WO1995007466A3 - Biotin-analog conjugated antibodies for positive cell selection and release - Google Patents

Biotin-analog conjugated antibodies for positive cell selection and release Download PDF

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Publication number
WO1995007466A3
WO1995007466A3 PCT/US1994/010124 US9410124W WO9507466A3 WO 1995007466 A3 WO1995007466 A3 WO 1995007466A3 US 9410124 W US9410124 W US 9410124W WO 9507466 A3 WO9507466 A3 WO 9507466A3
Authority
WO
WIPO (PCT)
Prior art keywords
release
cell selection
positive cell
biotin
conjugated antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1994/010124
Other languages
French (fr)
Other versions
WO1995007466A2 (en
Inventor
Fahad A Al-Abdaly
Yu-An Chang
Roy Guillermo
William H Scouten
Alan K Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter International Inc filed Critical Baxter International Inc
Priority to JP7508792A priority Critical patent/JPH09502351A/en
Priority to EP94929156A priority patent/EP0717848A1/en
Priority to AU78320/94A priority patent/AU7832094A/en
Publication of WO1995007466A2 publication Critical patent/WO1995007466A2/en
Publication of WO1995007466A3 publication Critical patent/WO1995007466A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

The invention provides a stable conjugate of a target cell binding protein, preferably an antibody, covalently linked to a biotin analog moiety for use in positive cell selection and release. Methods for positive cell selection and release using the stable conjugate are described.
PCT/US1994/010124 1993-09-08 1994-09-08 Biotin-analog conjugated antibodies for positive cell selection and release Ceased WO1995007466A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP7508792A JPH09502351A (en) 1993-09-08 1994-09-08 Biotin analog conjugated antibody for positive cell selection and release
EP94929156A EP0717848A1 (en) 1993-09-08 1994-09-08 Biotin-analog conjugated antibodies for positive cell selection and release
AU78320/94A AU7832094A (en) 1993-09-08 1994-09-08 Biotin-analog conjugated antibodies for positive cell selection and release

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11806893A 1993-09-08 1993-09-08
US08/118,068 1993-09-08

Publications (2)

Publication Number Publication Date
WO1995007466A2 WO1995007466A2 (en) 1995-03-16
WO1995007466A3 true WO1995007466A3 (en) 1995-04-06

Family

ID=22376345

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/010124 Ceased WO1995007466A2 (en) 1993-09-08 1994-09-08 Biotin-analog conjugated antibodies for positive cell selection and release

Country Status (5)

Country Link
EP (1) EP0717848A1 (en)
JP (1) JPH09502351A (en)
AU (1) AU7832094A (en)
CA (1) CA2168205A1 (en)
WO (1) WO1995007466A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5518882A (en) * 1993-12-21 1996-05-21 Biotex Laboratories, Inc. Immunological methods of component selection and recovery
US6017719A (en) * 1994-06-14 2000-01-25 Nexell Therapeutics, Inc. Positive and positive/negative cell selection mediated by peptide release
WO1997044666A1 (en) * 1996-05-17 1997-11-27 Cytovax Biotechnologies Inc. Immunological methods of component selection and recovery
AU2001274931B2 (en) * 2000-05-23 2006-03-30 Nexell Therapeutics, Inc. Reagents for cell selection and methods of use
US20040259153A1 (en) * 2001-08-22 2004-12-23 Yoshikazu Kurosawa Methods for selecting biding molecule
US7956165B2 (en) 2003-07-24 2011-06-07 Affisink Biotechnology Ltd. Compositions and methods for purifying and crystallizing molecules of interest
EP2518193A3 (en) * 2006-11-15 2013-01-23 Invitrogen Dynal AS Methods for reversibly binding a biotin compound to a support
WO2015195404A1 (en) 2014-06-20 2015-12-23 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for detection of an analyte by movement of tethered microparticles
WO2016205239A1 (en) 2015-06-15 2016-12-22 The United States Of America, As Represented By The Secretary Department Of Health And Human Services Non-hormonal mammalian sperm decoy contraception based on the n-terminus of the zp2 protein
JP7492826B2 (en) 2016-10-21 2024-05-30 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ Molecular Nanotags
WO2018217630A1 (en) * 2017-05-21 2018-11-29 University Of Tennessee Research Foundation Methods and compositions for targeting tissue lesions
WO2019133727A1 (en) 2017-12-29 2019-07-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Universal influenza virus probe set for enrichment of any influenza virus nucleic acid
WO2022056078A1 (en) 2020-09-11 2022-03-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Rnase h-assisted detection assay for rna (radar)
AU2023281871A1 (en) * 2022-05-31 2024-11-14 Illumina, Inc Compositions and methods for nucleic acid sequencing
WO2024191684A1 (en) 2023-03-10 2024-09-19 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Detection of hepatitis c virus ribonucleic acid from whole blood using reverse transcription loop-mediated isothermal amplification

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987004628A1 (en) * 1986-01-30 1987-08-13 Fred Hutchinson Cancer Research Center Immunoselection method
US5215927A (en) * 1986-01-30 1993-06-01 Fred Hutchinson Cancer Research Center Method for immunoselection of cells using avidin and biotin

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987004628A1 (en) * 1986-01-30 1987-08-13 Fred Hutchinson Cancer Research Center Immunoselection method
US5215927A (en) * 1986-01-30 1993-06-01 Fred Hutchinson Cancer Research Center Method for immunoselection of cells using avidin and biotin

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JANE S. LEBKOWSKI ET AL.: "Rapid Isolation of Human CD34 Hematopoietic Stem Cells-Purging of Human Tumor Cells", TRANSPLANTATION, vol. 53, no. 5, May 1992 (1992-05-01), BALTIMORE, MD, US, pages 1011 - 1019 *
ORR, GEORGE A.: "The use of the 2- iminobiotin -avidin interaction for the selective retrieval of labeled plasma membrane components", J. BIOL. CHEM. (1981), 256(2), 761-6 CODEN: JBCHA3;ISSN: 0021-9258, 1981 *
R. ALAN HARDWICK ET AL.: "Design of Large-Scale Separation Systems for Positive and Negative Immunomagnetic Selection of Cells Using Superparamagnetic Microspheres", JOURNAL OF HEMATOTHERAPY, vol. 1, no. 4, 1992, pages 379 - 386 *
ROSS S. BASCH ET AL.: "Cell Separation Using Positive Immunoselctive Techniques", JOURNAL OF IMMUNOLOGICAL METHODS., vol. 56, no. 1, January 1983 (1983-01-01), NEW YORK US, pages 269 - 280 *

Also Published As

Publication number Publication date
JPH09502351A (en) 1997-03-11
WO1995007466A2 (en) 1995-03-16
AU7832094A (en) 1995-03-27
EP0717848A1 (en) 1996-06-26
CA2168205A1 (en) 1995-03-16

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