PL2595960T3 - Salt and solvates of a tetrahydroisoquinoline derivative - Google Patents

Salt and solvates of a tetrahydroisoquinoline derivative

Info

Publication number
PL2595960T3
PL2595960T3 PL11740973.0T PL11740973T PL2595960T3 PL 2595960 T3 PL2595960 T3 PL 2595960T3 PL 11740973 T PL11740973 T PL 11740973T PL 2595960 T3 PL2595960 T3 PL 2595960T3
Authority
PL
Poland
Prior art keywords
solvates
salt
tetrahydroisoquinoline derivative
tetrahydroisoquinoline
derivative
Prior art date
Application number
PL11740973.0T
Other languages
Polish (pl)
Inventor
Thomas David Mccarthy
Peter Michael Kelly
Craig James Stewart Boyle
Alexander Redvers Eberlin
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL2595960T3 publication Critical patent/PL2595960T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
PL11740973.0T 2010-07-21 2011-07-21 Salt and solvates of a tetrahydroisoquinoline derivative PL2595960T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36636710P 2010-07-21 2010-07-21

Publications (1)

Publication Number Publication Date
PL2595960T3 true PL2595960T3 (en) 2016-09-30

Family

ID=44386640

Family Applications (1)

Application Number Title Priority Date Filing Date
PL11740973.0T PL2595960T3 (en) 2010-07-21 2011-07-21 Salt and solvates of a tetrahydroisoquinoline derivative

Country Status (20)

Country Link
US (3) US8614227B2 (en)
EP (2) EP2595960B1 (en)
JP (3) JP5948326B2 (en)
CN (2) CN105777636A (en)
AU (3) AU2011281381B2 (en)
CA (1) CA2803699C (en)
DK (1) DK2595960T3 (en)
ES (1) ES2570135T3 (en)
HK (1) HK1224290A1 (en)
HR (1) HRP20160540T1 (en)
HU (1) HUE028620T2 (en)
ME (1) ME02407B (en)
NZ (2) NZ605444A (en)
PL (1) PL2595960T3 (en)
PT (1) PT2595960E (en)
RS (1) RS54789B1 (en)
SI (1) SI2595960T1 (en)
SM (1) SMT201600171B (en)
WO (1) WO2012010843A1 (en)
ZA (1) ZA201300169B (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011281381B2 (en) * 2010-07-21 2015-07-16 Novartis Ag Salt and solvates of a tetrahydroisoquinoline derivative
US9320530B2 (en) * 2013-03-13 2016-04-26 The Spectranetics Corporation Assisted cutting balloon
ES2883155T3 (en) * 2013-07-08 2021-12-07 Novartis Ag Heterocyclic compounds and methods for their use
JP6667551B2 (en) 2015-01-13 2020-03-18 ノバルティス アーゲー Pyrrolidine derivatives as angiotensin II type 2 antagonists
US10308628B2 (en) 2015-03-12 2019-06-04 Novartis Ag Heterocyclic compounds and methods for their use
CN106478502B (en) * 2015-08-29 2021-04-27 上海翰森生物医药科技有限公司 1,2,3,4-Tetrahydroisoquinoline derivative, its preparation method and application
WO2018001997A1 (en) 2016-06-27 2018-01-04 Ratiopharm Gmbh Crystalline calcium salt of (s)-2-(diphenylacetyl)-1,2,3,4-tetrahydro-6-methoxy-5-(phenylmethoxy)-3-isoquinoline carboxylic acid
JP2019514862A (en) * 2017-03-23 2019-06-06 ノバルティス アーゲー Anhydrous crystalline form of sodium (S) -2- (diphenylacetyl) -1,2,3,4-tetrahydro-6-methoxy-5- (phenylmethoxy) -3-isoquinolinecarboxylate
PT3620454T (en) * 2017-06-09 2021-09-10 Shandong Danhong Pharmaceutical Co Ltd Carboxylic acid derivative as at2r receptor antagonist
JP2021531749A (en) 2018-07-12 2021-11-25 コデクシス， インコーポレイテッド Manipulated Phenylalanine Ammonia Riase Polypeptide
WO2020012266A1 (en) 2018-07-12 2020-01-16 Novartis Ag Biocatalytic synthesis of olodanrigan (ema401) from 3-(2-(benzyloxy)-3-methoxyphenyl)propenoic acid with phenylalanine ammonia lyase
CN111620816B (en) * 2020-05-27 2023-06-02 上海赛默罗生物科技有限公司 Propeller derivatives, preparation method, pharmaceutical composition and application thereof
GB202100352D0 (en) * 2021-01-12 2021-02-24 Balticgruppen Bio Ab New methods
CN115901740A (en) * 2022-11-18 2023-04-04 南京工业大学 Dopamine detection reagent and application based on Pictet-Spengler reaction, detection method of dopamine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5246943A (en) * 1992-05-19 1993-09-21 Warner-Lambert Company Substituted 1,2,3,4-tetahydroisoquinolines with angiotensin II receptor antagonist properties
US5236934A (en) 1992-08-26 1993-08-17 E. I. Du Pont De Nemours And Company 1,2,3,4-tetrahydroisoquinolines useful in the treatment of CNS disorders
CA2318778A1 (en) * 1998-02-25 1999-09-02 Merck & Co., Inc. Method for decreasing qt dispersion or inhibiting the progression of qt dispersion with an angiotensin ii receptor antagonist
WO2006066361A1 (en) * 2004-12-24 2006-06-29 The University Of Queensland Method of treatment or prophylaxis
CA2866540A1 (en) * 2006-03-20 2007-09-27 Spinifex Pharmaceuticals Pty Ltd. Method of treatment or prophylaxis of inflammatory pain
NZ601383A (en) * 2010-01-19 2014-07-25 Spinifex Pharm Pty Ltd Methods and compositions for improved nerve conduction velocity
AU2011281381B2 (en) * 2010-07-21 2015-07-16 Novartis Ag Salt and solvates of a tetrahydroisoquinoline derivative

Also Published As

Publication number Publication date
US20140080865A1 (en) 2014-03-20
US8614227B2 (en) 2013-12-24
AU2015238774A1 (en) 2015-10-29
JP2013531057A (en) 2013-08-01
EP3081557A1 (en) 2016-10-19
HRP20160540T1 (en) 2016-06-17
HK1224290A1 (en) 2017-08-18
US20150105422A1 (en) 2015-04-16
ZA201300169B (en) 2016-03-30
PT2595960E (en) 2016-06-02
CN105777636A (en) 2016-07-20
ES2570135T3 (en) 2016-05-17
CN103003244B (en) 2016-04-20
CA2803699A1 (en) 2012-01-26
US8927575B2 (en) 2015-01-06
WO2012010843A1 (en) 2012-01-26
NZ708529A (en) 2016-11-25
US20120022101A1 (en) 2012-01-26
JP2017214415A (en) 2017-12-07
EP2595960B1 (en) 2016-02-24
JP5948326B2 (en) 2016-07-06
AU2011281381A1 (en) 2013-01-10
HUE028620T2 (en) 2016-12-28
CN103003244A (en) 2013-03-27
US9162985B2 (en) 2015-10-20
AU2017203236A1 (en) 2017-06-08
ME02407B (en) 2016-09-20
DK2595960T3 (en) 2016-05-09
SI2595960T1 (en) 2016-06-30
EP2595960A1 (en) 2013-05-29
RS54789B1 (en) 2016-10-31
SMT201600171B (en) 2016-07-01
JP2016164178A (en) 2016-09-08
AU2011281381B2 (en) 2015-07-16
NZ605444A (en) 2015-06-26
CA2803699C (en) 2016-05-31

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