PL3466933T3 - Triazole do regulacji wewnątrzkomórkowej homeostazy wapnia - Google Patents

Triazole do regulacji wewnątrzkomórkowej homeostazy wapnia

Info

Publication number
PL3466933T3
PL3466933T3 PL17735609T PL17735609T PL3466933T3 PL 3466933 T3 PL3466933 T3 PL 3466933T3 PL 17735609 T PL17735609 T PL 17735609T PL 17735609 T PL17735609 T PL 17735609T PL 3466933 T3 PL3466933 T3 PL 3466933T3
Authority
PL
Poland
Prior art keywords
triazoles
intracellular calcium
calcium homeostasis
regulating intracellular
regulating
Prior art date
Application number
PL17735609T
Other languages
English (en)
Inventor
Ainara Vallejo Illarramendi
Adolfo José LÓPEZ DE MUNAIN ARREGI
Pablo Ferrón Celma
Jesús María AIZPURUA IPARRAGUIRRE
Aitziber IRASTORZA EPELDE
José Ignacio MIRANDA MURUA
Iván TORAL OJEDA
Garazi ALDANONDO ARISTIZABAL
Original Assignee
Universidad Del País Vasco/Euskal Herriko Unibertsitatea
Administración General De La Comunidad Autónoma De Euskadi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad Del País Vasco/Euskal Herriko Unibertsitatea, Administración General De La Comunidad Autónoma De Euskadi filed Critical Universidad Del País Vasco/Euskal Herriko Unibertsitatea
Publication of PL3466933T3 publication Critical patent/PL3466933T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41921,2,3-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/041,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0029Parenteral nutrition; Parenteral nutrition compositions as drug carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL17735609T 2016-05-24 2017-05-23 Triazole do regulacji wewnątrzkomórkowej homeostazy wapnia PL3466933T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES201630670A ES2643856B1 (es) 2016-05-24 2016-05-24 Triazoles para la regulación de la homeostasis de calcio intracelular
PCT/ES2017/070344 WO2017203083A1 (es) 2016-05-24 2017-05-23 Triazoles para la regulación de la homeostasis de calcio intracelular
EP17735609.4A EP3466933B1 (en) 2016-05-24 2017-05-23 Triazoles for regulating intracellular calcium homeostasis

Publications (1)

Publication Number Publication Date
PL3466933T3 true PL3466933T3 (pl) 2021-06-14

Family

ID=59285262

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17735609T PL3466933T3 (pl) 2016-05-24 2017-05-23 Triazole do regulacji wewnątrzkomórkowej homeostazy wapnia

Country Status (17)

Country Link
US (1) US11377427B2 (pl)
EP (1) EP3466933B1 (pl)
JP (1) JP6983875B2 (pl)
CN (1) CN109563056B (pl)
AU (1) AU2017270485B2 (pl)
CA (1) CA3025436C (pl)
CL (1) CL2018003318A1 (pl)
DK (1) DK3466933T3 (pl)
ES (2) ES2643856B1 (pl)
HR (1) HRP20210211T1 (pl)
HU (1) HUE053371T2 (pl)
IL (1) IL263168B2 (pl)
MX (1) MX381545B (pl)
PL (1) PL3466933T3 (pl)
PT (1) PT3466933T (pl)
RU (1) RU2753509C2 (pl)
WO (1) WO2017203083A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI759301B (zh) 2016-05-24 2022-04-01 美商安美基公司 聚乙二醇化卡非佐米化合物
WO2021162054A1 (ja) * 2020-02-10 2021-08-19 学校法人順天堂 2型リアノジン受容体活性抑制剤
JP2025520705A (ja) * 2022-06-23 2025-07-03 ミラムーン、ファーマ、ソシエダッド、リミターダ 眼疾患治療において使用するためのトリアゾール類

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JP2703408B2 (ja) 1990-12-28 1998-01-26 麒麟麦酒株式会社 1,4‐ベンゾチアゼピン誘導体
US6709599B1 (en) * 1999-10-27 2004-03-23 Rwe Nukem Corporation Waste water treatment system with slip stream
US20040229781A1 (en) 2000-05-10 2004-11-18 Marks Andrew Robert Compounds and methods for treating and preventing exercise-induced cardiac arrhythmias
US8022058B2 (en) 2000-05-10 2011-09-20 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
AU2005247473A1 (en) 2004-05-25 2005-12-08 Metabolex, Inc. Substituted triazoles as modulators of PPAR and methods of their preparation
CA2583267A1 (en) 2004-10-12 2006-04-27 Amgen Inc. Novel b1 bradykinin receptor antagonists
US7515666B2 (en) 2005-07-29 2009-04-07 International Business Machines Corporation Method for dynamically changing the frequency of clock signals
US7704990B2 (en) 2005-08-25 2010-04-27 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US8802726B2 (en) 2006-02-03 2014-08-12 Nicox S.A. Use of nitrooxyderivative of drug for the treatment of muscular dystrophies
MX2008010187A (es) 2006-02-10 2008-10-31 Summit Corp Plc Tratamiento de distrofia muscular de duchenne.
US8703804B2 (en) 2006-03-26 2014-04-22 Uti Limited Partnership Ryanodine receptor inhibitors and methods relating thereto
WO2008060332A2 (en) 2006-06-02 2008-05-22 The Trustees Of Columbia University In The City Of New York Methods for treating or reducing muscle fatigue
WO2008144483A2 (en) 2007-05-18 2008-11-27 Armgo Pharma, Inc. Agents for treating disorders involving modulation of ryanodine receptors
GB0715087D0 (en) 2007-08-03 2007-09-12 Summit Corp Plc Drug combinations for the treatment of duchenne muscular dystrophy
GB0821307D0 (en) 2008-11-21 2008-12-31 Summit Corp Plc Compounds for treatment of duchenne muscular dystrophy
WO2012019071A1 (en) 2010-08-06 2012-02-09 The Trustees Of Columbia University In The City Of New York Methods of preventing and treating sarcopenia
WO2012037105A1 (en) 2010-09-14 2012-03-22 The Trustees Of Columbia University In The City Of New York Methods of treating, ameliorating or preventing stress-induced neuronal disorders and diseases
CA2830866A1 (en) * 2011-04-08 2012-10-11 Pfizer Inc. Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents
WO2013085890A1 (en) 2011-12-06 2013-06-13 Glaxo Group Limited Therapeutic methods
EP2828249B1 (en) * 2012-03-23 2018-10-10 The Regents of The University of California Premature-termination-codons readthrough compounds
EP2708535A1 (en) * 2012-05-11 2014-03-19 Les Laboratoires Servier Agents for treating disorders involving modulation of ryanodine receptors
WO2014205414A1 (en) * 2013-06-21 2014-12-24 The Regents Of The University Of California Expanded therapeutic potential in nitroheteroaryl antimicrobials
EP2857388A1 (de) * 2013-10-01 2015-04-08 Grünenthal GmbH Sulfon-haltige Azole
CA2928235A1 (en) 2013-10-25 2015-04-30 Bush, Ernest D. Methods for treatment of muscular dystrophies
US20160083380A1 (en) 2013-12-16 2016-03-24 Cadila Healthcare Limited Oximino derivatives for the treatment of dyslipidemia
WO2016057656A1 (en) * 2014-10-08 2016-04-14 Mitobridge, Inc. Ppar-delta agonists for use for treating mitochondrial, vascular, muscular, and demyelinating diseases

Also Published As

Publication number Publication date
RU2018141584A3 (pl) 2020-07-27
CL2018003318A1 (es) 2019-04-12
CA3025436C (en) 2024-02-20
ES2853701T3 (es) 2021-09-17
HUE053371T2 (hu) 2021-06-28
HRP20210211T1 (hr) 2021-03-19
JP6983875B2 (ja) 2021-12-17
CA3025436A1 (en) 2017-11-30
MX381545B (es) 2025-03-12
CN109563056A (zh) 2019-04-02
AU2017270485A1 (en) 2018-12-13
IL263168B1 (en) 2023-05-01
EP3466933A1 (en) 2019-04-10
RU2753509C2 (ru) 2021-08-17
ES2643856B1 (es) 2018-08-03
WO2017203083A1 (es) 2017-11-30
RU2018141584A (ru) 2020-06-25
DK3466933T3 (da) 2021-01-11
ES2643856A1 (es) 2017-11-24
AU2017270485B2 (en) 2021-02-25
CN109563056B (zh) 2022-08-16
US20200317625A1 (en) 2020-10-08
IL263168A (en) 2018-12-31
MX2018014414A (es) 2019-04-22
IL263168B2 (en) 2023-09-01
PT3466933T (pt) 2021-02-23
JP2019520423A (ja) 2019-07-18
US11377427B2 (en) 2022-07-05
EP3466933B1 (en) 2020-12-02

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