JPS6222967B2 - - Google Patents

Info

Publication number
JPS6222967B2
JPS6222967B2 JP52112093A JP11209377A JPS6222967B2 JP S6222967 B2 JPS6222967 B2 JP S6222967B2 JP 52112093 A JP52112093 A JP 52112093A JP 11209377 A JP11209377 A JP 11209377A JP S6222967 B2 JPS6222967 B2 JP S6222967B2
Authority
JP
Japan
Prior art keywords
cymetidine
strong
methyl
histamine
peak
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP52112093A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5340771A (en
Inventor
Mikaeru Gai Babin Patoritsuku
Kurisutofuaa Fuiritsupusu Surei Jeimuzu
Deibitsudo Tobei Jofurii
Jon Uoodo Richaado
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GSK PLC
Original Assignee
GlaxoSmithKline PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB3906576A external-priority patent/GB1543238A/en
Application filed by GlaxoSmithKline PLC filed Critical GlaxoSmithKline PLC
Publication of JPS5340771A publication Critical patent/JPS5340771A/ja
Publication of JPS6222967B2 publication Critical patent/JPS6222967B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP11209377A 1976-09-21 1977-09-16 Novel polymorph of heterocyclic compound Granted JPS5340771A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3906576A GB1543238A (en) 1976-09-21 1976-09-21 Polymorph of cimetidine
GB271677 1977-01-24

Publications (2)

Publication Number Publication Date
JPS5340771A JPS5340771A (en) 1978-04-13
JPS6222967B2 true JPS6222967B2 (pl) 1987-05-20

Family

ID=26237687

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11209377A Granted JPS5340771A (en) 1976-09-21 1977-09-16 Novel polymorph of heterocyclic compound

Country Status (10)

Country Link
JP (1) JPS5340771A (pl)
AU (1) AU510629B2 (pl)
BE (1) BE858432A (pl)
CA (1) CA1096387A (pl)
DE (1) DE2742531A1 (pl)
FR (1) FR2364906A1 (pl)
IE (1) IE45873B1 (pl)
IL (1) IL52784A (pl)
LU (1) LU78142A1 (pl)
NZ (1) NZ184893A (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56104868A (en) * 1980-01-24 1981-08-20 Fujimoto Seiyaku Kk Conversion between polymorphous crystals of cimetidine
JPS56164122A (en) * 1980-05-21 1981-12-17 Fujimoto Seiyaku Kk Drug composition comprising cimetidine as main agent
HU185636B (en) * 1981-06-26 1985-03-28 Richter Gedeon Vegyeszet Process for preparing new cimetidine-hydrate /cimetidine-h/
HU185457B (en) * 1981-09-25 1985-02-28 Richter Gedeon Vegyeszet Process for preparating cimetidine-z
JPS5888366A (ja) * 1981-11-19 1983-05-26 Fujimoto Seiyaku Kk グアニジン誘導体の製造法
JPS59128375A (ja) * 1983-01-10 1984-07-24 Tokawa Tetsuo イミダゾ−ル系化合物の製法
JPS59130274A (ja) * 1983-01-14 1984-07-26 Tokawa Tetsuo イミダゾ−ル系化合物の製法
JPS59130273A (ja) * 1983-01-14 1984-07-26 Tokawa Tetsuo イミダゾ−ル系化合物の製造法
HU196184B (en) * 1986-09-11 1988-10-28 Richter Gedeon Vegyeszet Process for producing cimetidine-a modification

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1397436A (en) * 1972-09-05 1975-06-11 Smith Kline French Lab Heterocyclic n-cyanoguinidines
GB1531231A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for the production of cyanoguanidine derivatives
GB1533380A (en) * 1974-09-02 1978-11-22 Smith Kline French Lab Process for the preparation of heterocyclic substituted thioureas and h-cyanoguanidines
PT65369B (en) * 1975-08-20 1978-01-10 Smithkline Corp Reduction process

Also Published As

Publication number Publication date
IL52784A0 (en) 1977-10-31
JPS5340771A (en) 1978-04-13
AU2879277A (en) 1979-03-22
LU78142A1 (pl) 1978-01-17
IE45873L (en) 1978-07-24
CA1096387A (en) 1981-02-24
NZ184893A (en) 1980-11-28
AU510629B2 (en) 1980-07-03
IL52784A (en) 1980-09-16
FR2364906A1 (fr) 1978-04-14
IE45873B1 (en) 1982-12-15
BE858432A (fr) 1978-03-06
DE2742531A1 (de) 1978-03-23

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