JPS58501074A - アルカロイド化合物 - Google Patents

アルカロイド化合物

Info

Publication number
JPS58501074A
JPS58501074A JP57502047A JP50204782A JPS58501074A JP S58501074 A JPS58501074 A JP S58501074A JP 57502047 A JP57502047 A JP 57502047A JP 50204782 A JP50204782 A JP 50204782A JP S58501074 A JPS58501074 A JP S58501074A
Authority
JP
Japan
Prior art keywords
cancer
alkaloid
preparation
acid
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57502047A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0326199B2 (2
Inventor
ノビツキ−・バツシル
Original Assignee
ノビツキ−，バツシル
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ノビツキ−，バツシル filed Critical ノビツキ−，バツシル
Publication of JPS58501074A publication Critical patent/JPS58501074A/ja
Publication of JPH0326199B2 publication Critical patent/JPH0326199B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/041—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/224—Phosphorus triamides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/564—Three-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Filling Or Discharging Of Gas Storage Vessels (AREA)
JP57502047A 1981-07-13 1982-07-08 アルカロイド化合物 Granted JPS58501074A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3128018.8 1981-07-13
DE19813128018 DE3128018A1 (de) 1981-07-13 1981-07-13 "verfahren zum diagnostizieren und fuer die therapeutische behandlung von tumoren und/oder infektioesen krankheiten verschiedenster art unter praeparativem einsatz von alkaloid-verbindungen bzw. deren salze"

Publications (2)

Publication Number Publication Date
JPS58501074A true JPS58501074A (ja) 1983-07-07
JPH0326199B2 JPH0326199B2 (2) 1991-04-10

Family

ID=6136994

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57502047A Granted JPS58501074A (ja) 1981-07-13 1982-07-08 アルカロイド化合物

Country Status (10)

Country Link
EP (1) EP0083600B1 (2)
JP (1) JPS58501074A (2)
AU (1) AU568483B2 (2)
DE (3) DE3128018A1 (2)
DK (1) DK33283D0 (2)
FI (1) FI73131C (2)
GB (1) GB2110533B (2)
WO (1) WO1983000486A1 (2)
YU (1) YU44969B (2)
ZA (1) ZA824983B (2)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005509006A (ja) * 2001-11-15 2005-04-07 ノヴィッキイ、 ヴァジル アルカロイドを反応させる製造方法および反応生成物の薬剤調製の使用
JP2012510490A (ja) * 2008-12-01 2012-05-10 ウニベルジテ・ボルドー・セガラン ビス［ｏ−（１４−ベンゾイルアコニン−８−イル）］エステル

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623504B1 (fr) * 1987-11-25 1990-03-09 Adir Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
AT407833B (de) * 1995-06-01 2001-06-25 Nowicky Wassyl Dr Mittel zur behandlung von strahlenschäden
HUP9601096A2 (hu) * 1996-04-26 1998-01-28 János Aradi Anti-HIV-aktivitással rendelkező gyógynövényalapú gyógyászati és gyógyhatású készítmény,és vegyületek
WO1999008528A1 (en) 1997-08-19 1999-02-25 Emory University Noscapine derivatives, useful as anticancer agents
US6673814B2 (en) 1997-08-19 2004-01-06 Emory University Delivery systems and methods for noscapine and noscapine derivatives, useful as anticancer agents
AT408719B (de) * 2000-03-22 2002-02-25 Nowicky Wassili Mittel zur behandlung von hepatitis c
US6426351B1 (en) * 2000-08-11 2002-07-30 Dana-Farber Cancer, Inc. Chelerythrine-based therapies for cancer
DE10043615A1 (de) * 2000-09-05 2002-03-14 Erich Schneider Freikolbenmotor mit rotativer Bewegungs- und Energieauskopplung
EP1459753A1 (en) 2003-03-18 2004-09-22 Nowicky, Wassyl, Dipl.-Ing. DDr. Quaternary chelidonine and alkaloid derivatives, process for their preparation and their use in the manufacture of medicaments
WO2006053649A1 (en) * 2004-11-19 2006-05-26 Nowicky Wassili Method for the detection of cancer
WO2006053680A1 (en) * 2004-11-19 2006-05-26 Nowicky Wassili Ex vivo cancer diagnostic method
WO2007073919A2 (en) * 2005-12-28 2007-07-05 Nowicky Wassili Method and kit for the detection of cancer
RU2304584C1 (ru) * 2006-05-12 2007-08-20 Иващенко Андрей Александрович Производные носкапина (варианты), комбинаторная и фокусированная библиотеки, фармацевтическая композиция, способы их получения (варианты) и применения
WO2015144900A1 (de) * 2014-03-27 2015-10-01 Nowicky Wassili Diagnoseverfahren zur krebsfrüherkennung

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4994823A (2) * 1973-01-24 1974-09-09
US3865830A (en) * 1969-06-16 1975-02-11 Nikolai Mikhailovich Turkevich Thiophosphamide derivatives of isoquinoline alkaloids, method of producing and application thereof
JPS5341415A (en) * 1976-06-28 1978-04-14 Nowicky Wassili Preparation of novel antitumor agent
EP0654644A1 (de) * 1993-11-22 1995-05-24 EISENMANN MASCHINENBAU KG (Komplementär: EISENMANN-Stiftung) Verfahren und Anordnung zum Brennen von Keramik o. dgl. Brenngut

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT354644B (de) * 1975-12-19 1980-01-25 Nowicky Wassili Verfahren zur herstellung von neuen salzen von alkaloidderivaten von thiophosphorsaeure

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3865830A (en) * 1969-06-16 1975-02-11 Nikolai Mikhailovich Turkevich Thiophosphamide derivatives of isoquinoline alkaloids, method of producing and application thereof
JPS4994823A (2) * 1973-01-24 1974-09-09
JPS5341415A (en) * 1976-06-28 1978-04-14 Nowicky Wassili Preparation of novel antitumor agent
EP0654644A1 (de) * 1993-11-22 1995-05-24 EISENMANN MASCHINENBAU KG (Komplementär: EISENMANN-Stiftung) Verfahren und Anordnung zum Brennen von Keramik o. dgl. Brenngut

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005509006A (ja) * 2001-11-15 2005-04-07 ノヴィッキイ、 ヴァジル アルカロイドを反応させる製造方法および反応生成物の薬剤調製の使用
JP2012510490A (ja) * 2008-12-01 2012-05-10 ウニベルジテ・ボルドー・セガラン ビス［ｏ−（１４−ベンゾイルアコニン−８−イル）］エステル

Also Published As

Publication number Publication date
FI73131C (fi) 1987-09-10
YU44969B (en) 1991-06-30
YU152982A (en) 1986-04-30
WO1983000486A1 (fr) 1983-02-17
ZA824983B (en) 1984-04-25
DE3248943D2 (en) 1984-10-04
EP0083600A1 (de) 1983-07-20
EP0083600B1 (de) 1987-11-25
FI830760L (fi) 1983-03-07
FI73131B (fi) 1987-05-29
DE3128018A1 (de) 1983-04-07
JPH0326199B2 (2) 1991-04-10
GB2110533A (en) 1983-06-22
GB2110533B (en) 1986-06-11
DK33283D0 (2) 1983-01-28
FI830760A0 (fi) 1983-03-07
AU8681482A (en) 1983-02-22
DE3277726D1 (en) 1988-01-07
AU568483B2 (en) 1988-01-07

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