PT3560937T - Métodos de preparação de agentes de imagem por tep direcionados para amep marcado no 18f'' e seus métodos de diagnóstico - Google Patents

Métodos de preparação de agentes de imagem por tep direcionados para amep marcado no 18f'' e seus métodos de diagnóstico

Info

Publication number
PT3560937T
PT3560937T PT191797588T PT19179758T PT3560937T PT 3560937 T PT3560937 T PT 3560937T PT 191797588 T PT191797588 T PT 191797588T PT 19179758 T PT19179758 T PT 19179758T PT 3560937 T PT3560937 T PT 3560937T
Authority
PT
Portugal
Prior art keywords
imaging agents
pet imaging
labeled psma
targeted pet
targeted
Prior art date
Application number
PT191797588T
Other languages
English (en)
Original Assignee
Cancer Targeted Tech Llc
Univ Washington State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Targeted Tech Llc, Univ Washington State filed Critical Cancer Targeted Tech Llc
Publication of PT3560937T publication Critical patent/PT3560937T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0489Phosphates or phosphonates, e.g. bone-seeking phosphonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0402Organic compounds carboxylic acid carriers, fatty acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/22Amides of acids of phosphorus
    • C07F9/24Esteramides
    • C07F9/2404Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/22Amides of acids of phosphorus
    • C07F9/24Esteramides
    • C07F9/2404Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2416Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of cycloaliphatic alcohols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/22Amides of acids of phosphorus
    • C07F9/24Esteramides
    • C07F9/2454Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2458Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT191797588T 2013-03-15 2014-03-14 Métodos de preparação de agentes de imagem por tep direcionados para amep marcado no 18f'' e seus métodos de diagnóstico PT3560937T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361798108P 2013-03-15 2013-03-15

Publications (1)

Publication Number Publication Date
PT3560937T true PT3560937T (pt) 2023-02-13

Family

ID=50639969

Family Applications (2)

Application Number Title Priority Date Filing Date
PT191797588T PT3560937T (pt) 2013-03-15 2014-03-14 Métodos de preparação de agentes de imagem por tep direcionados para amep marcado no 18f'' e seus métodos de diagnóstico
PT14721640T PT2970345T (pt) 2013-03-15 2014-03-14 Agentes de formação de imagem por tep sobre o amep marcado no 18f

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT14721640T PT2970345T (pt) 2013-03-15 2014-03-14 Agentes de formação de imagem por tep sobre o amep marcado no 18f

Country Status (17)

Country Link
US (3) US11554183B2 (pt)
EP (3) EP4180438A1 (pt)
CN (2) CN105308056B (pt)
AU (2) AU2014228233B2 (pt)
CA (1) CA2903131C (pt)
DK (2) DK2970345T3 (pt)
ES (2) ES2743433T3 (pt)
FI (1) FI3560937T3 (pt)
HR (2) HRP20230109T1 (pt)
HU (2) HUE046194T2 (pt)
LT (2) LT3560937T (pt)
PL (2) PL3560937T3 (pt)
PT (2) PT3560937T (pt)
RS (1) RS64011B1 (pt)
SI (2) SI2970345T1 (pt)
SM (1) SMT202300035T1 (pt)
WO (1) WO2014143736A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017027870A1 (en) * 2015-08-13 2017-02-16 The Johns Hopkins University Triazole conjugated ureas, thioureas, carbamates, and "reversed" carbamates for psma-targeted imaging agents and uses thereof
BR112019002560B1 (pt) * 2016-08-10 2022-08-16 Cancer Targeted Technology Llc Composto, composição farmacêutica, seus usos e método de preparação do mesmo
CN110418604B (zh) 2017-03-22 2023-04-18 赛佛欧普手术有限公司 用于检测电生理诱发电位变化的医疗系统和方法
US11629201B2 (en) 2017-05-24 2023-04-18 ITM Isotope Technologies Munich SE PSMA-binding agents and uses thereof
WO2018233798A1 (en) 2017-06-20 2018-12-27 ITM Isotopen Technologien München AG Novel psma-binding agents and uses thereof
WO2020108753A1 (en) 2018-11-28 2020-06-04 ITM Isotopen Technologien München AG Novel tumor antigen binding agents and uses thereof
WO2020224780A1 (en) 2019-05-08 2020-11-12 ITM Isotopen Technologien München AG Para-aminohippuric acid (pah) as a renal protective substance
WO2021046233A1 (en) 2019-09-03 2021-03-11 Cancer Targeted Technology Llc Chelate-containing psma inhibitors
WO2022096103A1 (en) 2020-11-05 2022-05-12 ITM Isotopen Technologien München AG Combination of para-aminohippuric acid (pah) and radiolabeled complexes for treating cancer
WO2022111800A1 (en) 2020-11-25 2022-06-02 Itm Solucin Gmbh Stable formulations for radionuclide complexes
US20240181092A1 (en) 2021-04-02 2024-06-06 Novartis Ag Diagnostic methods of prostate cancer
AU2024324648A1 (en) 2023-08-14 2026-02-26 Cancer Targeted Technology Llc Psma binding ligand-linker conjugates and methods for use thereof
WO2026027442A1 (en) 2024-08-01 2026-02-05 Novartis Ag Synthesis of a precursor of radiopharmaceutical products

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009532338A (ja) 2006-03-14 2009-09-10 キャンサー ターゲテッド テクノロジー エルエルシー Psmaのペプチド模倣体阻害剤、それらを含む化合物、およびそれらの使用方法
JP5603074B2 (ja) * 2006-09-08 2014-10-08 ピラマル イメージング ソシエテ アノニム 18f標識物質のための化合物と方法
RU2494096C2 (ru) * 2008-08-01 2013-09-27 Дзе Джонс Хопкинс Юниверсити Агенты, связывающиеся с psma, и их применение
WO2012064914A2 (en) 2010-11-12 2012-05-18 Washington State University Research Foundation Peptidomimetic inhibitors of psma
WO2012174136A1 (en) * 2011-06-15 2012-12-20 Cancer Targeted Technology Llc Chelated psma inhibitors
CN102757296B (zh) * 2012-04-10 2014-11-19 中国科学院上海应用物理研究所 一种对化合物进行[18f]标记的方法
WO2013173583A1 (en) * 2012-05-16 2013-11-21 Cancer Targeted Technology, Llc Psma inhibitors
WO2013173630A1 (en) * 2012-05-16 2013-11-21 Cancer Targeted Technology, Llc Formulation of radiopharmaceuticals containing multiple acidic groups

Also Published As

Publication number Publication date
FI3560937T3 (fi) 2023-02-28
HRP20230109T1 (hr) 2023-04-28
AU2014228233B2 (en) 2019-02-28
CN105308056B (zh) 2018-03-20
HUE061402T2 (hu) 2023-06-28
RS64011B1 (sr) 2023-03-31
DK2970345T3 (da) 2019-08-26
SI2970345T1 (sl) 2019-11-29
PL2970345T3 (pl) 2019-12-31
ES2937955T3 (es) 2023-04-03
US11554183B2 (en) 2023-01-17
AU2014228233A1 (en) 2015-09-17
CA2903131A1 (en) 2014-09-18
EP3560937A1 (en) 2019-10-30
PL3560937T3 (pl) 2023-03-27
CN108558939A (zh) 2018-09-21
US20250375542A1 (en) 2025-12-11
SI3560937T1 (sl) 2023-04-28
EP2970345A1 (en) 2016-01-20
CN108558939B (zh) 2021-08-24
CN105308056A (zh) 2016-02-03
DK3560937T3 (da) 2023-02-13
EP3560937B1 (en) 2022-12-28
AU2019203610A1 (en) 2019-06-13
US20230144322A1 (en) 2023-05-11
AU2019203610B2 (en) 2021-02-04
HRP20191482T1 (hr) 2019-11-15
CA2903131C (en) 2021-11-23
SMT202300035T1 (it) 2023-05-12
LT3560937T (lt) 2023-03-27
EP4180438A1 (en) 2023-05-17
PT2970345T (pt) 2019-09-06
LT2970345T (lt) 2019-09-25
EP2970345B1 (en) 2019-06-19
US20160030605A1 (en) 2016-02-04
HUE046194T2 (hu) 2020-02-28
WO2014143736A1 (en) 2014-09-18
ES2743433T3 (es) 2020-02-19

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