PL430456A1 - Chitosan-based hydrogel skin substitute and method of its production - Google Patents

Chitosan-based hydrogel skin substitute and method of its production

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Publication number
PL430456A1
PL430456A1 PL430456A PL43045619A PL430456A1 PL 430456 A1 PL430456 A1 PL 430456A1 PL 430456 A PL430456 A PL 430456A PL 43045619 A PL43045619 A PL 43045619A PL 430456 A1 PL430456 A1 PL 430456A1
Authority
PL
Poland
Prior art keywords
chitosan
skin substitute
acetic acid
production
based hydrogel
Prior art date
Application number
PL430456A
Other languages
Polish (pl)
Other versions
PL243151B1 (en
Inventor
Agata Przekora-Kuśmierz
Vladyslav Vivcharenko
Paulina Kazimierczak
Michał Wójcik
Original Assignee
Uniwersytet Medyczny W Lublinie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uniwersytet Medyczny W Lublinie filed Critical Uniwersytet Medyczny W Lublinie
Priority to PL430456A priority Critical patent/PL243151B1/en
Publication of PL430456A1 publication Critical patent/PL430456A1/en
Publication of PL243151B1 publication Critical patent/PL243151B1/en

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  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)

Abstract

Przedmiotem zgłoszenia jest hydrożelowy substytut skóry na bazie chitozanu charakteryzuje się tym, że stanowi go chitozan i kurdlan (bakteryjny ß-1,3-D-glukan) rozprowadzone w 0,5 - 3% wodnym roztworze kwasu octowego, przy czym proporcje wagowe stałych komponentów wynoszą odpowiednio 0,5 - 4% (w/v) chitozanu i 2 - 15% (w/v) kurdlanu w odniesieniu do kwasu octowego. Zgłoszenie obejmuje też sposób wytwarzania hydrożelowego bioaktywnego substytutu skóry według wynalazku polega na rozprowadzeniu polisacharydów w roztworze kwasu octowego, a następnie ich żelowaniu w wysokiej temperaturze, neutralizacji w NaOH, przepłukaniu w wodzie dejonizowanej i suszeniu na powietrzu w temperaturze pokojowej.The subject of the application is a hydrogel skin substitute based on chitosan, characterized by the fact that it is chitosan and curdlan (bacterial ß-1,3-D-glucan) dispersed in 0.5 - 3% aqueous acetic acid solution, the weight proportion of solid components are 0.5 - 4% (w / v) chitosan and 2 - 15% (w / v) curdlan with respect to acetic acid, respectively. The application also covers a method for the preparation of the hydrogel bioactive skin substitute according to the invention, which consists in spreading the polysaccharides in acetic acid solution, followed by gelatinization at high temperature, neutralization in NaOH, rinsing in deionized water and air drying at room temperature.

PL430456A 2019-07-01 2019-07-01 Chitosan-based hydrogel skin substitute and method of its production PL243151B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL430456A PL243151B1 (en) 2019-07-01 2019-07-01 Chitosan-based hydrogel skin substitute and method of its production

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL430456A PL243151B1 (en) 2019-07-01 2019-07-01 Chitosan-based hydrogel skin substitute and method of its production

Publications (2)

Publication Number Publication Date
PL430456A1 true PL430456A1 (en) 2021-01-11
PL243151B1 PL243151B1 (en) 2023-07-10

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Family Applications (1)

Application Number Title Priority Date Filing Date
PL430456A PL243151B1 (en) 2019-07-01 2019-07-01 Chitosan-based hydrogel skin substitute and method of its production

Country Status (1)

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PL (1) PL243151B1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113769157A (en) * 2021-09-01 2021-12-10 西北大学 A kind of injectable hydrogel and preparation method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113769157A (en) * 2021-09-01 2021-12-10 西北大学 A kind of injectable hydrogel and preparation method thereof

Also Published As

Publication number Publication date
PL243151B1 (en) 2023-07-10

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