JPS6248501B2 - - Google Patents

Description

[Detailed description of the invention]

The present invention relates to packaging for dental filling materials with excellent storage stability. Conventionally, dental filling materials have been supplied to dentists in the form of two-part packaging (polymerizable monomer/filler/initiator system and polymerizable monomer/filler/activator system). Since the polymerizable monomer coexists with an initiator or an activator in each package, its storage stability becomes an issue. For this reason, JP-A-48-
In No. 62291, a shallow dish-shaped container made of polyethylene, polypropylene, etc. is filled with a filler material to a thin filling thickness, leaving a space at the top. However, even with this, the storability was still insufficient; for example, with a filling thickness of 6 mm, it could only withstand storage at room temperature for about 12 months. Therefore, the need for improvement was recognized. The inventors of the present invention have conducted extensive studies on this problem, and have found that, unexpectedly, by making the thickness of the container in contact with the filling material very thin, the storage stability of the filling material is significantly improved. The present invention was developed based on this recognition. That is, the present invention provides (i)
A dental filling material consisting of a polymerizable monomer, (ii) a filler, and (iii) an initiator or activator, which is filled into a container in which the contacting portion of the dental material is made of plastic. In the packaging, the dental filling material is filled into the container to a thickness of 9 mm or less, the top surface of the filling material is in contact with air, the bottom surface is in contact with the bottom plate of the container, which has a thickness of 0.8 mm or less, and , the dental filling material has a plate thickness of 0.8 mm in 50% or more of the total area where the filling material contacts the container.
This is a packaging for a dental filling material that has excellent storage stability and is characterized by being in contact with the following bottom plate. In the present invention, a paste containing a polymerizable monomer, filler, and an initiator as main components or a paste containing a polymerizable monomer, filler, and activator as main components is enclosed in one package of dental filling material. . Such materials are already known and both pastes are supplied to dentists as a set (in two-pack form). Among the (meth)acrylic monomers, the skeleton of bisphenol A is used as a polymerizable monomer.

A di(meth)acrylate monomer having the formula (for example, Bis-
GMA, bisphenol A dimethacrylate, etc.) are used. Since Bis-GMA is highly viscous, it is usually not used alone, but rather diluted with methyl methacrylate, triethylene glycol dimethacrylate, tetraethylene glycol dimethacrylate, etc. As the filler, fine inorganic materials such as colloidal silica, fused silica, aluminum oxide, various ceramics, and crystalline quartz with a particle size of 100 μm or less are used. Usually, inorganic fillers are treated with silane. Filler is a component that imparts mechanical properties to the cured material when the dental filling material is filled into a tooth and hardened, and is the main component of the dental filling material. Therefore, in dental filling materials, the filler is 50% higher than the polymerizable monomer + filler.
It accounts for more than 65% by weight, preferably 65 to 80% by weight.
Various known initiators and activators can be used, but preferably diacyl peroxide (e.g. benzoyl peroxide) is used as the initiator and aromatic secondary or tertiary amine (e.g. N, N-diethanol-P-toluidine). In addition, colorants, dispersion stabilizers, ultraviolet absorbers, antioxidants, etc. may be added as necessary. These ingredients are kneaded into a paste by a conventional method and filled into a container. In order to preserve the filling material, the container used in the present invention must have a portion made of plastic that comes into contact with the dental filling material. The material for such a container is disclosed in the above-mentioned Japanese Patent Application Laid-Open No. 48-62291.
Disclosed in the issue. As specific materials, polyethylene, polypropylene, polyvinyl chloride, and polycarbonate described in the above-mentioned documents are also used in the present invention. Among these, containers made of polypropylene are preferred. The container is composed of a lid and a main body, but the lid and the main body need not be made of the same material, as long as the portion in contact with the filling material is made of the above-mentioned plastic. Since the container is preferably light-opaque, the container is molded by mixing a coloring agent with the above-mentioned material. One embodiment of the container used in the present invention is shown in FIGS. 1 to 4. FIG. 1 is a schematic view of the lid, and FIG. 2 is a schematic view of the body of the container. The body and lid are engaged by screws as shown. The pasty filling material is filled in a thin layer into the dish-shaped body of the container. In the present invention, it is necessary that the thickness of the layer of filler material be 9 mm or less. If it is thicker than this, the filling material tends to harden, resulting in decreased storage stability. To ensure storage stability, the filling material must be filled to less than 1/2 of the depth of the container so that the top surface of the filling material is in contact with the air, and an air layer is formed in the upper layer of the container. It is preferable. A feature of the present invention is that the thickness of the bottom plate of the container in contact with the filling material is 0.8 mm or less (preferably,
The goal is to make it extremely thin (0.2 to 0.6 mm). Conventional products have a thickness of at least 1.1 mm.
By doing so, the storage stability of the filling material can be greatly improved, and when stored at room temperature, the filling material can be stored stably for more than 2 years (conventional products can be stored for about 12 months). ). In the present invention, the main body of the container is supported on a table by side plates 3, and the bottom plate 1 in contact with the filling material is slightly raised on the opposite side so as to be in contact with the air, as shown in FIG. Preferably. Further, it is desirable that a support portion 2 is provided to reinforce the thin bottom plate. The number, shape, etc. of the supporting parts are selected as appropriate. (Six pieces are provided in Fig. 4.) In the present invention, it is not necessary that the plate thickness be 0.8 mm or less over the entire surface of the container that comes in contact with the dental filling material (including the side surfaces). do not have. However, the filling material has more than 50% of the contact area
It must be in contact with a bottom plate with a thickness of 0.8 mm or less.
Necessary for preservation. In the present invention, the bottom plate is preferably formed so that substantially the entire surface, excluding the supporting portion, has a thickness of 0.8 mm or less. Such containers are manufactured by known plastic molding methods. As described above, by filling a plastic container with a paste-like filling material to a thickness of 9 mm or less, the upper surface is in contact with air and the lower surface is in contact with a bottom plate with a thickness of 0.8 mm or less. , it was possible to greatly improve the storage stability of the filling material. The present invention will be explained in more detail with reference to Examples below, but the present invention is not limited thereto. Examples Paste-like dental filling materials M agent and N agent consisting of the following components were prepared. The M agent and the N agent are mixed in equal amounts (volumes) and used when filling a tooth. M agent Bis-GMA 16.9 parts by weight triethylene glycol dimethacrylate
5.7 Benzoyl peroxide 0.4 2,6-di-t-butyl-P-cresol 0.04 Silanized quartz powder 75.2 Colloidal silica (Aerosil 380, manufactured by Nippon Aerosil) 1.8 N agent Bis-GMA 18.1 parts by weight Triethylene glycol Dimethacrylate
6.0 N,N-diethanol-P-toluidine
0.2 parts by weight 2-hydroxy-3-methoxybenzophenone
0.2 Hydroquinone monomethyl ether 0.03 Silanized quartz powder 74.1 Colloidal silica (same as above) 1.4 Polypropylene containers (shallow cylindrical, inner diameter 45 mm, (shown in Figures 1 to 4) was prepared, and the above-mentioned filling materials M agent and N agent were added to 5.5 mm.
(the bottom portion occupies approximately 65% of the total area in contact with the filling material). Then, it was stored at a high temperature (45°C) and the curing time was measured. The results are shown in Table 1.

[Table] From the results in Table 1, it is recognized that the thickness of the bottom of the container that comes into contact with the paste has a large effect on the curing time, and that it is effective to reduce the thickness of the bottom to 0.8 mm or less. confirmed.

[Brief explanation of the drawing]

Figures 1, 2, 3 and 4 show one embodiment of the container used in the present invention.
The figure is a schematic diagram of the lid part, the second figure is a schematic diagram of the main body part, the third figure is a sectional view of the side of the main body part, and the fourth figure is a schematic diagram of the main body part.
The figure is a rear view of the main body. 1... Bottom plate of the container, 2... Support part, 3... Side surface of the container.

Claims (1)

[Claims] 1. A dental filling material consisting of (i) a polymerizable monomer, (ii) a filler, and (iii) an initiator or activator is filled into a container in which the contacting portion of the dental filling material is made of plastic. In the packaging of the dental filling material, the dental filling material is filled into the container to a thickness of 9 mm or less, the upper surface of the filling material is in contact with air, and the lower surface is in contact with the container with a thickness of 0.8 mm or less. Storage stability characterized in that the dental filling material is in contact with the bottom plate and has a thickness of 0.8 mm or less in a portion of 50% or more of the total area where the filling material contacts the container. Superior dental filling material packaging.