PT71889A - Silymarin isolation from Silybum marianum oil expression residue - by extn. with ethyl acetate, defatting with petroleum ether, and work-up in aq. methanol - Google Patents

Silymarin isolation from Silybum marianum oil expression residue - by extn. with ethyl acetate, defatting with petroleum ether, and work-up in aq. methanol

Info

Publication number: PT71889A
Authority: PT; Portugal
Prior art keywords: residue; silymarin; meoh; extn; water
Prior art date: 1980-10-08

Application number

PT7188980A

Other languages

German (de)

English (en)

Other versions

PT71889B (de

Original Assignee

Madaus & Co Dr

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-10-08

Filing date

1980-10-08

Publication date

1980-11-01

1980-10-08 Application filed by Madaus & Co Dr filed Critical Madaus & Co Dr

1980-10-08 Priority to PT7188980A priority Critical patent/PT71889B/pt

1980-11-01 Publication of PT71889A publication Critical patent/PT71889A/pt

1981-09-03 Publication of PT71889B publication Critical patent/PT71889B/pt

Links

OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 title abstract 7
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 title abstract 6
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 title abstract 6
235000017700 silymarin Nutrition 0.000 title abstract 5
SEBFKMXJBCUCAI-UHFFFAOYSA-N NSC 227190 Natural products C1=C(O)C(OC)=CC(C2C(OC3=CC=C(C=C3O2)C2C(C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 SEBFKMXJBCUCAI-UHFFFAOYSA-N 0.000 title abstract 4
SEBFKMXJBCUCAI-HKTJVKLFSA-N silibinin Chemical compound C1=C(O)C(OC)=CC([C@@H]2[C@H](OC3=CC=C(C=C3O2)[C@@H]2[C@H](C(=O)C3=C(O)C=C(O)C=C3O2)O)CO)=C1 SEBFKMXJBCUCAI-HKTJVKLFSA-N 0.000 title abstract 4
229960004245 silymarin Drugs 0.000 title abstract 4
239000003208 petroleum Substances 0.000 title abstract 3
244000272459 Silybum marianum Species 0.000 title abstract 2
235000010841 Silybum marianum Nutrition 0.000 title abstract 2
238000002955 isolation Methods 0.000 title 1
238000010626 work up procedure Methods 0.000 title 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 4
150000001335 aliphatic alkanes Chemical class 0.000 abstract 1
150000001348 alkyl chlorides Chemical class 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
235000013399 edible fruits Nutrition 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000001553 hepatotropic effect Effects 0.000 abstract 1
230000000717 retained effect Effects 0.000 abstract 1
239000000725 suspension Substances 0.000 abstract 1

Landscapes

Medicines Containing Plant Substances (AREA)

PT7188980A 1980-10-08 1980-10-08 Verfahren zur gewinnung von silymarin aus pflanzen PT71889B (de)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
PT7188980A PT71889B (de)	1980-10-08	1980-10-08	Verfahren zur gewinnung von silymarin aus pflanzen

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PT7188980A PT71889B (de)	1980-10-08	1980-10-08	Verfahren zur gewinnung von silymarin aus pflanzen

Publications (2)

Publication Number	Publication Date
PT71889A true PT71889A (en)	1980-11-01
PT71889B PT71889B (de)	1981-09-03

Family

ID=20082781

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT7188980A PT71889B (de)	1980-10-08	1980-10-08	Verfahren zur gewinnung von silymarin aus pflanzen

Country Status (1)

Country	Link
PT (1)	PT71889B (pt)

1980
- 1980-10-08 PT PT7188980A patent/PT71889B/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT71889B (de)	1981-09-03

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Legal Events

Date

Code

Title

Description

1997-07-31

MM3A

Annulment or lapse

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 19970331