SE7903231L - PHARMACEUTICAL COMPOSITION CONTAINING ANTRANILIC ACID DERIVATIVES AS AN ANTI-DIABETIC - Google Patents
PHARMACEUTICAL COMPOSITION CONTAINING ANTRANILIC ACID DERIVATIVES AS AN ANTI-DIABETICInfo
- Publication number
- SE7903231L SE7903231L SE7903231A SE7903231A SE7903231L SE 7903231 L SE7903231 L SE 7903231L SE 7903231 A SE7903231 A SE 7903231A SE 7903231 A SE7903231 A SE 7903231A SE 7903231 L SE7903231 L SE 7903231L
- Authority
- SE
- Sweden
- Prior art keywords
- acid derivatives
- diabetic
- pharmaceutical composition
- composition containing
- hydrogen
- Prior art date
Links
- RWZYAGGXGHYGMB-UHFFFAOYSA-N anthranilic acid Chemical class NC1=CC=CC=C1C(O)=O RWZYAGGXGHYGMB-UHFFFAOYSA-N 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 230000003178 anti-diabetic effect Effects 0.000 title 1
- 239000003472 antidiabetic agent Substances 0.000 title 1
- 239000001257 hydrogen Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 4
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- CVICEEPAFUYBJG-UHFFFAOYSA-N 5-chloro-2,2-difluoro-1,3-benzodioxole Chemical group C1=C(Cl)C=C2OC(F)(F)OC2=C1 CVICEEPAFUYBJG-UHFFFAOYSA-N 0.000 abstract 1
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical compound FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Pharmaceutical compositions containing anthranilic acid derivatives of formula I, <IMAGE> in which R0 is fluorine, chlorine, bromine, nitro or trifluoromethyl, R is hydrogen, C1-6alkyl or C2-4 alkanoyl, and R1 is hydrogen or C1-6alkyl, provided that a) when each of R and R1 is hydrogen, R0 is other than 5-chloro; and b) when R is acetyl and R1 is hydrogen, R0 is other than 5- or 6-chloro, 5-bromo or 5-trifluoromethyl, are indicated for use in treating diabetes.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89816078A | 1978-04-20 | 1978-04-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE7903231L true SE7903231L (en) | 1979-10-21 |
Family
ID=25409043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7903231A SE7903231L (en) | 1978-04-20 | 1979-04-11 | PHARMACEUTICAL COMPOSITION CONTAINING ANTRANILIC ACID DERIVATIVES AS AN ANTI-DIABETIC |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS54141747A (en) |
| AU (1) | AU4610479A (en) |
| BE (1) | BE875669A (en) |
| DE (1) | DE2914935A1 (en) |
| FR (1) | FR2430230A1 (en) |
| GB (1) | GB2019214A (en) |
| IL (1) | IL57090A0 (en) |
| IT (1) | IT7948749A0 (en) |
| NL (1) | NL7902908A (en) |
| NZ (1) | NZ190206A (en) |
| SE (1) | SE7903231L (en) |
| ZA (1) | ZA791894B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN152997B (en) * | 1979-08-17 | 1984-05-19 | Council Scient Ind Res | |
| CA1181420A (en) * | 1980-12-29 | 1985-01-22 | Michael J. Fifolt | Method for the preparation of fluoroanthranilic compounds |
| US5514676A (en) * | 1984-03-19 | 1996-05-07 | The Rockefeller University | Amino-benzoic acids and derivatives, and methods of use |
| US5476849A (en) * | 1984-03-19 | 1995-12-19 | The Rockefeller University | Methods for glycosylation inhibition using amino-benzoic acids and derivatives |
| DE3682136D1 (en) * | 1985-07-31 | 1991-11-28 | Hoechst Ag | N-SUBSTITUTED 5-NITROANTHRANILE ACIDS, METHOD FOR THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS. |
| AU8449591A (en) * | 1990-08-01 | 1992-03-02 | Rockefeller University, The | Advanced glycation inhibitors containing amino-benzoic acids and derivatives, and methods of use |
| US5741926A (en) * | 1997-02-12 | 1998-04-21 | Shaman Pharmaceuticals, Inc. | Aniline derivatives having antihyperglycemic activity |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR7409M (en) * | 1968-06-28 | 1969-11-03 | ||
| DE2311020A1 (en) * | 1973-03-06 | 1974-09-12 | Pfizer | SUBSTITUTED BENZOIC ACIDS AND MEDICINAL PRODUCTS |
| US4060638A (en) * | 1975-05-27 | 1977-11-29 | Sandoz, Inc. | Anthranilic acid amides |
-
1979
- 1979-04-11 SE SE7903231A patent/SE7903231L/en not_active Application Discontinuation
- 1979-04-12 NL NL7902908A patent/NL7902908A/en not_active Application Discontinuation
- 1979-04-12 DE DE19792914935 patent/DE2914935A1/en not_active Withdrawn
- 1979-04-17 IT IT7948749A patent/IT7948749A0/en unknown
- 1979-04-18 BE BE0/194684A patent/BE875669A/en unknown
- 1979-04-18 NZ NZ190206A patent/NZ190206A/en unknown
- 1979-04-18 JP JP4680079A patent/JPS54141747A/en active Pending
- 1979-04-18 GB GB7913457A patent/GB2019214A/en not_active Withdrawn
- 1979-04-18 AU AU46104/79A patent/AU4610479A/en not_active Abandoned
- 1979-04-19 IL IL57090A patent/IL57090A0/en unknown
- 1979-04-20 FR FR7909988A patent/FR2430230A1/en not_active Withdrawn
- 1979-04-20 ZA ZA791894A patent/ZA791894B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL57090A0 (en) | 1979-07-25 |
| BE875669A (en) | 1979-10-18 |
| AU4610479A (en) | 1979-10-25 |
| NL7902908A (en) | 1979-10-23 |
| ZA791894B (en) | 1980-11-26 |
| FR2430230A1 (en) | 1980-02-01 |
| GB2019214A (en) | 1979-10-31 |
| DE2914935A1 (en) | 1979-10-31 |
| NZ190206A (en) | 1981-07-13 |
| JPS54141747A (en) | 1979-11-05 |
| IT7948749A0 (en) | 1979-04-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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