TH62744B - Flavone derivatives New types of C-glycosides And derivative elements - Google Patents

Abstract

DC60 (19/06/52) This invention relates to a new type of C-glycoside flavone derivative or salt of These derivatives Especially The more those derivatives, which show anti-allergic effects. And elements with These derivatives Not long ago Cases of allergies Especially hay fever and autoimmune dermatitis Allergies have risen to the stage at which these diseases are becoming a social problem. Flavones and glycosides of flavones have been reported as Has the effect of inhibiting the release of histamine from Cell Mast or Effect Decreased immunity And is expected for its use as an allergy treatment. However, almost all flavones All of these are shown only at high dosing effects. Therefore, compounds that are effective at dosing at So low is highly desirable The invention provides a new type of ingredient capable of treating allergies at scale. Use the low and the available elements. These components This invention is related to flavone derivatives. A new type of C-glycoside or salt of These derivatives Especially The more recent those derivatives that showed anti-allergic effects and the mixtures containing these derivatives Cases of allergies Especially hay fever and autoimmune dermatitis Allergies have risen to the stage at which these diseases are becoming a social problem. Flavones and glycosides of flavones have been reported as Has the effect of inhibiting the release of histamine from Cell Mast or Effect Decreased immunity And is expected for its implementation. As an allergy treatment, however, almost all flavones All of these are shown only at high dosing results. So low is highly desirable The invention provides a new type of ingredient capable of treating allergies at scale. Use low and low mixtures available. These components

Claims (9)

1.Flavone derivatives C-glycosides with formula (1) (chemical formula) or salts of these derivatives. 2.Flavone derivatives C-glycosides with formula (2) (chemical formula) or salts of these derivatives. 3. Pharmaceutical Mixture for Prevention And / or treatment Allergies, which contain flavones, C-glycosides, or salts Of at least one of these derivatives pursuant to either Clause 1 or Clause 2. 4. Pharmaceutical mixtures according to claim 3, where autoimmune diseases Such allergies were selected from Atopic dermatitis Contact dermatitis Or at least one type of hay fever 5. Dietary mixtures containing flavone derivatives, C-glycosides, or salts of these derivatives. At least one of its kind according to Any claim No. 1 or No. 2 As is the anti-allergic component 6. Food Mixture according to claim 5 in form of substance Nutritional supplements or beverages containing other nutrients Health drink Health tea Or any other kind of drink 7. Nutritional mixtures according to claim 5 in the form of desserts, breads, noodle products, processed soy products, dairy products, processed egg products, meats, seasoned fish, fats and oils. Or any kind of flavoring 8. Cosmetics with flavone derivatives. C-glycosides or Salt of these derivatives. At least one of the types of claims 1 or 2. As is the anti-allergic component 9. Cosmetics according to Clause 8 in the form of skin care products, makeup products Hair cosmetics or any type of bath products 1 0.Using flavone derivatives C-glycosides or salt of These derivatives, at least One of the types according to claim 1 or item 2, any For the preparation of pharmaceutical mixtures, food mixtures Or cosmetics with anti-allergic effects