NO308411B1 - <beta>,<beta>'-dihydroksy-meso-substituerte kloriner, isobakteriokloriner, bakteriokloriner og fremgangsmÕter for fremstilling av disse fra <beta>,<beta>'-usubstituerte tetrapyrrol- makrocykler - Google Patents

<beta>,<beta>'-dihydroksy-meso-substituerte kloriner, isobakteriokloriner, bakteriokloriner og fremgangsmÕter for fremstilling av disse fra <beta>,<beta>'-usubstituerte tetrapyrrol- makrocykler

Info

Publication number
NO308411B1
NO308411B1 NO971952A NO971952A NO308411B1 NO 308411 B1 NO308411 B1 NO 308411B1 NO 971952 A NO971952 A NO 971952A NO 971952 A NO971952 A NO 971952A NO 308411 B1 NO308411 B1 NO 308411B1
Authority
NO
Norway
Prior art keywords
beta
substituted
meso
dihydroxy
isobacteriochlorines
Prior art date
Application number
NO971952A
Other languages
English (en)
Norwegian (no)
Other versions
NO971952D0 (no
NO971952L (no
Inventor
David Dolphin
Christian Bruckner
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ British Columbia filed Critical Univ British Columbia
Publication of NO971952D0 publication Critical patent/NO971952D0/no
Publication of NO971952L publication Critical patent/NO971952L/no
Publication of NO308411B1 publication Critical patent/NO308411B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0485—Porphyrins, texaphyrins wherein the nitrogen atoms forming the central ring system complex the radioactive metal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Radiology & Medical Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
NO971952A 1994-10-26 1997-04-25 <beta>,<beta>'-dihydroksy-meso-substituerte kloriner, isobakteriokloriner, bakteriokloriner og fremgangsmÕter for fremstilling av disse fra <beta>,<beta>'-usubstituerte tetrapyrrol- makrocykler NO308411B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/329,577 US5648485A (en) 1994-10-26 1994-10-26 β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
PCT/CA1995/000602 WO1996013504A1 (en) 1994-10-26 1995-10-25 β,β'-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, BACTERIOCHLORINS, AND METHODS FOR MAKING THE SAME FROM β,β'-UNSUBSTITUTED TETRAPYRROLIC MACROCYCLES

Publications (3)

Publication Number Publication Date
NO971952D0 NO971952D0 (no) 1997-04-25
NO971952L NO971952L (no) 1997-04-25
NO308411B1 true NO308411B1 (no) 2000-09-11

Family

ID=23286058

Family Applications (1)

Application Number Title Priority Date Filing Date
NO971952A NO308411B1 (no) 1994-10-26 1997-04-25 <beta>,<beta>'-dihydroksy-meso-substituerte kloriner, isobakteriokloriner, bakteriokloriner og fremgangsmÕter for fremstilling av disse fra <beta>,<beta>'-usubstituerte tetrapyrrol- makrocykler

Country Status (20)

Country Link
US (2) US5648485A (de)
EP (1) EP0804439B1 (de)
JP (2) JP3228296B2 (de)
KR (1) KR970707129A (de)
CN (1) CN1043143C (de)
AT (1) ATE250064T1 (de)
AU (1) AU704971B2 (de)
CA (1) CA2199399C (de)
CZ (1) CZ294496B6 (de)
DE (1) DE69531795T2 (de)
DK (1) DK0804439T3 (de)
ES (1) ES2208701T3 (de)
FI (1) FI971734A0 (de)
HU (1) HU221102B1 (de)
NO (1) NO308411B1 (de)
NZ (1) NZ294203A (de)
PL (1) PL182239B1 (de)
PT (1) PT804439E (de)
TW (1) TW301648B (de)
WO (1) WO1996013504A1 (de)

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US5648485A (en) * 1994-10-26 1997-07-15 University Of British Columbia β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
GB9610967D0 (en) 1996-05-24 1996-07-31 Cambridge Antibody Tech Specific binding members,materials and methods
EP0973383A4 (de) * 1997-01-21 2001-08-22 American Nat Red Cross Intrazelluläre und extrazelluläre dekontamination von vollblut und blutbestandteilen mit amphiphilen phenothiazin-5-ium farbstoffen und licht
US6444194B1 (en) 1997-02-14 2002-09-03 Miravant Pharmaceuticals, Inc. Indium photosensitizers for PDT
FR2760841B1 (fr) * 1997-03-12 1999-04-16 Commissariat Energie Atomique Determination par resonance magnetique nucleaire de la configuration absolue d'amino-acides ou de leur derives et complexes metalliques de porphyrines chirales utilisables pour cette determination
DE19814405C2 (de) 1998-03-31 2000-03-02 Schastak Astrid Porphyrine und ihre Verwendung als Photosensitizer
US20030176663A1 (en) * 1998-05-11 2003-09-18 Eidgenossische Technische Hochscule Specific binding molecules for scintigraphy
HUP0104608A3 (en) 1998-10-20 2002-11-28 Procter & Gamble Tenzide mixture comprising modified alkylbenzene sulfonates and laundry detergents containing thereof, and process for preparation of the mixture and for use of the detergents
US6583096B1 (en) 1998-10-20 2003-06-24 The Procter & Gamble Company Laundry detergents comprising modified alkylbenzene sulfonates
US7022843B1 (en) 1999-04-14 2006-04-04 The University Of British Columbia β,β′-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
WO2000061584A1 (en) * 1999-04-14 2000-10-19 The University Of British Columbia IMPROVED β,β,-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, AND BACTERIOCHLORINS
US20020022032A1 (en) * 1999-04-23 2002-02-21 Curry Patrick Mark Immuno-adjuvant PDT treatment of metastatic tumors
US6376483B1 (en) 1999-05-27 2002-04-23 Miravant Pharmaceuticals, Inc. Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production
US7897140B2 (en) * 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
JP2003524018A (ja) 2000-02-24 2003-08-12 アイトゲネーシシェ テクニシェ ホッホシューレ チューリッヒ フィブロネクチンのｅｄ‐ｂドメインに特異的な抗体、前記抗体を含む複合体、および血管形成を検出および治療するためのその使用
CA2408323C (en) 2000-05-08 2012-06-12 The University Of British Columbia Drug delivery systems for photodynamic therapy
CA2408332C (en) 2000-05-08 2011-02-15 The University Of British Columbia Supports for photosensitizer formulations
US6559374B2 (en) * 2000-07-21 2003-05-06 North Carolina State University Trans beta substituted chlorins and methods of making and using the same
CN1246333C (zh) * 2000-09-07 2006-03-22 舍林股份公司 EDb－纤粘连蛋白结构域(II)的受体
WO2002020536A1 (fr) * 2000-09-08 2002-03-14 San-Ei Gen F.F.I.,Inc. Derives de tetraphenyl-bacteriochlore et compositions les contenant
US20050090481A1 (en) * 2001-11-09 2005-04-28 Qlt Inc Compositions comprising a photosensitizer and a skin-penetration enhancer and their use in photodynamic treatment
EP1517684B1 (de) 2002-06-27 2009-07-22 Health Research, Inc. Fluorinierte chlorin und bacteriochlorin photosensitizer für fotodynamische therapie
WO2004005289A2 (en) * 2002-07-02 2004-01-15 Health Research, Inc. Efficient synthesis of pyropheophorbide a and its derivatives
EP1594875A4 (de) * 2003-01-16 2007-07-11 Technomart Co Ltd Porphyrinderivate
US7057100B2 (en) * 2003-06-26 2006-06-06 The J.C. Robinson Seed Co. Inbred corn line W23129
GB0323358D0 (en) * 2003-10-06 2003-11-05 Green Grass Design Ltd Novel compounds and processes
JP4635493B2 (ja) * 2003-10-09 2011-02-23 日本製紙株式会社 ダル調塗工紙
GB2408265A (en) * 2003-11-21 2005-05-25 Univ Sheffield Water-soluble hyperbranched polymer porphyrins
US6995260B2 (en) * 2004-05-20 2006-02-07 Brookhaven Science Associates, Llc Carboranylporphyrins and uses thereof
WO2006089122A2 (en) 2005-02-18 2006-08-24 North Carolina State University De novo synthesis of bacteriochlorins
WO2007064841A2 (en) * 2005-11-30 2007-06-07 North Carolina State University Porphyrinic compounds for use in flow cytometry
WO2009038659A2 (en) * 2007-09-14 2009-03-26 Health Research, Inc. Organically modified silica nanoparticles with covalently incorporated photosensitizers for drug delivery in photodynamic therapy
US8253725B2 (en) * 2007-12-28 2012-08-28 St. Jude Medical, Atrial Fibrillation Division, Inc. Method and system for generating surface models of geometric structures
US20120034155A1 (en) * 2010-08-03 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Artificial cells
ES2707228T3 (es) * 2008-09-18 2019-04-03 Biolitec Unternehmensbeteiligungs Ii Ag Nuevo método y aplicación de porfirinas y clorinas asimétricamente meso-sustituidas para TFD
GB0819594D0 (en) 2008-10-24 2008-12-03 Univ Coimbrra Process
US9226917B2 (en) 2008-12-16 2016-01-05 Valeant Pharmaceuticals International, Inc. Photodynamic therapy for conditions of the eye
US9211283B2 (en) 2009-12-11 2015-12-15 Biolitec Pharma Marketing Ltd Nanoparticle carrier systems based on human serum albumin for photodynamic therapy
JP5858932B2 (ja) 2010-02-04 2016-02-10 モルフォテック， インコーポレイテッド クロロトキシンポリペプチドおよびコンジュゲートならびにその使用
JP2013532664A (ja) * 2010-07-22 2013-08-19 セラムオプテック ゲゼルシャフト ミット ベシュレンクテル ハフツング ＰＤＴのためのβ−官能化ジヒドロキシ−クロリンの用途
WO2013003507A1 (en) 2011-06-27 2013-01-03 Morphotek, Inc. Multifunctional agents
JP6181059B2 (ja) 2011-10-25 2017-08-16 メモリアル スローン−ケタリング キャンサー センター 前立腺がんのための診断薬、予後判定薬、および治療薬としてのフリーｐｓａ抗体
AU2013334102B2 (en) 2012-10-26 2018-08-16 Memorial Sloan-Kettering Cancer Center Modulators of resistant androgen receptor
CA2907356C (en) 2013-03-15 2022-07-12 Sherri Ann MCFARLAND Metal-based coordination complexes as photodynamic compounds and their use
PL3087182T3 (pl) 2013-12-23 2019-11-29 Memorial Sloan Kettering Cancer Center Sposoby i kompozycje do leczenia raka wykorzystujące środki oparte na kwasie peptydonukleinowym
TWI474536B (zh) 2014-07-01 2015-02-21 Nat Univ Chung Hsing 紫質光敏染料化合物以及染料敏化太陽能電池
EP3201201B1 (de) 2014-09-30 2022-01-26 biolitec unternehmensbeteiligungs II AG Spezifisch meso-substituierte porphyrine und chlorine für photodynamische therapie
RU2615770C1 (ru) * 2015-12-21 2017-04-11 Общество с ограниченной ответственностью "Пермская химическая компания" Борированные производные фторированных бактериохлоринов и их металлокомплексов, обладающие противоопухолевой активностью
CA3045921C (en) * 2016-12-05 2024-06-04 Salt And Light Pharmaceuticals Pty. Ltd. Photodynamic therapeutic compounds and photodynamic methods of treatment

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648485A (en) * 1994-10-26 1997-07-15 University Of British Columbia β, β-dihydroxy meso-substituted chlorins, isobacteriochlorins, and bacteriochlorins
US6376483B1 (en) * 1999-05-27 2002-04-23 Miravant Pharmaceuticals, Inc. Bacteriochlorins and bacteriopurpurins useful as photoselective compounds for photodynamic therapy and a process for their production

Also Published As

Publication number Publication date
FI971734L (fi) 1997-04-23
CA2199399C (en) 2004-02-24
CN1043143C (zh) 1999-04-28
NZ294203A (en) 1998-12-23
PT804439E (pt) 2004-02-27
JP3228296B2 (ja) 2001-11-12
US5831088A (en) 1998-11-03
CZ294496B6 (cs) 2005-01-12
PL182239B1 (pl) 2001-11-30
ATE250064T1 (de) 2003-10-15
CZ115597A3 (en) 1997-09-17
EP0804439B1 (de) 2003-09-17
AU704971B2 (en) 1999-05-13
JPH10507766A (ja) 1998-07-28
TW301648B (de) 1997-04-01
CA2199399A1 (en) 1996-05-09
HU221102B1 (en) 2002-08-28
FI971734A7 (fi) 1997-04-23
JP2001294589A (ja) 2001-10-23
ES2208701T3 (es) 2004-06-16
NO971952D0 (no) 1997-04-25
MX9703013A (es) 1997-07-31
HUT77008A (hu) 1998-03-02
PL319907A1 (en) 1997-09-01
WO1996013504A1 (en) 1996-05-09
FI971734A0 (fi) 1997-04-23
NO971952L (no) 1997-04-25
DE69531795T2 (de) 2004-08-05
US5648485A (en) 1997-07-15
AU3695195A (en) 1996-05-23
DK0804439T3 (da) 2004-02-02
KR970707129A (ko) 1997-12-01
EP0804439A1 (de) 1997-11-05
CN1161697A (zh) 1997-10-08
DE69531795D1 (de) 2003-10-23

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