SE8006860L - Cefalosporinantibiotika - Google Patents

Cefalosporinantibiotika

Info

Publication number
SE8006860L
SE8006860L SE8006860A SE8006860A SE8006860L SE 8006860 L SE8006860 L SE 8006860L SE 8006860 A SE8006860 A SE 8006860A SE 8006860 A SE8006860 A SE 8006860A SE 8006860 L SE8006860 L SE 8006860L
Authority
SE
Sweden
Prior art keywords
bishydrochloride
cephalosporin antibiotics
crystalline
pyridiniummethyl
carboxyprop
Prior art date
Application number
SE8006860A
Other languages
English (en)
Swedish (sv)
Other versions
SE449996B (sv
Inventor
T Miller
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of SE8006860L publication Critical patent/SE8006860L/
Publication of SE449996B publication Critical patent/SE449996B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE8006860A 1979-10-02 1980-10-01 (6r,7r)-7-/(z)-2-(2-aminotiazol-4-yl)-2-(2-karboxiprop-2-oxiimino)acetamidol/-3-(1-pyridiniummetyl)cef-3-em-4-karboxylat i form av en kristallin bishydroklorid farmaceutisk komposition derav samt anvendning som mellanpr SE449996B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7934203 1979-10-02

Publications (2)

Publication Number Publication Date
SE8006860L true SE8006860L (sv) 1981-04-03
SE449996B SE449996B (sv) 1987-06-01

Family

ID=10508245

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8006860A SE449996B (sv) 1979-10-02 1980-10-01 (6r,7r)-7-/(z)-2-(2-aminotiazol-4-yl)-2-(2-karboxiprop-2-oxiimino)acetamidol/-3-(1-pyridiniummetyl)cef-3-em-4-karboxylat i form av en kristallin bishydroklorid farmaceutisk komposition derav samt anvendning som mellanpr

Country Status (14)

Country Link
US (1) US4467086A ( )
JP (1) JPS5657789A ( )
AU (1) AU540382B2 ( )
BE (1) BE885488A ( )
CH (1) CH644609A5 ( )
DE (1) DE3037104C2 ( )
FR (1) FR2466469A1 ( )
GB (1) GB2064513B ( )
IE (1) IE50269B1 ( )
IT (1) IT1128569B ( )
NL (1) NL8005439A ( )
NZ (1) NZ195116A ( )
SE (1) SE449996B ( )
ZA (1) ZA806082B ( )

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4963542A (en) * 1976-09-08 1990-10-16 Takeda Chemical Industries, Ltd. Cephalosporin derivatives
CH654010A5 (de) * 1979-05-25 1986-01-31 Glaxo Group Ltd Zwischenprodukte zur verwendung bei der herstellung von cephalosporin-antibiotika.
US4594417A (en) * 1981-10-30 1986-06-10 Eli Lilly Company Crystalline antibiotic salt
US4400503A (en) 1981-10-30 1983-08-23 Eli Lilly And Company Purification of syn-7-[[(2-amino-4-thiazolyl)(methoxyimino) acetyl]amino]-3-methyl-3-cephem-4-carboxylic acid
US4394503A (en) 1981-12-07 1983-07-19 Bristol-Myers Company Cephalosporin derivatives
US4474954A (en) * 1981-12-07 1984-10-02 Bristol-Myers Company Intermediates for cephalosporin derivatives
DE3248281A1 (de) * 1982-12-28 1984-06-28 Hoechst Ag, 6230 Frankfurt Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3313816A1 (de) * 1983-04-16 1984-10-18 Hoechst Ag, 6230 Frankfurt Neue kristallmodifikation von ceftazidim
DE3313818A1 (de) * 1983-04-16 1984-10-18 Hoechst Ag, 6230 Frankfurt Neue kristallmodifikation von ceftazidim
US4537959A (en) * 1984-03-26 1985-08-27 Eli Lilly And Company Crystalline cephalosporin antibiotic salt
US4616080A (en) * 1984-07-02 1986-10-07 Eli Lilly And Company Simplified process of forming crystalline ceftazidime pentahydrate
US5244891A (en) * 1985-08-05 1993-09-14 Bristol-Myers Squibb Company Injectable compositions of cefepime dihydrochloride hydrate
AT387022B (de) * 1986-06-04 1988-11-25 Biochemie Gmbh Verfahren zur herstellung einer neuen kristallinen form eines cefalosporinderivats
DE3706020A1 (de) * 1987-02-25 1988-09-08 Hoechst Ag Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
GB8802622D0 (en) * 1988-02-05 1988-03-02 Glaxo Group Ltd Chemical compound
JPH02101081A (ja) * 1988-10-08 1990-04-12 Meiji Seika Kaisha Ltd セファロスポリン誘導体結晶性二塩酸塩及びその製造法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR228726A1 (es) * 1978-05-26 1983-04-15 Glaxo Group Ltd Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
CH654010A5 (de) * 1979-05-25 1986-01-31 Glaxo Group Ltd Zwischenprodukte zur verwendung bei der herstellung von cephalosporin-antibiotika.

Also Published As

Publication number Publication date
AU540382B2 (en) 1984-11-15
JPS5657789A (en) 1981-05-20
CH644609A5 (de) 1984-08-15
AU6288080A (en) 1981-04-09
IT1128569B (it) 1986-05-28
GB2064513B (en) 1983-09-14
IE802051L (en) 1981-04-02
DE3037104C2 (de) 1986-04-30
JPH0245634B2 ( ) 1990-10-11
ZA806082B (en) 1982-05-26
SE449996B (sv) 1987-06-01
US4467086A (en) 1984-08-21
BE885488A (fr) 1981-04-01
FR2466469B1 ( ) 1984-02-10
GB2064513A (en) 1981-06-17
IE50269B1 (en) 1986-03-19
NL8005439A (nl) 1981-04-06
IT8049782A0 (it) 1980-10-01
NZ195116A (en) 1982-09-07
FR2466469A1 (fr) 1981-04-10
DE3037104A1 (de) 1981-04-16

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