KR910019952A - 에이코사펜타엔산과 그 에스테르의 분리정제 방법 - Google Patents
에이코사펜타엔산과 그 에스테르의 분리정제 방법 Download PDFInfo
- Publication number
- KR910019952A KR910019952A KR1019900007747A KR900007747A KR910019952A KR 910019952 A KR910019952 A KR 910019952A KR 1019900007747 A KR1019900007747 A KR 1019900007747A KR 900007747 A KR900007747 A KR 900007747A KR 910019952 A KR910019952 A KR 910019952A
- Authority
- KR
- South Korea
- Prior art keywords
- eicosapentaenoic acid
- separation
- carbon atoms
- purification method
- ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 title claims 5
- 229960005135 eicosapentaenoic acid Drugs 0.000 title claims 5
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 title claims 5
- 235000020673 eicosapentaenoic acid Nutrition 0.000 title claims 5
- 238000000034 method Methods 0.000 title claims 4
- 150000002148 esters Chemical class 0.000 title claims 3
- 238000000746 purification Methods 0.000 title claims 3
- 238000000926 separation method Methods 0.000 title claims 3
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical group O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 4
- 125000004432 carbon atom Chemical group C* 0.000 claims 3
- 239000000945 filler Substances 0.000 claims 2
- 239000000377 silicon dioxide Substances 0.000 claims 2
- 150000001298 alcohols Chemical class 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 235000014113 dietary fatty acids Nutrition 0.000 claims 1
- 239000003480 eluent Substances 0.000 claims 1
- 239000000194 fatty acid Substances 0.000 claims 1
- 229930195729 fatty acid Natural products 0.000 claims 1
- 238000004811 liquid chromatography Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 239000007788 liquid Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/03—Monocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C7/00—Purification; Separation; Use of additives
- C07C7/12—Purification; Separation; Use of additives by adsorption, i.e. purification or separation of hydrocarbons with the aid of solids, e.g. with ion-exchangers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Water Supply & Treatment (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fats And Perfumes (AREA)
Abstract
Description
Claims (3)
- 에이코사펜타엔산을 함유하고 있는 지방산 알킬에스테르 혼합물로부터 액체크로마토그라피에 의해 에이코사펜타엔산을 분리 정제함에 있어서, 칼럼충전제로서 8~24개의 탄소수를 가진 알킬리가 실리카에 화학 결합된 것을 사용하고, 용리액으로서 극성 단일 용매를 사용하여서 됨을 특징으로 하는 에이코사펜타엔산과 그 에스테르의 분리정제 방법
- 제1항에 있어서, 상기 탄소수8~28개의 알킬기는 상기 충전재 전체에 대해 5~30중량%로 실리카에 화학 결합되어 있은 것을 특징으로 하는 에이코사펜타엔산과 그 에스테르의 분리정제 방법
- 제1항에 있어서, 상기 극성단일 용매로서는 탄소수1~4개의 저급 알코올을 사용하는 것을 특징으로 하는 에이코사펜타엔산과 그 에스테르의 분리정제 방법※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019900007747A KR920003777B1 (ko) | 1990-05-29 | 1990-05-29 | 에이코사펜타엔산과 그 에스테르의 분리정제 방법 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019900007747A KR920003777B1 (ko) | 1990-05-29 | 1990-05-29 | 에이코사펜타엔산과 그 에스테르의 분리정제 방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR910019952A true KR910019952A (ko) | 1991-12-19 |
| KR920003777B1 KR920003777B1 (ko) | 1992-05-14 |
Family
ID=19299505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019900007747A Expired KR920003777B1 (ko) | 1990-05-29 | 1990-05-29 | 에이코사펜타엔산과 그 에스테르의 분리정제 방법 |
Country Status (1)
| Country | Link |
|---|---|
| KR (1) | KR920003777B1 (ko) |
-
1990
- 1990-05-29 KR KR1019900007747A patent/KR920003777B1/ko not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| KR920003777B1 (ko) | 1992-05-14 |
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| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19900529 |
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| PA0201 | Request for examination |
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| PG1501 | Laying open of application | ||
| G160 | Decision to publish patent application | ||
| PG1605 | Publication of application before grant of patent |
Comment text: Decision on Publication of Application Patent event code: PG16051S01I Patent event date: 19920413 |
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| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 19920806 |
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| GRNT | Written decision to grant | ||
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