WO1986007357A2 - Cyclopentapyrazole and tetrahydroindazole compounds - Google Patents

Cyclopentapyrazole and tetrahydroindazole compounds Download PDF

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Publication number
WO1986007357A2
WO1986007357A2 PCT/US1986/001233 US8601233W WO8607357A2 WO 1986007357 A2 WO1986007357 A2 WO 1986007357A2 US 8601233 W US8601233 W US 8601233W WO 8607357 A2 WO8607357 A2 WO 8607357A2
Authority
WO
WIPO (PCT)
Prior art keywords
cyclopentapyrazole
tetrahydroindazole
compounds
novel
agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1986/001233
Other languages
French (fr)
Other versions
WO1986007357A3 (en
Inventor
Herman W Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of WO1986007357A2 publication Critical patent/WO1986007357A2/en
Publication of WO1986007357A3 publication Critical patent/WO1986007357A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel compositions of matter and their therapeutic applications. More particularly, the present invention consists of novel cyclopentapyrazole and tetrahydroindazole compounds of formula (XXX) and their use as antiallergy agents, antiinflammatory agents or intermediates.
PCT/US1986/001233 1985-06-14 1986-06-03 Cyclopentapyrazole and tetrahydroindazole compounds Ceased WO1986007357A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74534385A 1985-06-14 1985-06-14
US745,343 1985-06-14

Publications (2)

Publication Number Publication Date
WO1986007357A2 true WO1986007357A2 (en) 1986-12-18
WO1986007357A3 WO1986007357A3 (en) 1987-04-23

Family

ID=24996305

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1986/001233 Ceased WO1986007357A2 (en) 1985-06-14 1986-06-03 Cyclopentapyrazole and tetrahydroindazole compounds

Country Status (3)

Country Link
US (1) US4851425A (en)
EP (1) EP0226624A1 (en)
WO (1) WO1986007357A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0529854A3 (en) * 1991-08-08 1993-03-31 Ortho Pharmaceutical Corporation Tetrahydroindazole, tetrahydrocyclopentapyrazole, and hexahydrocycloheptapyrazole compounds and their use as hmg-coa reductase inhibitors
US5817669A (en) * 1994-06-14 1998-10-06 Dainippon Pharmaceutical Co., Ltd. Compounds, processes for the preparation thereof and anti-tumor agents

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA010887B1 (en) * 2004-03-24 2008-12-30 Янссен Фармацевтика Н.В. Tetrahydro-indazole cannabinoid modulators
RU2459808C1 (en) * 2011-02-25 2012-08-27 Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет" 3-(1-naphthylmethyl)-4,5,6,7-tetrahydroindazole hydrochloride exhibiting antimicrobial properties

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1948793A1 (en) * 1969-09-26 1971-04-01 Rhein Chemie Rheinau Gmbh Process for the preparation of 4,5,6,7-tetrahydroindazoles
JPS50157363A (en) * 1974-06-06 1975-12-19
FR2315924A1 (en) * 1975-07-03 1977-01-28 Enzypha Analgesic and antiinflammatory polymethylene pyrazole derivs. - prepd. by cyclizing 2-acyl cyclic ketones with hydrazine derivs.
SU553246A1 (en) * 1975-10-07 1977-04-05 Московский Ордена Ленина И Ордена Трудового Красного Знамени Химикотехнологический Институт Им.Д.И.Менделеева The method of obtaining indazol-3-aldehyde

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0529854A3 (en) * 1991-08-08 1993-03-31 Ortho Pharmaceutical Corporation Tetrahydroindazole, tetrahydrocyclopentapyrazole, and hexahydrocycloheptapyrazole compounds and their use as hmg-coa reductase inhibitors
AU656602B2 (en) * 1991-08-08 1995-02-09 Ortho Pharmaceutical Corporation HMG-COA reductase inhibitors
US5817669A (en) * 1994-06-14 1998-10-06 Dainippon Pharmaceutical Co., Ltd. Compounds, processes for the preparation thereof and anti-tumor agents

Also Published As

Publication number Publication date
US4851425A (en) 1989-07-25
EP0226624A1 (en) 1987-07-01
WO1986007357A3 (en) 1987-04-23

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