PT863797E - Particulas codificadas para permitirem seguir sequencias de processos na preparacao de bibliotecas de compostos combinatorios - Google Patents

Particulas codificadas para permitirem seguir sequencias de processos na preparacao de bibliotecas de compostos combinatorios

Info

Publication number
PT863797E
PT863797E PT96935090T PT96935090T PT863797E PT 863797 E PT863797 E PT 863797E PT 96935090 T PT96935090 T PT 96935090T PT 96935090 T PT96935090 T PT 96935090T PT 863797 E PT863797 E PT 863797E
Authority
PT
Portugal
Prior art keywords
libraries
preparation
allow
process sequences
combination compounds
Prior art date
Application number
PT96935090T
Other languages
English (en)
Portuguese (pt)
Inventor
Paul Henri Kaye
Mark Christopher Tracey
Original Assignee
Univ Hertfordshire
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10782942&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT863797(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Hertfordshire filed Critical Univ Hertfordshire
Publication of PT863797E publication Critical patent/PT863797E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/045—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/005—Beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00502—Particles of irregular geometry
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00547—Bar codes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00547—Bar codes
    • B01J2219/00549—2-dimensional
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554—Physical means
    • B01J2219/00556—Perforations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554—Physical means
    • B01J2219/00558—Cuts-out
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/0054—Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554—Physical means
    • B01J2219/0056—Raised or sunken areas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00592—Split-and-pool, mix-and-divide processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Pyrane Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Powder Metallurgy (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Auxiliary Devices For And Details Of Packaging Control (AREA)
  • Manufacture And Refinement Of Metals (AREA)
  • Control And Other Processes For Unpacking Of Materials (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
PT96935090T 1995-10-26 1996-10-25 Particulas codificadas para permitirem seguir sequencias de processos na preparacao de bibliotecas de compostos combinatorios PT863797E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9521943.2A GB9521943D0 (en) 1995-10-26 1995-10-26 Coded particles for process sequence tracking in combinatorial compound library preparation

Publications (1)

Publication Number Publication Date
PT863797E true PT863797E (pt) 2002-05-31

Family

ID=10782942

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96935090T PT863797E (pt) 1995-10-26 1996-10-25 Particulas codificadas para permitirem seguir sequencias de processos na preparacao de bibliotecas de compostos combinatorios

Country Status (11)

Country Link
EP (2) EP0863797B1 (2)
JP (1) JP2000516195A (2)
AT (1) ATE210496T1 (2)
AU (1) AU696505B2 (2)
CA (1) CA2235837A1 (2)
DE (1) DE69618001T2 (2)
DK (1) DK0863797T3 (2)
ES (1) ES2170276T3 (2)
GB (2) GB9521943D0 (2)
PT (1) PT863797E (2)
WO (1) WO1997015390A1 (2)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6284459B1 (en) 1995-04-25 2001-09-04 Discovery Partners International Solid support matrices with memories and combinatorial libraries therefrom
US6352854B1 (en) 1995-04-25 2002-03-05 Discovery Partners International, Inc. Remotely programmable matrices with memories
US6340588B1 (en) 1995-04-25 2002-01-22 Discovery Partners International, Inc. Matrices with memories
US6025129A (en) 1995-04-25 2000-02-15 Irori Remotely programmable matrices with memories and uses thereof
US6017496A (en) 1995-06-07 2000-01-25 Irori Matrices with memories and uses thereof
US6329139B1 (en) 1995-04-25 2001-12-11 Discovery Partners International Automated sorting system for matrices with memory
US6319668B1 (en) 1995-04-25 2001-11-20 Discovery Partners International Method for tagging and screening molecules
US6416714B1 (en) * 1995-04-25 2002-07-09 Discovery Partners International, Inc. Remotely programmable matrices with memories
US5741462A (en) 1995-04-25 1998-04-21 Irori Remotely programmable matrices with memories
US6100026A (en) * 1995-04-25 2000-08-08 Irori Matrices with memories and uses thereof
US6331273B1 (en) 1995-04-25 2001-12-18 Discovery Partners International Remotely programmable matrices with memories
US5874214A (en) 1995-04-25 1999-02-23 Irori Remotely programmable matrices with memories
CA2216645A1 (en) 1995-04-25 1996-11-21 Irori Remotely programmable matrices with memories and uses thereof
US5961923A (en) * 1995-04-25 1999-10-05 Irori Matrices with memories and uses thereof
GB2326152B (en) * 1996-03-07 2000-06-28 Imperial College A composite for combinatorial organic synthesis
GB2337269B (en) * 1997-04-17 2002-10-09 Zeneca Ltd Method for the preparation of a chemical library
GB9707742D0 (en) * 1997-04-17 1997-06-04 Zeneca Ltd Methods
GB9707741D0 (en) * 1997-04-17 1997-06-04 Zeneca Ltd Process
US6096496A (en) * 1997-06-19 2000-08-01 Frankel; Robert D. Supports incorporating vertical cavity emitting lasers and tracking apparatus for use in combinatorial synthesis
WO1999004895A1 (en) * 1997-07-24 1999-02-04 Argonaut Technologies, Inc. Compositions for the storage and delivery of solid phase reactive particles and methods of using the same
US6960457B1 (en) * 1997-09-04 2005-11-01 Stanford University Reversible immobilization of arginine-tagged moieties on a silicate surface
WO1999041006A1 (en) * 1998-02-13 1999-08-19 University Of Hertfordshire An improved method of fabricating coded particles
GB9814259D0 (en) * 1998-07-02 1998-09-02 Univ Hertfordshire Improvements to the fabrication and method of use of coded particles in the field of combinatorial chemistry
GB2334347B (en) * 1998-02-13 2001-02-28 Univ Hertfordshire An improved method of fabricating coded particles
EP1062034A1 (en) * 1998-03-13 2000-12-27 Central Research Laboratories Limited Apparatus for, and method of, manufacturing a plurality of uniquely labelled articles
GB9808783D0 (en) * 1998-04-25 1998-06-24 Central Research Lab Ltd Labelling of small articles
EP1090293B2 (en) 1998-06-24 2019-01-23 Illumina, Inc. Decoding of array sensors with microspheres
GB9820163D0 (en) * 1998-09-17 1998-11-11 Sentec Ltd Micro-fabricated coded labels, reading systems and their applications
CZ20013647A3 (cs) * 1999-04-09 2002-04-17 Glaxo Group Limited Chemická knihovna
US7253435B2 (en) 1999-04-15 2007-08-07 Millipore Corporation Particles with light-polarizing codes
KR20020026421A (ko) * 1999-04-15 2002-04-10 버츄얼 어레이즈 인코포레이티드 코딩 위치에 표시를 갖는 조합적인 화학 라이브러리지지체 및 이의 사용 방법
US6908737B2 (en) 1999-04-15 2005-06-21 Vitra Bioscience, Inc. Systems and methods of conducting multiplexed experiments
WO2000063695A1 (en) 1999-04-16 2000-10-26 Tibotec N.V. Encoding of microcarriers
US6919009B2 (en) 1999-10-01 2005-07-19 Nanoplex Technologies, Inc. Method of manufacture of colloidal rod particles as nanobarcodes
US7045049B1 (en) 1999-10-01 2006-05-16 Nanoplex Technologies, Inc. Method of manufacture of colloidal rod particles as nanobar codes
US7225082B1 (en) 1999-10-01 2007-05-29 Oxonica, Inc. Colloidal rod particles as nanobar codes
JP2004501344A (ja) * 2000-04-19 2004-01-15 スリー・ディ・モレキュラー・サイエンシィズ・リミテッド コード化された粒子を製造する方法
JP2004537712A (ja) 2000-10-18 2004-12-16 バーチャル・アレイズ・インコーポレーテッド 多重細胞分析システム
US7015047B2 (en) 2001-01-26 2006-03-21 Aviva Biosciences Corporation Microdevices having a preferential axis of magnetization and uses thereof
US7811768B2 (en) 2001-01-26 2010-10-12 Aviva Biosciences Corporation Microdevice containing photorecognizable coding patterns and methods of using and producing the same
GB0109545D0 (en) * 2001-04-18 2001-06-06 Scient Generics Ltd Chemical libraries based on coded particles
GB0109746D0 (en) * 2001-04-18 2001-06-13 Scient Generics Ltd Chemical libraries based on coded particles
US7572642B2 (en) 2001-04-18 2009-08-11 Ambrigen, Llc Assay based on particles, which specifically bind with targets in spatially distributed characteristic patterns
GB0111470D0 (en) * 2001-05-10 2001-07-04 Scient Generics Ltd Homogenous photoresist functionalisation
WO2003038558A2 (en) * 2001-10-30 2003-05-08 Nanomics Biosystems Pty, Ltd. Device and methods for directed synthesis of chemical libraries
EP1581792A4 (en) * 2002-06-21 2008-07-23 Stephen D Nightingale MULTIFUNCTIONAL PRODUCT MARKERS AND METHODS OF MANUFACTURING AND USING THE SAME
US7923260B2 (en) 2002-08-20 2011-04-12 Illumina, Inc. Method of reading encoded particles
US7900836B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Optical reader system for substrates having an optically readable code
US7619819B2 (en) 2002-08-20 2009-11-17 Illumina, Inc. Method and apparatus for drug product tracking using encoded optical identification elements
US7399643B2 (en) 2002-09-12 2008-07-15 Cyvera Corporation Method and apparatus for aligning microbeads in order to interrogate the same
US7164533B2 (en) 2003-01-22 2007-01-16 Cyvera Corporation Hybrid random bead/chip based microarray
US7508608B2 (en) 2004-11-17 2009-03-24 Illumina, Inc. Lithographically fabricated holographic optical identification element
US7901630B2 (en) 2002-08-20 2011-03-08 Illumina, Inc. Diffraction grating-based encoded microparticle assay stick
US7441703B2 (en) 2002-08-20 2008-10-28 Illumina, Inc. Optical reader for diffraction grating-based encoded optical identification elements
US7872804B2 (en) 2002-08-20 2011-01-18 Illumina, Inc. Encoded particle having a grating with variations in the refractive index
US20040058457A1 (en) * 2002-08-29 2004-03-25 Xueying Huang Functionalized nanoparticles
US20100255603A9 (en) 2002-09-12 2010-10-07 Putnam Martin A Method and apparatus for aligning microbeads in order to interrogate the same
US7092160B2 (en) 2002-09-12 2006-08-15 Illumina, Inc. Method of manufacturing of diffraction grating-based optical identification element
EP1540591A1 (en) 2002-09-12 2005-06-15 Cyvera Corporation Diffraction grating-based encoded micro-particles for multiplexed experiments
WO2004038037A2 (en) * 2002-09-20 2004-05-06 Intel Corporation Controlled alignment of nano-barcodes encoding specific information for scanning probe microscopy (spm) reading
US7361821B2 (en) 2002-09-20 2008-04-22 Intel Corporation Controlled alignment of nanobarcodes encoding specific information for scanning probe microscopy (SPM) reading
US8791053B2 (en) 2002-09-27 2014-07-29 Mpm-Holding Aps Spatially encoded polymer matrix
GB2393785B (en) 2002-10-03 2005-08-31 Toshiba Res Europ Ltd Method of making a free standing structure
GB2393784B (en) * 2002-10-03 2005-06-15 Toshiba Res Europ Ltd An identification tag and method of making an identification tag
US7312257B2 (en) 2003-01-23 2007-12-25 General Electric Company Polymer encapsulation of high aspect ratio materials and methods of making same
GB2405013B (en) * 2003-08-11 2006-02-15 Toshiba Res Europ Ltd A security marker and security marking method
US7488451B2 (en) 2003-09-15 2009-02-10 Millipore Corporation Systems for particle manipulation
WO2005061094A1 (en) 2003-12-22 2005-07-07 Versamatrix A/S Identification of encoded beads
EP1699553A2 (en) 2003-12-22 2006-09-13 VersaMatrix A/S Apparatus and methods for analysis and sorting of particles such as polymer beads
US7433123B2 (en) 2004-02-19 2008-10-07 Illumina, Inc. Optical identification element having non-waveguide photosensitive substrate with diffraction grating therein
US20050277710A1 (en) * 2004-06-14 2005-12-15 Joyce Richard P Tagged resin, method of making a tagged resin, and articles made therefrom
US7604173B2 (en) 2004-11-16 2009-10-20 Illumina, Inc. Holographically encoded elements for microarray and other tagging labeling applications, and method and apparatus for making and reading the same
WO2006055735A2 (en) 2004-11-16 2006-05-26 Illumina, Inc Scanner having spatial light modulator
EP2194485B1 (en) 2004-11-16 2012-10-17 Illumina, Inc. Method and apparatus for reading coded microbeads
GB2422686A (en) * 2004-12-07 2006-08-02 Univ Southampton Preparation of solid support particles for chemical reactions
WO2006061600A1 (en) * 2004-12-07 2006-06-15 University Of Southampton Particles for use as a solid support and process for their preparation
US8178278B2 (en) 2005-09-13 2012-05-15 Affymetrix, Inc. Miniaturized microparticles
US20100227770A1 (en) 2005-09-13 2010-09-09 Randall True Brownian microbarcodes for bioassays
US7623624B2 (en) 2005-11-22 2009-11-24 Illumina, Inc. Method and apparatus for labeling using optical identification elements characterized by X-ray diffraction
EP2384811A1 (en) 2006-01-11 2011-11-09 Novo Nordisk A/S A spherical encoded bead with an ultrasonic identification chip
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
JP4803125B2 (ja) * 2007-05-10 2011-10-26 ソニー株式会社 ビーズ群と該ビーズ群の作製方法、並びにビーズ群を用いる方法
EP1995329B1 (en) 2007-05-10 2013-09-25 Sony Corporation Method for sequencing nucleic acids
JP4973993B2 (ja) * 2007-07-23 2012-07-11 財団法人生産技術研究奨励会 マイクロビーズの配列装置における解放装置及びその解放装置の設定方法
GB0725306D0 (en) * 2007-12-28 2008-02-06 Pronostics Ltd Improved microparticles
JP2009174954A (ja) * 2008-01-23 2009-08-06 Fujitsu Ltd コード化粒子
JP4582224B2 (ja) 2008-05-02 2010-11-17 ソニー株式会社 マイクロビーズ作製方法及びマイクロビーズ
US9182406B2 (en) 2008-08-04 2015-11-10 Biodesy, Inc. Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability
EP2312393A1 (en) 2009-10-14 2011-04-20 Biocartis SA Method for producing microparticles
GB2503604B (en) 2011-03-21 2020-04-22 Biodesy Llc Classification of kinase inhibitors using second harmonic optical techniques
US9139863B2 (en) 2012-03-16 2015-09-22 Genentech, Inc. Engineered conformationally-stabilized proteins
RU2014141617A (ru) 2012-03-16 2016-05-10 Дженентек, Инк. Сконструированные конформационно-стабилизированные белки
GB2517857A (en) 2012-04-25 2015-03-04 Biodesy Inc Methods for detecting allosteric modulators of proteins
US10436778B2 (en) 2013-03-15 2019-10-08 Plexbio Co., Ltd. Methods and systems for multiplex assays
EP3636073B1 (en) 2014-05-05 2023-11-15 Regeneron Pharmaceuticals, Inc. Humanized c5 and c3 animals
WO2016106286A1 (en) 2014-12-23 2016-06-30 Biodesy, Inc. Attachment of proteins to interfaces for use in nonlinear optical detection
TWI737614B (zh) 2015-06-11 2021-09-01 博錸生技股份有限公司 已編碼微載體及其製造方法以及用以進行多工分析之包含該等已編碼微載體之套件
US11135221B2 (en) 2015-12-23 2021-10-05 Moonshot Pharma Llc Methods for inducing an immune response
EP3513186A4 (en) 2016-09-16 2020-04-29 Plexbio Co., Ltd. METHODS AND SYSTEMS FOR MULTIPLEX TESTS
SG10202111663PA (en) 2017-02-27 2021-12-30 Regeneron Pharma Humanized model of kidney and liver disorders
JP2020525434A (ja) 2017-06-22 2020-08-27 ムーンショット ファーマ エルエルシー アンレキサノクス及び免疫調節剤を含む組成物で癌を治療する方法
EP4293568B1 (en) * 2019-01-23 2025-08-27 BGI Shenzhen Microbead

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053433A (en) * 1975-02-19 1977-10-11 Minnesota Mining And Manufacturing Company Method of tagging with color-coded microparticles
CA1056653A (en) * 1975-11-10 1979-06-19 Edward J. Stevens Color-coded identifier microparticles
US4390452A (en) * 1979-08-20 1983-06-28 Minnesota Mining & Manufacturing Company Microparticles with visual identifying means
US4631211A (en) * 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
US4767205A (en) * 1986-01-28 1988-08-30 Flow Cytometry Standards Corporation Composition and method for hidden identification
US5770358A (en) * 1991-09-18 1998-06-23 Affymax Technologies N.V. Tagged synthetic oligomer libraries
AU680450B2 (en) * 1992-11-06 1997-07-31 Mimotopes Pty Ltd Support for the synthesis of modular polymers
US5429392A (en) * 1993-06-18 1995-07-04 Loving; Charles D. Composite microdot and method
GB2289150B (en) * 1994-04-25 1998-07-15 Univ Hertfordshire Coded items for labelling objects

Also Published As

Publication number Publication date
ATE210496T1 (de) 2001-12-15
DE69618001D1 (de) 2002-01-24
ES2170276T3 (es) 2002-08-01
EP1018365A3 (en) 2000-10-11
CA2235837A1 (en) 1997-05-01
GB9521943D0 (en) 1996-01-03
AU696505B2 (en) 1998-09-10
GB9622249D0 (en) 1996-12-18
DK0863797T3 (da) 2002-04-15
DE69618001T2 (de) 2002-08-14
GB2306484A (en) 1997-05-07
EP0863797B1 (en) 2001-12-12
EP0863797A1 (en) 1998-09-16
EP1018365A2 (en) 2000-07-12
EP1018365A9 (en) 2001-05-16
JP2000516195A (ja) 2000-12-05
WO1997015390A1 (en) 1997-05-01
EP1018365A8 (en) 2001-03-28
GB2306484B (en) 1997-09-24
AU7318496A (en) 1997-05-15

Similar Documents

Publication Publication Date Title
PT863797E (pt) Particulas codificadas para permitirem seguir sequencias de processos na preparacao de bibliotecas de compostos combinatorios
FI964520L (fi) Atsabisykloyhdisteet
MA21509A1 (fr) Composition de colorant photoactivateur a usage detergent .
FR2720356B1 (fr) Procédé pour déterminer la sensibilité de déclenchement d'une opération de freinage automatique.
FI895389A0 (fi) Foerfarande foer framstaellning av 3,5 -dimetyl-4-metoxipyridinderivat samt ny mellanprodukt haerfoer.
GR920300076T1 (en) 1,2-dioxetane compounds as chemiluminescent labels for organic and biological molecules
TW222289B (2)
OA09457A (fr) Procédé pour la valorisation des boues d'épuration.
EP0406028A3 (en) Incremental compiler for source code development system
AR245207A1 (es) Composiciones detergentes liquidas con capacidad para suspender material en particulas.
GB2229732B (en) Detergent granules
NO308700B1 (no) En fremgangsmÕte ved fremstilling av et intermediat nyttig i syntesen av ioderte kontrastmidler, samt fremgangsmÕte ved fremstilling av Iopamidol
EG19008A (en) A method for the preparation of novel iodinated nonionic triodobenzene compounds and of contrast media containing them
BR9003672A (pt) Processo para fabricacao descontinua de l-carnitina por via microbiologica
IT1245845B (it) Processo per la depurazione di un monomero vinilaromatico.
ES2084692T3 (es) Proceso para la aminacion de fenoles.
ITRM920231V0 (it) Guarnizione senza amianto, in particolare per freni
IT1265456B1 (it) Processo per la purificazione di composti organici
FR2654839B1 (fr) Appareil pour l'etude de la stratosphere par sondage laser.
GB9000300D0 (en) New compounds for biochemical use
GB9026949D0 (en) New compounds for biochemical use
GB9000240D0 (en) New compounds for biochemical use
GB9026950D0 (en) New compounds for biochemical use
GB9026951D0 (en) New compounds for biochemical use
BR9807188A (pt) Processo para separação de 2-amino-metil-ciclo-pentil-amina de uma mistura compreendendo hexametileno-diamina e 2-amino-etil-ciclo-pentil-amina.