WO1993025143A1 - A method relating to collecting blood samples in conjunction with blood taking processus - Google Patents

A method relating to collecting blood samples in conjunction with blood taking processus Download PDF

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Publication number
WO1993025143A1
WO1993025143A1 PCT/SE1993/000463 SE9300463W WO9325143A1 WO 1993025143 A1 WO1993025143 A1 WO 1993025143A1 SE 9300463 W SE9300463 W SE 9300463W WO 9325143 A1 WO9325143 A1 WO 9325143A1
Authority
WO
WIPO (PCT)
Prior art keywords
hose
blood
coupling
needle
sub
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/SE1993/000463
Other languages
French (fr)
Inventor
Ulla Meirik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to SK270-94A priority Critical patent/SK27094A3/en
Priority to JP6501370A priority patent/JPH06509735A/en
Priority to CZ94502A priority patent/CZ50294A3/en
Priority to FI940523A priority patent/FI940523A7/en
Priority to AU43645/93A priority patent/AU4364593A/en
Priority to CA002114324A priority patent/CA2114324A1/en
Priority to EP93913709A priority patent/EP0606425A1/en
Priority to PL93302314A priority patent/PL302314A1/en
Application filed by Individual filed Critical Individual
Publication of WO1993025143A1 publication Critical patent/WO1993025143A1/en
Priority to NO940332A priority patent/NO940332D0/en
Priority to BG98485A priority patent/BG98485A/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
    • A61B5/154—Devices using pre-evacuated means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/15003—Source of blood for venous or arterial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150992—Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; Blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings or valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/84—Drainage tubes; Aspiration tips
    • A61M1/86—Connectors between drainage tube and handpiece, e.g. drainage tubes detachable from handpiece
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150503—Single-ended needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150534—Design of protective means for piercing elements for preventing accidental needle sticks, e.g. shields, caps, protectors, axially extensible sleeves, pivotable protective sleeves
    • A61B5/150572—Pierceable protectors, e.g. shields, caps, sleeves or films, e.g. for hygienic purposes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3496—Plasmapheresis; Leucopheresis; Lymphopheresis

Definitions

  • the present invention relates to a method according to the preamble of Claim 1.
  • a hose extends from the needle inserted into the blood donor to a blood bag and possible accessories.
  • the bag is typically placed on scales which detect when the correct amount of blood has been taken from the donor, whereupon the hose is automatically clamped tightly in the vicinity of the blood bag, thereby throttling the blood flow.
  • a metal clip is then attached to the hose and the hose is severed between the metal clip and a pair of hemostatic forceps, whereafter the blood bag is taken away for further treatment.
  • the blood is emptied from the bag into open test tubes, by opening the for ⁇ ceps attached to that part of the hose which is connect ⁇ ed to the needle.
  • test tubes Subsequent to having filled one or more test tubes with a given amount of blood, this amount being judged solely by looking at the test tubes, the open test tubes are carried to a bench. Loose stop ⁇ pers are now inserted into respective tubes, which are then shaken on a rotating disc, in a conventional man- ner.
  • the object of the present invention is to fully elimi ⁇ nate the drawbacks of the aforedescribed, earlier known method of procedure, and therewith also to eliminate the risk of infection to the personnel handling the blood taking equipment.
  • Figure 1 is a schematic illustration of a blood taking process and shows the initial stage of a blood sampling process
  • Figures 2 and 3 illustrate schematically a first stage of a blood sampling process
  • Figure 4 illus ⁇ trates the second stage of a blood sampling process
  • Figure 5 illustrates the third stage of a blood sampling process in larger scale.
  • Shown in the drawing is a blood bag 1 and a hose 2 extending from said bag.
  • the needle to be inserted into the blood donor is referenced 3 and is connected to a hose part 4 which is connected to the hose 2 by means of a hose coupling 5 (in the illustrated case a known Luer cap fitting) .
  • the hose part 4 is also provided with a hose clamp 6.
  • Figure 1 illustrates the situation in which the needle 3 is attached to the donor, the hose clamp 6 is open and blood is drained into the bag 1.
  • the hose 2 When the bag has received the correct amount of blood, as indicated by means of the scales mentioned in the introduction, the hose 2 is squeezed together with the aid of some type of clamp which cannot be opened, for instance a metal clip, or the hose may be heat-fused together (as indicated schematically at 7 in Figures 2 and 3).
  • the clamp 6 is activated to seal-off the hose part 4, whereafter the hose 2 is released from the hose part 4 through the agency of the hose coupling 5.
  • the blood bag 1 and hose 2 are removed for further processing.
  • the coupling 5 (Luer cap fitting) of the hose part 4 is then connected to a known sleeve for sub-pressure tube 9 - see Figure 4.
  • a needle-like adapter 10 Inserted in the sleeve in a known manner is a needle-like adapter 10 (see Figure 5) which is surrounded by a stocking 11 which can be penetrated by the needle.
  • the sleeve 9 has a hose coupling (Luer cap fitting) which fits onto the hose coupling 5.
  • a test tube under sub-pressure and fitted with a rubber stopper is inserted in the sleeve, so that the needle 10, which is displaced by the stocking 11, penetrates the stopper 13.
  • the hose clamp 6 is opened and the tube 12 is filled with an exact amount of blood, as a result of the sub-pressure prevailing in the tube.
  • the sub-pressure tube 12 is then removed and the hole made by the needle 10 in the stopper closes automati ⁇ cally as the rubber in the stopper 13 reasserts itself.
  • the tube 12 can now be transported away for further processing of the blood, without risk of blood spilling therefrom.
  • the problem can also conceivably be solved by attaching a so-called Y-coupling to an additional hose for blood sampling purposes.
  • the additional hose must be provided with a fracture pin or a hose clamp and also a Luer cap stopper at one end. This method would enable samples of blood to be taken during the actual blood letting process.
  • the cou ⁇ pling (the Luer cap fitting) may be provided in practice with some form of seal when fitted for delivery, for instance a shrink plastic covering, so that the receiver is able to ascertain whether or not the coupling is intact and therewith sterile.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • External Artificial Organs (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A method pertaining to sampling blood in conjunction with blood taking processes and manual plasmapheresis with the aid of a blood bag (1) and connecting hose (2, 4) and a needle (3) which is intended for insertion into the blood donor, in a known manner. The method is characterized in that the hose is provided with a hose coupling (5) and in that a hose clamp (6) is fitted between the coupling and the needle. When sampling blood, the hose (2, 4) is closed-off on both sides of the coupling (5) and the coupling is then loosened and that part of the coupling which is connected to the needle-accommodating part of the hose (4) is connected to a sub-pressure sleeve or the like, in which one or more sub-pressure tubes or the like in sequence is/are inserted for collecting blood samples.

Description

A method relating to collecting blood samples in con¬ junction with blood taking processes
The present invention relates to a method according to the preamble of Claim 1.
Present day methods of collecting blood samples in conjunction with a blood taking process, and in con¬ junction with manual plasmapheresis, are unacceptable from the aspect of infection and contagion.
A hose extends from the needle inserted into the blood donor to a blood bag and possible accessories. The bag is typically placed on scales which detect when the correct amount of blood has been taken from the donor, whereupon the hose is automatically clamped tightly in the vicinity of the blood bag, thereby throttling the blood flow. A metal clip is then attached to the hose and the hose is severed between the metal clip and a pair of hemostatic forceps, whereafter the blood bag is taken away for further treatment. The blood is emptied from the bag into open test tubes, by opening the for¬ ceps attached to that part of the hose which is connect¬ ed to the needle. Subsequent to having filled one or more test tubes with a given amount of blood, this amount being judged solely by looking at the test tubes, the open test tubes are carried to a bench. Loose stop¬ pers are now inserted into respective tubes, which are then shaken on a rotating disc, in a conventional man- ner.
This hitherto applied method of procedure has many drawbacks. For instance, the hose is clipped-off with the aid of scissors (the same pair of scissors through- out the working day) , which incurs the risk of blood spillage and dirty scissors. Furthermore, the blood is emptied into open tubes, which incurs the risk of fur¬ ther blood spillage and of blood being deposited on the outer surfaces of contaminated tubes. The blood can easily splash-up from the tubes as the results of invol- untary knocks during transportation of the tubes and as the tubes are placed onto a bench. The application of loose stoppers or corks means that the stoppers may loosen from the tubes as they sit on the rotating disc. On the other hand, if the stoppers are pressed too hard in the tubes, there is a risk of the tubes breaking and resulting in further blood spillage and possible cuts to the person handling the tubes. The personnel handling the blood taking equipment are thus exposed to very serious risks of contagion and infection, with the serious consequences that this implies.
The object of the present invention is to fully elimi¬ nate the drawbacks of the aforedescribed, earlier known method of procedure, and therewith also to eliminate the risk of infection to the personnel handling the blood taking equipment. These objects are achieved in accor¬ dance with the invention with the method defined in the characterizing clauses of the following claims.
The invention will now be described in more detail with reference to the accompanying drawing, which illustrates schematically a method of procedure when taking blood from a blood donor.
Figure 1 is a schematic illustration of a blood taking process and shows the initial stage of a blood sampling process; Figures 2 and 3 illustrate schematically a first stage of a blood sampling process; Figure 4 illus¬ trates the second stage of a blood sampling process; and Figure 5 illustrates the third stage of a blood sampling process in larger scale. Shown in the drawing is a blood bag 1 and a hose 2 extending from said bag. The needle to be inserted into the blood donor is referenced 3 and is connected to a hose part 4 which is connected to the hose 2 by means of a hose coupling 5 (in the illustrated case a known Luer cap fitting) . The hose part 4 is also provided with a hose clamp 6.
Figure 1 illustrates the situation in which the needle 3 is attached to the donor, the hose clamp 6 is open and blood is drained into the bag 1.
When the bag has received the correct amount of blood, as indicated by means of the scales mentioned in the introduction, the hose 2 is squeezed together with the aid of some type of clamp which cannot be opened, for instance a metal clip, or the hose may be heat-fused together (as indicated schematically at 7 in Figures 2 and 3). The clamp 6 is activated to seal-off the hose part 4, whereafter the hose 2 is released from the hose part 4 through the agency of the hose coupling 5.
The blood bag 1 and hose 2 are removed for further processing.
The coupling 5 (Luer cap fitting) of the hose part 4 is then connected to a known sleeve for sub-pressure tube 9 - see Figure 4. Inserted in the sleeve in a known manner is a needle-like adapter 10 (see Figure 5) which is surrounded by a stocking 11 which can be penetrated by the needle. It shall be understood that the sleeve 9 has a hose coupling (Luer cap fitting) which fits onto the hose coupling 5.
A test tube under sub-pressure and fitted with a rubber stopper is inserted in the sleeve, so that the needle 10, which is displaced by the stocking 11, penetrates the stopper 13. The hose clamp 6 is opened and the tube 12 is filled with an exact amount of blood, as a result of the sub-pressure prevailing in the tube.
The sub-pressure tube 12 is then removed and the hole made by the needle 10 in the stopper closes automati¬ cally as the rubber in the stopper 13 reasserts itself.
The tube 12 can now be transported away for further processing of the blood, without risk of blood spilling therefrom.
It will be evident from the aforedescribed method steps that no blood will be spilled or contaminate the person taking or sampling the blood, while each tube can be filled with an exact quantity of blood.
The problem can also conceivably be solved by attaching a so-called Y-coupling to an additional hose for blood sampling purposes. In this case, the additional hose must be provided with a fracture pin or a hose clamp and also a Luer cap stopper at one end. This method would enable samples of blood to be taken during the actual blood letting process.
Subsequent to running tests on the basis of this con¬ cept, the idea was shelved because the blood remained stationary in the hose and the Y-piece activates coagu- lation factors which can be carried down into the col¬ lecting vessel, which most certainly must not happen.
This risk is totally eliminated with the concept first described, since the blood collecting vessel is discon- nected during the actual blood taking process. This solution is also extremely easy to apply, cheap in manufacture, readily sterilized and readily packaged.
In order to enhance the safety of the system, the cou¬ pling (the Luer cap fitting) may be provided in practice with some form of seal when fitted for delivery, for instance a shrink plastic covering, so that the receiver is able to ascertain whether or not the coupling is intact and therewith sterile.

Claims

1. A method pertaining to taking blood samples in con¬ junction with blood taking processes and manual plasma- pheresis with the aid of a blood bag (1) and a connect¬ ing hose (2, 4) provided with a needle (3) which is intended for insertion into the blood donor, in a known manner, c h a r a c t e r i z e d by fitting the hose with a hose coupling (5); fitting a hose clamp (6) between said coupling and said needle, such that the hose is closed- off on both sides of the coupling (5) when sampling blood; releasing the coupling; connecting that part of the coupling which is connected to the part of the hose (4) provided with said needle to a sub-pressure sleeve
(9) or the like in which a sub-pressure tube (12) or the like or a sequence of sub-pressure tubes (12) or the like is/are introduced for collecting a blood sample.
2. A method according to Claim 1, c h a r a c ¬ t e r i z e d by using a coupling in the form of a Luer cap fitting (5) .
3. A method according to Claim 1 or 2, c h a r a c - t e r i z e d by closing-off that part of the hose (2) which is connected to the bag (1) by heat-fusing said hose or with the aid of a hose clip.
PCT/SE1993/000463 1992-06-05 1993-05-26 A method relating to collecting blood samples in conjunction with blood taking processus Ceased WO1993025143A1 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
PL93302314A PL302314A1 (en) 1992-06-05 1993-05-26 Method of taking away blood samples during the sampling process
JP6501370A JPH06509735A (en) 1992-06-05 1993-05-26 Methods for collecting blood samples related to blood sampling methods
CZ94502A CZ50294A3 (en) 1992-06-05 1993-05-26 Method relating to collecting blood samples combined with procedures of blood sampling
FI940523A FI940523A7 (en) 1992-06-05 1993-05-26 A method associated with the collection of blood samples in connection with blood sampling procedures
AU43645/93A AU4364593A (en) 1992-06-05 1993-05-26 A method relating to collecting blood samples in conjunction with blood taking processus
SK270-94A SK27094A3 (en) 1992-06-05 1993-05-26 Method relating to collecting of blood samples in combination with the bleeding process
EP93913709A EP0606425A1 (en) 1992-06-05 1993-05-26 A method relating to collecting blood samples in conjunction with blood taking processus
CA002114324A CA2114324A1 (en) 1992-06-05 1993-05-26 A method relating to collecting blood samples in conjunction with blood taking processes
NO940332A NO940332D0 (en) 1992-06-05 1994-02-01 Procedure for collecting blood samples
BG98485A BG98485A (en) 1992-06-05 1994-02-18 METHOD CONCERNING BLOOD SAMPLING RELATED TO BLOOD SAMPLING PROCESSES

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9201738A SE502351C2 (en) 1992-06-05 1992-06-05 Procedure and apparatus for blood sampling
SE9201738-3 1992-06-05

Publications (1)

Publication Number Publication Date
WO1993025143A1 true WO1993025143A1 (en) 1993-12-23

Family

ID=20386422

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SE1993/000463 Ceased WO1993025143A1 (en) 1992-06-05 1993-05-26 A method relating to collecting blood samples in conjunction with blood taking processus

Country Status (12)

Country Link
EP (1) EP0606425A1 (en)
JP (1) JPH06509735A (en)
AU (1) AU4364593A (en)
BG (1) BG98485A (en)
CA (1) CA2114324A1 (en)
CZ (1) CZ50294A3 (en)
FI (1) FI940523A7 (en)
PL (1) PL302314A1 (en)
RU (1) RU94016157A (en)
SE (1) SE502351C2 (en)
SK (1) SK27094A3 (en)
WO (1) WO1993025143A1 (en)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1389473A1 (en) * 2002-08-12 2004-02-18 Maco Pharma Device and method for irreversible closure of fluid communication in a container system
US8262639B2 (en) 2002-01-31 2012-09-11 Fenwal, Inc. Irreversible flow control clamp
US8517970B2 (en) 2002-01-31 2013-08-27 Fenwal, Inc. Irreversibly closable flow control clamp and fluid processing set
US9833606B2 (en) 2012-09-07 2017-12-05 Fenwal, Inc. Non-reopenable flow control clamp

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5270003A (en) * 1992-11-20 1993-12-14 Baxter International Inc. Blood sampling system

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002028A1 (en) * 1977-11-11 1979-05-30 Walter Sarstedt Kunststoff-Spritzgusswerk Device for extracting blood
US4676783A (en) * 1985-09-03 1987-06-30 The University Of Virginia Alumni Patents Foundation Retractable safety needle
WO1987006813A1 (en) * 1986-05-14 1987-11-19 Lamberto Roberti Needle for multiple vacuum blood sample devices
WO1989009025A1 (en) * 1988-03-31 1989-10-05 Maria Hansby Blood collecting unit and its use
EP0356002A2 (en) * 1988-07-20 1990-02-28 City Of Hope Needle protectors for a blood collection apparatus

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0002028A1 (en) * 1977-11-11 1979-05-30 Walter Sarstedt Kunststoff-Spritzgusswerk Device for extracting blood
US4676783A (en) * 1985-09-03 1987-06-30 The University Of Virginia Alumni Patents Foundation Retractable safety needle
WO1987006813A1 (en) * 1986-05-14 1987-11-19 Lamberto Roberti Needle for multiple vacuum blood sample devices
WO1989009025A1 (en) * 1988-03-31 1989-10-05 Maria Hansby Blood collecting unit and its use
EP0356002A2 (en) * 1988-07-20 1990-02-28 City Of Hope Needle protectors for a blood collection apparatus

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8262639B2 (en) 2002-01-31 2012-09-11 Fenwal, Inc. Irreversible flow control clamp
US8517970B2 (en) 2002-01-31 2013-08-27 Fenwal, Inc. Irreversibly closable flow control clamp and fluid processing set
US8956339B2 (en) 2002-01-31 2015-02-17 Fenwal, Inc. Irreversibly closable flow control clamp
US9498616B2 (en) 2002-01-31 2016-11-22 Fenwal, Inc. Irreversibly closable flow control clamp
US9789301B2 (en) 2002-01-31 2017-10-17 Fenwal, Inc. Irreversibly closable flow control clamp
US10335586B2 (en) 2002-01-31 2019-07-02 Fenwal, Inc. Irreversibly closable flow control clamp
EP1389473A1 (en) * 2002-08-12 2004-02-18 Maco Pharma Device and method for irreversible closure of fluid communication in a container system
US9833606B2 (en) 2012-09-07 2017-12-05 Fenwal, Inc. Non-reopenable flow control clamp

Also Published As

Publication number Publication date
SE9201738L (en) 1993-12-06
AU4364593A (en) 1994-01-04
FI940523L (en) 1994-02-04
FI940523A0 (en) 1994-02-04
JPH06509735A (en) 1994-11-02
PL302314A1 (en) 1994-07-25
CZ50294A3 (en) 1994-06-15
CA2114324A1 (en) 1993-12-23
SE502351C2 (en) 1995-10-09
RU94016157A (en) 1996-05-20
EP0606425A1 (en) 1994-07-20
BG98485A (en) 1994-09-30
SK27094A3 (en) 1994-08-10
FI940523A7 (en) 1994-02-04
SE9201738D0 (en) 1992-06-05

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