WO1996024650A3 - Cytoplasmic antiproteinase-2 and cytoplasmic antiproteinase-3 and coding sequences - Google Patents

Cytoplasmic antiproteinase-2 and cytoplasmic antiproteinase-3 and coding sequences Download PDF

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Publication number
WO1996024650A3
WO1996024650A3 PCT/US1996/001288 US9601288W WO9624650A3 WO 1996024650 A3 WO1996024650 A3 WO 1996024650A3 US 9601288 W US9601288 W US 9601288W WO 9624650 A3 WO9624650 A3 WO 9624650A3
Authority
WO
WIPO (PCT)
Prior art keywords
cytoplasmic antiproteinase
antiproteinase
cytoplasmic
coding sequences
proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US1996/001288
Other languages
French (fr)
Other versions
WO1996024650A2 (en
Inventor
Cindy A Sprecher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to AU49110/96A priority Critical patent/AU4911096A/en
Priority to EP96905309A priority patent/EP0808351A2/en
Priority to JP8524312A priority patent/JPH10513062A/en
Publication of WO1996024650A2 publication Critical patent/WO1996024650A2/en
Publication of WO1996024650A3 publication Critical patent/WO1996024650A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Cytoplasmic Antiproteinase-2 and Cytoplasmic Antiproteinase-3 nucleic acids and serine protease inhibitor proteins encoded thereby are useful in the purification of proteins and in the treatment of inflammatory diseases and diseases involving apoptosis.
PCT/US1996/001288 1995-02-08 1996-02-02 Cytoplasmic antiproteinase-2 and cytoplasmic antiproteinase-3 and coding sequences Ceased WO1996024650A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU49110/96A AU4911096A (en) 1995-02-08 1996-02-02 Cytoplasmic antiproteinase-2 and cytoplasmic antiproteinase-3 and coding sequences
EP96905309A EP0808351A2 (en) 1995-02-08 1996-02-02 Cytoplasmic antiproteinase-2 and cytoplasmic antiproteinase-3 and coding sequences
JP8524312A JPH10513062A (en) 1995-02-08 1996-02-02 Cytoplasmic antiproteinase-2 and cytoplasmic antiproteinase-3 and coding sequence

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/385,500 US5712117A (en) 1995-02-08 1995-02-08 Cytoplasmic antiproteinase-2 and coding sequences
US08/385,500 1995-02-08

Publications (2)

Publication Number Publication Date
WO1996024650A2 WO1996024650A2 (en) 1996-08-15
WO1996024650A3 true WO1996024650A3 (en) 1997-06-19

Family

ID=23521641

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/001288 Ceased WO1996024650A2 (en) 1995-02-08 1996-02-02 Cytoplasmic antiproteinase-2 and cytoplasmic antiproteinase-3 and coding sequences

Country Status (6)

Country Link
US (4) US5712117A (en)
EP (1) EP0808351A2 (en)
JP (1) JPH10513062A (en)
AU (1) AU4911096A (en)
CA (1) CA2212386A1 (en)
WO (1) WO1996024650A2 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8715645B2 (en) * 1994-05-27 2014-05-06 The Regents Of The University Of Colorado Viral vectors encoding apoptosis-inducing proteins and methods for making and using the same
US5712117A (en) * 1995-02-08 1998-01-27 Zymogenetics, Inc. Cytoplasmic antiproteinase-2 and coding sequences
DE19607210A1 (en) * 1996-02-26 1997-08-28 Knoll Ag Process for the purification of thrombin-like proteases from snake venoms
US5869259A (en) * 1997-06-09 1999-02-09 Incyte Pharmaceuticals, Inc. Carboxypeptidase inhibitor
WO1999009206A1 (en) * 1997-08-18 1999-02-25 Center For Blood Research, Inc. Methods for using granzymes and binding molecules thereof for treating diseases characterized by abnormal apoptosis
AU3866799A (en) * 1998-05-04 1999-11-23 Zymogenetics Inc. Cytoplasmic antiproteinase-3 coding sequence in gene therapy
US6849605B1 (en) 1999-03-05 2005-02-01 The Trustees Of University Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of viral infections
AU3731400A (en) 1999-03-05 2000-09-21 Trustees Of University Technology Corporation, The Methods and compositions useful in inhibiting apoptosis
US6489308B1 (en) 1999-03-05 2002-12-03 Trustees Of University Of Technology Corporation Inhibitors of serine protease activity, methods and compositions for treatment of nitric-oxide-induced clinical conditions
AU3864000A (en) * 1999-03-05 2000-09-21 Trustees Of University Technology Corporation, The Inhibitors of serine protease activity, methods and compositions for treatment of herpes viruses
WO2002010190A2 (en) * 2000-07-29 2002-02-07 Genaissance Pharmaceuticals, Inc. Haplotypes of the il12b gene
CA2458303A1 (en) * 2001-09-17 2003-03-27 Janssen Pharmaceutica N.V. Brain expressed cap-2 gene and protein associated with bipolar disorder
US20040220242A1 (en) * 2003-05-02 2004-11-04 Leland Shapiro Inhibitors of serine protease activity, methods and compositions for treatment of nitric oxide induced clinical conditions
PL2520654T3 (en) * 2003-08-26 2017-08-31 The Regents Of The University Of Colorado, A Body Corporate Inhibitors of serine protease activity and their use in methods and compositions for treatment of bacterial infections
ES2412729T3 (en) 2009-10-28 2013-07-12 Juan Dominguez-Montes Stereoscopic Reproduction System
KR20200044138A (en) 2011-06-24 2020-04-28 더 리젠츠 오브 더 유니버시티 오브 콜로라도, 어 바디 코포레이트 Compositions, methods and uses for alpha-1 antitrypsin fusion molecules
JP2015504675A (en) 2012-01-10 2015-02-16 ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド，ア ボディー コーポレイトＴＨＥ ＲＥＧＥＮＴＳ ＯＦ ＴＨＥ ＵＮＩＶＥＲＳＩＴＹ ＯＦ ＣＯＬＯＲＡＤＯ，ａ ｂｏｄｙ ｃｏｒｐｏｒａｔｅ Compositions, methods, and uses of alpha-1 antitrypsin fusion molecules
FR3042501B1 (en) * 2015-10-16 2017-11-03 Roquette Freres NOVEL METHYLATED CYCLODEXTRINS AND PROCESSES FOR THEIR PREPARATION

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5712117A (en) * 1995-02-08 1998-01-27 Zymogenetics, Inc. Cytoplasmic antiproteinase-2 and coding sequences

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MORGENSTERN K A ET AL: "Complementary DNA cloning and kinetic characterization of a novel intracellular serine proteinase inhibitor: Mechanism of action with trypsin and factor Xa as model proteinases.", BIOCHEMISTRY 33 (11). 1994. 3432-3441. ISSN: 0006-2960, XP002006165 *
SPRECHER C A ET AL: "Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors.", JOURNAL OF BIOLOGICAL CHEMISTRY 270 (50). 1995. 29854-29861. ISSN: 0021-9258, XP002006166 *

Also Published As

Publication number Publication date
US5747645A (en) 1998-05-05
US5710026A (en) 1998-01-20
US5712117A (en) 1998-01-27
WO1996024650A2 (en) 1996-08-15
US5578705A (en) 1996-11-26
AU4911096A (en) 1996-08-27
EP0808351A2 (en) 1997-11-26
JPH10513062A (en) 1998-12-15
CA2212386A1 (en) 1996-08-15

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