NO20000913L - Sfæriske mikropartikler inneholdende lineære polysakkarider - Google Patents
Sfæriske mikropartikler inneholdende lineære polysakkariderInfo
- Publication number
- NO20000913L NO20000913L NO20000913A NO20000913A NO20000913L NO 20000913 L NO20000913 L NO 20000913L NO 20000913 A NO20000913 A NO 20000913A NO 20000913 A NO20000913 A NO 20000913A NO 20000913 L NO20000913 L NO 20000913L
- Authority
- NO
- Norway
- Prior art keywords
- containing linear
- microparticles containing
- spherical microparticles
- linear polysaccharides
- polyglucan
- Prior art date
Links
- 150000004676 glycans Chemical class 0.000 title abstract 3
- 239000011859 microparticle Substances 0.000 title abstract 3
- 229920001282 polysaccharide Polymers 0.000 title abstract 3
- 239000005017 polysaccharide Substances 0.000 title abstract 3
- 239000013543 active substance Substances 0.000 abstract 2
- 229920002988 biodegradable polymer Polymers 0.000 abstract 1
- 239000004621 biodegradable polymer Substances 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/12—Powdering or granulating
- C08J3/14—Powdering or granulating by precipitation from solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- General Preparation And Processing Of Foods (AREA)
Abstract
Det beskrives mikropartikJer med ensformig sfærisk utforming, som utviser en meget smal størrelsesfordeling. De består helt eller delvis av et lineært vannuoppløselig polysakkarid, fortrinnsvis av 1,4-a-D-polyglukan og kan videre spesielt inneholde biologisk nedbrytbare polymerer og/eller virkestoffer. Mikropartiklene er blant annet egnet for den kontrollerte frigivning av virkestoffer. De blir fremstilt gjennom oppløsning av 1,4-a-D-polyglukan eller polysakkaridet i løsemiddel, innføring av oppløsningen i et felningsmiddel, kjøling av blandingen og utskillelse av de dannede partiklene.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19737481A DE19737481A1 (de) | 1997-08-28 | 1997-08-28 | Sphärische lineare Polysaccharide enthaltende Mikropartikel |
| PCT/EP1998/005297 WO1999011695A1 (de) | 1997-08-28 | 1998-08-20 | Sphärische lineare polysaccharide enthaltende mikropartikel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20000913D0 NO20000913D0 (no) | 2000-02-24 |
| NO20000913L true NO20000913L (no) | 2000-02-24 |
Family
ID=7840425
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20000913A NO20000913L (no) | 1997-08-28 | 2000-02-24 | Sfæriske mikropartikler inneholdende lineære polysakkarider |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US6703048B1 (no) |
| EP (1) | EP1012204B1 (no) |
| JP (1) | JP2001514315A (no) |
| KR (1) | KR20010023330A (no) |
| CN (1) | CN1177884C (no) |
| AU (1) | AU9532798A (no) |
| CA (1) | CA2302346A1 (no) |
| DE (2) | DE19737481A1 (no) |
| ES (1) | ES2191970T3 (no) |
| HU (1) | HUP0003482A3 (no) |
| NO (1) | NO20000913L (no) |
| PL (1) | PL338802A1 (no) |
| WO (1) | WO1999011695A1 (no) |
| ZA (1) | ZA987786B (no) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19737481A1 (de) * | 1997-08-28 | 1999-03-04 | Hoechst Ag | Sphärische lineare Polysaccharide enthaltende Mikropartikel |
| DE19816070A1 (de) * | 1998-04-09 | 1999-10-14 | Aventis Res & Tech Gmbh & Co | Retardtablette hergestellt aus linearen wasserunlöslichen Polysacchariden |
| WO1999052506A1 (de) * | 1998-04-09 | 1999-10-21 | Axiva Gmbh | Partikulärer wirkstoffträger für die pulmonale applikation |
| DE19839212C2 (de) * | 1998-08-28 | 2002-05-23 | Celanese Ventures Gmbh | Verfahren zur Herstellung von sphärischen Nanopartikeln, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen |
| DE19839214C1 (de) * | 1998-08-28 | 2000-05-25 | Aventis Res & Tech Gmbh & Co | Verfahren zur Herstellung von sphärischen Mikropartikeln mit glatter Oberfläche, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen, sowie mit diesem Verfahren erhältliche Mikropartikel und deren Verwendung |
| DE19839216C1 (de) * | 1998-08-28 | 2000-01-20 | Aventis Res & Tech Gmbh & Co | Verfahren zur Herstellung von sphärischen Mikropartikeln, die ganz oder teilweise aus mindestens einem wasserunlöslichen Verzweigungen enthaltenden Polyglucan bestehen, sowie mit diesem Verfahren erhältliche Mikropartikel und die Verwendung |
| DE19847593A1 (de) * | 1998-10-15 | 2000-04-20 | Aventis Res & Tech Gmbh & Co | Zusammensetzung für die parenterale Applikation von Wirkstoffen |
| DE19852826A1 (de) * | 1998-11-17 | 2000-05-18 | Aventis Res & Tech Gmbh & Co | Poly(alpha-1,4-D-Glucan) |
| DE19860374A1 (de) * | 1998-12-28 | 2000-07-06 | Aventis Res & Tech Gmbh & Co | Verwendung von resistenter Stärke als Mehlersatzstoff für Nahrungsmittel und Nahrungsmittelinhaltsstoffe |
| DE19860371A1 (de) | 1998-12-28 | 2000-06-29 | Aventis Res & Tech Gmbh & Co | Kosmetische oder medizinische Zubereitung für die topische Anwendung |
| DE19860367A1 (de) * | 1998-12-28 | 2000-08-03 | Aventis Res & Tech Gmbh & Co | Mundpflegemittel enthaltend ein lineares wasserunlösliches Poly-alpha-glucan |
| ATE307554T1 (de) * | 1998-12-28 | 2005-11-15 | Suedzucker Ag | Sonnenschutzmittel mit mikropartikeln auf basis von wasserunlöslichem linearem polyglucan |
| DE19860366A1 (de) * | 1998-12-28 | 2000-06-29 | Aventis Res & Tech Gmbh & Co | Kosmetische oder medizinische Zubereitung für die topische Anwendung |
| DE19860373B4 (de) * | 1998-12-28 | 2004-02-19 | Celanese Ventures Gmbh | Mundpflegemittel und Verwendung von sphärischen Mikropartikeln |
| DE19902917C2 (de) * | 1999-01-26 | 2001-03-29 | Aventis Res & Tech Gmbh & Co | Wasserunlösliche lineare Polysaccharide zur Filtration |
| DE19911058B4 (de) * | 1999-03-12 | 2004-09-30 | Biotec Asa | Verwendung von nanoskaligen wasserlöslichen β-(1,3)-Glucanen |
| DE10053267B4 (de) * | 2000-10-26 | 2005-12-22 | Celanese Ventures Gmbh | Verfahren zur Herstellung von mikrosphärischen Kristalliten, danach hergestellte mikrosphärische Kristallite und deren Verwendung |
| US20050048126A1 (en) | 2000-12-22 | 2005-03-03 | Barrett Rabinow | Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug |
| US7193084B2 (en) | 2000-12-22 | 2007-03-20 | Baxter International Inc. | Polymorphic form of itraconazole |
| US6951656B2 (en) | 2000-12-22 | 2005-10-04 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
| US6884436B2 (en) | 2000-12-22 | 2005-04-26 | Baxter International Inc. | Method for preparing submicron particle suspensions |
| US6977085B2 (en) | 2000-12-22 | 2005-12-20 | Baxter International Inc. | Method for preparing submicron suspensions with polymorph control |
| US6869617B2 (en) | 2000-12-22 | 2005-03-22 | Baxter International Inc. | Microprecipitation method for preparing submicron suspensions |
| US9700866B2 (en) | 2000-12-22 | 2017-07-11 | Baxter International Inc. | Surfactant systems for delivery of organic compounds |
| US8067032B2 (en) | 2000-12-22 | 2011-11-29 | Baxter International Inc. | Method for preparing submicron particles of antineoplastic agents |
| KR100457546B1 (ko) * | 2001-05-02 | 2004-11-18 | 주식회사 바이오프로젠 | 폴리프럭토오스 또는 그 유도체를 이용한 미소구 및 그제조방법 |
| US20060003012A9 (en) | 2001-09-26 | 2006-01-05 | Sean Brynjelsen | Preparation of submicron solid particle suspensions by sonication of multiphase systems |
| JP2005504090A (ja) | 2001-09-26 | 2005-02-10 | バクスター・インターナショナル・インコーポレイテッド | 分散体および溶媒相または液相の除去によるサブミクロンサイズ−ナノ粒子の調製 |
| US7112340B2 (en) | 2001-10-19 | 2006-09-26 | Baxter International Inc. | Compositions of and method for preparing stable particles in a frozen aqueous matrix |
| JP4959191B2 (ja) | 2003-07-11 | 2012-06-20 | 旭化成ケミカルズ株式会社 | 機能性澱粉粉末 |
| DE102005022639B4 (de) * | 2005-05-11 | 2009-01-15 | Technische Universität Clausthal | Verfahren zur Extraktion von Nano- bis Mikropartikeln |
| ATE454908T1 (de) * | 2005-09-21 | 2010-01-15 | Surmodics Inc | In situ okklusionszusammensetzungen mit natürlichen biologisch abbaubaren polysacchariden |
| CA2621595A1 (en) * | 2005-09-21 | 2007-04-12 | Surmodics, Inc. | Coatings and articles including natural biodegradable polysaccharides |
| US20080286410A1 (en) * | 2007-03-06 | 2008-11-20 | Richmond Patricia A | Production of Resistant Starch Product |
| US8426467B2 (en) | 2007-05-22 | 2013-04-23 | Baxter International Inc. | Colored esmolol concentrate |
| US8722736B2 (en) | 2007-05-22 | 2014-05-13 | Baxter International Inc. | Multi-dose concentrate esmolol with benzyl alcohol |
| WO2009005718A1 (en) * | 2007-06-28 | 2009-01-08 | Surmodics, Inc. | Polypeptide microparticles having sustained release characteristics, methods and uses |
| JP5763525B2 (ja) * | 2008-05-07 | 2015-08-12 | サーモディクス,インコーポレイティド | 粒子からの核酸複合体の送達 |
| EP2246366A1 (en) | 2009-03-24 | 2010-11-03 | Mondi Limited South Africa | Process and device for preparing starch microgel particles for the paper industry |
| EP2246472A1 (en) | 2009-03-24 | 2010-11-03 | Mondi Limited South Africa | Process for preparing polysaccharide gel particles and pulp furnish for use in paper making |
| US8901092B2 (en) | 2010-12-29 | 2014-12-02 | Surmodics, Inc. | Functionalized polysaccharides for active agent delivery |
| FR3026105B1 (fr) * | 2014-09-24 | 2019-04-19 | Greenpharma | Composition contenant au moins un inhibiteur de certaines chimiokines, son procede d'obtention et son utilisation dermocosmetique ou pharmaceutique |
| JP7701050B2 (ja) * | 2019-11-14 | 2025-07-01 | 国立大学法人九州大学 | 中間水を含有可能な非水溶性ポリマーの水和方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS551244B1 (no) * | 1970-12-29 | 1980-01-12 | ||
| US3915800A (en) * | 1972-03-30 | 1975-10-28 | Kelco Co | Polysaccharide and bacterial fermentation process for its preparation |
| JPS511372A (en) * | 1974-06-22 | 1976-01-08 | Sumitomo Chemical Co | Zoryu hifukuhoho |
| JPS5326867A (en) * | 1976-08-24 | 1978-03-13 | Hayashibara Biochem Lab | Method of endowment of waterrproof ability of formed product belonging to poluran series |
| US4438200A (en) * | 1982-09-13 | 1984-03-20 | Forsyth Dental Infirmary For Children | Method for the preparation of glucosylranferase |
| US4992540A (en) * | 1984-11-28 | 1991-02-12 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
| US4968350A (en) * | 1987-04-16 | 1990-11-06 | Christian Bindschaedler | Process for preparing a powder of water-insoluble polymer which can be redispersed in a liquid phase, the resulting powder and utilization thereof |
| US5032401A (en) * | 1989-06-15 | 1991-07-16 | Alpha Beta Technology | Glucan drug delivery system and adjuvant |
| JP2926434B2 (ja) * | 1990-07-26 | 1999-07-28 | 株式会社林原生物化学研究所 | アミロース粒子とその製造方法 |
| DE4120760A1 (de) * | 1991-06-24 | 1993-03-04 | 3 M Medica Gmbh | Traegersysteme fuer arzneimittel |
| NL9201196A (nl) * | 1992-07-03 | 1994-02-01 | Tno | Preparaat voor de gereguleerde afgifte van een werkzame stof en werkwijze ter bereiding van een dergelijk preparaat. |
| US5472859A (en) * | 1993-08-02 | 1995-12-05 | Brown, Jr.; R. Malcolm | Enzymatic method for synthesis of cellulose 1 |
| US5961970A (en) * | 1993-10-29 | 1999-10-05 | Pharmos Corporation | Submicron emulsions as vaccine adjuvants |
| PT759993E (pt) * | 1994-05-18 | 2007-08-10 | Bayer Bioscience Gmbh | ''sequências de dna que codificam para enzimas capazes de facilitar a síntese de alfa-1,4-glucanos lineares em plantas, fungos e microrganismos'' |
| US5576015A (en) * | 1995-03-02 | 1996-11-19 | Donzis; Byron A. | Substantially purified beta (1,3) finely ground yeast cell wall glucan composition with dermatological and nutritional uses |
| DE19737481A1 (de) * | 1997-08-28 | 1999-03-04 | Hoechst Ag | Sphärische lineare Polysaccharide enthaltende Mikropartikel |
| DE19839216C1 (de) * | 1998-08-28 | 2000-01-20 | Aventis Res & Tech Gmbh & Co | Verfahren zur Herstellung von sphärischen Mikropartikeln, die ganz oder teilweise aus mindestens einem wasserunlöslichen Verzweigungen enthaltenden Polyglucan bestehen, sowie mit diesem Verfahren erhältliche Mikropartikel und die Verwendung |
| DE19839214C1 (de) * | 1998-08-28 | 2000-05-25 | Aventis Res & Tech Gmbh & Co | Verfahren zur Herstellung von sphärischen Mikropartikeln mit glatter Oberfläche, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen, sowie mit diesem Verfahren erhältliche Mikropartikel und deren Verwendung |
| DE19839212C2 (de) * | 1998-08-28 | 2002-05-23 | Celanese Ventures Gmbh | Verfahren zur Herstellung von sphärischen Nanopartikeln, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen |
-
1997
- 1997-08-28 DE DE19737481A patent/DE19737481A1/de not_active Withdrawn
-
1998
- 1998-08-20 EP EP98948849A patent/EP1012204B1/de not_active Expired - Lifetime
- 1998-08-20 JP JP2000508724A patent/JP2001514315A/ja active Pending
- 1998-08-20 WO PCT/EP1998/005297 patent/WO1999011695A1/de not_active Ceased
- 1998-08-20 CN CNB988086077A patent/CN1177884C/zh not_active Expired - Fee Related
- 1998-08-20 CA CA002302346A patent/CA2302346A1/en not_active Abandoned
- 1998-08-20 DE DE59807084T patent/DE59807084D1/de not_active Expired - Lifetime
- 1998-08-20 AU AU95327/98A patent/AU9532798A/en not_active Abandoned
- 1998-08-20 KR KR1020007001967A patent/KR20010023330A/ko not_active Withdrawn
- 1998-08-20 HU HU0003482A patent/HUP0003482A3/hu unknown
- 1998-08-20 ES ES98948849T patent/ES2191970T3/es not_active Expired - Lifetime
- 1998-08-20 US US09/486,357 patent/US6703048B1/en not_active Expired - Fee Related
- 1998-08-20 PL PL98338802A patent/PL338802A1/xx unknown
- 1998-08-27 ZA ZA987786A patent/ZA987786B/xx unknown
-
2000
- 2000-02-24 NO NO20000913A patent/NO20000913L/no not_active Application Discontinuation
-
2004
- 2004-02-06 US US10/774,205 patent/US20040161830A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010023330A (ko) | 2001-03-26 |
| CN1177884C (zh) | 2004-12-01 |
| CA2302346A1 (en) | 1999-03-11 |
| ES2191970T3 (es) | 2003-09-16 |
| AU9532798A (en) | 1999-03-22 |
| WO1999011695A1 (de) | 1999-03-11 |
| NO20000913D0 (no) | 2000-02-24 |
| HUP0003482A2 (hu) | 2001-05-28 |
| US6703048B1 (en) | 2004-03-09 |
| JP2001514315A (ja) | 2001-09-11 |
| HUP0003482A3 (en) | 2001-06-28 |
| PL338802A1 (en) | 2000-11-20 |
| CN1268153A (zh) | 2000-09-27 |
| EP1012204B1 (de) | 2003-01-29 |
| DE19737481A1 (de) | 1999-03-04 |
| EP1012204A1 (de) | 2000-06-28 |
| US20040161830A1 (en) | 2004-08-19 |
| DE59807084D1 (de) | 2003-03-06 |
| ZA987786B (en) | 1999-03-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |