PT3394272T - Composições e métodos para direcionamento eficiente de transgenes - Google Patents

Composições e métodos para direcionamento eficiente de transgenes

Info

Publication number
PT3394272T
PT3394272T PT168799344T PT16879934T PT3394272T PT 3394272 T PT3394272 T PT 3394272T PT 168799344 T PT168799344 T PT 168799344T PT 16879934 T PT16879934 T PT 16879934T PT 3394272 T PT3394272 T PT 3394272T
Authority
PT
Portugal
Prior art keywords
transgenes
compositions
methods
efficient targeting
targeting
Prior art date
Application number
PT168799344T
Other languages
English (en)
Original Assignee
Monsanto Technology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Technology Llc filed Critical Monsanto Technology Llc
Publication of PT3394272T publication Critical patent/PT3394272T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/001Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8274Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8201Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
    • C12N15/8202Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8221Transit peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04Plant cells or tissues
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0069Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y103/00Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/03Oxidoreductases acting on the CH-CH group of donors (1.3) with oxygen as acceptor (1.3.3)
    • C12Y103/03004Protoporphyrinogen oxidase (1.3.3.4)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/08Fusion polypeptide containing a localisation/targetting motif containing a chloroplast localisation signal

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Physiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
PT168799344T 2015-12-21 2016-12-19 Composições e métodos para direcionamento eficiente de transgenes PT3394272T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562270180P 2015-12-21 2015-12-21
US201662364715P 2016-07-20 2016-07-20

Publications (1)

Publication Number Publication Date
PT3394272T true PT3394272T (pt) 2023-04-11

Family

ID=59065936

Family Applications (1)

Application Number Title Priority Date Filing Date
PT168799344T PT3394272T (pt) 2015-12-21 2016-12-19 Composições e métodos para direcionamento eficiente de transgenes

Country Status (25)

Country Link
US (1) US10563220B2 (pt)
EP (2) EP3394272B1 (pt)
JP (2) JP6961611B2 (pt)
KR (1) KR102847177B1 (pt)
CN (2) CN116355928A (pt)
AU (2) AU2016377487B2 (pt)
BR (1) BR102016029899A2 (pt)
CA (1) CA2950803A1 (pt)
CO (1) CO2018007568A2 (pt)
DK (1) DK3394272T5 (pt)
EC (1) ECSP18054745A (pt)
ES (1) ES2941913T3 (pt)
HR (1) HRP20230311T1 (pt)
HU (1) HUE061632T2 (pt)
MX (1) MX385151B (pt)
PE (2) PE20240226A1 (pt)
PH (1) PH12018501317B1 (pt)
PL (1) PL3394272T3 (pt)
PT (1) PT3394272T (pt)
RS (1) RS64091B1 (pt)
RU (1) RU2751238C2 (pt)
UA (1) UA126554C2 (pt)
UY (2) UY37040A (pt)
WO (1) WO2017112589A1 (pt)
ZA (1) ZA201803723B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3331997T5 (da) 2015-08-03 2024-10-07 Monsanto Technology Llc Fremgangsmåder og sammensætninger til herbicidtolerans i planter
US10378023B2 (en) 2015-09-01 2019-08-13 Monsanto Technology Llc Methods and compositions for herbicide tolerance in plants
PE20190838A1 (es) 2016-07-29 2019-06-17 Monsanto Technology Llc Metodos y composiciones para la expresion genica en plantas
AU2017301976B2 (en) 2016-07-29 2022-04-07 Basf Se Method for controlling PPO resistant weeds
CA3026528A1 (en) * 2017-12-15 2019-06-15 Monsanto Technology Llc Methods and compositions for ppo herbicide tolerance
US11758907B2 (en) 2017-12-20 2023-09-19 Sumitomo Chemical Company, Limited Method for controlling harmful organisms in crops
CA3057917A1 (en) * 2018-10-16 2020-04-16 Monsanto Technology Llc Brassica event mon94100 and methods of use thereof
CN115336534A (zh) * 2021-05-12 2022-11-15 北京大北农生物技术有限公司 原卟啉原氧化酶的用途
WO2023044364A1 (en) 2021-09-15 2023-03-23 Enko Chem, Inc. Protoporphyrinogen oxidase inhibitors
AU2023206316A1 (en) 2022-01-14 2024-08-29 Enko Chem, Inc. Protoporphyrinogen oxidase inhibitors
JP2025542247A (ja) * 2022-12-20 2025-12-25 モンサント テクノロジー エルエルシー トランスジェニックトウモロコシ事象Zm_CSM63715ならびにその検出及び使用方法
EP4698556A1 (en) 2023-04-19 2026-02-25 Syngenta Crop Protection AG Herbicide resistant plants
GB202314578D0 (en) 2023-09-22 2023-11-08 Univ Manchester Methods of producing homoplasmic modified plants or parts thereof
WO2025153595A1 (en) 2024-01-17 2025-07-24 Basf Se Plants having increased tolerance to herbicides

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939602A (en) * 1995-06-06 1999-08-17 Novartis Finance Corporation DNA molecules encoding plant protoporphyrinogen oxidase and inhibitor-resistant mutants thereof
US5659114A (en) 1996-05-10 1997-08-19 Asgrow Seed Company Soybean cultivar 88154622393
US6252148B1 (en) 1999-12-06 2001-06-26 Holden's Foundation Seeds Llc Inbred corn line LH244
US20090100536A1 (en) * 2001-12-04 2009-04-16 Monsanto Company Transgenic plants with enhanced agronomic traits
US7847156B2 (en) 2003-10-20 2010-12-07 Cropdesign N.V. Plants having improved growth characteristics and methods for making the same
US7166779B1 (en) 2003-03-07 2007-01-23 Monsanto Technology, L.L.C. Plants and seeds of variety I294213
US20060048240A1 (en) 2004-04-01 2006-03-02 Nickolai Alexandrov Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
US6930228B2 (en) 2003-10-16 2005-08-16 D&Pl Technology Holding Company, Llc Cotton cultivar DP 393
CA2636196C (en) * 2006-01-06 2018-12-11 Rijk Zwaan Zaadteelt En Zaadhandel B.V. Screening method for selecting plants that show a reduced wound-induced surface discolouration
US7855326B2 (en) 2006-06-06 2010-12-21 Monsanto Technology Llc Methods for weed control using plants having dicamba-degrading enzymatic activity
WO2007146703A2 (en) 2006-06-06 2007-12-21 Ud Technology Corporation Process for coating a shear thickening fluid onto a material
WO2007146678A1 (en) 2006-06-06 2007-12-21 Monsanto Technology Llc Method for selection of transformed cells
US7884262B2 (en) 2006-06-06 2011-02-08 Monsanto Technology Llc Modified DMO enzyme and methods of its use
AR063316A1 (es) 2006-10-16 2009-01-21 Monsanto Technology Llc Metodos y composiciones para mejorar el estado sanitario de plantas
US7939721B2 (en) 2006-10-25 2011-05-10 Monsanto Technology Llc Cropping systems for managing weeds
US7838729B2 (en) 2007-02-26 2010-11-23 Monsanto Technology Llc Chloroplast transit peptides for efficient targeting of DMO and uses thereof
US7700846B2 (en) 2008-05-07 2010-04-20 Monsanto Technology Llc Soybean variety D5245143
EP2797406B1 (en) * 2011-12-30 2020-01-08 Dow AgroSciences LLC Construct and method for synthetic bidirectional plant promoter ubi1
US10041087B2 (en) 2012-06-19 2018-08-07 BASF Agro B.V. Plants having increased tolerance to herbicides
AR091489A1 (es) * 2012-06-19 2015-02-11 Basf Se Plantas que tienen una mayor tolerancia a herbicidas inhibidores de la protoporfirinogeno oxidasa (ppo)
EP3033426A4 (en) 2013-08-12 2017-08-02 BASF Agro B.V. Plants having increased tolerance to herbicides
CN106133142B (zh) * 2014-03-28 2020-10-30 孟山都技术公司 具有抗鞘翅目昆虫活性的杀虫毒素蛋白
DK3331997T5 (da) 2015-08-03 2024-10-07 Monsanto Technology Llc Fremgangsmåder og sammensætninger til herbicidtolerans i planter
US10378023B2 (en) 2015-09-01 2019-08-13 Monsanto Technology Llc Methods and compositions for herbicide tolerance in plants
PE20190838A1 (es) 2016-07-29 2019-06-17 Monsanto Technology Llc Metodos y composiciones para la expresion genica en plantas
CA3026528A1 (en) 2017-12-15 2019-06-15 Monsanto Technology Llc Methods and compositions for ppo herbicide tolerance

Also Published As

Publication number Publication date
ES2941913T3 (es) 2023-05-26
ZA201803723B (en) 2019-07-31
AU2020281170A1 (en) 2021-02-04
WO2017112589A1 (en) 2017-06-29
EP4219729A3 (en) 2023-09-27
AU2020281170B2 (en) 2021-05-20
BR102016029899A2 (pt) 2017-06-27
DK3394272T3 (da) 2023-04-03
RS64091B1 (sr) 2023-04-28
PE20240226A1 (es) 2024-02-16
AU2016377487A1 (en) 2018-06-28
US20170175131A1 (en) 2017-06-22
UY40405A (es) 2023-09-29
EP4219729A2 (en) 2023-08-02
UA126554C2 (uk) 2022-11-02
AU2016377487B2 (en) 2020-12-24
HRP20230311T1 (hr) 2023-05-12
CN108463554B (zh) 2023-04-18
PL3394272T3 (pl) 2023-05-08
RU2018124597A3 (pt) 2020-05-28
JP2022009102A (ja) 2022-01-14
JP6961611B2 (ja) 2021-11-05
PH12018501317A1 (en) 2019-02-18
PE20181540A1 (es) 2018-09-26
EP3394272A4 (en) 2019-07-31
EP3394272B1 (en) 2023-01-11
HUE061632T2 (hu) 2023-07-28
CN108463554A (zh) 2018-08-28
PH12018501317B1 (en) 2023-08-30
UY37040A (es) 2017-07-31
CO2018007568A2 (es) 2018-07-31
JP7312805B2 (ja) 2023-07-21
MX2018007705A (es) 2018-11-09
CA2950803A1 (en) 2017-06-21
RU2018124597A (ru) 2020-01-23
EP3394272A1 (en) 2018-10-31
KR20180089518A (ko) 2018-08-08
DK3394272T5 (da) 2024-09-30
RU2751238C2 (ru) 2021-07-12
ECSP18054745A (es) 2018-08-31
US10563220B2 (en) 2020-02-18
AU2020281170C1 (en) 2021-11-18
CN116355928A (zh) 2023-06-30
MX385151B (es) 2025-03-14
KR102847177B1 (ko) 2025-08-20
JP2019500060A (ja) 2019-01-10

Similar Documents

Publication Publication Date Title
IL320861B1 (en) Preparations and methods for internalizing enzymes
ZA201803723B (en) Compositions and methods for efficient targeting of transgenes
IL254811A0 (en) Hahaha
IL249637A0 (en) Methods and compositions for targeted genetic modifications and methods of use
ZA201801511B (en) Flavonoid compositions and methods of use
GB2546350B (en) Compositions and methods
SG10202109655VA (en) Compositions and methods for immunooncology
GB2535253B (en) Compositions and methods
IL252966B (en) Formulations and methods for antibodies targeting bmp6
GB201718876D0 (en) Antithrombin-heparin compositions and methods
PL3349743T3 (pl) Sposoby i kompozycje do hamowania oddziaływania dcn1-ubc12
IL255998A (en) Preparations and methods for suppressing the expression of the hif2alpha strain
SG11201803284YA (en) Novel method of use and compositions
PT3113774T (pt) Composições de grapiprant e métodos de utilização das mesmas
GB201512996D0 (en) Compositions and methods
GB201514413D0 (en) Compositions and methods
GB201402915D0 (en) Compositions and methods
IL256261B (en) Hide1 compositions and methods
GB201522554D0 (en) Methods and compositions
GB201518167D0 (en) Methods and compositions
GB201514415D0 (en) Compositions and methods
GB201419559D0 (en) Therapeutic compositions and methods
GB201403212D0 (en) Compositions and methods