JPWO2013150902A1 - 非天然型塩基を含むオリゴデオキシヌクレオチドの切断による５’末端リン酸化オリゴデオキシヌクレオチドの製造方法 - Google Patents

非天然型塩基を含むオリゴデオキシヌクレオチドの切断による５’末端リン酸化オリゴデオキシヌクレオチドの製造方法 Download PDF

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JPWO2013150902A1
JPWO2013150902A1 JP2014509104A JP2014509104A JPWO2013150902A1 JP WO2013150902 A1 JPWO2013150902 A1 JP WO2013150902A1 JP 2014509104 A JP2014509104 A JP 2014509104A JP 2014509104 A JP2014509104 A JP 2014509104A JP WO2013150902 A1 JPWO2013150902 A1 JP WO2013150902A1
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dna
oligodeoxynucleotide
reaction
substituted
unsubstituted
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Japanese (ja)
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泰己 上田
泰己 上田
修司 池田
修司 池田
一貴 田井中
一貴 田井中
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RIKEN
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RIKEN
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/073—Pyrimidine radicals with 2-deoxyribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/173—Purine radicals with 2-deoxyribosyl as the saccharide radical

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2014509104A 2012-04-02 2013-03-22 非天然型塩基を含むオリゴデオキシヌクレオチドの切断による５’末端リン酸化オリゴデオキシヌクレオチドの製造方法 Pending JPWO2013150902A1 (ja)

Priority Applications (1)

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JP2014509104A JPWO2013150902A1 (ja) 2012-04-02 2013-03-22 非天然型塩基を含むオリゴデオキシヌクレオチドの切断による５’末端リン酸化オリゴデオキシヌクレオチドの製造方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012084249 2012-04-02
JP2012084249 2012-04-02
JP2014509104A JPWO2013150902A1 (ja) 2012-04-02 2013-03-22 非天然型塩基を含むオリゴデオキシヌクレオチドの切断による５’末端リン酸化オリゴデオキシヌクレオチドの製造方法

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JPWO2013150902A1 true JPWO2013150902A1 (ja) 2015-12-17

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JP2014509104A Pending JPWO2013150902A1 (ja) 2012-04-02 2013-03-22 非天然型塩基を含むオリゴデオキシヌクレオチドの切断による５’末端リン酸化オリゴデオキシヌクレオチドの製造方法

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JP (1) JPWO2013150902A1 (fr)
WO (1) WO2013150902A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4372091A3 (fr) 2014-12-12 2024-07-31 Tod M. Woolf Compositions et procédés d'édition d'acides nucléiques dans des cellules à l'aide d'oligonucléotides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972618A (en) * 1997-08-28 1999-10-26 Bloch; Will Detection of mutations in nucleic acids by chemical cleavage
US7057026B2 (en) * 2001-12-04 2006-06-06 Solexa Limited Labelled nucleotides
CA2486283A1 (fr) * 2002-05-17 2004-02-05 Nugen Technologies, Inc. Procedes de fragmentation, d'etiquetage et d'immobilisation d'acides nucleiques

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