NO20061950L - Benzoimidazolforbindelser - Google Patents

Benzoimidazolforbindelser

Info

Publication number
NO20061950L
NO20061950L NO20061950A NO20061950A NO20061950L NO 20061950 L NO20061950 L NO 20061950L NO 20061950 A NO20061950 A NO 20061950A NO 20061950 A NO20061950 A NO 20061950A NO 20061950 L NO20061950 L NO 20061950L
Authority
NO
Norway
Prior art keywords
benzoimidazolforbindelser
receptor
leukocyte
inflammation
modulating
Prior art date
Application number
NO20061950A
Other languages
English (en)
Norwegian (no)
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20061950L publication Critical patent/NO20061950L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
    • C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
    • C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
    • C04B35/632—Organic additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/53—Hinge
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2318/00—Antibody mimetics or scaffolds
    • C07K2318/10—Immunoglobulin or domain(s) thereof as scaffolds for inserted non-Ig peptide sequences, e.g. for vaccination purposes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Manufacturing & Machinery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ceramic Engineering (AREA)
  • Structural Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO20061950A 2003-09-30 2006-05-02 Benzoimidazolforbindelser NO20061950L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50723603P 2003-09-30 2003-09-30
PCT/US2004/031855 WO2005044807A2 (fr) 2003-09-30 2004-09-29 Composes de benzoimidazole

Publications (1)

Publication Number Publication Date
NO20061950L true NO20061950L (no) 2006-06-29

Family

ID=38952593

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20061950A NO20061950L (no) 2003-09-30 2006-05-02 Benzoimidazolforbindelser

Country Status (21)

Country Link
US (10) US7432378B2 (fr)
EP (1) EP1673348B1 (fr)
JP (1) JP2007508011A (fr)
KR (1) KR20060097024A (fr)
CN (1) CN1886380B (fr)
AR (1) AR045955A1 (fr)
AT (1) ATE427303T1 (fr)
AU (1) AU2004286933B2 (fr)
BR (1) BRPI0414918A (fr)
CA (1) CA2540704A1 (fr)
DE (1) DE602004020364D1 (fr)
ES (1) ES2323178T3 (fr)
HR (1) HRP20060126A2 (fr)
IL (1) IL174677A0 (fr)
NO (1) NO20061950L (fr)
NZ (1) NZ546259A (fr)
PT (1) PT1673348E (fr)
RU (1) RU2006110561A (fr)
TW (1) TW200526637A (fr)
WO (1) WO2005044807A2 (fr)
ZA (1) ZA200603411B (fr)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1673348B1 (fr) * 2003-09-30 2009-04-01 Janssen Pharmaceutica N.V. Composes de benzoimidazole
EA011242B1 (ru) 2004-03-25 2009-02-27 Янссен Фармацевтика Н.В. Производные имидазола
EP1824832B1 (fr) 2004-06-30 2011-04-27 Janssen Pharmaceutica NV Ethers benzimidazole a substitution aryle et imidazopyridine, comme anticancereux
AU2006251163C1 (en) 2005-05-26 2012-07-12 Janssen Sciences Ireland Uc Process for preparing 4-[(1,6-dihydro-6-oxo-2-pyrimidinyl)amino benzonitrile
EP1910290A2 (fr) * 2005-06-30 2008-04-16 Prosidion Limited Agonistes de gpcr
US8334290B2 (en) 2005-10-31 2012-12-18 Merck Sharp & Dohme Corp. CETP inhibitors
GB0525068D0 (en) 2005-12-08 2006-01-18 Novartis Ag Organic compounds
EP1961745A1 (fr) * 2005-12-12 2008-08-27 Ono Pharmaceutical Co., Ltd. Compose heterocyclique bicyclique
WO2007117399A2 (fr) * 2006-03-31 2007-10-18 Janssen Pharmaceutica N.V. Benzoimidazol-2-yl pyrimidines et pyrazines modulatrices du récepteur de l'histamine h4
WO2007117400A2 (fr) * 2006-03-31 2007-10-18 Janssen Pharmaceutica N.V. Benzoimidazol-2-yl pyridines modulatrices du récepteur de l'histamine h4
WO2007120690A2 (fr) * 2006-04-10 2007-10-25 Janssen Pharmaceutica N.V. Thérapie combinée avec des antagonistes des récepteurs histaminiques h1r et h4r pour le traitement du prurit
FR2903311B1 (fr) * 2006-07-10 2012-06-15 Centre Nat Rech Scient Utilisation de ligands du recepteur h4 de l'histamine pour proteger les progeniteurs hematopoietiques contre la toxicite hematologique des agents chimiotherapeutiques
US7985745B2 (en) 2006-10-02 2011-07-26 Abbott Laboratories Method for pain treatment
WO2009079001A1 (fr) 2007-12-18 2009-06-25 Janssen Pharmaceutica N.V. Imidazoles bicycliques substitué par hétéroaryle constituant des modulateurs du récepteur de l'histamine h4
EP2077263A1 (fr) 2008-01-02 2009-07-08 Vereniging voor christelijk hoger onderwijs, wetenschappelijk onderzoek en patiëntenzorg Quinazolines et composés hétérocycliques rélatifs et leur utilisation thérapeutique
BRPI0915526A2 (pt) 2008-06-12 2016-01-26 Janssen Pharmaceutica Nv uso de um antagonista da histamina h4 para o tratamento de aderências pós-operatórias
US9371311B2 (en) 2008-06-30 2016-06-21 Janssen Pharmaceutica Nv Benzoimidazol-2-yl pyrimidine derivatives
SG192446A1 (en) 2008-06-30 2013-08-30 Janssen Pharmaceutica Nv Process for the preparation of benzoimidazol-2-yl pyrimidine derivatives
WO2010036908A1 (fr) * 2008-09-26 2010-04-01 Eisai R & D Management Co., Ltd. Utilisation de composés benzoxazole dans le traitement du paludisme
WO2010036905A1 (fr) * 2008-09-26 2010-04-01 Eisai R & D Management Co., Ltd. Composés benzoxazole et procédés d'utilisation
EP2201982A1 (fr) 2008-12-24 2010-06-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Antagonistes du récepteur H4 de l'histamine pour le traitement de troubles vestibulaires
US8349852B2 (en) 2009-01-13 2013-01-08 Novartis Ag Quinazolinone derivatives useful as vanilloid antagonists
IT1395137B1 (it) * 2009-08-05 2012-09-05 Spider Biotech S R L Nuovi peptidi antipatogeni
TW201111378A (en) 2009-09-11 2011-04-01 Bayer Schering Pharma Ag Substituted (heteroarylmethyl) thiohydantoins
AR080056A1 (es) 2010-02-01 2012-03-07 Novartis Ag Derivados de ciclohexil-amida como antagonistas de los receptores de crf
WO2011092290A1 (fr) 2010-02-01 2011-08-04 Novartis Ag Dérivés de pyrazolo[5,1-b] utilisés en tant qu'antagonistes du récepteur de crf-1
EP2531490B1 (fr) 2010-02-02 2014-10-15 Novartis AG Dérivés de cyclohexylamide à titre d'antagonistes du récepteur crf
EP2447263A1 (fr) * 2010-09-27 2012-05-02 Bioprojet Dérivés de benzazole en tant que ligands du récepteur H4
AR086554A1 (es) 2011-05-27 2014-01-08 Novartis Ag Derivados de la piperidina 3-espirociclica como agonistas de receptores de la ghrelina
DE102011122420B4 (de) 2011-12-24 2016-07-28 Volkswagen Aktiengesellschaft Verfahren zur Feststellung der Spannungsfreiheit in einem elektrischen Hochvolt-System und ein elektrisches Hochvolt-System
JP2015525202A (ja) 2012-05-03 2015-09-03 ノバルティス アーゲー グレリン受容体アゴニストとしての２，７−ジアザ−スピロ［４，５］デカ−７−イル誘導体のｌ−リンゴ酸塩およびその結晶形態
EP2671870A1 (fr) * 2012-06-05 2013-12-11 Bioprojet Nouveaux dérivés d'éther (aza)benzhydryle, leur procédé de préparation et leur utilisation en tant que ligands du récepteur H4 pour applications thérapeutiques
EP3378476A1 (fr) 2012-06-08 2018-09-26 Sensorion Inhibiteurs du récepteur h4 destinés au traitement des acouphènes
PT2964229T (pt) 2013-03-06 2020-03-23 Janssen Pharmaceutica Nv Moduladores de piridina benzimidazol-2-ilo do recetor h4 de histamina
KR102779499B1 (ko) * 2018-05-22 2025-03-12 니혼노야쿠가부시키가이샤 벤즈이미다졸 화합물 또는 그의 염류 및 해당 화합물을 함유하는 농원예용 살충 살진드기제 그리고 그의 사용 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2587029B1 (fr) * 1985-09-11 1987-10-30 Synthelabo Derives de benzimidazole, leur preparation et leur application en therapeutique
JP2000516611A (ja) * 1996-08-14 2000-12-12 ワーナー―ランバート・コンパニー Ｍｃｐ―１アンタゴニストとしての２―フェニルベンズイミダゾール誘導体
DE59911249D1 (de) * 1998-11-03 2005-01-13 Abbott Gmbh & Co Kg Substituierte 2-phenylbenzimidazole, deren herstellung und anwendung
DE19920936A1 (de) * 1999-05-07 2000-11-09 Basf Ag Heterozyklisch substituierte Benzimidazole, deren Herstellung und Anwendung
WO2002072548A2 (fr) * 2001-03-09 2002-09-19 Ortho-Mcneil Pharmaceutical, Inc. Composes heterocycliques
EP1673348B1 (fr) * 2003-09-30 2009-04-01 Janssen Pharmaceutica N.V. Composes de benzoimidazole

Also Published As

Publication number Publication date
ATE427303T1 (de) 2009-04-15
WO2005044807A3 (fr) 2005-08-11
ES2323178T3 (es) 2009-07-08
US7723527B2 (en) 2010-05-25
DE602004020364D1 (de) 2009-05-14
US7432378B2 (en) 2008-10-07
TW200526637A (en) 2005-08-16
US20090281307A1 (en) 2009-11-12
US7723359B2 (en) 2010-05-25
US20090275748A1 (en) 2009-11-05
CA2540704A1 (fr) 2005-05-19
HRP20060126A2 (en) 2008-05-31
US7705143B2 (en) 2010-04-27
US7723526B2 (en) 2010-05-25
NZ546259A (en) 2009-05-31
US20090247508A1 (en) 2009-10-01
EP1673348B1 (fr) 2009-04-01
AU2004286933B2 (en) 2010-11-18
US20050070550A1 (en) 2005-03-31
AR045955A1 (es) 2005-11-16
IL174677A0 (en) 2006-08-20
US20090264647A1 (en) 2009-10-22
EP1673348A2 (fr) 2006-06-28
PT1673348E (pt) 2009-05-11
US20090264645A1 (en) 2009-10-22
US7662966B2 (en) 2010-02-16
US20090270613A1 (en) 2009-10-29
ZA200603411B (en) 2007-07-25
US20090264646A1 (en) 2009-10-22
KR20060097024A (ko) 2006-09-13
US7705149B2 (en) 2010-04-27
BRPI0414918A (pt) 2006-11-07
JP2007508011A (ja) 2007-04-05
RU2006110561A (ru) 2007-10-10
CN1886380A (zh) 2006-12-27
US20090270611A1 (en) 2009-10-29
AU2004286933A1 (en) 2005-05-19
US20090270366A1 (en) 2009-10-29
CN1886380B (zh) 2010-12-22
WO2005044807A2 (fr) 2005-05-19

Similar Documents

Publication Publication Date Title
NO20061950L (no) Benzoimidazolforbindelser
BRPI0516727A (pt) métodos para tratar um linfoma positivo em cd30 , para inibir o crescimento de uma célula que expressa cd30, e para tratar ou prevenir uma doença
SV2009003227A (es) Composiciones de inhibidores de chk 1 ref. x-17672
DE60333746D1 (de) Thienylverbindungen
IS7721A (is) Píperidín-pýrídasón og þalasón sem PDE4 hemlar
SG157365A1 (en) Compositions and methods for treating neoplastic diseases
ATE525377T1 (de) Imidazoä1,5-aüpyrazine als inhibitoren von tyrosinkinase
ATE484508T1 (de) Furylverbindungen
NO20082191L (no) Forbindelser
NO20020351L (no) Anordning omfattende ekspanderbare bistabile rördeler, samt fremgangsmåter for deres bruk i brönnboringer
YU5503A (sh) Nesteroidni supresori zapaljenja
NO20052887D0 (no) Pyridazinonderivater som GSK-3Beta inhibitorer.
TW200617605A (en) Compositions and processes for immersion lithography
DE60313872D1 (de) Pyrazoloä1,5-aüpyrimidine als hemmstoffe cyclin-abhängiger kinasen
MX2009009290A (es) Compuestos activos en ppar.
NO20052529L (no) Forbindelse og sammensetning, og anvendelse av samme
NO20044995L (no) Heterosykliske forbindelser
NO20025811L (no) Forbindelser som er effektive som beta-2-adrenoreseptor- agonister så vel som PDE4-inhibitorer
NO20075275L (no) Nye forbindelser
AU2003230969A1 (en) Compositions for treating hyperemia
AU2003297318A1 (en) Methods and compositions for treating cancer using 15986, 2188, 20743, 9148, 9151, 9791, 44252, 14184, 42461, 8204, 7970, 25552, 21657, 26492, 2411, 15088, 1905, 28899, 63380, 33935, 10480, 12686, 25501, 17694, 15701, 53062, 49908, 21612, 38949, 6216, 46863, 9235, 2201, 6985, 9883, 12238, 18057, 21617, 39228, 49928, 54476.
NO20045025L (no) Nye forbindelser
NO20075140L (no) Fremgangsmater og preparater for modulering av vaskulaer integritet
DK1485059T3 (da) Topisk dapson til behandling af akne
NO20055830L (no) Proglitazpnsalter, sa som pioglitazonsulfat og farmasoytiske sammensetnnger og fremgangsmater ved bruk av de samme

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application