MX2017016517A - Composiciones estables al almacenamiento y metodos para el tratamiento de errores de refraccion del ojo. - Google Patents

Composiciones estables al almacenamiento y metodos para el tratamiento de errores de refraccion del ojo.

Info

Publication number
MX2017016517A
MX2017016517A MX2017016517A MX2017016517A MX2017016517A MX 2017016517 A MX2017016517 A MX 2017016517A MX 2017016517 A MX2017016517 A MX 2017016517A MX 2017016517 A MX2017016517 A MX 2017016517A MX 2017016517 A MX2017016517 A MX 2017016517A
Authority
MX
Mexico
Prior art keywords
methods
treatment
storage
stable compositions
eye refraction
Prior art date
Application number
MX2017016517A
Other languages
English (en)
Other versions
MX373719B (es
Inventor
Horn Gerald
NORDAN Lee
Original Assignee
Presbyopia Therapies Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US14/742,921 external-priority patent/US9314427B2/en
Priority claimed from US14/742,903 external-priority patent/US9320709B2/en
Application filed by Presbyopia Therapies Llc filed Critical Presbyopia Therapies Llc
Publication of MX2017016517A publication Critical patent/MX2017016517A/es
Publication of MX373719B publication Critical patent/MX373719B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La invención provee composiciones y métodos para lograr aceclidina estable al almacenamiento; las composiciones comprenden preferiblemente aceclidina, un agente ciclopléjico, un tensoactivo, un ajustador de la tonicidad y opcionalmente un potenciador de la viscosidad y un antioxidante; la invención proporciona además métodos para tratar errores de refracción del ojo con una composición de acetilidina estable al almacenamiento.
MX2017016517A 2015-06-18 2016-06-09 Composiciones estables al almacenamiento y metodos para el tratamiento de errores de refraccion del ojo. MX373719B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14/742,921 US9314427B2 (en) 2013-08-28 2015-06-18 Compositions and methods for the improvement of distance vision and the treatment of refractive errors of the eye
US14/742,903 US9320709B2 (en) 2013-08-28 2015-06-18 Storage stable compositions and methods for the treatment of refractive errors of the eye
PCT/US2016/036687 WO2016205068A1 (en) 2015-06-18 2016-06-09 Storage stable compositions and methods for the treatment of refractive errors of the eye

Publications (2)

Publication Number Publication Date
MX2017016517A true MX2017016517A (es) 2018-05-28
MX373719B MX373719B (es) 2020-05-08

Family

ID=57545598

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2017016517A MX373719B (es) 2015-06-18 2016-06-09 Composiciones estables al almacenamiento y metodos para el tratamiento de errores de refraccion del ojo.
MX2017016518A MX373692B (es) 2015-06-18 2016-06-09 Composiciones y metodos para la mejora de la vision a distancia y el tratamiento de errores de refraccion del ojo.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2017016518A MX373692B (es) 2015-06-18 2016-06-09 Composiciones y metodos para la mejora de la vision a distancia y el tratamiento de errores de refraccion del ojo.

Country Status (9)

Country Link
EP (3) EP3310336A4 (es)
JP (3) JP6835747B2 (es)
KR (4) KR102667598B1 (es)
CN (3) CN107847492B (es)
AU (2) AU2016280616B2 (es)
CA (2) CA2987783A1 (es)
HK (1) HK1254338A1 (es)
MX (2) MX373719B (es)
WO (2) WO2016205068A1 (es)

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WO2018174149A1 (en) * 2017-03-23 2018-09-27 Singapore Health Services Pte Ltd Agent for preventing myopia, treating myopia, and/or preventing myopia progression comprising tiotropium as active ingredient
RU2745603C1 (ru) * 2017-05-11 2021-03-29 Невакар Инк. Фармацевтические композиции атропина
KR20210076941A (ko) * 2018-10-10 2021-06-24 프레스바이오피아 세라피스, 인코포레이티드 노안 치료를 위한 조성물 및 방법
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KR102762718B1 (ko) * 2022-02-23 2025-02-06 주식회사 스카이테라퓨틱스 고분자 히알루론산의 구조체, 이의 제조방법 및 이를 포함하는 화장료 조성물
KR102726207B1 (ko) * 2022-02-23 2024-11-05 주식회사 스카이테라퓨틱스 고분자 히알루론산의 구조체, 이의 제조방법 및 이를 포함하는 점안 조성물
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Also Published As

Publication number Publication date
CN107847492A (zh) 2018-03-27
CN116808032A (zh) 2023-09-29
CA2987783A1 (en) 2016-12-22
AU2016280615A1 (en) 2017-12-14
JP2021035954A (ja) 2021-03-04
BR112017025722A2 (pt) 2018-08-07
EP3310336A4 (en) 2018-12-05
WO2016205068A1 (en) 2016-12-22
JP2018517738A (ja) 2018-07-05
KR102598047B1 (ko) 2023-11-06
WO2016205069A1 (en) 2016-12-22
AU2016280616A1 (en) 2017-12-14
EP3310336A1 (en) 2018-04-25
BR112017025726A2 (pt) 2018-08-14
HK1254338A1 (zh) 2019-07-19
AU2016280615B2 (en) 2020-10-01
KR20180014824A (ko) 2018-02-09
CA2987787C (en) 2023-06-27
EP3310356A1 (en) 2018-04-25
EP4385521A3 (en) 2024-11-13
MX373692B (es) 2020-05-08
MX373719B (es) 2020-05-08
CN107847492B (zh) 2021-05-25
JP6838712B2 (ja) 2021-03-03
MX2017016518A (es) 2018-05-28
CA2987787A1 (en) 2016-12-22
CN107920984A (zh) 2018-04-17
KR102667598B1 (ko) 2024-05-20
JP6835747B2 (ja) 2021-02-24
KR20180014825A (ko) 2018-02-09
JP2018517740A (ja) 2018-07-05
KR20230085217A (ko) 2023-06-13
EP3310356A4 (en) 2018-12-05
EP4385521A2 (en) 2024-06-19
KR20230156161A (ko) 2023-11-13
AU2016280616B2 (en) 2020-10-22
JP7026189B2 (ja) 2022-02-25

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