LT3312195T - Nebaigtinės osteogenezės gydymo būdai - Google Patents

Nebaigtinės osteogenezės gydymo būdai

Info

Publication number
LT3312195T
LT3312195T LTEP17206987.4T LT17206987T LT3312195T LT 3312195 T LT3312195 T LT 3312195T LT 17206987 T LT17206987 T LT 17206987T LT 3312195 T LT3312195 T LT 3312195T
Authority
LT
Lithuania
Prior art keywords
osteogenesis
infinite
treatment
methods
infinite osteogenesis
Prior art date
Application number
LTEP17206987.4T
Other languages
English (en)
Inventor
Brendan Lee
Kuber Sampath
Original Assignee
Genzyme Corporation
Baylor College Of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50483613&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT3312195(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genzyme Corporation, Baylor College Of Medicine filed Critical Genzyme Corporation
Publication of LT3312195T publication Critical patent/LT3312195T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/42Phosphorus; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515Complete light chain, i.e. VL + CL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
LTEP17206987.4T 2013-03-20 2014-03-20 Nebaigtinės osteogenezės gydymo būdai LT3312195T (lt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361803647P 2013-03-20 2013-03-20
US201361875399P 2013-09-09 2013-09-09
US201361883151P 2013-09-26 2013-09-26

Publications (1)

Publication Number Publication Date
LT3312195T true LT3312195T (lt) 2020-01-10

Family

ID=50483613

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP17206987.4T LT3312195T (lt) 2013-03-20 2014-03-20 Nebaigtinės osteogenezės gydymo būdai
LTEP14717386.8T LT2976359T (lt) 2013-03-20 2014-03-20 Nebaigtinės osteogenezės gydymo būdai

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTEP14717386.8T LT2976359T (lt) 2013-03-20 2014-03-20 Nebaigtinės osteogenezės gydymo būdai

Country Status (26)

Country Link
US (4) US9598486B2 (lt)
EP (3) EP3312195B1 (lt)
JP (3) JP6483086B2 (lt)
KR (1) KR102257138B1 (lt)
CN (2) CN105229028B (lt)
AU (1) AU2014235933B2 (lt)
CA (1) CA2907422C (lt)
CL (1) CL2015002801A1 (lt)
DK (2) DK3312195T3 (lt)
EA (1) EA032327B1 (lt)
ES (2) ES2700238T5 (lt)
HR (2) HRP20181939T4 (lt)
HU (1) HUE046702T2 (lt)
IL (2) IL241461B (lt)
LT (2) LT3312195T (lt)
MX (2) MX389759B (lt)
MY (1) MY172324A (lt)
PH (2) PH12015501864A1 (lt)
PL (2) PL3312195T3 (lt)
PT (2) PT3312195T (lt)
RS (2) RS58188B2 (lt)
SG (2) SG11201506683XA (lt)
SI (2) SI2976359T2 (lt)
TW (1) TWI629995B (lt)
UY (1) UY35493A (lt)
WO (1) WO2014153435A1 (lt)

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HUE046702T2 (hu) * 2013-03-20 2020-03-30 Genzyme Corp Eljárások üvegcsontbetegség kezelésére
TWI726870B (zh) 2015-03-04 2021-05-11 美商健臻公司 具有高親和性、結合性及專一性之結合轉形生長因子-β1的scFv-Fc二聚體
TWI733661B (zh) * 2015-03-04 2021-07-21 美商健臻公司 以高親合性、結合性及特異性結合轉化生長因子-β1的經修飾IgG抗體
JP2019533003A (ja) * 2016-08-11 2019-11-14 プレシセラ,インコーポレイテッド TGF−βアンタゴニストコンジュゲート
CN106755395B (zh) * 2016-12-16 2020-05-12 山东第一医科大学(山东省医学科学院) Xi型成骨不全致病基因fkbp10的突变位点及其应用
EP3571227A1 (en) * 2017-01-20 2019-11-27 Sanofi Anti-tgf-beta antibodies and their use
TWI788321B (zh) * 2017-01-20 2023-01-01 美商健臻公司 骨靶向抗體
TW202506185A (zh) * 2017-01-20 2025-02-16 法商賽諾菲公司 抗TGF-β抗體及其用途
AR110904A1 (es) * 2017-01-20 2019-05-15 Sanofi Sa ANTICUERPOS ANTI-TGF-b Y SU USO
WO2019113123A1 (en) * 2017-12-04 2019-06-13 Precithera, Inc. TGF-ß RECEPTOR FUSION PROTEINS AND OTHER TGF-ß ANTAGONISTS FOR REDUCING TGF-ß SIGNALING
TW202019962A (zh) 2018-07-10 2020-06-01 法商賽諾菲公司 標靶CD38及TGF-β的組合療法
MY204234A (en) 2018-08-27 2024-08-16 Regeneron Pharma Use of raman spectroscopy in downstream purification
CN110916855A (zh) * 2018-09-20 2020-03-27 天津正天医疗器械有限公司 一种仿生多孔椎间植入物及其制造方法
KR20230112629A (ko) * 2020-10-23 2023-07-27 에이치큐 한 종양괴사인자-알파 및 형질전환성장인자-베타의 이작용성 길항제 및 이의 용도
IL308175A (en) * 2021-05-07 2023-12-01 Baylor College Medicine Treatment of moderate to severe defective bone formation
CN113501879B (zh) * 2021-06-30 2022-09-06 拜盖特生物科技(上海)有限公司 一种解除肿瘤免疫微环境中免疫抑制的双功能抗体及其应用和制备方法
US20230144192A1 (en) * 2021-11-01 2023-05-11 Genzyme Corporation Treatment of osteogenesis imperfecta
JP2026502549A (ja) * 2023-01-13 2026-01-23 シャンハイ・カイジン・バイオテクノロジー,リミテッド 多重特異性ポリペプチド複合体
CN120290673A (zh) * 2025-04-02 2025-07-11 湖北省农业科学院农产品加工与核农技术研究所 一种抗光老化胶原多肽的制备方法和应用

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US7368111B2 (en) * 1995-10-06 2008-05-06 Cambridge Antibody Technology Limited Human antibodies specific for TGFβ2
DE19742706B4 (de) 1997-09-26 2013-07-25 Pieris Proteolab Ag Lipocalinmuteine
AU1525700A (en) * 1998-11-19 2000-06-05 Board Of Trustees Of The University Of Arkansas, The Increasing bone strength with selected bisphosphonates
US20040009535A1 (en) * 1998-11-27 2004-01-15 Celltech R&D, Inc. Compositions and methods for increasing bone mineralization
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US6492497B1 (en) * 1999-04-30 2002-12-10 Cambridge Antibody Technology Limited Specific binding members for TGFbeta1
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TWI489993B (zh) * 2007-10-12 2015-07-01 Novartis Ag 骨硬化素(sclerostin)抗體組合物及使用方法
CN101932603A (zh) * 2008-01-15 2010-12-29 卡罗拜奥斯制药公司 使用gm-csf拮抗剂治疗骨质流失病症的方法
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HUE046702T2 (hu) * 2013-03-20 2020-03-30 Genzyme Corp Eljárások üvegcsontbetegség kezelésére

Also Published As

Publication number Publication date
KR102257138B1 (ko) 2021-05-26
DK2976359T3 (da) 2019-01-02
HRP20181939T1 (hr) 2019-01-25
CN105229028A (zh) 2016-01-06
EP2976359B2 (en) 2022-03-23
US20220195025A1 (en) 2022-06-23
SI2976359T1 (sl) 2019-03-29
IL287915A (en) 2022-01-01
EP3312195A1 (en) 2018-04-25
JP2016519093A (ja) 2016-06-30
HRP20192277T1 (hr) 2020-03-06
WO2014153435A1 (en) 2014-09-25
SG10201701985YA (en) 2017-04-27
ES2763869T3 (es) 2020-06-01
TW201524515A (zh) 2015-07-01
EP2976359B1 (en) 2018-08-29
HK1213576A1 (en) 2016-07-08
PT3312195T (pt) 2019-12-23
PL2976359T5 (pl) 2022-07-18
ES2700238T5 (es) 2022-05-20
MY172324A (en) 2019-11-21
EA032327B1 (ru) 2019-05-31
JP7016113B2 (ja) 2022-02-04
CN111000997A (zh) 2020-04-14
MX2015013402A (es) 2016-01-08
SI2976359T2 (sl) 2022-05-31
SG11201506683XA (en) 2015-09-29
DK3312195T3 (da) 2020-01-06
AU2014235933A1 (en) 2015-10-01
DK2976359T4 (da) 2022-06-13
EP3312195B1 (en) 2019-10-09
EP2976359A1 (en) 2016-01-27
US20160031979A1 (en) 2016-02-04
TWI629995B (zh) 2018-07-21
UY35493A (es) 2014-11-28
IL241461A0 (en) 2015-11-30
PL2976359T3 (pl) 2019-03-29
MX369360B (es) 2019-11-06
EP3640260A1 (en) 2020-04-22
US10377819B2 (en) 2019-08-13
US11230595B2 (en) 2022-01-25
US9598486B2 (en) 2017-03-21
JP6483086B2 (ja) 2019-03-13
IL241461B (en) 2021-12-01
MX389759B (es) 2025-03-20
JP2020109110A (ja) 2020-07-16
KR20150132262A (ko) 2015-11-25
PH12019500261B1 (en) 2021-03-26
RS58188B1 (sr) 2019-03-29
PH12015501864B1 (en) 2015-12-07
RS58188B2 (sr) 2022-06-30
CL2015002801A1 (es) 2016-08-12
US12365725B2 (en) 2025-07-22
JP2019089826A (ja) 2019-06-13
ES2700238T3 (es) 2019-02-14
CA2907422A1 (en) 2014-09-25
PL3312195T3 (pl) 2020-04-30
AU2014235933B2 (en) 2019-01-24
SI3312195T1 (sl) 2020-02-28
US20170247439A1 (en) 2017-08-31
EA201591843A1 (ru) 2016-01-29
BR112015023905A2 (pt) 2017-10-24
CA2907422C (en) 2021-08-31
HK1253717A1 (en) 2019-06-28
MX2019009122A (es) 2019-09-16
HUE046702T2 (hu) 2020-03-30
PT2976359T (pt) 2018-12-05
NZ712353A (en) 2021-04-30
LT2976359T (lt) 2018-12-27
CN105229028B (zh) 2019-11-08
US20190389943A1 (en) 2019-12-26
HRP20181939T4 (hr) 2022-05-13
PH12015501864A1 (en) 2015-12-07
JP6677837B2 (ja) 2020-04-08
PH12019500261A1 (en) 2020-07-20
RS59673B1 (sr) 2020-01-31

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