr.) Sing in a liquid medium, extracting the product, and separating and purifying the extract.
CONSTITUTION: Fruit bodies obtained by treating mycelia of Themella fuciformis Berk (FERM-P No.4450) or Volvariella volvacea (Fr.) Sing (FERM-P No.4393) are cultured in a liquid medium, and the mycelia are separated from the medium, extracted with water or dilute alkali solution, and separated into a high-molecular weight fraction and a low-molecular weight fraction by ultrafiltration. The high- molecular weight fraction is subjected to the fractional precipitation to obtain sanitain A. Sanitanin B is obtained from the low-molecular weight fraction by the similar process. After separating sanitaning C by the fractional precipitation of the cultured liquid, sanitanin D is obtained by the ion exchange resin treatment of the liquid.
USE: Sanitanins have carcinostatic activity as well as hypotensive activity.
COPYRIGHT: (C)1980,JPO&Japio
JP13730778A 1978-11-09 1978-11-09 Preparation of hypotensive substance Granted JPS5564797A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP13730778A JPS5564797A (en) 1978-11-09 1978-11-09 Preparation of hypotensive substance

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13730778A JPS5564797A (en) 1978-11-09 1978-11-09 Preparation of hypotensive substance

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP56103280A Division JPS5826958B2 (en) 1981-07-03 1981-07-03 Manufacturing method for hypotensive substances

Publications (2)

Publication Number Publication Date
JPS5564797A true JPS5564797A (en) 1980-05-15
JPS5717518B2 JPS5717518B2 (en) 1982-04-10

Family

ID=15195615

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13730778A Granted JPS5564797A (en) 1978-11-09 1978-11-09 Preparation of hypotensive substance

Country Status (1)

Country Link
JP (1) JPS5564797A (en)

Also Published As

Publication number Publication date
JPS5717518B2 (en) 1982-04-10

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