SE7416083L - - Google Patents
Info
- Publication number
- SE7416083L SE7416083L SE7416083A SE7416083A SE7416083L SE 7416083 L SE7416083 L SE 7416083L SE 7416083 A SE7416083 A SE 7416083A SE 7416083 A SE7416083 A SE 7416083A SE 7416083 L SE7416083 L SE 7416083L
- Authority
- SE
- Sweden
- Prior art keywords
- hydrogen
- lower alkyl
- bromine
- chlorine
- fluorine
- Prior art date
Links
- 239000001257 hydrogen Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 229910052794 bromium Inorganic materials 0.000 abstract 2
- 229910052801 chlorine Inorganic materials 0.000 abstract 2
- 239000000460 chlorine Chemical group 0.000 abstract 2
- 229910052731 fluorine Chemical group 0.000 abstract 2
- 239000011737 fluorine Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- -1 -O?-R2 Substances 0.000 abstract 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 229910052740 iodine Inorganic materials 0.000 abstract 1
- 239000011630 iodine Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
This invention describes novel 4,5-seco-steroids having the formula wherein A is -C=CH, -CH=CH2, -CH2CH3, or -?CH3; X1 is hydrogen, chlorine, bromine, or fluorine; R1 is hydrogen, hydroxyl, -O?-R2, chlorine, bromine, fluorine or iodine; R2 is lower alkyl; P is hydrogen, lower alkyl, or aryl; Q is lower alkyl or aryl; Y is hydrogen and Y' is hydroxyl or together Y and Y' are =O and a process for preparing these compounds which are useful as anti-inflammatory agents.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42716873A | 1973-12-20 | 1973-12-20 | |
| US52217974A | 1974-11-08 | 1974-11-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE7416083L true SE7416083L (en) | 1975-06-23 |
Family
ID=27027315
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7416083A SE7416083L (en) | 1973-12-20 | 1974-12-19 |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS5095268A (en) |
| CA (1) | CA1047507A (en) |
| DD (1) | DD116032A5 (en) |
| DE (1) | DE2459467A1 (en) |
| DK (1) | DK666074A (en) |
| FR (1) | FR2255061A1 (en) |
| GB (1) | GB1483944A (en) |
| HU (1) | HU171180B (en) |
| NL (1) | NL7416492A (en) |
| NO (1) | NO744612L (en) |
| SE (1) | SE7416083L (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3984474A (en) * | 1975-05-30 | 1976-10-05 | E. R. Squibb & Sons, Inc. | 4,5-Secoandrostanes |
-
1974
- 1974-12-11 CA CA215,719A patent/CA1047507A/en not_active Expired
- 1974-12-16 DE DE19742459467 patent/DE2459467A1/en active Pending
- 1974-12-18 GB GB54692/74A patent/GB1483944A/en not_active Expired
- 1974-12-18 NL NL7416492A patent/NL7416492A/en unknown
- 1974-12-18 DD DD183163A patent/DD116032A5/xx unknown
- 1974-12-18 HU HU74SU00000883A patent/HU171180B/en unknown
- 1974-12-19 NO NO744612A patent/NO744612L/no unknown
- 1974-12-19 SE SE7416083A patent/SE7416083L/xx not_active Application Discontinuation
- 1974-12-19 DK DK666074A patent/DK666074A/da unknown
- 1974-12-20 JP JP49147489A patent/JPS5095268A/ja active Pending
- 1974-12-20 FR FR7442340A patent/FR2255061A1/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| HU171180B (en) | 1977-11-28 |
| CA1047507A (en) | 1979-01-30 |
| GB1483944A (en) | 1977-08-24 |
| DD116032A5 (en) | 1975-11-05 |
| DK666074A (en) | 1975-08-25 |
| DE2459467A1 (en) | 1975-07-10 |
| NL7416492A (en) | 1975-06-24 |
| FR2255061A1 (en) | 1975-07-18 |
| NO744612L (en) | 1975-07-14 |
| JPS5095268A (en) | 1975-07-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
Ref document number: 7416083-9 |