PT3819302T - Oligossacárido de sulfato de condroitina fucosilado, método de preparação correspondente, sua composição e sua utilização - Google Patents
Oligossacárido de sulfato de condroitina fucosilado, método de preparação correspondente, sua composição e sua utilizaçãoInfo
- Publication number
- PT3819302T PT3819302T PT198383473T PT19838347T PT3819302T PT 3819302 T PT3819302 T PT 3819302T PT 198383473 T PT198383473 T PT 198383473T PT 19838347 T PT19838347 T PT 19838347T PT 3819302 T PT3819302 T PT 3819302T
- Authority
- PT
- Portugal
- Prior art keywords
- preparation
- composition
- chondroitin sulfate
- corresponding method
- sulfate oligosaccharide
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Polymers & Plastics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810778733 | 2018-07-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3819302T true PT3819302T (pt) | 2022-12-23 |
Family
ID=69163991
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT198383473T PT3819302T (pt) | 2018-07-16 | 2019-07-15 | Oligossacárido de sulfato de condroitina fucosilado, método de preparação correspondente, sua composição e sua utilização |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12421270B2 (pt) |
| EP (1) | EP3819302B1 (pt) |
| JP (1) | JP7166450B2 (pt) |
| CN (1) | CN110724209B (pt) |
| ES (1) | ES2934583T3 (pt) |
| PT (1) | PT3819302T (pt) |
| WO (1) | WO2020015612A1 (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111471120B (zh) * | 2020-06-16 | 2021-02-26 | 北京赫尔默技术有限公司 | 一种硫酸软骨素的制备方法及应用 |
| CN115381844B (zh) * | 2021-09-29 | 2024-03-22 | 北京大学 | 一种细菌荚膜寡糖衍生物及其制备方法、药物组合物和用途 |
| CN114990175B (zh) * | 2021-10-22 | 2023-03-31 | 岩唐生物科技(杭州)有限责任公司 | 一种岩藻糖衍生物的合成方法 |
| WO2025157248A1 (zh) * | 2024-01-26 | 2025-07-31 | 烟台东诚药业集团股份有限公司 | 一种岩藻糖基化硫酸软骨素寡糖衍生物及其应用 |
| CN119708287B (zh) * | 2024-11-28 | 2025-11-18 | 复旦大学 | 一种用于治疗心肌梗塞的化合物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101735336B (zh) | 2009-11-06 | 2012-07-18 | 深圳海王药业有限公司 | 低聚岩藻糖化糖胺聚糖及其制备方法 |
| CN104558070B (zh) | 2013-10-14 | 2017-10-24 | 北京大学 | 新芒果苷的化学合成方法及中间体化合物 |
| CN106467563B (zh) | 2015-08-21 | 2019-08-06 | 北京大学 | 硫酸软骨素四糖的合成方法及其中间体化合物 |
| JP6147322B2 (ja) * | 2015-10-01 | 2017-06-14 | ゼリアヘルスウエイ株式会社 | サーチュイン1活性化剤 |
| CN106349407A (zh) | 2016-08-29 | 2017-01-25 | 中国海洋大学 | 一种低分子量岩藻糖化硫酸软骨素及其制备方法和在制备抗特鲁索综合征的药物中的应用 |
| CN106645483B (zh) | 2016-12-26 | 2019-05-21 | 大连工业大学 | 一种定量检测海参多糖的方法 |
| CN108794653B (zh) * | 2017-05-05 | 2020-07-17 | 烟台东诚药业集团股份有限公司 | 岩藻糖基化硫酸软骨素寡糖糖簇及其制备方法 |
| CN107261147A (zh) * | 2017-05-29 | 2017-10-20 | 钟术光 | 一种稳定活体生物活性材料的组合物 |
| CN109912668B (zh) * | 2019-01-17 | 2022-06-14 | 中国科学院昆明植物研究所 | 岩藻糖化硫酸软骨素三糖的制备方法、中间体和用途 |
-
2019
- 2019-07-15 US US17/775,893 patent/US12421270B2/en active Active
- 2019-07-15 CN CN201910637636.XA patent/CN110724209B/zh active Active
- 2019-07-15 EP EP19838347.3A patent/EP3819302B1/en active Active
- 2019-07-15 ES ES19838347T patent/ES2934583T3/es active Active
- 2019-07-15 JP JP2021525352A patent/JP7166450B2/ja active Active
- 2019-07-15 WO PCT/CN2019/096033 patent/WO2020015612A1/zh not_active Ceased
- 2019-07-15 PT PT198383473T patent/PT3819302T/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2020015612A1 (zh) | 2020-01-23 |
| JP2021529877A (ja) | 2021-11-04 |
| JP7166450B2 (ja) | 2022-11-07 |
| EP3819302B1 (en) | 2022-10-19 |
| EP3819302A1 (en) | 2021-05-12 |
| CN110724209B (zh) | 2021-11-19 |
| ES2934583T3 (es) | 2023-02-23 |
| CN110724209A (zh) | 2020-01-24 |
| EP3819302A4 (en) | 2021-10-13 |
| US12421270B2 (en) | 2025-09-23 |
| US20230029252A1 (en) | 2023-01-26 |
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