MX9801603A - Alteraciones geneticas relacionadas con la enfermedad de alzheimer hereditaria. - Google Patents
Alteraciones geneticas relacionadas con la enfermedad de alzheimer hereditaria.Info
- Publication number
- MX9801603A MX9801603A MX9801603A MX9801603A MX9801603A MX 9801603 A MX9801603 A MX 9801603A MX 9801603 A MX9801603 A MX 9801603A MX 9801603 A MX9801603 A MX 9801603A MX 9801603 A MX9801603 A MX 9801603A
- Authority
- MX
- Mexico
- Prior art keywords
- disease
- methods
- genetic alterations
- familial alzheimer
- same
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Se proporcionan moléculas aisladas de ácidos nucleicos que codifican productos de genes PS1 humanos. Los polipéptidos mutantes de PS1 también se proporcionan así como los vectores, células huéspedes y métodos recombinantes para producir los mismos. La invencion además se relaciona con métodos de examen para identificar agonistas y antagonistas de la actividad del polipéptido PS1 y mutantes del mismo. También se proporcionan métodos de diagnosticos para detectar la enfermedad de Alzheimer y métodos terapéuticos para el tratamiento de la misma.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US305495P | 1995-08-31 | 1995-08-31 | |
| US003054 | 1995-08-31 | ||
| US08/706,344 US6248555B1 (en) | 1995-08-31 | 1996-08-30 | Genetic alterations related to familial alzheimer's disease |
| US08706344 | 1996-08-30 | ||
| PCT/US1996/014114 WO1997008319A1 (en) | 1995-08-31 | 1996-09-03 | Genetic alterations related to familial alzheimer's disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX9801603A true MX9801603A (es) | 1998-08-30 |
| MXPA98001603A MXPA98001603A (es) | 1998-11-12 |
Family
ID=
Also Published As
| Publication number | Publication date |
|---|---|
| US6248555B1 (en) | 2001-06-19 |
| WO1997008319A1 (en) | 1997-03-06 |
| US20010012626A1 (en) | 2001-08-09 |
| EP0851921A1 (en) | 1998-07-08 |
| JPH11512929A (ja) | 1999-11-09 |
| CA2230654A1 (en) | 1997-03-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO1998039446A3 (en) | 70 human secreted proteins | |
| WO1998039448A3 (en) | 186 human secreted proteins | |
| WO1998040483A3 (en) | 28 human secreted proteins | |
| WO1998030694A3 (en) | TUMOR NECROSIS FACTOR RECEPTORS 6α AND 6$g(b) | |
| EP1015468A4 (en) | FOLLISTATIN-3 | |
| WO1998031800A3 (en) | Human proteins | |
| CY1111950T1 (el) | 32 ανθρωπινες εκκρινομενες πρωτεϊνες | |
| WO2001036432A3 (en) | 18 human secreted proteins | |
| NZ279963A (en) | Human tissue inhibitor of metalloproteinase-4 (timp-4) and dna (rna) encoding polypeptide which may be derived from atcc 75946 | |
| WO1998045712A3 (en) | 20 human secreted proteins | |
| WO2001012776A3 (en) | 18 human secreted proteins | |
| WO2001034768A3 (en) | 15 human secreted proteins | |
| WO2000017222A8 (en) | 31 human secreted proteins | |
| WO2000077026A8 (en) | 49 human secreted proteins | |
| WO2000063230A3 (en) | 49 human secreted proteins | |
| WO2001012775A3 (en) | 25 human secreted proteins | |
| WO2000058339A3 (en) | 50 human secreted proteins | |
| MX9801603A (es) | Alteraciones geneticas relacionadas con la enfermedad de alzheimer hereditaria. | |
| WO2000043495A3 (en) | 33 human secreted proteins | |
| WO2000061624A8 (en) | 48 human secreted proteins | |
| ATE300554T1 (de) | Bindegewebe-wachstumsfaktor 3. | |
| WO2003052377A9 (en) | 41 human secreted proteins | |
| WO2000061596A8 (en) | 50 human secreted proteins | |
| WO2001034769A3 (en) | 24 human secreted proteins | |
| WO2001023409A8 (en) | 38 human secreted proteins |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |