SG10202000486VA - Systems and methods to detect rare mutations and copy number variation - Google Patents

Systems and methods to detect rare mutations and copy number variation

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Publication number
SG10202000486VA
SG10202000486VA SG10202000486VA SG10202000486VA SG10202000486VA SG 10202000486V A SG10202000486V A SG 10202000486VA SG 10202000486V A SG10202000486V A SG 10202000486VA SG 10202000486V A SG10202000486V A SG 10202000486VA SG 10202000486V A SG10202000486V A SG 10202000486VA
Authority
SG
Singapore
Prior art keywords
systems
methods
copy number
number variation
rare mutations
Prior art date
Application number
SG10202000486VA
Other languages
English (en)
Inventor
Amirali Talasaz
Helmy Eltoukhy
Original Assignee
Guardant Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50237580&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10202000486V(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Guardant Health Inc filed Critical Guardant Health Inc
Publication of SG10202000486VA publication Critical patent/SG10202000486VA/en

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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
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    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
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    • G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
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    • G16B30/10—Sequence alignment; Homology search
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    • C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
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    • C12Q2545/00—Reactions characterised by their quantitative nature
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    • C12Q2600/00—Oligonucleotides characterized by their use
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
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SG10202000486VA 2012-09-04 2013-09-04 Systems and methods to detect rare mutations and copy number variation SG10202000486VA (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261696734P 2012-09-04 2012-09-04
US201261704400P 2012-09-21 2012-09-21
US201361793997P 2013-03-15 2013-03-15
US201361845987P 2013-07-13 2013-07-13

Publications (1)

Publication Number Publication Date
SG10202000486VA true SG10202000486VA (en) 2020-03-30

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ID=50237580

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Application Number Title Priority Date Filing Date
SG10202000486VA SG10202000486VA (en) 2012-09-04 2013-09-04 Systems and methods to detect rare mutations and copy number variation
SG11201501662TA SG11201501662TA (en) 2012-09-04 2013-09-04 Systems and methods to detect rare mutations and copy number variation

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SG11201501662TA SG11201501662TA (en) 2012-09-04 2013-09-04 Systems and methods to detect rare mutations and copy number variation

Country Status (17)

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US (31) US10041127B2 (es)
EP (6) EP2893040B1 (es)
JP (6) JP6275145B2 (es)
KR (6) KR102393608B1 (es)
CN (2) CN104781421B (es)
CA (2) CA3190199A1 (es)
DE (1) DE202013012824U1 (es)
DK (1) DK2893040T5 (es)
ES (5) ES2769241T5 (es)
GB (1) GB2533006B (es)
HK (1) HK1225416B (es)
IL (3) IL305303A (es)
MX (1) MX367963B (es)
PL (2) PL3591073T3 (es)
PT (1) PT2893040T (es)
SG (2) SG10202000486VA (es)
WO (1) WO2014039556A1 (es)

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