SI9300595B - Peptidi z organo-protektivno aktivnostjo, postopki za njihovo pripravo in njihova uporaba v terapiji - Google Patents

Peptidi z organo-protektivno aktivnostjo, postopki za njihovo pripravo in njihova uporaba v terapiji Download PDF

Info

Publication number: SI9300595B
Authority: SI; Slovenia
Prior art keywords: xaa; disorders; amino acid; peptides; zaa
Prior art date: 1992-11-16

Application number

SI9300595A

Other languages

English (en)

Slovenian (sl)

Other versions

SI9300595A (en

Inventor

Predrag Sikiri

Marijan Petek

Sven Seiwerth

�eljko Grabarevi�

Ivo Rotkovi�

Marko Duvnjak

Branko Turkovi

Stjepan Mi�e

Ernest Sushanek

Boris Mildner

Ivan Udivi�i�

Original Assignee

Predrag Sikiri

Marijan Petek

Sven Seiwerth

�eljko Grabarevi�

Rotkvi Ivo

Marko Duvnjak

Branko Turkovi

Stjepan Mi�e

Suchanek Ernest

Boris Mildner

Udovi�i� Ivan

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-11-16

Filing date

1993-11-16

Publication date

2003-04-30

1993-11-16 Application filed by Predrag Sikiri, Marijan Petek, Sven Seiwerth, �eljko Grabarevi�, Rotkvi Ivo, Marko Duvnjak, Branko Turkovi, Stjepan Mi�e, Suchanek Ernest, Boris Mildner, Udovi�i� Ivan filed Critical Predrag Sikiri

1994-09-30 Publication of SI9300595A publication Critical patent/SI9300595A/sl

2003-04-30 Publication of SI9300595B publication Critical patent/SI9300595B/sl

Links

108090000765 processed proteins & peptides Proteins 0.000 title claims abstract 6
102000004196 processed proteins & peptides Human genes 0.000 title claims abstract 5
230000000694 effects Effects 0.000 title abstract 2
230000001225 therapeutic effect Effects 0.000 title 1
125000000539 amino acid group Chemical group 0.000 claims abstract 5
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
208000035475 disorder Diseases 0.000 claims 2
206010003694 Atrophy Diseases 0.000 claims 1
206010053567 Coagulopathies Diseases 0.000 claims 1
206010020772 Hypertension Diseases 0.000 claims 1
208000017657 Menopausal disease Diseases 0.000 claims 1
APKRGYLBSCWJJP-FXQIFTODSA-N Pro-Ala-Asp Chemical compound [H]N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(O)=O APKRGYLBSCWJJP-FXQIFTODSA-N 0.000 claims 1
SBVPYBFMIGDIDX-SRVKXCTJSA-N Pro-Pro-Pro Chemical compound OC(=O)[C@@H]1CCCN1C(=O)[C@H]1N(C(=O)[C@H]2NCCC2)CCC1 SBVPYBFMIGDIDX-SRVKXCTJSA-N 0.000 claims 1
244000191761 Sida cordifolia Species 0.000 claims 1
231100000644 Toxic injury Toxicity 0.000 claims 1
210000001015 abdomen Anatomy 0.000 claims 1
239000002253 acid Substances 0.000 claims 1
230000002378 acidificating effect Effects 0.000 claims 1
-1 aliphatic amino acids Chemical class 0.000 claims 1
230000037444 atrophy Effects 0.000 claims 1
UCMIRNVEIXFBKS-UHFFFAOYSA-N beta-alanine Chemical compound NCCC(O)=O UCMIRNVEIXFBKS-UHFFFAOYSA-N 0.000 claims 1
208000015294 blood coagulation disease Diseases 0.000 claims 1
230000036760 body temperature Effects 0.000 claims 1
230000009852 coagulant defect Effects 0.000 claims 1
230000006378 damage Effects 0.000 claims 1
206010012601 diabetes mellitus Diseases 0.000 claims 1
230000003394 haemopoietic effect Effects 0.000 claims 1
208000031169 hemorrhagic disease Diseases 0.000 claims 1
230000000302 ischemic effect Effects 0.000 claims 1
210000003734 kidney Anatomy 0.000 claims 1
210000004185 liver Anatomy 0.000 claims 1
239000000203 mixture Substances 0.000 claims 1
230000007935 neutral effect Effects 0.000 claims 1
210000000496 pancreas Anatomy 0.000 claims 1
239000008194 pharmaceutical composition Substances 0.000 claims 1
208000020016 psychiatric disease Diseases 0.000 claims 1
210000001550 testis Anatomy 0.000 claims 1
230000004071 biological effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000007086 side reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Cardiology (AREA)
Gastroenterology & Hepatology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Zoology (AREA)
Emergency Medicine (AREA)
Obesity (AREA)
Biophysics (AREA)
Reproductive Health (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Urology & Nephrology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

SI9300595A 1992-11-16 1993-11-16 Peptidi z organo-protektivno aktivnostjo, postopki za njihovo pripravo in njihova uporaba v terapiji SI9300595B (sl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HR921283		1992-11-16

Publications (2)

Publication Number	Publication Date
SI9300595A SI9300595A (en)	1994-09-30
SI9300595B true SI9300595B (sl)	2003-04-30

Family

ID=10945833

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI9300595A SI9300595B (sl)	1992-11-16	1993-11-16	Peptidi z organo-protektivno aktivnostjo, postopki za njihovo pripravo in njihova uporaba v terapiji

Country Status (17)

Country	Link
EP (1)	EP0624164B1 (cs)
JP (1)	JP2812803B2 (cs)
AT (1)	ATE163131T1 (cs)
AU (1)	AU5624994A (cs)
BG (1)	BG61697B1 (cs)
CA (1)	CA2127553C (cs)
CZ (1)	CZ285155B6 (cs)
DE (1)	DE69316974T2 (cs)
ES (1)	ES2114170T3 (cs)
GR (1)	GR3026478T3 (cs)
HU (3)	HUT67982A (cs)
PL (1)	PL304666A1 (cs)
RO (1)	RO115733B1 (cs)
RU (1)	RU2116311C1 (cs)
SI (1)	SI9300595B (cs)
SK (1)	SK279227B6 (cs)
WO (1)	WO1994011394A2 (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69826653T2 (de) *	1997-05-23	2006-03-09	Sikirić, Predrag, Dr.sc.	Bpc peptid salze mit organ-schützender aktivität, deren herstellung und therapeutische verwendung
SI24318A (sl) *	2013-03-13	2014-09-30	Diagen D.O.O.	Nove stabilne soli pentadekapeptida, postopek za njihovo pripravo, njihova uporaba za izdelavo farmacevtskih pripravkov in njihova uporaba v terapiji

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
YU176089A (sh) *	1989-09-12	1992-09-07	Sikirić, Predrag	Postupak za pripremu supstancije bpc i supstancija bpc
CA2107674A1 (en)	1991-04-08	1992-10-09	W. Lee Maloy	Novel peptide compositions and uses therefor
ATE152734T1 (de) *	1992-05-30	1997-05-15	Sikiric Predrag	Bpc-peptide, deren herstellung und verwendung

1993
- 1993-11-16 EP EP94901809A patent/EP0624164B1/en not_active Expired - Lifetime
- 1993-11-16 HU HU9401952A patent/HUT67982A/hu unknown
- 1993-11-16 CA CA002127553A patent/CA2127553C/en not_active Expired - Fee Related
- 1993-11-16 RU RU94037232A patent/RU2116311C1/ru not_active IP Right Cessation
- 1993-11-16 SI SI9300595A patent/SI9300595B/sl not_active IP Right Cessation
- 1993-11-16 AT AT94901809T patent/ATE163131T1/de active
- 1993-11-16 ES ES94901809T patent/ES2114170T3/es not_active Expired - Lifetime
- 1993-11-16 JP JP6511727A patent/JP2812803B2/ja not_active Expired - Fee Related
- 1993-11-16 SK SK857-94A patent/SK279227B6/sk not_active IP Right Cessation
- 1993-11-16 AU AU56249/94A patent/AU5624994A/en not_active Abandoned
- 1993-11-16 CZ CZ941622A patent/CZ285155B6/cs not_active IP Right Cessation
- 1993-11-16 HU HU9303247A patent/HUT66303A/hu unknown
- 1993-11-16 RO RO94-01091A patent/RO115733B1/ro unknown
- 1993-11-16 PL PL93304666A patent/PL304666A1/xx unknown
- 1993-11-16 WO PCT/EP1993/003217 patent/WO1994011394A2/en not_active Ceased
- 1993-11-16 DE DE69316974T patent/DE69316974T2/de not_active Expired - Lifetime
1994
- 1994-07-15 BG BG98907A patent/BG61697B1/bg unknown
1995
- 1995-06-21 HU HU95P/P00304P patent/HU211260A9/hu unknown
1998
- 1998-03-27 GR GR980400664T patent/GR3026478T3/el unknown

Also Published As

Publication number	Publication date
AU5624994A (en)	1994-06-08
CZ285155B6 (cs)	1999-05-12
HU9401952D0 (en)	1994-09-28
RU2116311C1 (ru)	1998-07-27
WO1994011394A2 (en)	1994-05-26
SI9300595A (en)	1994-09-30
GR3026478T3 (en)	1998-06-30
BG98907A (bg)	1995-05-31
HU9303247D0 (en)	1994-03-28
CZ162294A3 (en)	1995-02-15
JP2812803B2 (ja)	1998-10-22
BG61697B1 (bg)	1998-03-31
EP0624164B1 (en)	1998-02-11
ATE163131T1 (de)	1998-02-15
HU211260A9 (en)	1995-11-28
SK85794A3 (en)	1995-01-12
RO115733B1 (ro)	2000-05-30
HUT67982A (en)	1995-05-29
WO1994011394A3 (en)	1994-09-15
CA2127553A1 (en)	1994-05-26
EP0624164A1 (en)	1994-11-17
ES2114170T3 (es)	1998-05-16
SK279227B6 (sk)	1998-08-05
HUT66303A (en)	1994-11-28
CA2127553C (en)	2003-01-28
RU94037232A (ru)	1996-06-20
PL304666A1 (en)	1995-01-09
DE69316974T2 (de)	1998-07-16
DE69316974D1 (de)	1998-03-19
JPH07507568A (ja)	1995-08-24

Legal Events

Date	Code	Title	Description
2005-01-10	IF	Valid on the event date
2012-07-31	KO00	Lapse of patent	Effective date: 20120627

Publication	Publication Date	Title
JPH0532696A (ja)	1993-02-09	副甲状腺ホルモン誘導体
ES2001274A6 (es)	1988-05-01	Un metodo para preparar peptidos que tienen influencia sobre la funcion de la glandula pituitaria en seres humanos y otros animales
IL69897A (en)	1986-12-31	Human pancreatic grf analogs,compositions comprising them and use thereof
CA2027936A1 (en)	1991-04-24	Cyclic anti-aggregatory peptides
AR006517A1 (es)	1999-09-08	Polipeptido que alcanza un total de alrededor de 30 aminoacidos; sustancia, peptidomimetico y composicion farmaceutica resultantes; usos del polipeptidoy proceso para la sintesis del polipeptido.
KR930701483A (ko)	1993-06-11	Grf (쥐이알에프) 유사체 xi
DK355889A (da)	1990-01-23	Syntetisk peptid og farmaceutisk middel indeholdende peptidet
CA2453112A1 (en)	2003-02-06	New cationic peptides of the dermaseptin family isolated from the skin secretion of phyllomedusa hypochondrialls
US5786335A (en)	1998-07-28	Sulfhydryl containing peptides for treating vascular disease
AU641215B2 (en)	1993-09-16	Stabilized sulfonate, sulfate, phosphonate and phosphate derivatives of hirudin
JPH03120297A (ja)	1991-05-22	抗凝固ペプチド
US6743895B1 (en)	2004-06-01	Bone stimulating factor
KR0162893B1 (ko)	1998-11-16	항응고성 펩타이드 및 이를 함유하는 조성물
SI9300595B (sl)	2003-04-30	Peptidi z organo-protektivno aktivnostjo, postopki za njihovo pripravo in njihova uporaba v terapiji
CA2063260A1 (en)	1990-12-30	Vasodilatory and immune suppressant peptides
Kiyama et al.	1987	Synthesis of porcine neuropeptide Y (NPY) in solution
HU187503B (en)	1986-01-28	Process for preparing gonadoliberine derivatives containing beta-aspartyl group
JP2003501109A5 (cs)	2007-07-05
LEE et al.	1984	Serratia protease. Amino acid sequences of both termini, the 53 residues in the middle region containing the sole methionine residue, and a probable zinc-binding region
WO2000075185A1 (en)	2000-12-14	Bone stimulating factor
JPH05500962A (ja)	1993-02-25	硫酸エステル基を有するヘキサペプチド