SMT201700159T1 - Identificazione di forme extracellulari di pten che possono essere usate per trattare tumori - Google Patents

Identificazione di forme extracellulari di pten che possono essere usate per trattare tumori

Info

Publication number
SMT201700159T1
SMT201700159T1 SM20170159T SMT201700159T SMT201700159T1 SM T201700159 T1 SMT201700159 T1 SM T201700159T1 SM 20170159 T SM20170159 T SM 20170159T SM T201700159 T SMT201700159 T SM T201700159T SM T201700159 T1 SMT201700159 T1 SM T201700159T1
Authority
SM
San Marino
Prior art keywords
pten
identification
treat tumors
extracellular form
extracellular
Prior art date
Application number
SM20170159T
Other languages
English (en)
Inventor
Ramon Parsons
Original Assignee
Univ Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Columbia filed Critical Univ Columbia
Publication of SMT201700159T1 publication Critical patent/SMT201700159T1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SM20170159T 2009-02-17 2010-02-17 Identificazione di forme extracellulari di pten che possono essere usate per trattare tumori SMT201700159T1 (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US20797409P 2009-02-17 2009-02-17
EP10744058.8A EP2400973B1 (en) 2009-02-17 2010-02-17 Identification of extracellular form of pten that can be used to treat tumors
PCT/US2010/000469 WO2010096173A2 (en) 2009-02-17 2010-02-17 Identification of extracellular form of pten that can be used to treat tumors

Publications (1)

Publication Number Publication Date
SMT201700159T1 true SMT201700159T1 (it) 2017-05-08

Family

ID=42634379

Family Applications (1)

Application Number Title Priority Date Filing Date
SM20170159T SMT201700159T1 (it) 2009-02-17 2010-02-17 Identificazione di forme extracellulari di pten che possono essere usate per trattare tumori

Country Status (19)

Country Link
US (1) US9017981B2 (it)
EP (1) EP2400973B1 (it)
JP (2) JP5767117B2 (it)
CN (1) CN102387810B (it)
AU (2) AU2010216370A1 (it)
BR (1) BRPI1005951A2 (it)
CA (1) CA2752590C (it)
CY (1) CY1118861T1 (it)
DK (1) DK2400973T3 (it)
ES (1) ES2623393T3 (it)
HR (1) HRP20170306T1 (it)
HU (1) HUE032028T2 (it)
LT (1) LT2400973T (it)
MX (1) MX2011008695A (it)
PL (1) PL2400973T3 (it)
PT (1) PT2400973T (it)
SI (1) SI2400973T1 (it)
SM (1) SMT201700159T1 (it)
WO (1) WO2010096173A2 (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102844043B (zh) * 2010-02-17 2015-07-29 纽约哥伦比亚大学理事会 使用PTEN-Long前导序列进行分子的跨膜递送
WO2015105957A1 (en) 2014-01-08 2015-07-16 Shriners Hospitals For Children Pten antagonist peptides and methods of using the same
SG11201900815UA (en) * 2016-07-29 2019-02-27 Ohio State Innovation Foundation Expression of pten-long with ocolytic viruses
CN109022461B (zh) * 2017-06-08 2022-01-14 中山大学附属第一医院 一种PTEN基因的上游开放阅读框45aa-uORF核苷酸序列及其编码的多肽的应用
CN108504671A (zh) * 2018-03-28 2018-09-07 宁波市医疗中心李惠利医院 一种PTEN-Long蛋白纯化制备方法
US11648260B2 (en) 2018-03-29 2023-05-16 Technion Research And Development Foundation Limitted Vesicles comprising a PTEN inhibitor and uses of same
CA3134665A1 (en) 2019-04-12 2020-10-15 Therapten Biosciences Inc. Compositions and methods to manufacture tumor suppressor fusions
BR112022001912A2 (pt) * 2019-08-05 2022-04-19 Mesoblast Int Sarl Composições celulares compreendendo vetores virais e métodos de tratamento
CN112813046A (zh) * 2021-01-08 2021-05-18 北京大学 一种pten亚型蛋白及其应用
CN112877309B (zh) * 2021-02-19 2022-05-17 北京大学 一种N端延长型PTEN亚型PTENζ蛋白及其编码基因和应用
WO2024163335A2 (en) * 2023-01-30 2024-08-08 The Board Of Regents Of The University Of Texas System Pten gene therapy vectors and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6482795B1 (en) 1997-01-30 2002-11-19 Myriad Genetics, Inc. Tumor suppressor designated TS10q23.3
US6777439B2 (en) * 2000-05-30 2004-08-17 Advanced Research & Technology Institute, Inc. Compositions and methods for identifying agents which modulate PTEN function and PI-3 kinase pathways
US20040266713A1 (en) 2003-04-23 2004-12-30 Shan Lu Methods and compositions for solid tumor treatment
WO2006034455A2 (en) 2004-09-23 2006-03-30 Vasgene Therapeutics, Inc. Polipeptide compounds for inhibiting angiogenesis and tumor growth
CN102844043B (zh) 2010-02-17 2015-07-29 纽约哥伦比亚大学理事会 使用PTEN-Long前导序列进行分子的跨膜递送

Also Published As

Publication number Publication date
PT2400973T (pt) 2017-03-07
US9017981B2 (en) 2015-04-28
WO2010096173A3 (en) 2010-10-21
MX2011008695A (es) 2011-10-14
WO2010096173A2 (en) 2010-08-26
AU2016231517B2 (en) 2018-01-25
ES2623393T3 (es) 2017-07-11
AU2016231517A1 (en) 2016-10-06
JP2012517827A (ja) 2012-08-09
CA2752590A1 (en) 2010-08-26
JP5767117B2 (ja) 2015-08-19
PL2400973T3 (pl) 2017-09-29
JP2015231372A (ja) 2015-12-24
CA2752590C (en) 2017-08-22
EP2400973B1 (en) 2016-11-30
BRPI1005951A2 (pt) 2016-10-11
CN102387810A (zh) 2012-03-21
CY1118861T1 (el) 2018-01-10
US20120039861A1 (en) 2012-02-16
SI2400973T1 (sl) 2017-05-31
DK2400973T3 (en) 2017-03-06
EP2400973A4 (en) 2013-02-27
LT2400973T (lt) 2017-04-10
AU2010216370A1 (en) 2011-09-22
CN102387810B (zh) 2017-08-04
EP2400973A2 (en) 2012-01-04
JP5973035B2 (ja) 2016-08-17
HRP20170306T1 (hr) 2017-04-21
HUE032028T2 (en) 2017-08-28

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