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Fujimoto Pharmaceutical Corp
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Fujimoto Pharmaceutical Corp
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Application filed by Fujimoto Pharmaceutical CorpfiledCriticalFujimoto Pharmaceutical Corp
Priority to JP9433180ApriorityCriticalpatent/JPS5718676A/en
Publication of JPS5718676ApublicationCriticalpatent/JPS5718676A/en
NEW MATERIAL:A 4-isopropyl-6-(1H-indol-4-yloxy)methyl-morpholino-2,3-dione expressed by formula I.
USE: Various specific pharmacological effects of adrenergic β-receptor blocking action are expected.
PROCESS: 4-[2-Hydroxy-3-(isopropylamino)-propoxy]-indole expressed by formula II known as a useful chemical pindolol is reacted with an oxalic acid derivative expressed by formula III (R is Cl, Br or lower alkoxyl) in the absence or presence of an inert solvent at 50W130°C within one hour to give the compound expressed by formula I.
COPYRIGHT: (C)1982,JPO&Japio
JP9433180A1980-07-091980-07-09Novel indole derivative and its preparation
PendingJPS5718676A
(en)