MX2015012202A - Metodos y materiales para diferenciacion hematoendotelial de celulas germinales pluripotentes humanas bajo condiciones definidas. - Google Patents
Metodos y materiales para diferenciacion hematoendotelial de celulas germinales pluripotentes humanas bajo condiciones definidas.Info
- Publication number
- MX2015012202A MX2015012202A MX2015012202A MX2015012202A MX2015012202A MX 2015012202 A MX2015012202 A MX 2015012202A MX 2015012202 A MX2015012202 A MX 2015012202A MX 2015012202 A MX2015012202 A MX 2015012202A MX 2015012202 A MX2015012202 A MX 2015012202A
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- differentiation
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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- C12N5/0056—Xeno-free medium
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/0636—T lymphocytes
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- C12N5/069—Vascular Endothelial cells
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
- C12N5/0695—Stem cells; Progenitor cells; Precursor cells
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- C12N2500/00—Specific components of cell culture medium
- C12N2500/02—Atmosphere, e.g. low oxygen conditions
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/16—Activin; Inhibin; Mullerian inhibiting substance
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/165—Vascular endothelial growth factor [VEGF]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1394—Bone marrow stromal cells; whole marrow
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Developmental Biology & Embryology (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Se describen métodos y composiciones para diferenciar células germinales pluripotentes en células de linajes endoteliales y hematopoyéticas.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361779564P | 2013-03-13 | 2013-03-13 | |
| PCT/US2014/024518 WO2014165131A1 (en) | 2013-03-13 | 2014-03-12 | Methods and materials for hematoendothelial differentiation of human pluripotent stem cells under defined conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2015012202A true MX2015012202A (es) | 2015-11-30 |
| MX366900B MX366900B (es) | 2019-07-30 |
Family
ID=50678273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2015012202A MX366900B (es) | 2013-03-13 | 2014-03-12 | Métodos y materiales para diferenciación hematoendotelial de células germinales pluripotentes humanas bajo condiciones definidas. |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US9938499B2 (es) |
| EP (1) | EP2970912B1 (es) |
| JP (1) | JP6677631B2 (es) |
| KR (1) | KR102151210B1 (es) |
| CN (1) | CN105209609B (es) |
| AU (1) | AU2014248651B2 (es) |
| BR (1) | BR112015022770B1 (es) |
| CA (2) | CA2905786C (es) |
| DK (1) | DK2970912T3 (es) |
| ES (1) | ES2720196T3 (es) |
| HU (1) | HUE043785T2 (es) |
| IL (1) | IL241286B (es) |
| MX (1) | MX366900B (es) |
| PL (1) | PL2970912T3 (es) |
| PT (1) | PT2970912T (es) |
| SG (1) | SG11201507275TA (es) |
| TR (1) | TR201904270T4 (es) |
| WO (1) | WO2014165131A1 (es) |
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| US9719068B2 (en) | 2010-05-06 | 2017-08-01 | Children's Hospital Medical Center | Methods and systems for converting precursor cells into intestinal tissues through directed differentiation |
| JP6677631B2 (ja) | 2013-03-13 | 2020-04-08 | ウイスコンシン アラムナイ リサーチ ファウンデーシヨンWisconsin Alumni Research Foundation | 定義された条件下におけるヒト多能性幹細胞の造血内皮分化のための方法及び材料 |
| US9868939B2 (en) | 2013-06-12 | 2018-01-16 | Wisconsin Alumni Research Foundation | Generating vasculogenic cell populations |
| CN106661548B (zh) | 2014-05-28 | 2020-12-11 | 儿童医院医疗中心 | 用于经由定向分化将前体细胞转化为胃组织的方法和系统 |
| JP6804438B2 (ja) | 2014-10-17 | 2020-12-23 | チルドレンズ ホスピタル メディカル センター | 多能性幹細胞を使用するヒト小腸のin vivoモデル、並びにそれを作製、及び使用する方法 |
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| EP4508645A1 (en) | 2022-04-15 | 2025-02-19 | Aspen Neuroscience, Inc. | Methods of classifying the differentiation state of cells and related compositions of differentiated cells |
| KR20250160941A (ko) * | 2023-02-16 | 2025-11-14 | 신택스 바이오, 인크. | 조혈 계통으로의 세포 프로그래밍을 위한 시스템 및 이의 방법 |
| TW202600811A (zh) * | 2024-03-01 | 2026-01-01 | 史丹佛大學董事會 | 生成內皮細胞的方法 |
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| US8034613B2 (en) | 2005-06-01 | 2011-10-11 | Wisconsin Alumni Research Foundation | Multipotent lymphohematopoietic progenitor cells |
| EP1885845A2 (en) | 2005-06-01 | 2008-02-13 | Wisconsin Alumni Research Foundation | Method of forming dendritic cells from embryonic stem cells |
| US20080070303A1 (en) | 2005-11-21 | 2008-03-20 | West Michael D | Methods to accelerate the isolation of novel cell strains from pluripotent stem cells and cells obtained thereby |
| CA2641967C (en) | 2006-02-09 | 2019-03-19 | Wisconsin Alumni Research Foundation | Erythroid cells producing adult-type .beta.-hemoglobin generated from human embryonic stem cells |
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| US7615374B2 (en) | 2007-09-25 | 2009-11-10 | Wisconsin Alumni Research Foundation | Generation of clonal mesenchymal progenitors and mesenchymal stem cell lines under serum-free conditions |
| US20110236971A2 (en) * | 2007-09-25 | 2011-09-29 | Maksym Vodyanyk | Generation of Clonal Mesenchymal Progenitors and Mesenchymal Stem Cell Lines Under Serum-Free Conditions |
| US8372643B2 (en) | 2007-12-06 | 2013-02-12 | Agency For Science, Technology And Research | Method for extracellular matrix mediated differentiation and proliferation of stem cells |
| JP5748654B2 (ja) | 2008-05-06 | 2015-07-15 | オカタ セラピューティクス, インコーポレイテッド | 多能性幹細胞に由来する除核赤血球細胞を産生するための方法 |
| KR101720961B1 (ko) * | 2009-02-27 | 2017-03-29 | 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 | 다능성 세포의 분화 |
| WO2010143529A1 (ja) * | 2009-06-09 | 2010-12-16 | 国立大学法人名古屋大学 | 多能性幹細胞を胸腺上皮へ分化誘導する方法 |
| EP2563908B1 (en) * | 2010-04-25 | 2019-01-09 | Icahn School of Medicine at Mount Sinai | Generation of anterior foregut endoderm from pluripotent cells |
| US9279107B2 (en) | 2010-08-05 | 2016-03-08 | Wisconsin Alumni Research Foundation | Simplified basic media for human pluripotent cell culture |
| JP6677631B2 (ja) | 2013-03-13 | 2020-04-08 | ウイスコンシン アラムナイ リサーチ ファウンデーシヨンWisconsin Alumni Research Foundation | 定義された条件下におけるヒト多能性幹細胞の造血内皮分化のための方法及び材料 |
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