PT3038609T - Modificadores de resposta de células t citotóxicas - Google Patents
Modificadores de resposta de células t citotóxicasInfo
- Publication number
- PT3038609T PT3038609T PT14761596T PT14761596T PT3038609T PT 3038609 T PT3038609 T PT 3038609T PT 14761596 T PT14761596 T PT 14761596T PT 14761596 T PT14761596 T PT 14761596T PT 3038609 T PT3038609 T PT 3038609T
- Authority
- PT
- Portugal
- Prior art keywords
- cytotoxic
- cell response
- response modifiers
- modifiers
- cell
- Prior art date
Links
- 230000005867 T cell response Effects 0.000 title 1
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 title 1
- 239000003607 modifier Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Transplantation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361870421P | 2013-08-27 | 2013-08-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3038609T true PT3038609T (pt) | 2021-10-01 |
Family
ID=51494273
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT14761596T PT3038609T (pt) | 2013-08-27 | 2014-08-27 | Modificadores de resposta de células t citotóxicas |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US9994854B2 (pt) |
| EP (1) | EP3038609B1 (pt) |
| JP (1) | JP2016535060A (pt) |
| CN (1) | CN105517542B9 (pt) |
| CA (1) | CA2918568A1 (pt) |
| DK (1) | DK3038609T3 (pt) |
| ES (1) | ES2891081T3 (pt) |
| PT (1) | PT3038609T (pt) |
| WO (1) | WO2015028515A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3538549A1 (en) * | 2016-11-10 | 2019-09-18 | iOmx Therapeutics AG | Or10h1 antigen binding proteins and uses thereof |
| EP3321280B8 (en) * | 2016-11-10 | 2021-03-10 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Immune modulators for reducing immune-resistance in melanoma and other proliferative diseases |
| JP2021521248A (ja) * | 2018-04-16 | 2021-08-26 | ラ ホヤ インスティテュート フォア アラージー アンド イムノロジー | 嗅覚受容体活性を標的とすることによる免疫応答のモジュレート |
| JP2022526340A (ja) * | 2019-03-25 | 2022-05-24 | マックス-デルブリュック-ツェントルム フューア モレキュラーレ メディツィン イン デア ヘルムホルツ-ゲマインシャフト | Ebag9を阻害することによる細胞溶解性t細胞の活性の増強 |
| WO2021024742A1 (ja) * | 2019-08-06 | 2021-02-11 | 国立大学法人筑波大学 | 細胞傷害アッセイ方法 |
| KR102631623B1 (ko) * | 2021-04-16 | 2024-02-02 | 경북대학교 산학협력단 | 젖산에 의한 종양 관련 대식세포의 m2형 분화 및 종양 성장의 억제를 위한 후각수용체의 용도 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0507672D0 (en) * | 2005-04-15 | 2005-05-25 | Barnaba Vincenzo | Adjuvant |
| DE102006008074B4 (de) * | 2006-02-22 | 2013-08-14 | RUHR-UNIVERSITäT BOCHUM | Behandlung von Krebs mit Geruchsrezeptor-Liganden |
| EP1881080A1 (en) * | 2006-07-18 | 2008-01-23 | Institut Gustave Roussy | Toll like receptor 4 dysfunction and the biological applications thereof |
| WO2008022104A1 (en) * | 2006-08-15 | 2008-02-21 | Hutchison Medipharma Enterprises Limited | Costunolide derivatives |
| US9764012B2 (en) * | 2009-04-01 | 2017-09-19 | University Of Miami | Vaccine compositions and methods of use thereof |
| US8673578B2 (en) * | 2009-10-27 | 2014-03-18 | Deutsches Institut für Ernahrungsforschung Potsdam-Rehbrücke | Methods of identifying antagonists of the hTAS2R46 bitter taste receptor |
| US9044492B2 (en) * | 2011-02-04 | 2015-06-02 | Cellectis Sa | Method for modulating the efficiency of double-strand break-induced mutagenesis |
-
2014
- 2014-08-27 EP EP14761596.7A patent/EP3038609B1/en active Active
- 2014-08-27 JP JP2016537284A patent/JP2016535060A/ja not_active Ceased
- 2014-08-27 CN CN201480047185.XA patent/CN105517542B9/zh active Active
- 2014-08-27 WO PCT/EP2014/068183 patent/WO2015028515A1/en not_active Ceased
- 2014-08-27 CA CA2918568A patent/CA2918568A1/en not_active Abandoned
- 2014-08-27 PT PT14761596T patent/PT3038609T/pt unknown
- 2014-08-27 ES ES14761596T patent/ES2891081T3/es active Active
- 2014-08-27 DK DK14761596.7T patent/DK3038609T3/da active
- 2014-08-27 US US14/914,585 patent/US9994854B2/en active Active
-
2018
- 2018-06-08 US US16/004,077 patent/US20180298388A1/en not_active Abandoned
-
2019
- 2019-09-06 US US16/563,348 patent/US11802285B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3038609B1 (en) | 2021-07-28 |
| DK3038609T3 (da) | 2021-09-13 |
| JP2016535060A (ja) | 2016-11-10 |
| US11802285B2 (en) | 2023-10-31 |
| CA2918568A1 (en) | 2015-03-05 |
| US20200002706A1 (en) | 2020-01-02 |
| CN105517542A (zh) | 2016-04-20 |
| EP3038609A1 (en) | 2016-07-06 |
| US20180298388A1 (en) | 2018-10-18 |
| US9994854B2 (en) | 2018-06-12 |
| WO2015028515A1 (en) | 2015-03-05 |
| CN105517542B (zh) | 2021-12-07 |
| HK1225614A1 (en) | 2017-09-15 |
| US20160201066A1 (en) | 2016-07-14 |
| ES2891081T3 (es) | 2022-01-26 |
| CN105517542B9 (zh) | 2022-01-11 |
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