PT78865A - 8-De:methoxy steffimycinone antibacterial and intermediates - glycosidation, e.g. with amino-sugars, of the aglycone(s) produces anthracycline antitumour agents - Google Patents
8-De:methoxy steffimycinone antibacterial and intermediates - glycosidation, e.g. with amino-sugars, of the aglycone(s) produces anthracycline antitumour agentsInfo
- Publication number
- PT78865A PT78865A PT7886584A PT7886584A PT78865A PT 78865 A PT78865 A PT 78865A PT 7886584 A PT7886584 A PT 7886584A PT 7886584 A PT7886584 A PT 7886584A PT 78865 A PT78865 A PT 78865A
- Authority
- PT
- Portugal
- Prior art keywords
- steffimycinone
- amino
- glycosidation
- intermediates
- sugars
- Prior art date
Links
- 230000000259 anti-tumor effect Effects 0.000 title abstract 2
- 150000002337 glycosamines Chemical class 0.000 title abstract 2
- 238000005858 glycosidation reaction Methods 0.000 title abstract 2
- 239000000543 intermediate Substances 0.000 title abstract 2
- TWCMVXMQHSVIOJ-UHFFFAOYSA-N Aglycone of yadanzioside D Natural products COC(=O)C12OCC34C(CC5C(=CC(O)C(O)C5(C)C3C(O)C1O)C)OC(=O)C(OC(=O)C)C24 TWCMVXMQHSVIOJ-UHFFFAOYSA-N 0.000 title 1
- PLMKQQMDOMTZGG-UHFFFAOYSA-N Astrantiagenin E-methylester Natural products CC12CCC(O)C(C)(CO)C1CCC1(C)C2CC=C2C3CC(C)(C)CCC3(C(=O)OC)CCC21C PLMKQQMDOMTZGG-UHFFFAOYSA-N 0.000 title 1
- 229940045799 anthracyclines and related substance Drugs 0.000 title 1
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- PFOARMALXZGCHY-UHFFFAOYSA-N homoegonol Natural products C1=C(OC)C(OC)=CC=C1C1=CC2=CC(CCCO)=CC(OC)=C2O1 PFOARMALXZGCHY-UHFFFAOYSA-N 0.000 title 1
- -1 methoxy steffimycinone Chemical compound 0.000 title 1
- PDSIKDNPKQWQMS-UHFFFAOYSA-N 2,4,5,7-tetrahydroxy-3,4-dihydro-2H-tetracene-1,6,11-trione Chemical compound OC1C(C2=CC=3C(C4=CC=CC(=C4C(C=3C(=C2C(C1)O)O)=O)O)=O)=O PDSIKDNPKQWQMS-UHFFFAOYSA-N 0.000 abstract 1
- XCKPEEOERDVHKS-HLAWJBBLSA-N steffimycinone Chemical compound O=C1C2=C(O)C=C(OC)C=C2C(=O)C2=C1C(O)=C1[C@@H](O)[C@H](OC)[C@@](O)(C)C(=O)C1=C2 XCKPEEOERDVHKS-HLAWJBBLSA-N 0.000 abstract 1
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT7886584A PT78865B (fr) | 1984-07-06 | 1984-07-06 | Nouveau procede de preparation d'analogues de la steffimycinonenouveaux analogues de steffimycinone ainsi obtenus nouveaux intermediaires utiles pour la synthese de ces composes utilisation de ces composes en tant qu'antbacteriens et pour la synthese des antitumoraux |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT7886584A PT78865B (fr) | 1984-07-06 | 1984-07-06 | Nouveau procede de preparation d'analogues de la steffimycinonenouveaux analogues de steffimycinone ainsi obtenus nouveaux intermediaires utiles pour la synthese de ces composes utilisation de ces composes en tant qu'antbacteriens et pour la synthese des antitumoraux |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT78865A true PT78865A (en) | 1984-08-01 |
| PT78865B PT78865B (fr) | 1986-09-15 |
Family
ID=20083515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT7886584A PT78865B (fr) | 1984-07-06 | 1984-07-06 | Nouveau procede de preparation d'analogues de la steffimycinonenouveaux analogues de steffimycinone ainsi obtenus nouveaux intermediaires utiles pour la synthese de ces composes utilisation de ces composes en tant qu'antbacteriens et pour la synthese des antitumoraux |
Country Status (1)
| Country | Link |
|---|---|
| PT (1) | PT78865B (pt) |
-
1984
- 1984-07-06 PT PT7886584A patent/PT78865B/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT78865B (fr) | 1986-09-15 |
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