WO1995018598A1 - Pharmaceutical ointment base - Google Patents

Pharmaceutical ointment base Download PDF

Info

Publication number
WO1995018598A1
WO1995018598A1 PCT/US1995/000502 US9500502W WO9518598A1 WO 1995018598 A1 WO1995018598 A1 WO 1995018598A1 US 9500502 W US9500502 W US 9500502W WO 9518598 A1 WO9518598 A1 WO 9518598A1
Authority
WO
WIPO (PCT)
Prior art keywords
ointment base
weight
pharmaceutical ointment
paraffins
beeswax
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1995/000502
Other languages
French (fr)
Inventor
David D. Mundschenk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PhyloMed Corp
Original Assignee
PhyloMed Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PhyloMed Corp filed Critical PhyloMed Corp
Priority to EP95907432A priority Critical patent/EP0740545A4/en
Priority to AU15667/95A priority patent/AU1566795A/en
Publication of WO1995018598A1 publication Critical patent/WO1995018598A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/22—Peroxides; Oxygen; Ozone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/342—Alcohols having more than seven atoms in an unbroken chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/927—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of insects, e.g. shellac
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Insects & Arthropods (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)

Abstract

An ointment base useful as a vehicle for a broad range of medicament volumes and concentrations. The ointment base includes a stable emulsion of at least about 10 % by weight of each of water, one or more paraffins, and a liquid polyol; and less than about 10 % by weight of each of beeswax, cetostearyl alcohol, a 4-hydroxy benzoic acid lower alkyl ester, a surface active agent, and a dispersing agent.
PCT/US1995/000502 1994-01-11 1995-01-11 Pharmaceutical ointment base Ceased WO1995018598A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP95907432A EP0740545A4 (en) 1994-01-11 1995-01-11 PHARMACEUTICAL OINTMENT BASE
AU15667/95A AU1566795A (en) 1994-01-11 1995-01-11 Pharmaceutical ointment base

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/180,078 US5512278A (en) 1994-01-11 1994-01-11 Ointment base useful for pharmaceutical preparations
US08/180,078 1994-01-11

Publications (1)

Publication Number Publication Date
WO1995018598A1 true WO1995018598A1 (en) 1995-07-13

Family

ID=22659128

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/000502 Ceased WO1995018598A1 (en) 1994-01-11 1995-01-11 Pharmaceutical ointment base

Country Status (5)

Country Link
US (1) US5512278A (en)
EP (1) EP0740545A4 (en)
AU (1) AU1566795A (en)
CA (1) CA2180755A1 (en)
WO (1) WO1995018598A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997048373A1 (en) * 1996-06-20 1997-12-24 Unilever Plc Cosmetic composition containing an antiperspirant or deodorant and a moisturising cream

Families Citing this family (34)

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Publication number Priority date Publication date Assignee Title
US5599561A (en) * 1995-08-04 1997-02-04 Gonzalez, Jr.; Angel Method of making poultice
US6431180B2 (en) * 1997-10-08 2002-08-13 Laughlin Products, Inc. Automated system for coating the human body
US6881417B1 (en) 1997-10-08 2005-04-19 Laughlin Products, Inc. Method, apparatus, and composition for automatically coating the human body with plural components
US7082948B2 (en) * 1997-10-08 2006-08-01 Laughlin Products, Inc. Method of and apparatus for automatically coating the human body
US6886572B2 (en) 1997-10-08 2005-05-03 Laughlin Products, Inc. Automated system for coating the human body: virtual motion
US6439243B2 (en) * 1997-10-08 2002-08-27 Laughlin Products, Inc. Method of and apparatus for automatically coating the human body
US7041089B2 (en) * 1997-10-08 2006-05-09 Laughlin Products, Inc. Automated system for coating the human body: virtual motion
US5980925A (en) 1997-12-30 1999-11-09 Ethicon, Inc. High glycerin containing anti-microbial cleansers
US6117118A (en) * 1998-01-20 2000-09-12 Laughlin Products, Inc. Process for bleaching chemically tanned skin and discolored nails
US20020123517A1 (en) * 1998-12-01 2002-09-05 Jacobson Elaine L. Method for controlling cell necrosis or apoptosis
US6117415A (en) * 1999-06-17 2000-09-12 Alpharx Inc. Toothpaste comprising bioadhesive submicron emulsion for improved delivery of antibacterial and anticaries agents
US6802830B1 (en) * 2000-06-16 2004-10-12 Drew Waters Device and method that generates a fog capable of altering the color of human skin
IL142812A (en) * 2001-04-25 2012-12-31 Israel State High efficacy protective compositions against vesicants and percutaneous chemical agents
US20050036958A1 (en) * 2003-08-13 2005-02-17 Jianxun Feng Dental bleaching
IL157814A (en) * 2003-09-08 2007-12-03 Lev Bar Ltd Cosmetic composition comprising camel milk or components thereof
US20060198795A1 (en) * 2005-11-07 2006-09-07 Giniger Martin S Multi-component oral care compositions
PL2068816T3 (en) * 2006-09-29 2018-03-30 The Procter And Gamble Company Oral compositions containing gel networks
US8518381B2 (en) * 2008-03-28 2013-08-27 The Procter & Gamble Company Processes of making oral compositions containing gel networks
FR2931073B1 (en) * 2008-05-16 2010-08-20 Fabre Pierre Dermo Cosmetique EMOLLIENT COMPOSITION
US20110263509A1 (en) * 2008-10-07 2011-10-27 Haemopep Pharma Gmbh Preparation and use of high-purity hemoparatide (hpth-1-37) for the treatment of inflammatory scaling diseases of the skin
DE102013204683A1 (en) * 2013-03-18 2014-09-18 Beiersdorf Ag Hairstyling emulsion
CA3018598A1 (en) 2016-04-01 2017-10-05 The Procter & Gamble Company Oral care compositions containing gel networks and potassium nitrate
WO2017173198A1 (en) 2016-04-01 2017-10-05 The Procter & Gamble Company Oral care compositions containing a gel network phase
CA3018552A1 (en) 2016-04-01 2017-10-05 The Procter & Gamble Company Oral care compositions containing a gel network phase and potassium nitrate
MX2018011991A (en) 2016-04-01 2019-02-13 Procter & Gamble Oral care compositions with an effective flavor display.
BR112018069979A2 (en) 2016-04-01 2019-02-05 Procter & Gamble mouthwash compositions containing potassium nitrate and peroxide
RU2019107791A (en) 2016-10-26 2020-09-21 Дзе Проктер Энд Гэмбл Компани MULTI-PHASE COMPOSITION FOR ORAL APPLICATION FOR DELIVERY OF ACTIVE SUBSTANCES FOR CARE OF THE ORAL CAVITY
AU2020263241B2 (en) 2019-04-25 2023-04-13 The Procter & Gamble Company Rinseable multi-phase compositions
MX2021011296A (en) 2019-04-25 2021-10-13 Procter & Gamble Oral care compositions for active agent delivery.
US20200345597A1 (en) 2019-04-25 2020-11-05 The Procter & Gamble Company Systems And Methods For Delivering Active Agents
CN112439071B (en) * 2019-09-04 2022-05-20 武汉科福新药有限责任公司 Transdermal penetration-promoting composition and application thereof in timolol preparation
US11857676B1 (en) * 2020-08-20 2024-01-02 ORCA Products, LLC Compositions for oral pain relief
US12447115B2 (en) 2021-09-20 2025-10-21 The Procter & Gamble Company Jammed emulsion toothpaste compositions
US12496262B2 (en) 2021-09-20 2025-12-16 The Procter & Gamble Company Jammed emulsion toothpaste compositions

Citations (1)

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US5145604A (en) * 1990-09-19 1992-09-08 S. C. Johnson & Son, Inc. Aqueous emulsion and aerosol delivery system using same

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Patent Citations (1)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997048373A1 (en) * 1996-06-20 1997-12-24 Unilever Plc Cosmetic composition containing an antiperspirant or deodorant and a moisturising cream
US6221345B1 (en) 1996-06-20 2001-04-24 Helene Curtis, Inc. Cosmetic composition

Also Published As

Publication number Publication date
AU1566795A (en) 1995-08-01
CA2180755A1 (en) 1995-07-13
US5512278A (en) 1996-04-30
EP0740545A4 (en) 1997-10-15
EP0740545A1 (en) 1996-11-06

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