NO20055001L - Nytt difenylazetidinon med forbedrede fysiologiske egenskaper, fremgangsmate for fremstilling derav, legemiddel inneholdende forbindelsen og anvendelse derav - Google Patents

Nytt difenylazetidinon med forbedrede fysiologiske egenskaper, fremgangsmate for fremstilling derav, legemiddel inneholdende forbindelsen og anvendelse derav

Info

Publication number
NO20055001L
NO20055001L NO20055001A NO20055001A NO20055001L NO 20055001 L NO20055001 L NO 20055001L NO 20055001 A NO20055001 A NO 20055001A NO 20055001 A NO20055001 A NO 20055001A NO 20055001 L NO20055001 L NO 20055001L
Authority
NO
Norway
Prior art keywords
preparation
new
diphenylazetidinone
drug
containing compound
Prior art date
Application number
NO20055001A
Other languages
English (en)
Norwegian (no)
Inventor
Heiner Glombik
Hubert Heuer
Werner Kramer
Wendelin Frick
Hans-Ludwig Schaefer
Andreas Lindenschmidt
Gerhard Jaehne
Stefanie Flohr
Eric Galia
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of NO20055001L publication Critical patent/NO20055001L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/16Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • C07C233/17Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/18Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO20055001A 2003-04-01 2005-10-27 Nytt difenylazetidinon med forbedrede fysiologiske egenskaper, fremgangsmate for fremstilling derav, legemiddel inneholdende forbindelsen og anvendelse derav NO20055001L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10314610A DE10314610A1 (de) 2003-04-01 2003-04-01 Neues Diphenylazetidinon mit verbesserten physiologischen Eigenschaften, Verfahren zu dessen Herstellung, diese Verbindungen enthaltende Arzneimittel und dessen Verwendung
PCT/EP2004/002690 WO2004087655A1 (fr) 2003-04-01 2004-03-16 Nouveau diphenylazetidinone a proprietes physiologiques ameliorees, procedes de production associe, medicaments contenant les composes et leurs utilisations

Publications (1)

Publication Number Publication Date
NO20055001L true NO20055001L (no) 2005-10-27

Family

ID=33103147

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055001A NO20055001L (no) 2003-04-01 2005-10-27 Nytt difenylazetidinon med forbedrede fysiologiske egenskaper, fremgangsmate for fremstilling derav, legemiddel inneholdende forbindelsen og anvendelse derav

Country Status (43)

Country Link
US (2) US7205290B2 (fr)
EP (2) EP1613589B1 (fr)
JP (1) JP2006522040A (fr)
KR (1) KR20050119180A (fr)
CN (2) CN100361970C (fr)
AR (1) AR043783A1 (fr)
AT (2) ATE423766T1 (fr)
AU (1) AU2004226287B2 (fr)
BR (1) BRPI0408920A (fr)
CA (1) CA2520689A1 (fr)
CL (1) CL43489B (fr)
CR (1) CR7995A (fr)
CY (2) CY1107398T1 (fr)
DE (3) DE10314610A1 (fr)
DK (2) DK1862455T3 (fr)
EC (1) ECSP056071A (fr)
ES (2) ES2298731T3 (fr)
GT (1) GT200400058A (fr)
HN (1) HN2004000109A (fr)
HR (1) HRP20050870A2 (fr)
JO (1) JO2493B1 (fr)
MA (1) MA27753A1 (fr)
ME (1) MEP41408A (fr)
MX (1) MXPA05010128A (fr)
MY (1) MY136269A (fr)
NI (1) NI200500164A (fr)
NO (1) NO20055001L (fr)
NZ (1) NZ542751A (fr)
PA (1) PA8599401A1 (fr)
PE (1) PE20050011A1 (fr)
PL (2) PL1613589T3 (fr)
PT (2) PT1862455E (fr)
RS (1) RS51146B (fr)
RU (1) RU2334737C2 (fr)
SA (1) SA04250154B1 (fr)
SI (2) SI1862455T1 (fr)
SV (1) SV2004001756A (fr)
TN (1) TNSN05244A1 (fr)
TW (1) TW200504009A (fr)
UA (1) UA80754C2 (fr)
UY (1) UY28253A1 (fr)
WO (1) WO2004087655A1 (fr)
ZA (1) ZA200506708B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP20030498A2 (en) * 2000-12-21 2005-04-30 Aventis Pharma Deutschland Gmbh Novel 1,2-diphenzylazetidinones, method for producing the same, medicaments containing said compounds, and the use thereof for treating disorders of the lipid metabolism
DE602006010870D1 (de) 2005-06-20 2010-01-14 Schering Corp Als antagonisten von histamin h3 geeignete piperidinderivate
US7067689B1 (en) 2005-07-08 2006-06-27 Microbia, Inc. Process for production of pentahydroxyhexylcarbamoyl alkanoic acids
JP2010500300A (ja) 2006-08-08 2010-01-07 サノフィ−アベンティス アリールアミノアリール−アルキル−置換イミダゾリジン−2,4−ジオン、それらの製造法、それらの化合物を含有する薬剤、およびそれらの使用
US20080319221A1 (en) * 2007-06-22 2008-12-25 Bernd Junker Esters of Pentahydroxyhexylcarbamoyl Alkanoic Acids
DE102007029612A1 (de) * 2007-06-27 2009-01-08 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Pentahydroxyhexylcarbamoylundekan- säurebenzylester
US20080319218A1 (en) * 2007-06-22 2008-12-25 Andreas Haubrich Processes for Making and Using Benzyl Pentahydroxyhexylcarbamoylundecanoate
EP2025674A1 (fr) 2007-08-15 2009-02-18 sanofi-aventis Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament
DE102007054497B3 (de) * 2007-11-13 2009-07-23 Sanofi-Aventis Deutschland Gmbh Neue kristalline Diphenylazetidinonhydrate und Verfahren zu deren Herstellung
EA018974B9 (ru) * 2008-02-05 2014-04-30 Харбор Терапьютикс, Инк. Твердые лекарственные формы
DE102008059772A1 (de) 2008-12-01 2010-06-02 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung eines Diphenylazetidinons
WO2009112203A1 (fr) * 2008-03-14 2009-09-17 Sanofi-Aventis Deutschland Gmbh Procédé de fabrication d’une diphénylazétidinone
DE102010015123A1 (de) 2010-04-16 2011-10-20 Sanofi-Aventis Deutschland Gmbh Benzylamidische Diphenylazetidinone, diese Verbindungen enthaltende Arzneimittel und deren Verwendung
WO2011157827A1 (fr) 2010-06-18 2011-12-22 Sanofi Dérivés d'azolopyridin-3-one en tant qu'inhibiteurs de lipases et de phospholipases
EP2683702B1 (fr) 2011-03-08 2014-12-24 Sanofi Nouveaux dérivés de phényle-oxathiazine substitués, leur procédé de fabrication, médicament contenant ces liaisons et son utilisation
EP2683701B1 (fr) 2011-03-08 2014-12-24 Sanofi Dérivés d'oxathiazine substitués par des groupes de benzyle-méthyles ou d'hétéro-méthyles, leur procédé de fabrication, leur utilisation comme médicament ainsi que médicaments en étant pourvu et leur utilisation
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
US8895547B2 (en) 2011-03-08 2014-11-25 Sanofi Substituted phenyl-oxathiazine derivatives, method for producing them, drugs containing said compounds and the use thereof
EP2683705B1 (fr) 2011-03-08 2015-04-22 Sanofi Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
WO2012120052A1 (fr) 2011-03-08 2012-09-13 Sanofi Dérivés d'oxathiazine substitués par des carbocycles ou des hétérocycles, leur procédé de préparation, médicaments contenant ces composés et leur utilisation
EP2683699B1 (fr) 2011-03-08 2015-06-24 Sanofi Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation
EP2683698B1 (fr) 2011-03-08 2017-10-04 Sanofi Dérivés benzyl-oxathiazine substitués avec adamantane ou noradamantane, médicaments contenant ces composés et leur utilisation
US8871758B2 (en) 2011-03-08 2014-10-28 Sanofi Tetrasubstituted oxathiazine derivatives, method for producing them, their use as medicine and drug containing said derivatives and the use thereof
EP2567959B1 (fr) 2011-09-12 2014-04-16 Sanofi Dérivés d'amide d'acide 6-(4-hydroxy-phényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase
US10426480B2 (en) * 2015-04-29 2019-10-01 Covidien Lp Cutting ring assembly with rigid cutting member

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US576470A (en) * 1897-02-02 Boiler-furnace
FR2663336B1 (fr) 1990-06-18 1992-09-04 Adir Nouveaux derives peptidiques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5756740A (en) * 1992-04-08 1998-05-26 Eastman Kodak Company Process for the preparation of binary sensitizing dyes
FR2713225B1 (fr) 1993-12-02 1996-03-01 Sanofi Sa N-pipéridino-3-pyrazolecarboxamide substitué.
US5631365A (en) * 1993-09-21 1997-05-20 Schering Corporation Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
US5633246A (en) * 1994-11-18 1997-05-27 Schering Corporation Sulfur-substituted azetidinone compounds useful as hypocholesterolemic agents
AU727775B2 (en) 1996-01-17 2000-12-21 Novo Nordisk A/S Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use
IL128332A0 (en) 1996-08-30 2000-01-31 Novo Nordisk As GLP-1 derivatives
US5756470A (en) * 1996-10-29 1998-05-26 Schering Corporation Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
DE19726167B4 (de) 1997-06-20 2008-01-24 Sanofi-Aventis Deutschland Gmbh Insulin, Verfahren zu seiner Herstellung und es enthaltende pharmazeutische Zubereitung
PL338013A1 (en) 1997-07-16 2000-09-25 Novo Nordisk As Derivatives of condensed 1,2,4-thiadiazine, their production and application
CO4970713A1 (es) 1997-09-19 2000-11-07 Sanofi Synthelabo Derivados de carboxamidotiazoles, su preparacion, composiciones farmaceuticas que los contienen
WO1999046262A1 (fr) 1998-03-12 1999-09-16 Teijin Limited Derives de benzofurylpyrone
US6221897B1 (en) 1998-06-10 2001-04-24 Aventis Pharma Deutschland Gmbh Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
DE19845405C2 (de) * 1998-10-02 2000-07-13 Aventis Pharma Gmbh Arylsubstituierte Propanolaminderivate und deren Verwendung
DE69922043T2 (de) 1998-12-07 2005-11-24 Société de Conseils de Recherches et d'Applications Scientifiques S.A.S. Glp-1 analoge
GB9900416D0 (en) 1999-01-08 1999-02-24 Alizyme Therapeutics Ltd Inhibitors
EP1177176B1 (fr) 1999-04-28 2006-04-19 Aventis Pharma Deutschland GmbH Derives d'acide tri-aryle en tant que ligands pour recepteur de peroxisome a activation par proliferateur (ppar)
NZ515086A (en) 1999-04-28 2003-10-31 Aventis Pharma Gmbh Di-aryl acid derivatives as PPAR receptor ligands
GB9911863D0 (en) 1999-05-21 1999-07-21 Knoll Ag Therapeutic agents
DE60029446T2 (de) 1999-06-18 2007-02-08 Merck & Co., Inc. Arylthiazolidindione und aryloxazolidindion-derivate
EP1076066A1 (fr) 1999-07-12 2001-02-14 Zealand Pharmaceuticals A/S Peptides abaissant le taux de glucose sanguin
BR0012752A (pt) 1999-07-29 2002-04-02 Lilly Co Eli Benzofuril piperazinas e benzofuril homopiperazinas: agonistas de serotonina
HUP0202472A3 (en) 1999-09-01 2005-03-29 Aventis Pharma Gmbh Sulfonyl carboxiamide derivatives, method for their production and their use as medicaments
WO2001062266A2 (fr) 2000-02-25 2001-08-30 Novo Nordisk A/S Inhibition de la degenerescence des cellules beta
AU5257401A (en) 2000-04-28 2001-11-12 Asahi Chemical Ind Novel bicyclic compounds
DE60115227T2 (de) 2000-05-11 2006-08-24 Bristol-Myers Squibb Co. Tetrahydroisochinolin-analoga als wachstumshormon-sekretagoga
SE0001899D0 (sv) 2000-05-22 2000-05-22 Pharmacia & Upjohn Ab New compounds
HUP0004741A2 (hu) 2000-11-28 2002-12-28 Sanofi-Synthelabo Kémiai eljárás tiazolszármazékok előállítására és új intermedier
HRP20030498A2 (en) * 2000-12-21 2005-04-30 Aventis Pharma Deutschland Gmbh Novel 1,2-diphenzylazetidinones, method for producing the same, medicaments containing said compounds, and the use thereof for treating disorders of the lipid metabolism
DE10139416A1 (de) 2001-08-17 2003-03-06 Aventis Pharma Gmbh Aminoalkyl substituierte aromatische Bicyclen, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
HRP20040199A2 (en) 2001-08-31 2005-04-30 Aventis Pharma Deutschland Gmbh Diaryl cycloalkyl derivatives, method for producing the same and the use thereof as ppar activators
US6884812B2 (en) 2001-08-31 2005-04-26 Aventis Pharma Deutschland Gmbh Diarylcycloalkyl derivatives, processes for their preparation and their use as pharmaceuticals
US7176194B2 (en) * 2002-06-19 2007-02-13 Sanofi-Aventis Deutschland Gmbh Ring-substituted diphenylazetidinones, process for their preparation, medicaments comprising these compounds, and their use
GB0215579D0 (en) * 2002-07-05 2002-08-14 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
BRPI0408920A (pt) 2006-03-28
DE502004009059D1 (de) 2009-04-09
PA8599401A1 (es) 2004-10-08
KR20050119180A (ko) 2005-12-20
EP1613589B1 (fr) 2008-02-13
PT1862455E (pt) 2009-04-23
SV2004001756A (es) 2004-11-18
US20070197498A1 (en) 2007-08-23
CN100361970C (zh) 2008-01-16
EP1862455A2 (fr) 2007-12-05
CY1107398T1 (el) 2012-12-19
HN2004000109A (es) 2008-02-21
RS51146B (sr) 2010-10-31
US7205290B2 (en) 2007-04-17
CN101139306A (zh) 2008-03-12
GT200400058A (es) 2004-11-10
HRP20050870A2 (en) 2006-10-31
NI200500164A (es) 2006-01-11
SI1613589T1 (sl) 2008-06-30
DK1862455T3 (da) 2009-06-02
ATE386020T1 (de) 2008-03-15
UY28253A1 (es) 2004-11-08
PL1862455T3 (pl) 2009-07-31
EP1862455B1 (fr) 2009-02-25
CN1768034A (zh) 2006-05-03
RU2334737C2 (ru) 2008-09-27
CY1109055T1 (el) 2014-07-02
PE20050011A1 (es) 2005-02-28
CR7995A (es) 2006-09-22
US7772429B2 (en) 2010-08-10
ES2322876T3 (es) 2009-06-30
AR043783A1 (es) 2005-08-10
EP1862455A3 (fr) 2007-12-12
WO2004087655A1 (fr) 2004-10-14
ECSP056071A (es) 2006-01-27
CL43489B (es) 2005-01-21
SA04250154B1 (ar) 2007-10-29
RU2005133631A (ru) 2006-03-10
DK1613589T3 (da) 2008-06-09
HK1087697A1 (zh) 2006-10-20
UA80754C2 (en) 2007-10-25
NZ542751A (en) 2007-05-31
PT1613589E (pt) 2008-03-27
MEP41408A (en) 2011-02-10
ES2298731T3 (es) 2008-05-16
TNSN05244A1 (en) 2007-06-11
RS20050719A (sr) 2008-04-04
ZA200506708B (en) 2007-01-31
MXPA05010128A (es) 2005-11-16
DE502004006195D1 (de) 2008-03-27
ATE423766T1 (de) 2009-03-15
EP1613589A1 (fr) 2006-01-11
PL1613589T3 (pl) 2008-07-31
JO2493B1 (en) 2009-10-05
AU2004226287B2 (en) 2010-03-18
US20050020563A1 (en) 2005-01-27
CA2520689A1 (fr) 2004-10-14
MY136269A (en) 2008-09-30
MA27753A1 (fr) 2006-02-01
DE10314610A1 (de) 2004-11-04
JP2006522040A (ja) 2006-09-28
TW200504009A (en) 2005-02-01
SI1862455T1 (sl) 2009-06-30
AU2004226287A1 (en) 2004-10-14

Similar Documents

Publication Publication Date Title
NO20055001L (no) Nytt difenylazetidinon med forbedrede fysiologiske egenskaper, fremgangsmate for fremstilling derav, legemiddel inneholdende forbindelsen og anvendelse derav
NO20080789L (no) 1,4-benzotiazepin 1,1-dioksidderivater, fremgangsmate for fremstilling derav, medikamenter inneholdende denne forbindelsen og anvendelse derav som et hypolipid
BG108318A (en) Carboxamide-substituted phenylurea derivatives and method for the production and use thereof as medicaments
NO20091893L (no) Nye 1,4-benzotiepin-1,1-dioksidderivater som er substituert med benzylgrupper, fremgangsmater for fremstilling av medisiner inneholdende forbindelsene og anvendelse derav.
IL173203A0 (en) Novel cyano thiazolides, methods for the production thereof, and use thereof as a medicament
MY142830A (en) Propionic acid derivatives useful in the treatment of lipid disorders
NO20070176L (no) Nye fluorglykosidderivater av pyrazoler, medikamenter inneholdende disse forbindelsene og anvendelse derav
NO20052914L (no) Terapeutiske forbindelser
NO20085066L (no) 4,5-difenyl-pyrimidinyl-aminosubstituerte karboksylsyrer, fremgangsmate for deres fremstilling og anvendelse derav som medikamenter
UA66852C2 (uk) Похідні та аналоги 3-арилпропіонової кислоти, спосіб їх отримання, фармацевтична композиція (варіанти) та спосіб профілактики та/або лікування асоційованих з резистентністю до інсуліну клінічних станів
NO20054852L (no) GFAT inhibitorer
UA84156C2 (ru) Фторозамещённая омега-карбоксиарилдифенилмочевина для лечения и профилактики болезней и состояний
NO20085064L (no) 4,5-difenyl-pyrimidinyl-oksy eller -merkaptosubstituerte karboksylsyrer, fremgangsmate for deres fremstilling og anvendelse derav som medikamenter
NO20065904L (no) Terapeutiske forbindelser
TNSN06030A1 (en) Substituted thiazole-benzoisothiazole dioxide derivavites, method for the production thereof and use of the same
NO20050134L (no) Difenylazetidioner substituert med syregrupper, fremgangsmate for fremstilling av disse, medikamenter inneholdende disse forbindelser og deres anvendelse
NO20076425L (no) Fremgangsmater for behandling av drug-resistent cancer
NO20045222L (no) Benzosyrederivater som modulatorer av PPAR alfa og gamma
NO20044531L (no) Imidazolinylmetyl-aralkylsulfonamider, blandinger omfattende slike, fremgangsmate for fremstilling av slike, slike forbindelser som medikament samt anvendelse av slike forbindelser for fremstilling av medikamenter for behandling av sykdom
AU2001246999A1 (en) New neurokinin antagonists for use as medicaments
NO20053809L (no) Diarylmetylindenpiperidinderivater,fremgangsmate for fremstilling derav, og anvendelse derav
WO2007104933A8 (fr) Composés chimiques
NO20054389L (no) Cyckloalkyl-substituerte alkansyrederivater, fremgangsmate for fremstilling og anvendelse derav som legemiddel
EP1666472A4 (fr) Derive d'acide phenylacetique, ainsi que procede de production et utilisation de celui-ci
AU2001244999A1 (en) Naphthamide neurokinin antagonists for use as medicaments

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application